• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3581-3585
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• 2013

Background: Accurate statistics on the cancer burden are essential, both for purposes of research and for setting priorities in healthcare management. So that in vast countries with partial registration coverage, such as Iran, local data are more useful. We here estimated the incidence, prevalence and mortality time trend of four major cancer site, lung, stomach, breast and prostate, over the period 2001-2010 and provided short-range projections to 2015 in Isfahan. Materials and Methods: Estimates were derived by applying the mortality-incidence analysis method, a back-calculation approach to estimate and project incidence, prevalence and mortality of chronic degenerative disease, starting from knowledge of mortality and relative survival information. Results: Age adjusted incidence, mortality and prevalence rates in Isfahan exhibited a clear upward trend for all four sites during the period 2001-2015, with marked increasees in prostate and breast predicted for the future. Difference in incidence trends between males and females might be attributable to the difference in risk factors specific to certain cancer sites, with smoking being the main risk factor. Conclusions: In this study, males and females displayed an increasing pattern for incidence and mortality rate over the entire study period until 2015. This information can be used as basis for planning healthcare management and allocating recourses in public health.

• 지역사회간호학회지
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• 제23권1호
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• pp.31-39
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• 2012

Purpose: The purpose of this paper was to compare community health status by region and to investigate related factors using community health and social indicators. Methods: Data were collected from statistics of local districts that were provided by KNSO and KCDC. ANOVA and correlation were analyzed using PASW 18.0. Results: The standardized cancer mortality rate was higher in metropolitan areas than in other areas. On the contrary, the mortality of respiratory disease, traffic accident, and suicide were higher in rural areas. Small cities and county districts showed higher prevalence in obesity prevalence than metropolitan areas. Metropolitan areas presented higher prevalence in alcohol drinking during the previous month, perceived stress, and seat belt use. The age-adjusted standardized mortality rate was correlated with higher prevalence of smoking, obesity, percentage of the elderly, number of beds, number of social welfare facilities, number of registered cars, lower percentage of financial independence, number of doctors, and percentage of water supply service & sewage. Conclusion: Since significant differences in mortality rate and prevalence of health risk behaviors exist between regional areas and the mortality rate was correlated with other social indicators and health indicators, health policies and social policies considering these differences should be develop and implemented to the communities.

• Journal of Korean Biological Nursing Science
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• 제21권4호
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• pp.300-307
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• 2019

Purpose: The purpose of this study was to provide basic data on the infection prevention management program, which is one of the infectious disease control program by identifying the prevalence and risk factors of latent tuberculosis infection (LTBI) in healthcare workers. Methods: We surveyed a total of 3,046 LTBI test results, including those of 2,269 existing staff and 777 new employees. An interferon-gamma release assay (IGRA) for the diagnosis of LTBI was performed using QuantiFERON^®-TB Gold In-Tube (QFT-IT). The risk factors of LTBI were analyzed using logistic regression analysis. Results: The overall prevalence of LTBI was 16.0% (487/3,046). The prevalence of LTBI in the existing staff was 17.9% (406/2,269) and the prevalence of LTBI in new employees was 10.4% (81/777). Multivariate logistic regression analysis revealed that the risk factors of latent tuberculosis infection among the existing staff were gender, age and work period wheres, the risk factor amongst the new employees depended on their age. Conclusion: The LTBI was not related to the type of occupation and work unit. Therefore, while establishing an infection control program for the prevention of tuberculosis infection at medical institurions, institutional heads and infection control experts should encompass a policy for all the employees.

• Journal of Genetic Medicine
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• 제15권2호
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• pp.110-114
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• 2018

Ataxia-telangiectasia (AT; OMIM 208900) is a rare autosomal recessive inherited progressive neurodegenerative disorder, with onset in early childhood. AT is caused by homozygous or compound heterozygous mutations in ATM (OMIM 607585) on chromosome 11q22. The average prevalence of the disease is estimated at 1 of 100,000 children worldwide. The prevalence of AT in the Republic of Korea is suggested to be extremely low, with only a few cases genetically confirmed thus far. Herein, we report a 5-year-old Korean boy with clinical features such as progressive gait and truncal ataxia, both ankle spasticity, dysarthria, and mild intellectual disability. The patient was identified as a compound heterozygote with two novel genetic variants: a paternally derived c.5288_5289insGA p.(Tyr1763*) nonsense variant and a maternally derived c.8363A>C p.(His2788Pro) missense variant, as revealed by next-generation sequencing and confirmed by Sanger sequencing. Based on claims data from the Health Insurance Review and Assessment Service Republic of Korea, we calculated the prevalence of AT in the Republic of Korea to be about 0.9 per million individuals, which is similar to the worldwide average. Therefore, we suggest that multi-gene panel sequencing including ATM should be considered early diagnosis.

• 산경연구논집
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• 제12권9호
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• pp.7-18
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• 2021

Purpose: This study aims to investigate whether there is a difference in the prevalence of hypertension according to gender, occupational group, and occupational group according to gender. Research design, data, and methodology: This study classified the occupational groups according to the gender of men and women between the ages of 20 and 49 into office workers and non-office workers from the 7th 2017 National Health and Nutrition Examination Survey. A total of 2,691 people were surveyed, including 1,394 office workers and 1,297 non-office workers. Frequency analysis, chi-square, and Independent T-test for distribution difference analysis of categorical variables analysis for occupation and hypertension were applied. Statistical significance was verified at 0.001 to determine the validity analysis. All statistical analyses were performed using the IBM SPSS 24.0 program. Results: The main risk factors for hypertension were gender, age, education, obesity, smoking, drinking, family history, and chronic diseases. There were differences in the prevalence of hypertension among office workers and non-office workers. Conclusions: Men had a higher prevalence of hypertension than women, while non-office workers had a higher prevalence than office workers. In the case of women, non-office workers have a higher prevalence of hypertension than white-collar workers.

• 한국식생활문화학회지
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• 제38권2호
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• pp.119-127
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• 2023

The labor environment in Korea has changed and problems related to employment types are treated as important issues. Especially, the ratio of irregular workers has not only increased relatively, but the labor conditions in Korea also have worsened in the current years. Studies have reported an association between temporary workers and the prevalence of diseases. However, there is insufficient research on chronic disease and employment types. Methods: The current study examines the prevalence rate of diseases and health behavior by categorizing employment types among Korean adults. Data were obtained from the 2016-2018 Korea National Health and Nutrition Examination Survey. Totally, the data of 2,366 workers (1,239 regular and 1,127 irregular) were analyzed in the study. The types of employment were classified by a questionnaire querying about working conditions. The results showed that irregular workers earned less than regular workers and had a significantly higher prevalence of diabetes mellitus and hypertension. We propose that if discrimination related to working conditions were relieved, irregular workers would be able to invest more time to exercise and doing check-ups regularly. In addition, individual nutrition consultations considering the knowledge and personal environmental factors of each individual are necessary for the improved health of all workers.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2001년도 춘계 심포지움 연제집
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• pp.83-83
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• 2001

• Parasites, Hosts and Diseases
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• 제58권3호
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• pp.257-265
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• 2020

The outbreak of human toxoplasmosis can be attributed to ingestion of food contaminated with Toxoplasma gondii. Toxoplasmosis recently increased in domestic and stray dogs and cats. It prompted studies on the zoonotic infectious diseases transmitted via these animals. Sero- and antigen prevalences of T. gondii in dogs and cats were surveyed using ELISA and PCR, and B1 gene phylogeny was analyzed in this study. Toxoplasmosis antibodies were measured on sera of 403 stray cats, 947 stray dogs, 909 domestic cats, and 2,412 domestic dogs collected at nationwide regions, Korea from 2017 to 2019. In addition, whole blood, feces, and tissue samples were also collected from stray cats (1,392), stray dogs (686), domestic cats (3,040), and domestic dogs (1,974), and T. gondii-specific B1 gene PCR was performed. Antibody prevalence of stray cats, stray dogs, domestic cats, and domestic dogs were 14.1%, 5.6%, 2.3%, and 0.04%, respectively. Antigen prevalence of these animals was 0.5%, 0.2%, 0.1%, and 0.4%, respectively. Stray cats revealed the highest infection rate of toxoplasmosis, followed by stray dogs, domestic cats, and domestic dogs. B1 gene positives were 5 of stray cats, and identified to high/moderate pathogenic Type I/III group. These findings enforce that preventive hygienic measure should be strengthened at One Health level in dogs and cats, domestic and stray, to minimize human toxoplasmosis infections.

• Journal of Korean Biological Nursing Science
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• 제13권3호
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• pp.262-268
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• 2011

Purpose: The purpose of this study was to identify the relationship between health behaviors and musculoskeletal disease in adults. Methods: The data of 7,421 adults applied in this study were collected from health behaviors (smoking, drinking, exercise, weight, sleeping, stress) and related with musculoskeletal disease form 2009 Korea National Health and Nutrition Examination Survey. Date were collected through self-report questionnaires from January to December, 2009. Data were analyzed using chi-square test, Multivariate logistic regression with SPSS/WIN 17.0. Results: The prevalence rate of musculoskeletal disease was 30.6%. In multivariate analyses, the sex, age, BMI, stress and education were statistically strongly associated with most of musculoskeletal disease among adults. Conclusion: The results of this study suggest that musculoskeletal disease prevention and nursing intervention programs should be necessarily established and continuously managed in order to treat with the musculoskeletal disease.

• Clinical and Experimental Pediatrics
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• 제56권8호
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• pp.338-342
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• 2013

Purpose: Allergic disease and its comorbidities significantly influence the quality of life. Although the comorbidities of allergic diseases are well described in adult populations, little is known about them in preschool children. In the present study, we aimed to assess the prevalence and comorbidity of allergic diseases in Korean preschool children. Methods: We conducted a cross-sectional study comprising 615 Korean children (age, 3 to 6 years). Symptoms of allergic diseases were assessed using the Korean version of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire that was modified for preschool children. Comorbidities of allergic diseases were assessed by 'In the last 12 months, has your child had symptoms?'. Results: The prevalence of symptoms of asthma, allergic rhinitis, and atopic dermatitis as recorded using the ISAAC questionnaire, within the last 12 months was 13.8%, 40.7%, and 20.8%, respectively. The symptom rates of allergic conjunctivitis, food allergy, and drug allergy were 14.8%, 10.4%, and 0.8%, respectively. The prevalence of allergic rhinitis in children with asthma was 64.3% and that of asthma in children with allergic rhinitis was 21.6%. The prevalence of rhinitis in children with conjunctivitis was 64.8% and that of conjunctivitis in children with rhinitis was 23.6%. Conclusion: The prevalence of current rhinitis in our preschool children is shown to be higher than that previously reported. Allergic conjunctivitis is closely associated with asthma and allergic rhinitis. However, further studies are warranted to determine the prevalence and effects of these comorbidities on health outcomes in preschool children.