• Title/Summary/Keyword: disease pattern

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The Influence of General Characteristic in Patients with Low Back Pain on the Psychologic Status (요통 환자의 일반적인 특성이 요통의 심리적 측면에 미치는 영향)

  • Han Dong-Wook;Park Ji-Whan;Kim Yong-Gun
    • The Journal of Korean Physical Therapy
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    • v.14 no.3
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    • pp.407-417
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    • 2002
  • The purpose of this study was to examine the influence of general characteristic of the patient with low back pain on the psychologic Status. The Questionnaires was done for 312 persons with low back pain who live in Daejeon. The study was conducted between 1st, June and 26th, July in 2000. The results were as follows: 1. The effects of general characteristic of the patient with low back pain on the psychologic Status were related age(p<0.01), education level(p<0.01), job(p<0.01), husband and wife existence(p<0.01), disease(p<0.01). 2. The influence of an item on Handler score was related the reason of pain(r=0.377, p<0.01), the site and pattern of pain(r=0.314, p<0.01), the influence of climate(r=0.370, p<0.01), the frequency of pain(r=0.396, p<0.01), the position of producible pain(r=0.411, p<0.01), one's desire(r=0.394, p<0.01), experience of pessimism(r=0.421, p<0.01).

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Effects of OnDam-TanghapChongMyoung-Tang and DoDam-TanghapChongMyoung-Tang on Protecting Microglia and Inhibiting Acetylcholinesterase and Oxidants (온담탕합총명탕(溫膽湯合聰明湯)과 도담탕합총명탕(導痰湯合聰明湯)의 microglia 보호, 항산화 및 acetylcholinesterase 억제효과)

  • Cheong, Myong-Hee;Jung, In-Chul
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.5
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    • pp.1276-1282
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    • 2008
  • This experiment was designed to investigate the effect of the ODTCMT and DDTCMT extract on protecting microglia and inhibiting acetylcholinesterase and oxidants. The effects of the ODTCMT and DDTCMT extract on cell death of BV2 microglial cell line treated by $IFN-{\gamma}$ ; expression of NO, ROS in BV2 microglial cell line treated by lipopolysaccharide (LPS) ; AChE activity in PC-12 cell treated by NGF were investigated, respectively. The ODTCMT and DDTCMT extract significantly increased cell viability in BV2 microglial cell line treated with $IFN-\nu$. The ODTCMT and DDTCMT extract suppressed the NO and RDS production in BV2 microglial cell line treated by LPS. The ODTCMT and DDTCMT extract groups also showed inhibition of AChE activity in PC-12 cell line. According to the above result, it is suggested that the ODTCMT and DDTCMT extract might be usefully applied for prevention and treatment of Alzheimer's disease. OnDam-TanghapChongMyoung-Tang (ODTCMT), DoDam-TanghapChongMyoung-Tang (DDTCMT), Microglia, acetylcholinesterase, ROS

Genetics of Fusarium Wilt Resistance in Pigeonpea (Cajanus cajan) and Efficacy of Associated SSR Markers

  • Singh, Deepu;Sinha, B.;Rai, V.P.;Singh, M.N.;Singh, D.K.;Kumar, R.;Singh, A.K.
    • The Plant Pathology Journal
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    • v.32 no.2
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    • pp.95-101
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    • 2016
  • Inheritance of resistance to Fusarium wilt (FW) disease caused by Fusarium udum was investigated in pigeonpea using four different long duration FW resistant genotypes viz., BDN-2004-1, BDN-2001-9, BWR-133 and IPA-234. Based on the $F_2$ segregation pattern, FW resistance has been reported to be governed by one dominant gene in BDN-2004-1 and BDN-2001-9, two duplicate dominant genes in BWR-133 and two dominant complimentary genes in resistance source IPA-234. Further, the efficacy of six simple sequence repeat (SSR) markers namely, ASSR-1, ASSR-23, ASSR-148, ASSR-229, ASSR-363 and ASSR-366 reported to be associated with FW resistance were also tested and concluded that markers ASSR-1, ASSR-23, ASSR-148 will be used for screening of parental genotypes in pigeonpea FW resistance breeding programs. The information on genetics of FW resistance generated from this study would be used, to introgress FW resistance into susceptible but highly adopted cultivars through marker-assisted backcross breeding and in conventional breeding programs.

Genotypic Characterization of Cherry Witches' Broom Pathogen Taphrina wiesneri Strains (벚나무 빗자루병균 Taphrina wiesneri의 유전적 특성)

  • Seo, Sang-Tae;Jeong, Su-Jee;Lee, Seung-Kyu;Kim, Kyung-Hee
    • Research in Plant Disease
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    • v.17 no.1
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    • pp.99-101
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    • 2011
  • The ascomycetous fungus Taphrina wiesneri, the pathogen of cherry witches' broom, is highly pathogenic to Prunus yedoensis, the most widely planted cherry trees in Korea as park and roadside trees. A collection of 13 strains of the pathogen in Korea and Japan was characterized by 18S rDNA gene sequence and restriction fragment length polymorphism (RFLP) analysis. In cluster analysis based on 18S rDNA gene sequence the strains were divided into 2 clusters. In RFLP analysis of the rDNA-IGS region using HhaI, the strains were separated into four patterns, B, C, D and G, of which pattern G was new.

Emergency Coronary Artery Bypass Following Unsuccessful Percutaneous Transluminal Coronary Angioplasty -A Case Report- (경피적 관상동맥성형술후 응급 관상동맥 우회로 조성술 경험)

  • 안욱수
    • Journal of Chest Surgery
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    • v.21 no.2
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    • pp.373-378
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    • 1988
  • Since the introduction of percutaneous; transluminal coronary angioplasty[PTCA] by Grunt-zig in 1977, this is widely used in some patients with coronary artery disease and is an effective alternative to surgery for many patients. Indications for emergency coronary artery bypass graft[CABG] after PTCA are prolonged chest pain, worsening of coronary artery obstruction, "current of injury" by electrocardiogram, cardiogenic shock, and in a lesser incidence, ventricular fibrillation, coronary artery dissection[without obstruction], heart block, and intractable cardiac arrest. Recently, we have experienced one case of emergency CABG following unsuccessful PTCA. The patient was 54 year-old male and admitted with complaint of angina pectoris. The routine electrocardiogram revealed within normal limit. The treadmill test revealed severe chest pain after 2 min. exercise. Coronary cineangiogram revealed 95% segmental stenosis of the proximal right coronary artery. Our cardiologist was planned PTCA. During PTCA, severe chest pain and ischemic pattern on electrocardiogram were developed. But they were not relieved even by morphine and nitroglycerin till 90 min. So we performed emergency single coronary artery bypass graft from aorta to proximal right coronary artery with great saphenous vein. The patient had an excellent postoperative recovery and was free from anginal attack. He has shown striking improvement in general status[NYHA functional class 1] during 6 months after operation.operation.

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A Case of Extranodal NK/T-cell Lymphoma, Nasal Type of the Oropharynx and Supraglottis (구인두와 성문상부에 발생한 결절 외 비성 NK/T 세포 림프종 1예)

  • Baek, Hun Hee;Lim, Sung Hwan;Lee, Mi Ji;Kim, Seung Woo
    • Korean Journal of Head & Neck Oncology
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    • v.33 no.1
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    • pp.35-38
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    • 2017
  • The extranodal nasal NK/T-cell lymphoma was formerly known as lethal midline granuloma due to its most common clinical pattern like a destructive midline facial tumor. It often spread to other extranodal sites, such as skin, soft tissue, testis, upper respiratory tract, and gastrointestinal tract etc. For this reason, the term of extranodal NK/T-cell lymphoma, nasal type is preferred. Its disease entity may have a prominent admixture of inflammatory cells and necrotic tissues, further causing difficulty in diagnosis. A 44-year-old man was visited to our clinic with complaints of dysphagia and odynophagia during six months. He underwent three times punch biopsies and then, two times incisional biopsies. Finally, He was diagnosed as extranodal NK/T-cell lymphoma, nasal type involving oropharynx and supraglottis. We report an extremely rare case of extranodal NK/T-cell lymphoma, nasal type occurred in oropharynx and supraglottis with a brief review of literature.

Characteristics, Stability and Reisolation of nit Mutant of Fusarium oxysporum from Strawberry (딸기로부터 분리된 Fusarium oxysporum nit 변이주의 특성과 안정성 및 재분리)

  • 신동범;홍연규;조재민
    • Korean Journal Plant Pathology
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    • v.14 no.6
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    • pp.583-588
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    • 1998
  • This study was conducted to investigate the potential of nitrate-nonutilizing mutants (nit mutants) in ecological studies of Fusarium disease of strawberry. Nit mutants of Fusarium oxysporum from strawberry were easily formed on chlorate-containing media. Nit mutants were assigned to three phenotypic classes, nit1, nit3, and NitM, on the basis of their growth on media containing one of the following five different nitrogen sources ; nitrate, nitrite, hypoxanthine, ammonium and uric acid. Frequency of nit mutation and proportion of three phenotypes of nit mutants depended on the isolate. Mutation rate was 45.6% and ranged from 15.0% to 95.0%. The frequency of nit1 mutants was higher than that of nit3 or NitM. The complementary reaction between nit1 and NitM was higher than that of other combination. There has been no complementary response observed between nit3 and nit3. The nit mutants showed similar growth pattern as the that of wild type isolate on potato sucrose agar and potato sucrose liquid media. Most of the mutants retained pathogenicity, and maintained their phenotypes even after two year preservation through subculture on slanted PSA at room temperature. Nit mutants were selctively isolated from infested soil and infected plants on the selective medium (MMCPA) containing potassium chlorate with their original phenotypes, while naturally occurring isolates of Fusarium oxysporum were not grow on the medium. On the contrary, nit mutants showed very slight growth on the medium (MMPA) containing nitrate as a sole nitrogen source, and therefore could be distinguished from wild type isolate.

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Global Approaches to Identify Genes Involved during Infection Structure Formation in Rice Blast Fungus, Magnaporthe grisea

  • Park, Woo-Bong
    • The Plant Pathology Journal
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    • v.19 no.1
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    • pp.34-42
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    • 2003
  • The ascomycete Magnaporthe grisea is a pathogen of rice blast and is known to form specialized infection structures called appressoria for successful infection into host cells. To understand the molecular mechanism underlying infection process, appressorium-related genes were identified through global approaches including EST sequencing, differential hybridization, and sup-pression subtractive hybridization. EST database was generated on >2,000 cDNA clones randomly selected from appressorium stage cDNA library. Large number of ESTs showed homology to known proteins possibly involved in infection-related cellular development (attachment, germination, appressorium formation, and colonization) of rice blast fungus. The 1051 ESTs showing significant homology to known genes were assigned to 11 functional categories. Differential hybridization and suppression subtractive hybridization were applied to identify genes showing an appressorium stage specific expression pattern. A number of genes were selected as up-regulated during appressorium formation compared with the vegetative growing stage. Clones from various cDNA libraries constructed in different developmental stages were arrayed on slide glass for further expression profiling study. functional characterization of genes identified from these global approaches may lead to a better understand-ing of the infection process of this devastating plant disease, and the development of novel ways to protect host plant.

Clinical Observation on Subacute Thyroiditis (아급성(亞急性) 갑상선염(甲狀腺炎)의 임상적(臨床的) 고찰(考察))

  • Kim, Sam-Yong;Jung, Jun-Ki;Suk, Chang-Ho;Hong, Kee-Suck;Lee, Hong-Kyu;Koh, Chang-Soon;Park, Seong-Hoe;Kim, Yong-Il
    • The Korean Journal of Nuclear Medicine
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    • v.12 no.2
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    • pp.41-46
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    • 1978
  • 8 cases of subacute thyroiditis was diagnosed among 108 needle biopsy of the thyroid during the period from April 1976 to August 1978. Correlation of the histologic findings with the clinical staging proposed by Czernick was relatively well matched; cases with long clinical course or low thyroid hormone levels showed greater fibrosis and reduction of follicular elements in thyroid. Thyroid $^{131}I$ uptake or the uptake as seen on the thyroid scanning correlated inversely with the thyroid hormone levels. The clinical course of the patients seen in their initial stage of disease followed the classical pattern; hyperthyroid-like, hypothyroid-like and recovery. 3 among the 4, who were seen in their later clinical course showed hypothyroidism, which seemed the final outcome of their diseases.

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The Health service performance frequency and educational needs among the visiting nurses of public health centers (보건소 방문간호사의 서비스 수행빈도 및 교육요구)

  • Kim, Jin Hak;Song, Min Sun
    • Journal of Home Health Care Nursing
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    • v.22 no.1
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    • pp.22-37
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    • 2015
  • Purpose: This study aimed to compare the health service delivery level and educational needs by work experiences and types of public health center among the nurses who work as visiting health services workers at public health centers. Methods: Data collected from 484 nursing staff for 2 weeks, was analyzed using the SPSS program t-test, ANOVA, and Spearman Rank-Order Correlation. Nurses with more than 2 years experience were 79.1%; and 43.6% of the subjects worked within Gun type public health centers. Results: The health service performance frequency of metropolitan city type public health centers was significantly high in the areas of education, behavior pattern, chronic disease, pregnant women & infants, and multi-cultural family. The health service performance frequency of Gun type public health centers was significantly high in the areas of type of test, fundamental nursing, and basic rehabilitation. In addition, the correlation between the performance frequency and educational needs was positively correlated, and the subjects with greater educational needs performed more. Conclusion: Educational programs should be designed according to the types of public health centers rather than work experiences, especially in systematic training for frequently performed items after reviewing the practice precisely.