• 제목/요약/키워드: discriminatory

검색결과 273건 처리시간 0.027초

Providing Reliable Prognosis to Patients with Gastric Cancer in the Era of Neoadjuvant Therapies: Comparison of AJCC Staging Schemata

  • Kim, Gina;Friedmann, Patricia;Solsky, Ian;Muscarella, Peter;McAuliffe, John;In, Haejin
    • Journal of Gastric Cancer
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    • 제20권4호
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    • pp.385-394
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    • 2020
  • Purpose: Patients with gastric cancer who receive neoadjuvant therapy are staged before treatment (cStage) and after treatment (ypStage). We aimed to compare the prognostic reliability of cStage and ypStage, alone and in combination. Materials and Methods: Data for all patients who received neoadjuvant therapy followed by surgery for gastric adenocarcinoma from 2004 to 2015 were extracted from the National Cancer Database. Kaplan-Meier (KM)curves were used to model overall survival based on cStage alone, ypStage alone, cStage stratified by ypStage, and ypStage stratified by cStage. P-values were generated to summarize the differences in KM curves. The discriminatory power of survival prediction was examined using Harrell's C-statistics. Results: We included 8,977 patients in the analysis. As expected, increasing cStage and ypStage were associated with worse survival. The discriminatory prognostic power provided by cStage was poor (C-statistic 0.548), while that provided by ypStage was moderate (C-statistic 0.634). Within each cStage, the addition of ypStage information significantly altered the prognosis (P<0.0001 within cStages I-IV). However, for each ypStage, the addition of cStage information generally did not alter the prognosis (P=0.2874, 0.027, 0.061, 0.049, and 0.007 within ypStages 0-IV, respectively). The discriminatory prognostic power provided by the combination of cStage and ypStage was similar to that of ypStage alone (C-statistic 0.636 vs. 0.634). Conclusions: The cStage is unreliable for prognosis, and ypStage is moderately reliable. Combining cStage and ypStage does not improve the discriminatory prognostic power provided by ypStage alone. A ypStage-based prognosis is minimally affected by the initial cStage.

뇌졸중 환자와 노인의 의자에서 일어서기 수행평가 (5 Repetition Sit-to-Stand Test of Stroke patients and Healthy Older)

  • 권미지
    • 대한물리의학회지
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    • 제9권1호
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    • pp.101-106
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    • 2014
  • PURPOSE: This study was to provide reference data and examine stroke and healty older differences in sit-to-stand test. This study were to determine utility of the 5 repetition sit to stand for discriminating between fallers and non-fallers, identifying an appropriate cutoff score to delineate between the groups. METHODS: Ninety-five participants were recruited. Seventy-two individuals with stroke and twenty-three healthy older agreed to participate in the study. Falls were recorded using a self-administered questionnaire. The 5 repetition sit to stand test measured the time taken to complete t repetitions of the sit to stand maneuver. The time from the initial seated position to the final seated position after completing five stands was the test measure. A cutoff score regarding 5 repetition sit to stand performance in fallers vs. non-fallers, stroke patients vs. healthy older and <60 vs. $$\geq_-$$ age groups was determined using and ROC curve. RESULTS: Cutoff score of 9.9 seconds were found to be discriminatory between healthy older and subjects with stroke. Cutoff score of 15.5 seconds were found to be discriminatory between fallers and non-fallers. Cutoff score of 18.3 seconds were found to be discriminatory between <60 and $$\geq_-$$ age groups. CONCLUSION: The 5-repetition sit-to stand test is quick, easily administered measure useful for gross determination of fall risk in people with stroke.

신용평가모형에서 타당성검증 통계량들의 판단기준 (Criterion of Test Statistics for Validation in Credit Rating Model)

  • 박용석;홍종선;임한승
    • Communications for Statistical Applications and Methods
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    • 제16권2호
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    • pp.239-347
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    • 2009
  • 신용평가모형의 판별력에 대한 검정방법으로 콜모고로프-스미르노프, 평균차이, AUROC, AR등과 같은 통계량이 널리 사용되고 있다. 이러한 통계량들의 판단기준은 정규분포 가정 하에서 평균차이를 기준으로 설정되었다. 본 연구에서는 모의 실험을 통해서 표본크기, 불량률 그리고 제II종 오류율을 고려하는 대안적인 판단기준을 제 안하고 현재 적용되고 있는 판단기준과 비교해본다. 또한 판별력 정도에 따른 각 통계량들의 의미를 10단계로 정의하고 모의 실험 결과와 현재 적용되고 있는 판단기준을 비교해 본다.

HNS기반의 구성원별 자동 환경 제어 시스템에 관한 연구 (A study on the environment-controlling system by members on the basis of HNS)

  • 황선주;조대제;임한규
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2003년도 추계종합학술대회
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    • pp.720-723
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    • 2003
  • 이제까지의 디지털 홈 연구는 네트워크기술과 보안 관련 시스템에 관한 것이 주를 이루었다. 홈 네트워크에서 개인화 되고 차별화 된 서비스의 제공이 새로운 이슈로 부각되고 있다. 본 논문에서 제안하는 시스템은 가족 구성원 각자의 특성을 고려한 차별적인 서비스를 제공한다. 출입통제시스템을 통하여 내부 사용자 정보를 얻고, 컨트롤러는 내부 사용자의 데이터베이스를 활성화시켜 차별적인 환경을 제공하고, 홈 네트워크의 서브시스템을 제어하는 것이다. 예로, 사용자 연령에 따라 TV 프로그램 혹은 채널을 제한하거나 사용자마다의 다른 인터넷 환경을 제공하거나 전화번호에 제한을 둘 수 있고, 홈쇼핑 결제 권한을 제한하는 등 가족 구성원간의 차별적인 환경을 자동으로 제공할 수 있다.

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Individual Human Recognition of Wild Animals: A Review and a Case Study in the Arctic Environment

  • Lee, Won Young;Choe, Jae Chun
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • 제1권1호
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    • pp.1-8
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    • 2020
  • Recent studies revealed that many animals identify individual humans. In this account, we review previous literatures on individual human recognition by wild or domestic animals and discuss the three hypotheses: "high cognitive abilities" hypothesis, "close human contact" and "pre-exposure to stimuli" hypothesis. The three hypotheses are not mutually exclusive. Close human contact hypothesis is an ultimate explanation for adaptive benefits whereas high cognitive abilities and pre-exposure to stimuli hypothesis are proximate explanations for mechanisms to perform such discriminatory behaviour. We report a case study of two bird species in a human-free habitat. Long-tailed skuas, which are known for having high cognitive abilities, exhibited the human discriminatory abilities whereas ruddy turnstones did not display such abilities toward approaching humans. This suggests that highly intelligent species may have this type of discriminatory ability so that they could learn to identify individual humans quickly by pre-exposure to stimuli, even in a human-free habitat. Here, we discuss that human recognition is more common in species with rapid learning ability and it could develop for a short period of time between an intelligent species and human.

ICOH Statement on Protecting the Occupational Safety and Health of Migrant Workers

  • International Commission on Occupational Health (ICOH),;Salmen-Navarro, Acran;Schulte, Paul
    • Safety and Health at Work
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    • 제13권3호
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    • pp.261-262
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    • 2022
  • Globally, it is estimated that the number of people living outside of their country of origin reached 281 million in 2020. The primary drive of those migrants when migrating voluntarily is work to increase their income and provide for their families left behind in their home countries. Those who migrate immediately seek means of income to sustain themselves through a perilous process as currently evidenced in the war in Ukraine and not too long ago in Syria and Venezuela. Unfortunately, migrant workers are globally known to predominantly be working in "4-D jobs"- dirty, dangerous, and difficult and discriminatory; the fourth D was recently added to acknowledge the discriminatory aspect and other social determinants of health migrant workers face in their host country while exposed to precarious work. Consequently, migrant workers are at considerable risk of work-related illnesses and injury but their health needs are critically overlooked in research and policy. Recognizing the UN Universal Declaration of Human Rights "Everyone has the right to work, to free choice of employment, to just and favourable conditions of work and to protection against unemployment", we cannot consider any human life - thus, the life of migrant workers - as dispensable through a structural discriminatory process that undervalues their occupational safety and health, livelihood and the contribution these workers bring to their host countries. This was seen during the preparation for the upcoming world cup in Qatar where migrant workers were exposed to a multiplicity of serious hazards including deadly heat hazards.

HIV/AIDS 감염인에 대한 차별의식에 미치는 영향의 중고등학생 간 비교: 에이즈 낙인의 매개효과 (Discriminatory Attitudes towards IV/AIDS (PWHAs) Patents by Middle and High School Students)

  • 천성수;김주리;신승배;손애리
    • 한국학교ㆍ지역보건교육학회지
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    • 제9권1호
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    • pp.63-83
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    • 2008
  • 본 연구는 서울시 중고등학생을 대상으로 인구학적 특성, 에이즈감염경로지식, 동성애자에 대한 태도, 에이즈 낙인, 에이즈 감염인에 대한 사회적 거리감 사이의 인과구조를 집단별로 규명하기 위한 것이다. 중학교 8개교, 고등학교 8개교에 배포된 설문지는 3,370부 중 수거된 설문지는 3,135였고, 불성실한 설문지 34부를 제외한 총 3,101부(98.9%)가 분석에 사용되었고, 유효하지 않은 사례는 일률적(listwise)으로 제거하여 유효사례 수는 2,977부였다. 분석방법으로 탐색적 요인분석(EFA), 확인적 요인분석(CFA), 공변량 구조분석 등을 시도하였고, 모형을 추정하기 위해 구조방정식 모형을 사용하였다. 모형검증의 추정결과, 첫째, 중학생과 고등학생 간에 에이즈 차별의식의 구성개념인 에이즈 낙인과 에이즈 감염인에 대한 사회적 거리감에서 뚜렷한 차이를 보이고 있었다. 둘째, 에이즈 낙인에 대한 의생변인인 동성애자에 대한 태도는 중학생(${\beta}=.407$), 고등학생(${\beta}=.401$) 모두 강한 정(+)의 인과적 영향을 보였으며, 셋째, 에이즈 감염인에 대한 사회적 거리감의 외생변인인 동성애자에 대한 태도는 중학생(${\beta}=.108$), 고등학생(${\beta}=.080$) 모두 약한 정(+)의 영향을 보였다. 넷째, 에이즈 감염경로 지식은 중학생(${\beta}=.313$), 고등학생(${\beta}=.301$) 모두 강한 정(+)의 인과적 영향을 미쳤고, 다섯째, 에이즈 감염인에 대한 사회적 거리감에 영향을 미치는 외생변인인 에이즈 감염경로 지식은 중학생(${\beta}=.160$), 고등학생(${\beta}=.134$) 모두 정(+)의 인과적 영향을 미쳤다. 여섯째, 에이즈 감염인에 대한 사회적 거리감에 영향을 미치는 외생변인인 에이즈 낙인은 중학생(${\beta}=.616$), 고등학생(${\beta}=.692$) 모두 강한 정(+)의 인과적 영향을 미쳤다. 이상의 분석결과 에이즈 감염인에 대한 낙인 및 사회적 거리감을 해소하기 위해서는 에이즈 지식 중 감염경로에 대한 지식을 높이고, 에이즈를 동성애자의 병으로 바라보는 시각을 해소시키는 것이 필요하다고 판단된다.

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효율적인 인덱싱 기법을 이용한 3차원 물체 인식:Part I-Bayesian 인덱싱 (Three-dimensional object recognition using efficient indexing:Part I-bayesian indexing)

  • 이준호
    • 전자공학회논문지C
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    • 제34C권10호
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    • pp.67-75
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    • 1997
  • A design for a system to perform rapid recognition of three dimensional objects is presented, focusing on efficient indexing. In order to retrieve the best matched models without exploring all possible object matches, we have employed a bayesian framework. A decision-theoretic measure of the discriminatory power of a feature for a model object is defined in terms of posterior probability. Detectability of a featrue defined as a function of the feature itselt, viewpoint, sensor charcteristics, nd the feature detection algorithm(s) is also considered in the computation of discribminatory power. In order to speed up the indexing or selection of correct objects, we generate and verify the object hypotheses for rfeatures detected in a scene in the order of the discriminatory power of these features for model objects.

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Face Recognition Based on PCA on Wavelet Subband of Average-Half-Face

  • Satone, M.P.;Kharate, G.K.
    • Journal of Information Processing Systems
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    • 제8권3호
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    • pp.483-494
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    • 2012
  • Many recent events, such as terrorist attacks, exposed defects in most sophisticated security systems. Therefore, it is necessary to improve security data systems based on the body or behavioral characteristics, often called biometrics. Together with the growing interest in the development of human and computer interface and biometric identification, human face recognition has become an active research area. Face recognition appears to offer several advantages over other biometric methods. Nowadays, Principal Component Analysis (PCA) has been widely adopted for the face recognition algorithm. Yet still, PCA has limitations such as poor discriminatory power and large computational load. This paper proposes a novel algorithm for face recognition using a mid band frequency component of partial information which is used for PCA representation. Because the human face has even symmetry, half of a face is sufficient for face recognition. This partial information saves storage and computation time. In comparison with the traditional use of PCA, the proposed method gives better recognition accuracy and discriminatory power. Furthermore, the proposed method reduces the computational load and storage significantly.

Urinary Concentrations of Human Epidydimis Secretory Protein 4 (He4) in The Diagnosis of Ovarian Cancer: A Case-Control Study

  • Macuks, Ronalds;Baidekalna, Ieva;Donina, Simona
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권9호
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    • pp.4695-4698
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    • 2012
  • Objective: To analyze differential diagnostic accuracy of urinary human epidydimis secretory protein 4 (HE4) in patients with ovarian tumors. Materials and methods: In the case-control study 23 patients with ovarian cancer, 37 patients with benign ovarian tumors and 18 women in the control group were included. Serum CA125 values and urinary concentrations of HE4were assessed quantitatively. Urinary creatinine concentrations and glomerular filtration rate were also determined and used to calculate ratios to HE4. Results: Higher urinary HE4 concentrations were observed in patients with late stage ovarian cancer (p=0.001) and also in patients with early stage ovarian cancer when compared to patients with benign ovarian tumors (p=0.044). On analysis where all ovarian cancer patients were included, higher diagnostic accuracy was observed with calculated ratio of HE4 to glomerular filtration rate (GFR) to unchanged urinary HE4 concentrations -AUC 0.861 vs. 0.858. When discriminatory accuracy was calculated for urinary HE4/GFR ratio and unchanged urinary HE4 concentrations, the last demonstrated a higher area under the curve - 0.701 vs. 0.602. The urinary HE4/creatinine ratio had lower discriminatory characteristics than unchanged concentrations of urinary HE4. However, HE4 serum concentration was more accurate for discrimination of patients with benign and malignant ovarian tumors when compared to urinary HE4 and CA125 in sera (AUCs were 0.868 for serum HE4 and 0.856 and 0.653 for urinary HE4 and CA125, respectively). Conclusions: Ovarian cancer patients have higher urinary concentrations of human epidydimis secretory protein 4 than patients with benign ovarian tumors. Urinary HE4 has comparable discriminatory accuracy with serum HE4 for benign and malignant ovarian tumors and can be recommended as a non-invasive ovarian cancer risk assessment method.