• Title/Summary/Keyword: direct determination

Search Result 513, Processing Time 0.024 seconds

Arsenic Exposure and Haematological Derangement in Cervical Cancer Cases in India

  • Kumar, Rahul;Trivedi, Vinita;Murti, Krishna;Dey, Akalanka;Singh, Jitendra Kumar;Nath, A;Das, P
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.15
    • /
    • pp.6397-6400
    • /
    • 2015
  • Cervical cancer is the second most common gynecological malignancy worldwide. According to HPV Information Centre, Spain (Aug'2014), in India approximately 1,22,844 women are diagnosed with the disease every year and of them 67,477 die due to the disease. CaCx is said to be mediated by HPV but recent data published reveal the role of Oxidative Stress in different Cancers. Arsenic is also one of the agents for causing Oxidative Stress. Arsenic has been linked with different types of cancer. Arsenic is considered responsible for generation of free radicals and eventually for apoptosis. Early diagnosis of CaCx is presently a matter of concern and clinical presentation in advanced stages become difficult for complete clinical response. For determination of oxidative stress, Malondialdehyde (MDA) was taken as an identifier and arsenic estimation was performed with the help of Atomic Absorption Spectrometer (AAS). RBC count and Haemoglobin levels were performed according to standard protocol. MDA was in direct proportion with arsenic concentration and inversely proportional to RBC and Haemoglobin in CaCx patients. Arsenic is one of the major causative agents for oxidative stress and hence may be a risk factor leading to cancer including CaCx.

Corrosion-Fatigue Reliability-Based Life Cycle Cost Analysis of High-Speed Railway Steel Bridges (고속철도 강교량의 부식.피로신뢰성 기반 생애주기비용 분석)

  • Jeon, Hong-Min;Sun, Jong-Wan;Cho, Hyo-Nam
    • Proceedings of the KSR Conference
    • /
    • 2007.11a
    • /
    • pp.1132-1140
    • /
    • 2007
  • As it recently appears that Life Cycle Cost Analysis may be considered as new methodology for economic valuation of infrastructure many researches have been made to assess LCC(Life Cycle Cost) of each facility based on a reasonable methods. In general, LCC is composed of construction cost and expected maintenance repair cost. And especially, maintenance repair cost must be estimated to enhance the reliability through systematic and reasonable methods. However in Korea, because high speed railway steel bridges are recently constructed no direct statistical data are available for the account of the maintenance cost and then their maintenance characteristics are not linear yet. Therefore, the approach proposed in the paper utilizes a theoretical determination and degradation of the corrosion and fatigue of the bridges based on Rahgozar et al.(2006)'s model on fatigue notch factor considering into the corrosion to incorporate the corrosion effect into the fatigue strength reduction model. And then, the corresponding probability of failure is calculated in terms of the reliability index using S-N curve to formulate the fatigue limit state. Therefore, this paper proposes the minimum Life Cycle Cost through optimum maintenance plan analysis of high-speed railway steel bridges under construction. Finally, this paper reviews the proposed model in oder to confirm the applicability and feasibility by appling it to high speed railway steel bridges under construction

  • PDF

APPLICATION OF UNCERTAINTY ANALYSIS TO MAAP4 ANALYSES FOR LEVEL 2 PRA PARAMETER IMPORTANCE DETERMINATION

  • Roberts, Kevin;Sanders, Robert
    • Nuclear Engineering and Technology
    • /
    • v.45 no.6
    • /
    • pp.767-790
    • /
    • 2013
  • MAAP4 is a computer code that can simulate the response of a light water reactor power plant during severe accident sequences, including actions taken as part of accident management. The code quantitatively predicts the evolution of a severe accident starting from full power conditions given a set of system faults and initiating events through events such as core melt, reactor vessel failure, and containment failure. Furthermore, models are included in the code to represent the actions that could mitigate the accident by in-vessel cooling, external cooling of the reactor pressure vessel, or cooling the debris in containment. A key element tied to using a code like MAAP4 is an uncertainty analysis. The purpose of this paper is to present a MAAP4 based analysis to examine the sensitivity of a key parameter, in this case hydrogen production, to a set of model parameters that are related to a Level 2 PRA analysis. The Level 2 analysis examines those sequences that result in core melting and subsequent reactor pressure vessel failure and its impact on the containment. This paper identifies individual contributors and MAAP4 model parameters that statistically influence hydrogen production. Hydrogen generation was chosen because of its direct relationship to oxidation. With greater oxidation, more heat is added to the core region and relocation (core slump) should occur faster. This, in theory, would lead to shorter failure times and subsequent "hotter" debris pool on the containment floor.

A Study on the Crustal Structure of South Korea by using Seismic Waves (지진파(地震波)를 이용(利用)한 남한(南韓)의 지각구조(地殼構造) 연구(硏究))

  • Kim, Sang Jo;Kim, So Gu
    • Economic and Environmental Geology
    • /
    • v.16 no.1
    • /
    • pp.51-61
    • /
    • 1983
  • By using local earthquake data, the Korean crust model and travel-time tables were determined. The upper crustal earthquakes (Hongsung event and Ssanggyesa event) were considered as auxiliary information, and the lower crustal earthquakes (Uljin event and Pohang event) played an important role in determining model parameters. The possible existence of Low Velocity Layer (LVL) in the upper mantle was suggested by discrepancy in the arrival times of Sariwon earthquake which occurred below Moho discontinuity. Computer program for the determination of the model parameters was developed in order to screened out the optimum parameters by comparing the travel times of observed data with theoretical ones. We found that the discontinuities of Conrad, Moho, and upper and lower boundaries of LVL have their depth of 15, 32, 55 and 75 Km, respectively. The velocities of P-and S-wave in the layers between those discontinities were found to be (1) 5.98, 3.40 Km/sec (2) 6.38, 3.79 Km/sec (3) 7.95, 4.58 Km/sec (4) unknown (5) 8.73, 5.05 Km/sec, respectively from the top layer. Travel-time tables were also computed for the inter-local earthquakes which have their direct wave paths above the LVL.

  • PDF

Identification of Nursing Activities for Determination of Nursing Cost (간호수가 산정을 위한 간호행위의 규명 연구)

  • 박정호;황보수자;이은숙
    • Journal of Korean Academy of Nursing
    • /
    • v.22 no.2
    • /
    • pp.185-206
    • /
    • 1992
  • In this study nursing activities were examined to determine the nursing cost. A professional nursing group developed a tool for the investigation. 128 nursing activities were identified by the tool in 16 nursing care areas as referenced in the literature. Each activity was examined for four essential factors to define nursing cost ; time consumed for the care, level of professional skill, degree of independency and performer of the care. The activity was rated by a five point Likert scale. This investigation was conducted with the nursing staffing working in the 21 university hospitals in Korea and having more than four years experience especially in medical or surgical wards. The participating nursing staff were screened on the basic of the recommendation of the nursing director. The data were gathered from June 12th to August 12th, 1989. All the data were analyzed for mean, standard deviation, percent, and correlation coefficients between items. The results are summarized as follows : 1. Direct nursing care was classified into 16 large areas and 128 small activities. 2. No significant correlation was found between the study items of each activity. 3. Among 128 nursing activities, Those performed less than 50% of the time by a nurse were excluded from the nursing cost. Also excluded activities which were given less than 9 marks in all three items, time consumed, level of professional skill, and degree of independency. As a result, 83 activities in 14 nursing care areas were selected for the proposal to estimate nursing cost.

  • PDF

Speed Control of PMSM using DTC-PWM Approach (DTC-PWM 방식에 의한 PMSM의 속도 제어 기법)

  • Lee, Dong-Hee;Choo, Young-Bae
    • The Transactions of the Korean Institute of Power Electronics
    • /
    • v.14 no.4
    • /
    • pp.268-277
    • /
    • 2009
  • This paper presents an DTC-PWM (Direct Torque Control-Pulse Width Modulation) of PMSM (Permanent Magnet Synchronous Motor). The proposed DTC-PWM method combines a conventional DTC and PWM approach for switching signal generation. The actual torque is estimated by the torque estimator in conventional method, but the switching signal is generated by PWM method according to the switching rules and torque error. A effective voltage vector and zero vector are used to generate the switching signals and asymmetric switching method is applied. A simple calculation of PWM without any complex determination of space vector can assure the constant switching frequency with an constant torque and flux. The proposed torque control scheme for PMSM is verified by experimental results.

Control Effects of an Antibiotic Produced by Streptomyces sp. B25 on Tobacco Mosaic Virus and Determination of Its Molecular Structure

  • Yeo, Woon-Hyung;Kim, Young-Ho;Kim, Young-Sook;Kim, Sang-Seock;Chae, Soon-Yong
    • Journal of the Korean Society of Tobacco Science
    • /
    • v.20 no.2
    • /
    • pp.172-177
    • /
    • 1998
  • The culture filtrate of Streptomyces sp. B25, which was identified in this experiment, was tested for the control of tobacco mosaic virus (TMV) with the susceptible tobacco cultivar, NC 82, under the field conditions following the preliminary examination of its characters for TMV control. Control efficacy of the culture filtrate against TMV infection continued over 50% up to 6 days after treatment, and its systemic effect was about 30% of the direct effect. In field conditions control efficacy of the culture filtrate against TMV infection was 95.3 % at 2 weeks after TMV inoculation, and decreased to 58.3 % at 3 weeks after inoculation. Five fold-dilution of the culture filtrate showed about half of the control efficacy by the stock culture filtrate. Analysis of the antibiotic material responsible for the inhibition of TMV infection through nuclear magnetic resonance experiments revealed that the antibiotic is antimycin $A_1$, which is firstly reported as an anti-phytoviral antibiotic in this experiment.

  • PDF

Dynamic Shear Modulus of Crushable Sand (잘 부서지는 모래의 동적전단탄성계수)

  • 윤여원
    • Geotechnical Engineering
    • /
    • v.8 no.4
    • /
    • pp.67-80
    • /
    • 1992
  • In the analysis of dynamic problem, determination of mazimun shear modulus is essential for the estimation of shear stress at any strain level. Although many models for silica sands were presented, the direct accomodation of those models to crushable sand would be difficult because of crushability during torsion. In this research dynamic behaviour of tested sand is presented. The shear modulus of loose crushable sand shows similar results to silica sand. However, as the density of crushable sand increases the shear modulus decreases because of crushability by increasing surface contact area. And modulus number is expressed in terms of state parameter by Been and Jefferies (1965).

  • PDF

A Study on Numerical Optimization Method for Aerodynamic Design (공력설계를 위한 수치최적설계기법의 연구)

  • Jin, Xue-Song;Choi, Jae-Ho;Kim, Kwang-Yong
    • The KSFM Journal of Fluid Machinery
    • /
    • v.2 no.1 s.2
    • /
    • pp.29-34
    • /
    • 1999
  • To develop the efficient numerical optimization method for the design of an airfoil, an evaluation of various methods coupled with two-dimensional Naviev-Stokes analysis is presented. Simplex method and Hook-Jeeves method we used as direct search methods, and steepest descent method, conjugate gradient method and DFP method are used as indirect search methods and are tested to determine the search direction. To determine the moving distance, the golden section method and cubic interpolation method are tested. The finite volume method is used to discretize two-dimensional Navier-Stokes equations, and SIMPLEC algorithm is used for a velocity-pressure correction method. For the optimal design of two-dimensional airfoil, maximum thickness, maximum ordinate of camber line and chordwise position of maximum ordinate are chosen as design variables, and the ratio of drag coefficient to lift coefficient is selected as an objective function. From the results, it is found that conjugate gradient method and cubic interpolation method are the most efficient for the determination of search direction and the moving distance, respectively.

  • PDF

Determination of Silver with Mercaptans (I). Amperometric Titration of Silver with 2,5-Dimercapto-1,3,4-Thiadiazole (Mercapto 화합물에 의한 은의 정량 (제1보) 2,5-Dimercapto-1,3,4-Thiadiazol에 의한 은의 전류 적정)

  • Young Gu Ha;Q. Won Choi
    • Journal of the Korean Chemical Society
    • /
    • v.17 no.2
    • /
    • pp.126-129
    • /
    • 1973
  • An amperometric method has been developed for the titration of silver with 2,5-dimercapto-1,3,4,-thiadiazole in ammonical solution (1N) using rotating platinum electrode as an indicator electrode and the mercury-mercury (II) iodide as reference electrode. Direct titration of milligram amount of silver (0.05-1.0mg) is possible in the presence of a number of foreign ions in ammonical solution containing ethylenediaminetetraacetic acid as masking agent under atmosphere. The interfering elements are gold and platinum. The milligram amount of silver can be determined by the proposed method within an error ${\pm}3{\%}$.

  • PDF