• Title/Summary/Keyword: direct determination

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Quantitative Approaches for the Determination of Volatile Organic Compounds (VOC) and Its Performance Assessment in Terms of Solvent Types and the Related Matrix Effects

  • Ullah, Md. Ahsan;Kim, Ki-Hyun;Szulejko, Jan E.;Choi, Dal Woong
    • Asian Journal of Atmospheric Environment
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    • v.11 no.1
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    • pp.1-14
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    • 2017
  • For the quantitative analysis of volatile organic compounds (VOC), the use of a proper solvent is crucial to reduce the chance of biased results or effect of interference either in direct analysis by a gas chromatograph (GC) or with thermal desorption analysis due to matrix effects, e.g., the existence of a broad solvent peak tailing that overlaps early eluters. In this work, the relative performance of different solvents has been evaluated using standards containing 19 VOCs in three different solvents (methanol, pentane, and hexane). Comparison of the response factor of the detected VOCs confirms their means for methanol and hexane higher than that of pentane by 84% and 27%, respectively. In light of the solvent vapor pressure at the initial GC column temperature ($35^{\circ}C$), the enhanced sensitivity in methanol suggests the potential role of solvent vapor expansion in the hot injector (split ON) which leads to solvent trapping on the column. In contrast, if the recurrent relationships between homologues were evaluated using an effective carbon number (ECN) additivity approach, the comparability assessed in terms of percent difference improved on the order of methanol (26.5%), hexane (6.73%), and pentane (5.24%). As such, the relative performance of GC can be affected considerably in the direct injection-based analysis of VOC due to the selection of solvent.

Studies on development of ELISA Kits for T-2 toxin (T-2 독소의 측정을 위한 ELISA Kits의 개발에 관한 연구)

  • Yoon, Hwa-joong;Kim, Taejong;Lee, Sung-yun
    • Korean Journal of Veterinary Research
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    • v.37 no.3
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    • pp.613-618
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    • 1997
  • Direct competitive enzyme linked immunosorbent assay(ELISA) with monoclonal antibodies have been studied for quantitative determination of T-2 toxin from the mold corn. The T-2HS, T-2HS-BSA, T-2HS-HRP and monoclonal antibodies against T-2 toxin produced in the studies were qualified for quantitative ELISA test of T-2 toxin. The mean recovery rate from ground com spiked T-2 toxin was 83%. The meaning range of the T-2 test was 60ng to $2{\mu}g$. According to the recovery results with the com spiked T-2, the tests proved to be suitable in the screening of the moldy feed samples for the presence of T-2 toxin and will be able to become the basis of the ELISA test for the quantitative screening kits of T-2 toxin.

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Direct Determination of Tellurium in Simulated Nuclear Spent Fuels by Hydride Generation-Inductively Coupled Plasma Atomic Emission Spectrometry (수소화물 생성-유도결합플라스마 원자방출분광법을 이용한 모의사용후 핵연료 중의 텔루르 분석)

  • Choi, Kwang Soon;Lee, Chang Heon;Han, Sun Ho;Joe, Kih Soo;Kim, Won Ho
    • Analytical Science and Technology
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    • v.13 no.6
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    • pp.781-788
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    • 2000
  • Tellurium in simulated nuclear spent fuels (SIMFUEL) has been determined by hydride generation-inductively coupled plasma atomic emission spectrometry (HG-ICP-AES). Parameters such as concentrations of HCl and $NaBH_4$, flow rate of HCl and $NaBH_4$ were optimized and then the effects of U, Mo, Pd, Rh and Ru on the Te intensity were investigated. A thiourea as a masking agent was used to eliminate or minimize such interferences specially caused by palladium. Tellurium was measured by HG-ICP-AES and ICP-MS after separation of tellurium from SIMFUEL with cation exchange chromatography. The relative deviation between direct measurement and separation method was less than 6% based on the data by ICP-MS.

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Theoretical Growth Equations and Their Application with a Direct Search Method (직접탐색법(直接探索法)을 이용한 이론적(理論的) 생장함수(生長函數)의 적용(適用))

  • Seo, Ok-ha
    • Journal of Forest and Environmental Science
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    • v.8 no.1
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    • pp.35-49
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    • 1992
  • Three theoretical growth equations, i.e., the Mitscherlich, the Gompertz, and the Logistic equation, were applied to the radical stem growth of 50 jack pines (Pinus banksiana Lamb.). For the determination of the parameters in these equations, NELDER-MEAD's method was used, which is one of the direct-search methods of optimization. It has been known to be very convenient in dealing with the issues related to optimization, specifically where the number of parameters are less than 6. It was found that although all the equations did not appropriately work as expected, the Mitscherlich equation revealed the least discrapancy from the obsered value among three. Using these equations and the first certain period data, i. e., 35, 55, 75 years, the predection of radius of age 95 was investigated. Comparing to the observed value, the most valid equation was the Mitscherlich, and the next were the Gompertz and the Logistic, in order.

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A Structural Equation Model of Health-Related Quality of Life among Older Women Following Bilateral Total Knee Replacement (양측 슬관절 전치환술 여성노인의 건강관련 삶의 질 구조모형)

  • Lee, Hyun Ok;Yoo, Jae Soon
    • Journal of Korean Academy of Nursing
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    • v.50 no.4
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    • pp.554-570
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    • 2020
  • Purpose: This study aimed to develop and test a structural equation model of health-related quality of life among older women following bilateral total knee replacement based on a literature review and Wilson and Cleary's model of health-related quality of life. Methods: One hundred ninety three women who were diagnosed with osteoarthritis, were older than 65 years, and were between 13 weeks and 12 months of having a bilateral total knee replacement were recruited from an outpatient clinic. Data were collected from July 2017 to April 2018 using a structured questionnaire and medical records. Data were analyzed using SPSS/WIN 22.0, AMOS 22.0, and Smart PLS 3.2.4. Results: The fitness of the hypothetical model was good, with coefficients of determination (R2) ranging between .28 and .75 and predictive relevance (Q2) between .26 and .73. The standardized root mean square residual of the model fit indices for the hypothetical model was .04; which explained 64.2% of physical and 62.5% of mental health-related quality of life. Self-efficacy, symptom status, functional status, and general health perceptions had a significant direct effect on physical health-related quality of life, while social support, symptom status, and general health perceptions had a significant direct effect on participants' mental-health-related quality of life. Conclusion: To improve the physical and mental quality of life of older women who receive bilateral knee replacement, nursing-based intervention strategies that reduce symptoms, improve functional status, and increase health perceptions, self-efficacy, and social support are needed. The most important factor is the symptom status.

Non-linear time-dependent post-elastic analysis of suspended cable considering creep effect

  • Kmet, S.;Tomko, M.;Brda, J.
    • Structural Engineering and Mechanics
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    • v.22 no.2
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    • pp.197-222
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    • 2006
  • In this paper, the non-linear time-dependent closed-form, discrete and combined solutions for the post-elastic response of a geometrically and physically non-linear suspended cable to a uniformly distributed load considering the creep effects, are presented. The time-dependent closed-form method for the particularly straightforward determination of a vertical uniformly distributed load applied over the entire span of a cable and the accompanying deflection at time t corresponding to the elastic limit and/or to the elastic region, post-elastic and failure range of a suspended cable is described. The actual stress-strain properties of steel cables as well as creep of cables and their rheological characteristics are considered. In this solution, applying the Irvine's theory, the direct use of experimental data, such as the actual stress-strain and strain-time properties of high-strength steel cables, is implemented. The results obtained by the closed-form solution, i.e., a load corresponding to the elastic limit, post-elastic and failure range at time t, enable the direct use in the discrete non-linear time-dependent post-elastic analysis of a suspended cable. This initial value of load is necessary for the non-linear time-dependent elastic and post-elastic discrete analysis, concerning incremental and iterative solution strategies with tangent modulus concept. At each time step, the suspended cable is analyzed under the applied load and imposed deformations originated due to creep. This combined time-dependent approach, based on the closed-form solution and on the FEM, allows a prediction of the required load that occurs in the post-elastic region. The application of the described methods and derived equations is illustrated by numerical examples.

Modified Pharmacokinetic/Pharmacodynamic model for electrically activated silver-titanium implant system

  • Tan, Zhuo;Orndorff, Paul E.;Shirwaiker, Rohan A.
    • Biomaterials and Biomechanics in Bioengineering
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    • v.2 no.3
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    • pp.127-141
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    • 2015
  • Silver-based systems activated by low intensity direct current continue to be investigated as an alternative antimicrobial for infection prophylaxis and treatment. However there has been limited research on the quantitative characterization of the antimicrobial efficacy of such systems. The objective of this study was to develop a semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) model providing the quantitative relationship between the critical system parameters and the degree of antimicrobial efficacy. First, time-kill curves were experimentally established for a strain of Staphylococcus aureus in a nutrientrich fluid environment over 48 hours. Based on these curves, a modified PK/PD model was developed with two components: a growing silver-susceptible bacterial population and a depreciating bactericidal process. The test of goodness-of-fit showed that the model was robust and had good predictability ($R^2>0.7$). The model demonstrated that the current intensity was positively correlated to the initial killing rate and the bactericidal fatigue rate of the system while the anode surface area was negatively correlated to the fatigue rate. The model also allowed the determination of the effective range of these two parameters within which the system has significant antimicrobial efficacy. In conclusion, the modified PK/PD model successfully described bacterial growth and killing kinetics when the bacteria were exposed to the electrically activated silver-titanium implant system. This modeling approach as well as the model itself can also potentially contribute to the development of optimal design strategies for other similar antimicrobial systems.

A Comparison of PM10 Exposure Characteristics of Swine Farmers by Body Parts using Direct-reading Instrument (직독식 기기를 이용한 양돈작업자의 신체부위별 PM10 노출 특성 비교 연구)

  • Sin, Sojung;Kim, Hyocher;Kim, Kyung-ran;Seo, Mintae;Park, Sooin;Kim, Kyungmin;Kim, Kyungsu
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.29 no.2
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    • pp.159-166
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    • 2019
  • Objectives: The purpose of this study was to evaluate the personal exposure to $PM_{10}$ by body parts for the development of dust monitoring wearable device for swine farmers. Methods: Tasks were classified by using motion pictures taken by action cameras attached to swine farmers. Concentrations of $PM_{10}$ were measured by attaching direct-reading instruments at the head, neck and waist of worker. Differences of $PM_{10}$ exposure between body parts were analyzed with linear regression. Results: We identified three tasks(vaccination, moving pigs, and manure treatment). $PM_{10}$ concentration during vaccination was the highest among the tasks, and the body part showing the highest concentration of $PM_{10}$ was the waist regardless of task. In all tasks, the closer distance between the body parts, the higher were the R-squared values(vaccination 0.4221, moving pigs 0.6990, and manure treatment 0.2164). Conclusions: We presumed that $PM_{10}$ concentrations were affected by the parts of the body in which they were measured. In order to develop swine farmer's wearable device for monitoring dust concentration in air, the determination of the positions of monitoring sensor to ensure accurate measurement is essential. Considering the results of this study, wearable sensor should be positioned at the waist.

Determination of Cost and Measurement of nursing Care Hours for Hospice Patients Hospitalized in one University Hospital (일 대학병원 호스피스 병동 입원 환자의 간호활동시간 측정과 원가산정)

  • Kim, Kyeong-Uoon
    • Journal of Korean Academy of Nursing Administration
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    • v.6 no.3
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    • pp.389-404
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    • 2000
  • This study was designed to determine the cost and measurement of nursing care hours for hospice patients hostpitalized in one university hospital. 314 inpatients in the hospice unit 11 nursing manpower were enrolled. Study was taken place in C University Hospital from 8th to 28th, Nov, 1999. Researcher and investigator did pilot study for selecting compatible hospice patient classification indicators. After modifying patient classification indicators and nursing care details for general ward, approved of content validity by specialist. Using hospice patient classification indicators and per 5 min continuing observation method, researcher and investigator recorded direct nursing care hours, indirect nursing care hours, and personnel time on hospice nursing care hours, and personnel time on hospice nursing care activities sheet. All of the patients were classified into Class I(mildly ill), Class II (moderately ill), Class III (acutely ill), and Class IV (critically ill) by patient classification system (PCS) which had been carefully developed to be suitable for the Korean hospice ward. And then the elements of the nursing care cost was investigated. Based on the data from an accounting section (Riccolo, 1988), nursing care hours per patient per day in each class and nursing care cost per patient per hour were multiplied. And then the mean of the nursing care cost per patient per day in each class was calculated. Using SAS, The number of patients in class and nursing activities in duty for nursing care hours were calculated the percent, the mean, the standard deviation respectively. According to the ANOVA and the $Scheff{\'{e}$ test, direct nursing care hours per patient per day for the each class were analyzed. The results of this study were summarized as follows : 1. Distribution of patient class : class IN(33.5%) was the largest class the rest were class II(26.1%) class III(22.6%), class I(17.8%). Nursing care requirements of the inpatients in hospice ward were greater than that of the inpatients in general ward. 2. Direct nursing care activities : Measurement ${\cdot}$ observation 41.7%, medication 16.6%, exercise ${\cdot}$ safety 12.5%, education ${\cdot}$ communication 7.2% etc. The mean hours of direct nursing care per patient per day per duty were needed ; 69.3 min for day duty, 64.7 min for evening duty, 88.2 min for night duty, 38.7 min for shift duty. The mean hours of direct nursing care of night duty was longer than that of the other duty. Direct nursing care hours per patient per day in each class were needed ; 3.1 hrs for class I, 3.9 hrs for class II, 4.7 hrs for class III, and 5.2 hrs for class IV. The mean hours of direct nursing care per patient per day without the PCS was 4.1 hours. The mean hours of direct nursing care per patient per day in class was increased significantly according to increasing nursing care requirements of the inpatients(F=49.04, p=.0001). The each class was significantly different(p<0.05). The mean hours of direct nursing care of several direct nursing care activities in each class were increased according to increasing nursing care requirements of the inpatients(p<0.05) ; class III and class IV for medication and education ${\cdot}$ communication, class I, class III and class IV for measurement ${\cdot}$ observation, class I, class II and class IV for elimination ${\cdot}$ irrigation, all of class for exercise ${\cdot}$ safety. 3. Indirect nursing care activities and personnel time : Recognization 24.2%, house keeping activity 22.7%, charting 17.2%, personnel time 11.8% etc. The mean hours of indirect nursing care and personnel time per nursing manpower was 4.7 hrs. The mean hours of indirect nursing care and personnel time per duty were 294.8 min for day duty, 212.3 min for evening duty, 387.9 min for night duty, 143.3 min for shift duty. The mean of indirect nursing care hours and personnel time of night duty was longer than that of the other duty. 4. The mean hours of indirect nursing care and personnel time per patient per day was 2.5 hrs. 5. The mean hours of nursing care per patient per day in each class were class I 5.6 hrs, class II 6.4 hrs, class III 7.2 hrs, class IV 7.7 hrs. 6. The elements of the nursing care cost were composed of 2,212 won for direct nursing care cost, 267 won for direct material cost and 307 won for indirect cost. Sum of the elements of the nursing care cost was 2,786 won. 7. The mean cost of the nursing care per patient per day in each class were 15,601.6 won for class I, 17,830.4 won for class II, 20,259.2 won for class III, 21,452.2 won for class IV. As above, using modified hospice patient classification indicators and nursing care activity details, many critical ill patients were hospitalized in the hospice unit and it reflected that the more nursing care requirements of the patients, the more direct nursing care hours. Emotional ${\cdot}$ spiritual care, pain ${\cdot}$ symptom control, terminal care, education ${\cdot}$ communication, narcotics management and delivery, attending funeral ceremony, the major nursing care activities, were also the independent hospice service. But it is not compensated by the present medical insurance system. Exercise ${\cdot}$ safety, elimination ${\cdot}$ irrigation needed more nursing care hours as equal to that of intensive care units. The present nursing management fee in the medical insurance system compensated only a part of nursing car service in hospice unit, which rewarded lower cost that that of nursing care.

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Determination of Safe Cropping Season in Direct- Seeding of Rice on Flooded Paddy by Using Effective Temperatures in Agroclimatic Zones (농업기후지대별 작물생육 유효기온 출현특성에 따른 벼 담수직파 안전작기 설정)

  • Shim Kyo-Moon;Lee Jeong-Taek;Yun Seong-Ho;Choi Don-Hyang
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.1 no.1
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    • pp.72-80
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    • 1999
  • The study was conducted to establish the safe cropping season for direct- seeding on flooded paddy by the analysis of meteorological data(l973~1992, 20 years) from Korea Meteorological Administration. The critical date for early seeding(CDES) at direct- seeding culture on flooded paddy was decided by the appearance date of daily mean air temperature(DMAT) of 15$^{\circ}C$. The optimum heading date(OHD) was the first day when 22$^{\circ}C$ of daily mean air temperature could be kept for 40 days of ripening period after heading, and the critical date of late heading for safe ripening(CDHR) was the last day when 19$^{\circ}C$ of daily mean air temperature could be kept for 40 days after heading. The optimum seeding date(OSD) and the critical date for late seeding(CDLS) could be decided by the accumulated temperature from OHD and CDHR to the appearance dates of necessary temperatures for early, intermediate, and intermediately late maturing varieties. This results can be used for the determination of the safe cropping season of direct-seeding on flooded paddy in each agroclimatic zone. For instance, the OSD appearance date for early maturing variety in Suwon region appeared to be May 11~20 and the CDLS appearance date was May 31~June 7.

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