• Title/Summary/Keyword: diffusion mechanism

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Complete Recovery of Perfusion Abnormalities in a Cardiac Arrest Patient Treated with Hypothermia: Results of Cerebral Perfusion MR Imaging

  • Kim, Min Jeong;Park, Yae Won;Lim, Soo Mee
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.1
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    • pp.56-60
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    • 2018
  • Therapeutic hypothermia in cardiac arrest patients is associated with favorable outcomes mediated via neuroprotective mechanisms. We report a rare case of a 32-year-old male who demonstrated complete recovery of signal changes on perfusion-weighted imaging after therapeutic hypothermia due to cardiac arrest. Brain MRI with perfusion-weighted imaging, performed three days after ending the hypothermia therapy, showed a marked decrease in relative cerebral blood flow (rCBF) and delay in mean transit time (MTT) in the bilateral basal ganglia, thalami, brain stem, cerebellum, occipitoparietal cortex, and frontotemporal cortex. However, no cerebral ischemia was not noted on diffusion-weighted imaging (DWI) or fluid-attenuated inversion recovery (FLAIR) sequences. A follow-up brain MRI after one week showed complete resolution of the perfusion deficit and the patient was discharged without any neurologic sequelae. The mechanism and interpretation of the perfusion changes in cardiac arrest patients treated with therapeutic hypothermia are discussed.

A Flame Study of Soot Deposition and Reentrainment in Application to Control of Diesel Soot Emission (디젤엔진 관련 Soot 부착 및 재유입에 관한 화염에서의 연구)

  • Kim, Seong-Geun;Park, Jong-In
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.20 no.8
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    • pp.2626-2636
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    • 1996
  • A study of soot deposition and reentrainment was carried out both theoretically and experimentally to understand behavior of soot formed by incomplete combustion in a diesel engine. Theoretically, soot deposition on engine cylinder wall and/or piston head was studied with a stagnation point flow approximation. Soot reentrainment occurred upon exhaust gas blowdown was also studied by assuming a long-normal shear velocity distribution. Experimentally, a LPG$O_2/N_2$ flame impinging on a disk, produced by a concentric tubular burner, was chosen as deposition configuration and a shear flow unit with compressed air was installed for the study of reentrainment. For selected flame configuration, soot deposition measurements were conducted and showed that the dominant deposition mechanism was thermophoresis. Distributions of gas temperature and soot number density were estimated by combining data obtained by a B-type thermocouple with a thermophoretic transport theory. Disk temperature distributions were directly measured using a K-type thermocouple. Soot size and morphology were estimated from a TEM photograph. Ratios of soot deposit to reentrained amount were measured for a wide range of shear flow velocities, which showed that the reentrainment model was reasonable.

Hydroxyapatite-Zirconia Composite Thin Films Showing Improved Mechanical Properties and Bioactivity

  • Kim, Min-Seok;Ryu, Jae-Jun;Sung, Yun-Mo
    • Korean Journal of Materials Research
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    • v.19 no.2
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    • pp.85-89
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    • 2009
  • Nano-crystalline hydroxyapatite (HAp) films were formed at the Ti surface by a single-step microarc oxidation (MAO), and HAp-zirconia composite (HZC) films were obtained by subsequent chemical vapor deposition (CVD) of zirconia onto the HAp. Through the CVD process, zero- and one-dimensional zirconia nanostructures having tetragonal crystallinity (t-ZrO2) were uniformly distributed and well incorporated into the HAp crystal matrix to form nanoscale composites. In particular, (t-$ZrO_2$) was synthesized at a very low temperature. The HZC films did not show secondary phases such as tricalcium phosphate (TCP) and tetracalcium phosphate (TTCP) at relatively high temperatures. The most likely mechanism for the formation of the t-$ZrO_2$ and the pure HAp at the low processing temperature was proposed to be the diffusion of $Ca^{2+}$ ions. The HZC films showed increasing micro-Vickers hardness values with increases in the t-$ZrO_2$ content. The morphological features and phase compositions of the HZC films showed strong dependence on the time and temperature of the CVD process. Furthermore, they showed enhanced cell proliferation compared to the $TiO_2$ and HAp films most likely due to the surface structure change.

Design and Implementation of Flooding based Energy-Efficiency Routing Protocol for Wireless Sensor Network (무선 센서네트워크에서 에너지 효율을 고려한 단층기반 라우팅 프로토콜의 설계와 구현)

  • Lee, Myung-Sub;Park, Chang-Hyeon
    • The KIPS Transactions:PartC
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    • v.17C no.4
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    • pp.371-378
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    • 2010
  • In this paper, we propose a new energy-efficient routing algorithm for sensor networks that selects a least energy consuming path among the paths formed by node with highest remaining energy and provides long network lifetime and uniform energy consumption by nodes. The pair distribution of the energy consumption over all the possible routes to the base station is one of the design objectives. Also, an alternate route search mechanism is proposed to cope with the situation in which no routing information is available due to lack of remaining energy of the neighboring nodes. Simulation results show that our algorithm extends the network lifetime and enhances the network reliability by maintaining relatively uniform remaining energy distribution among sensor nodes.

The Microsponge Delivery System of Itraconazole: Preparation, Characterization and Release Studies (이트라코나졸 마이크로스폰지의 약물 전달 시스템: 제조, 특성 및 방출 연구)

  • Cho, Young-Ho;Lee, Jong-Hwa;Kim, Hak-Hyung;Lee, Gye-Won
    • KSBB Journal
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    • v.26 no.3
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    • pp.217-222
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    • 2011
  • Itraconazole is a triazole antifungal agent to inhibit most fungal pathogens. To improve the oral absorption and dissolution of poorly water-soluble itraconazole, microsponge system composed of $Eudragit^{(R)}$ E100 and polyvinyl alcohol(PVA) formulated by quasi-emulsion solvent diffusion method, and its physicochemical properties and pharmacokinetic parameters of itraconazole were studied. The microsponge of itraconazole were discrete free flowing micro sized particles with perforated orange peel like morphology as visualized by scanning electron microscope (SEM). Results showed that the drug loading efficiency, production yield, and particle size of itraconazole microsponge were affected by drug to polymer ratio, the volume of internal phase containing methylene chloride, stirring rate and the concentration of PVA used. Also, the results showed that the dissolution rate of itraconazole from the microsponges was affected by drug to polymer ratio. In other words, the release rate of itraconazole from microsponges was increased from at least 27.43% to 64.72% after 2 h. The kinetics of dissolution mechanism showed that the dissolution data followed Korsmeyer-Peppas model. Therefore, these results suggest that microsponge system can be useful for the oral delivery of itraconazole by manipulating the release profile.

On the Reaction Kinetics of GaN Particles Formation from GaOOH (GaOOH로부터 GaN 분말 형성의 반응역학에 관하여)

  • Lee Jaebum;Kim Seontai
    • Korean Journal of Materials Research
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    • v.15 no.5
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    • pp.348-352
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    • 2005
  • Gallium oxyhydroxide (GaOOH) powders were heat-treated in a flowing ammonia gas to form GaN, and the reaction kinetics of the oxide to nitride was quantitatively determined by X-ray diffraction analysis. GaOOH turned into intermediate mixed phases of $\alpha-\;and\;\beta-Ga_2O_3$, and then single phase of GaN. The reaction time for full conversion $(t_c)$ decreased as the temperature increased. There were two-types of rapid reaction processes with the reaction temperature in the initial stage of nitridation at below $t_c$, and a relatively slow processes followed over $t_c$ does not depends on temperatures. The nitridation process was found to be limited by the rate of an interfacial reaction with the reaction order n value of 1 at $800^{\circ}C$ and by the diffusion-limited reaction with the n of 2 at above $1000^{\circ}C$, respectively, at below $t_c$. The activation energy for the reaction was calculated to be 1.84 eV in the temperature of below $830^{\circ}C$, and decreased to 0.38 eV above $830^{\circ}C$. From the comparative analysis of data, it strongly suggest the rate-controlling step changed from chemical reaction to mass transport above $830^{\circ}C$.

Utilization of Cotton Stalks-Biomass Waste in the Production of Carbon Adsorbents by KOH Activation for Removal of Dye-Contaminated Water

  • Fathy, Nady A.;Girgis, Badie S.;Khalil, Lila B.;Farah, Joseph Y.
    • Carbon letters
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    • v.11 no.3
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    • pp.224-234
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    • 2010
  • Four activated carbons were produced by two-stage process as followings; semi-carbonization of indigenous biomass waste, i.e. cotton stalks, followed by chemical activation with KOH under various activation temperatures and chemical ratios of KOH to semi-carbonized cotton stalks (CCS). The surface area, total pore volume and average pore diameter were evaluated by $N_2$-adsorption at 77 K. The surface morphology and oxygen functional groups were determined by SEM and FTIR, respectively. Batch equilibrium and kinetic studies were carried out by using a basic dye, methylene blue as a probe molecule to evaluate the adsorption capacity and mechanism over the produced carbons. The obtained activated carbon (CCS-1K800) exhibited highly microporous structure with high surface area of 950 $m^2/g$, total pore volume of 0.423 $cm^3/g$ and average pore diameter of 17.8 ${\AA}$. The isotherm data fitted well to the Langmuir isotherm with monolayer adsorption capacity of 222 mg/g for CCS-1K800. The kinetic data obtained at different concentrations were analyzed using a pseudo-first-order, pseudo-second-order and intraparticle diffusion equations. The pseudo-second-order model fitted better for kinetic removal of MB dye. The results indicate that such laboratory carbons could be employed as low cost alternative to commercial carbons in wastewater treatment.

A Flexible Feature Matching for Automatic Facial Feature Points Detection (얼굴 특징점 자동 검출을 위한 탄력적 특징 정합)

  • Hwang, Suen-Ki;Bae, Cheol-Soo
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.3 no.2
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    • pp.12-17
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    • 2010
  • An automatic facial feature points(FFPs) detection system is proposed. A face is represented as a graph where the nodes are placed at facial feature points(FFPs) labeled by their Gabor features and the edges are describes their spatial relations. An innovative flexible feature matching is proposed to perform features correspondence between models and the input image. This matching model works likes random diffusion process in the image space by employing the locally competitive and globally corporative mechanism. The system works nicely on the face images under complicated background, pose variations and distorted by facial accessories. We demonstrate the benefits of our approach by its implementation on the system.

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A flexible Feature Matching for Automatic Face and Facial Feature Points Detection (얼굴과 얼굴 특징점 자동 검출을 위한 탄력적 특징 정합)

  • 박호식;배철수
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.4
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    • pp.705-711
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    • 2003
  • An automatic face and facial feature points(FFPs) detection system is proposed. A face is represented as a graph where the nodes are placed at facial feature points(FFPs) labeled by their Gabor features and the edges are describes their spatial relations. An innovative flexible feature matching is proposed to perform features correspondence between models and the input image. This matching model works likes random diffusion process in !be image space by employing the locally competitive and globally corporative mechanism. The system works nicely on the face images under complicated background, pose variations and distorted by facial accessories. We demonstrate the benefits of our approach by its implementation on the face identification system.

Simulation of Design Factor Effects on Performance of Vacuum System (진공시스템 성능에 대한 설계인자 영향 전산모사)

  • Kim, Hyung-Taek;Jeong, Kwang-Pil
    • Journal of the Korean Vacuum Society
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    • v.16 no.6
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    • pp.405-413
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    • 2007
  • Effect of design factors on the performance of vacuum system was simulated for optimum design of system. In this investigation, the feasibility of modelling mechanism for $VacSim^{Multi}$ simulator was proposed. Simulation results of pumping design factor showed the possibilities of simulation fore-study for the detailed design factors. Simulation of roughing pump presented the expected pumping behaviors based on the specifications of commercial pump. Application of booster pump exhibited the high pumping efficiency for middle vacuum range. Combinations of optimum backing pump for diffusion and turbo vacuum system were obtained. And, the characteristics of process application of both systems were also acquired.