• Structural Engineering and Mechanics
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• v.50 no.5
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• pp.697-708
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• 2014

The intentional buckling design of micro-films has various potential applications in engineering. The buckling amplitude and critical strain of micro-films are the crucial parameters for the buckling design. In the reported studies, the film parameters were regarded as deterministic. However, the geometrical and physical parameters uncertainty of micro-films due to manufacturing becomes prominent and needs to be considered. In the present paper, the probabilistic nonlinear buckling analysis of micro-films with uncertain parameters is proposed for design accuracy and reliability. The nonlinear differential equation and its asymptotic solution for the buckling micro-film with nominal parameters are firstly established. The mean values, standard deviations and variation coefficients of the buckling amplitude and critical strain are calculated by using the probability densities of uncertain parameters such as the film span length, thickness, elastic modulus and compressive force, to reveal the effects of the film parameter uncertainty on the buckling deformation. The results obtained illustrate the probabilistic relation between buckling deformation and uncertain parameters, and are useful for accurate and reliable buckling design in terms of probability.

• Steel and Composite Structures
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• v.17 no.5
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• pp.753-776
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• 2014

In this paper, nonlinear vibration and post-buckling analysis of beams made of functionally graded materials (FGMs) resting on nonlinear elastic foundation subjected to thermo-mechanical loading are studied. The thermo-mechanical material properties of the beams are assumed to be graded in the thickness direction according to a simple power law distribution in terms of the volume fractions of the constituents, and to be temperature-dependent. The assumption of a small strain, moderate deformation is used. Based on Euler-Bernoulli beam theory and von-Karman geometric nonlinearity, the integral partial differential equation of motion is derived. Then this PDE problem which has quadratic and cubic nonlinearities is simplified into an ODE problem by using the Galerkin method. Finally, the governing equation is solved analytically using the variational iteration method (VIM). Some new results for the nonlinear natural frequencies and buckling load of the FG beams such as the influences of thermal effect, the effect of vibration amplitude, elastic coefficients of foundation, axial force, end supports and material inhomogenity are presented for future references. Results show that the thermal loading has a significant effect on the vibration and post-buckling response of FG beams.

• Archives of Pharmacal Research
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• v.6 no.1
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• pp.69-73
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• 1983

It was reported from our laboratory that the rate of deterioration of the force of contraction was slower in heart from Panax ginseng extract treated rats. Present investigation was designed to elucidate the mechanism of the slow deterioration of contractility of ginseng treated hearts. Therefore, $^{45}Ca^{2+}$ Uptake by sarcoplasmic reticulum (SR) isolated from ginseng treated rate and control rats was studied. Rate weighing 150-250g were administered orally with ginseng ethanol extract (100mg/kg) for 10 days. Cardiac SR was isolated by differential centrifugation and $^{45}Ca^{2+}$ uptake was assessed by the Millipore method. Freshly isolated SR from treated as well as control animals did not show any differences, but after incubation for 30 and 60 min at 37.deg.C, $^{45}Ca^{2+}$ uptake of control animal SR was found to be greatly depressed. The SR of treated animal possessed a greater degree of resistance to incubation. Thus it can be concluded that ginseng may have an ability to sustain the normal function of the heart by sustaining Ca accumulation by SR involved with the excitationcontraction coupling processes.

• Computers and Concrete
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• v.20 no.6
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• pp.671-682
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• 2017

In this research, seismic response of pipes is examined by applying nanotechnology and piezoelectric materials. For this purpose, a pipe is considered which is reinforced by carbon nanotubes (CNTs) and covered with a piezoelectric layer. The structure is subjected to the dynamic loads caused by earthquake and the governing equations of the system are derived using mathematical model via cylindrical shell element and Mindlin theory. Navier-Stokes equation is employed to calculate the force due to the fluid in the pipe. Mori-Tanaka approach is used to estimate the equivalent material properties of the nanocomposite and to consider the effect of the CNTs agglomeration on the scismic response of the structure. Moreover, the dynamic displacement of the structure is extracted using harmonic differential quadrature method (HDQM) and Newmark method. The main goal of this research is the analysis of the seismic response using piezoelectric layer and nanotechnology. The results indicate that reinforcing the pipeline by CNTs leads to a reduction in the displacement of the structure during an earthquake. Also the negative voltage applied to the piezoelectric layer reduces the dynamic displacement.

• Advances in Computational Design
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• v.4 no.3
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• pp.307-326
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• 2019

A low computational cost semi-analytical method is developed, based on eigenfunction expansion, to study the vibration of rectangular plates subjected to a series of moving sprung masses, representing a bridge deck under multiple vehicle or train moving loads. The dynamic effects of the suspension system are taken into account by using flexible connections between the moving masses and the base structure. The accuracy of the proposed method in predicting the dynamic response of a rectangular plate subjected to a series of moving sprung masses is demonstrated compared to the conventional rigid moving mass models. It is shown that the proposed method can considerably improve the computational efficiency of the conventional methods by eliminating a large number of time-varying components in the coupled Ordinary Differential Equations (ODEs) matrices. The dynamic behaviour of the system is then investigated by performing a comprehensive parametric study on the Dynamic Amplification Factor (DAF) of the moving loads using different design parameters. The results indicate that ignoring the flexibility of the suspension system in both moving force and moving mass models may lead to substantially underestimated DAF predictions and therefore unsafe design solutions. This highlights the significance of taking into account the stiffness of the suspension system for accurate estimation of the plate maximum dynamic response in practical applications.

• Structural Engineering and Mechanics
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• v.71 no.5
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• pp.553-562
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• 2019

This paper presents the results of a study into the dynamic behaviour of a support structure of a mobile elevating work platform. The vibrations of the mechanical system of the observed structure are examined analytically, numerically, and experimentally. Within the analytical examination, a simple mathematical model is developed to describe free and forced vibrations. The dynamic analysis of the mechanical system is conducted using a discrete dynamic model with a reduced number of vibrational degrees of freedom. On the basis of the expression for the system energy, and by applying Lagrange's equations of the second kind, differential equations are derived for system vibrations, frequencies are determined, and the laws of forced platform vibration are established. At the same time, a nonlinear FEM model is developed and the laws of free and forced vibration are determined. The experimental and numerical part of the study deal with the examination of the real structure in extreme conditions, taking into account: the lowest eigenfrequency, forced actions that could endanger the general stability, the maximal amplitudes, and the acceleration of the work platform. The obtained analytical and numerical results are compared with the experiments. The experimental verification points to the adverse behaviour of the platform in excitation cases - swaying. In such a situation, even a relatively small physical force can lead to unacceptably high amplitudes of displacement and acceleration - exceeding the usual work values.

• Structural Engineering and Mechanics
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• v.71 no.4
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• pp.351-361
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• 2019

Present article deals with the static stability analysis of compositionally graded nanocomposite beams reinforced with graphene oxide powder (GOP) is undertaken once the beam is subjected to an induced force caused by nonuniform magnetic field. The homogenized material properties of the constituent material are approximated through Halpin-Tsai micromechanical scheme. Three distribution types of GOPs are considered, namely uniform, X and O. Also, a higher-order refined beam model is incorporated with the dynamic form of the virtual work's principle to derive the partial differential motion equations of the problem. The governing equations are solved via Galerkin's method. The introduced mathematical model is numerically validated presenting a comparison between the results of present work with responses obtained from previous articles. New results for the buckling load of GOP reinforced nanocomposites are presented regarding for different values of magnetic field intensity. Besides, other investigations are performed to show the impacts of other variants, such as slenderness ratio, boundary condition, distribution type and so on, on the critical stability limit of beams made from nanocomposites.

• Steel and Composite Structures
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• v.39 no.5
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• pp.543-564
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• 2021

In this study free vibration analysis of a cracked Goland composite wing is investigated. The wing is modelled as a cantilevered beam based on Euler- Bernoulli equations. Also, composite material is modelled based on lamina fiber-reinforced. Edge crack is modelled by additional boundary conditions and local flexibility matrix in crack location, Castigliano's theorem and energy release rate formulation. Governing differential equations are extracted by Hamilton's principle. Using the separation of variables method, general solution in the normalized form for bending and torsion deflection is achieved then expressions for the cross-sectional rotation, the bending moment, the shear force and the torsional moment for the cantilevered beam are obtained. The cracked beam is modelled by separation of beam into two interconnected intact beams. Free vibration analysis of the beam is performed by applying boundary conditions at the fixed end, the free end, continuity conditions in the crack location of the beam and dynamic stiffness matrix determinant. Also, the effects of various parameters such as length and location of crack and fiber angle on natural frequencies and mode shapes are studied. Modal analysis results illustrate that natural frequencies and mode shapes are affected by depth and location of edge crack and coupling parameter.

• Journal of the Korean Society of Visualization
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• v.20 no.2
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• pp.70-77
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• 2022

Skeletal muscle tissues feature cellular heterogeneity, including differentiated myofibers, myoblasts, and satellite cells. Thanks to the presence of undifferentiated myoblasts and satellite cells, skeletal muscle tissues can self-regenerate after injury. In skeletal muscle regeneration, the collective motions among these cell types must play a significant role, but little is known about the dynamic collective behavior during the regeneration. In this study, we constructed in vitro platform to visualize the migration behavior of skeletal muscle cells in specific conditions that mimic the biochemical environment of injured skeletal muscles. We then visualized the spatiotemporal distribution of stresses arising from the differential collectiveness in the cellular clusters under different conditions. From these analyses, we identified that the heterogeneous population of muscle cells exhibited distinct collective migration patterns in the injury-mimicking condition, suggesting selective activation of a specific cell type by the biochemical cues from the injured skeletal muscles.

• Advances in Computational Design
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• v.7 no.1
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• pp.19-35
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• 2022

In this paper, the optimum location of the belt truss-outrigger for a combined system of framed tube, shear core and outrigger-belt truss is calculated. The optimum location is determined by maximization of the first natural frequency. The framed tube is modeled using a non-prismatic cantilever beam with hollow box cross section. The governing differential equation is solved using the weak form integral equations and the natural frequencies of the structure are calculated. The graphs are introduced for quick calculation of the first natural frequency. The location of the belt truss-outrigger that maximizes the first natural frequency of the structure is introduced as an optimum location. The structure is modeled using SAP-2000 finite elements software. In the modelling, the location of the belt truss-outrigger is changed along the height of the structure. With various locations of the outrigger, the lateral deflection of the all stories and axial force in the columns of the outer tube are calculated. The analysis is repeated by locating the outrigger-belt truss at the optimum location. The analysis results are compared and effect of the optimum location on the lateral deflection and the shear lag phenomena are investigated.