• Natural Product Sciences
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• v.26 no.3
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• pp.244-251
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• 2020

This study investigated therapeutic candidates with anti-inflammatory potential among traditional dietary ingredients targeting inflammatory bowel disease (IBD). Both Avena sativa and traditional fermented products, such as Korean soy paste, are popular health foods. We investigated the anti-inflammatory effects of soy paste combined with A. sativa (KDA), compared with soy paste without A. sativa (KD) by evaluating the expression of pro-inflammatory cytokines in lipopolysaccharide-stimulated RAW264.7 mouse macrophages and HT-29 human colon epithelial cells. KDA significantly inhibited the production of nitric oxide (NO) and downregulated the pro-inflammatory cytokines, such as interleukin (IL)-1β, IL-6, and tumor necrosis factor-α in lipopolysaccharide (LPS)-induced RAW264.7 cells. In another in vitro experiment involving LPS-stimulated HT-29 cells, KDA suppressed the levels of IL-8, which is the chemokine elevated in IBD. In addition, KDA exhibited anti-oxidative properties, such as 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and 2,2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) (ABTS) radical scavenging activity. Our findings revealed that A. sativa combined with soy paste exhibits a synergistic anti-inflammatory and anti-oxidant effect following fermentation. These results suggest that KDA may be used as a potential anti-inflammatory therapy against IBD.

• Journal of Korean Medical classics
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• v.27 no.4
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• pp.85-99
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• 2014

Objectives : Junsaengpaljeon(遵生八牋), a book specialized in curing was published during Ming Dynasty, addressing the significance on food through Eumchanboksikjeon(飮饌服食牋). Therefore, the objective of this study is to investigate the importance and utilization of food in curing from the perspective of author Goryum(高濂). Methods : Junsaengpaljeon released by InMinWiSaeng publisher was used in this study. The author and reference books were investigated, as well as the composition and contents of Eumchanboksikjeon. This study also focused on the utilization of food cure in Eumchanboksikjeon. Results : Volume 11 to 13 in Junsaengpaljeon is about Eumchanboksikjeon. Volume 11 is composed of Seokojaeron(序古諸論), Darchunyu(茶泉類), Tangpoomyu(湯品類), Sooksuyu(熟水類), Jukmiryu(粥糜類), Kwacillbunmiunyu(果實粉麵類), Pojaryu(脯鮓類) and Chisicryubeopjoerye(治食有法條例), whereas volume 12 is composed of Gasoyu(家蔬類), Yasoryu(野蔬類), Onjoryu(醞造類) and Kookryu(麯類). Volume 13 is composed of Chumsikyu (甛食類), Beopjeyakpumryu(法製藥品類), Boxsicbongyu(服食方類) and Gojaronbangjungyakmuljihae(高子論房中藥物之害). Especially volume 11 proposed the recipe and efficacy of Tangpoomyu(湯品類), Sooksuyu(熟水類), Jukmiryu(粥糜類) and Kwacillbunmiunyu(果實粉麵類), which can be used in food curing. Conclusions : Junsaengpaljeon Eumchanboksikjeon is a book complied the foods of Ming Dynasty with the description of dietetics theory. Especially this book covers Boxsicbong(服食方) and its dietary therapy prescription, and food for elderly health; it is, therefore, highly useful in applying various areas.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.3 no.2
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• pp.227-231
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• 2000

Pellagra is a systemic disease associated with neuropathy, caused by dietary insufficiency of nicotinic acid and it's precursor, tryptophan, which are vital to the function of cellular dehydrogenases in tissue respiration. Clinical triads are dermatitis, dementia, and diarrhea. The authors experienced a case of pellagra in 5-year old girl. She had a history of acrodermatitis enteropathica, three years ago. Erythematous scaly patches and hyperpigmentation developed on her great toes, bilaterally. Diarriea and ataxic gait were also noted. After vitamin B complex with nicotinamide therapy, diarrhea and dermatitis were dramatically improved within a few days, and ataxic gait was gradually improved.

• Journal of Yeungnam Medical Science
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• v.21 no.2
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• pp.133-142
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• 2004

Chronic obstructive pulmonary disease(COPD) is characterized by a not entirely reversible limitation in the airflow. An airflow limitation is progressive and associated with an abnormal inflammatory response of the lung to gases and harmful particles. In COPD, the weight loss is commonly observed and there is a negative impact on the respiratory as well as skeletal muscle function. The pathophysiological mechanisms that result in weight loss in COPD are not fully understood. However, the mechanisms of weight loss in COPD may be the result of an increased energy expenditure unbalanced by an adequate dietary intake. The commonly occurring weight loss and muscle wasting in COPD patients adversely affect the respiratory and peripheral muscle function, the exercise capacity, the health status, and even the survival rates. Therefore, it is very valuable to include management strategies that the increase energy balance in order to increase the weight and fat free mass. A Better understanding of the molecular and cellular pathological mechanisms of COPD can improve the many new directions for both the basic and clinical investigations. The Nutritional supply is an important components of a multidisciplinary pulmonary rehabilitation program. Future studies combining an exercise program, the role of anabolic steroids, nutritional individualization, a more targeted nutritional therapy, and the development of new drugs including anti-cytokines is needed for the effective management of COPD.

• The Journal of Korean Medical History
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• v.25 no.1
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• pp.61-69
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• 2012

A growing number of people shows deep interests in healthcare and treatments for the elderly with increasing their population. Contrary to general adults, old people have their own physiological and pathological characteristics. Therefore, treatments for the elderly should be different form those for others in younger generation. Alimentotherapy, which means the treatment or prevention by means of food, is one of the best way to deal with geriatrics that are chronic, multiple. Korea has its tradition and plenty of information in this field. Even in the early ChoSun Dynasty, when people suffered from lack of proper medical care, physicians used dietary prescriptions as active treatments, Therefore, we can find lots of cases in "Hyangyak-jibseogbang" and "Euibangyoochui" which are medical books published at that time. After that, a specialized alimentotherapy book, "Sikryochanyo" was written based on that kind of total medical volumes. With development of society, economy. and medical science, alimentotherapy has grown remarkably. Unlike in the early Chosun Dynasty, it was used positively for promoting general health condition and practiced as supportive method for medication in the late Chosun Dynasty. Considering the characteristics of the elderly, alimentotherapy is the most effective way to keep them healthy and can also used with medication.

• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.213-219
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• 2004

Obesity is the condition that excess fat stored in the body. Nowadays, the prevalence of obesity has greatly increased due to westernized dietary habits and changes in lifestyle. It has been proved that obesity is a risk factor of many diseases. Many methods were developed to find curative means for obesity and exercise and controlling diet were considered very effective ones. In order to find the theraputic effect of the exercise and food diary, we examined patients treated by electric accupuncture and ear accupuncture because of obesity. We observed 16 patients with obesity who visited KyungHee Univ., Kangnam Hospital of Oriental Medicine from November, 2002 to March, 2003. To rule out an bias, we excluded the patients who were treated for other disease or took medicine. Exercise in hospital was not effective for treatment of obesity, but keeping diary of diet was effcetive for the decrease of body weight(p<0.05).

• Journal of Korean Academy of Nursing
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• v.32 no.5
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• pp.694-705
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• 2002

The purpose of this study is to describe the health behavior experience of middle-aged Korean women in rural areas, and to help understand their health practice, perceive their nursing needs and provide guidelines to developing appropriate nursing interventions. Method: The participants were 18 healthy middle-aged women living in rural areas, with no serious illness that require hospitalization. The data was collected through interviews and participant observation, analyzed by the grounded theory methodology of Strauss & Corbin(1997). The data collection period was from April to November of 2001. Result: Depending on the paradigm model, the central phenomenon was family-oriented pursuing of yangsaeng. The causal condition was less confidence on one's own health, responsibilities in caring for family. The contexts were cultural system. The intervening condition was information system, support system, limitation of approaching a medical institution. The action/ interaction strategies were yangsaeng through dietary practice, yangsaeng through promoting clothing and housing, yangsaeng through exercise, practice of folk therapy, yangsaeng through mental hygiene, and use of medical institution. The consequences were stabilization of body and mind, and stabilization of family. Conclusion: It is recommended for nurses to understand health behavior experience of middle-aged women, and provide nursing intervention with theoretical scheme and practical principles so that these women can pursue the family-oriented process of yangsaeng.

• Journal of Korean Academy of Rural Health Nursing
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• v.11 no.1
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• pp.15-22
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• 2016

Purpose: The purpose of this study was to analyze changes in body weight (kg) and body mass index (BMI) in middle-aged women following a 12 week exercise program. Methods: The obesity management program for primary health care posts, which consists of exercise therapy and dietary counseling, was provided for obese women aged 40 to 64 (N=15). General characteristics of the women and differences in body weight and BMI before and after the program were analyzed using SPSS 22.0. Results: The major findings of this study are as follows; Average body weight before the program was 65.7 kg, and it was significantly reduced to 63.9 kg after the program (z = -3.41, p = .001). The average level of BMI decreased considerably from 27.9 kg/m2 to 27.2 kg/m2 (z = -3.41, p = .001). Conclusion: The findings from this study show a significant decrease in body weight and BMI after the program. Continuous study is needed to develop a variety of obesity management programs for middle-aged obese women. When developing programs regional characteristics need to be considered and there is a need to confirm the effectiveness of the programs.

• Korean Journal of Hospice Care
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• v.5 no.2
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• pp.54-63
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• 2005

The purpose of this study is to examine the requirement for child life support specialist and fetal education for children with cancer. This research presented was composed with three chapters : First chapter, I presented the purpose, scope and definitions of this research. Second chapter, I defined about hospice care service for children with cancer and kind of pediatric cancer. And general characteristics of children with cancer, a understanding character of death and dietary therapy. Lastly, I defined and investigated about spiritual care. Third chapter, I concluded with some of findings and final suggestions based on the results. According to the developmental stages children with cancer are disability of communication competence and more dependence on their parents, therefore parents' decision making were more difficulty. And parents with a child who suffers from a cancer needs a counseling in order to discover the meaning of life. Parents' psychological experience about the caring for their child suffering from pediatric cancer was equal to broken hearts due to shadow of the child's death from time to time. In other words a parents with a child who suffers from a cancer needs comprehensive services such as hospice, consultor as well as wide experienced pediatrician and nurse. Child life support specialist can help them recover and improve their o주 potential strength in behalf of overcoming their difficulties. And pastoral counseling can help them reduce the fear and anxiety about unknown world and death. The systematically developed a school-based counseling program would help children adjust to the difficulties after a perfect cure because of children adjusted to school well when they have good peer relationships.

• Journal of Korean Medicine for Obesity Research
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• v.3 no.1
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• pp.1-6
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• 2003

Background: Recently, Obesity has become a social problem in all over the world including Korea. Dietary regulation, exercise and behavior modification therapy are used in the treatment of obesity, but until now, there have been many difficulties in treating it. Objectives: To examine in obese pre-menopausal Korean females the short-term efficacy for weight loss of an herbal formula (Slim-diet). Design: A 6-week longituidinal evaluation of a herbal formula (Slim-diet) in 35 pre-menopausal females (baseline age $31.6\;{\pm}\;6.1$) with body mass index > $25kg/m^2$. Body composition was measured using bioimpedence analysis (BIA) and dual energy X-ray absorptiometry (DXA). Anthropometry was done by same observer. Total cholesterol, total lipid, triglyceride, and LDL-cholesterol were measured. Results: Herbal formula (Slim-diet) treatment produced significant loss of weight (P < 0.001), percent of body fat (P < 0.001, both BIA and DXA) and waist circumference (P < 0.001). It also produced significant reduction of total cholesterol and total lipid levels (P < 0.05).