• Journal of Periodontal and Implant Science
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• 제44권2호
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• pp.71-78
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• 2014

Purpose: Host modulatory therapy has been proposed as a treatment for periodontal diseases. A class of herbal medicines, known to be immunomodulators, alters the activity of immune function through the regulation of informational molecules such as cytokines. In the current study, we tested the hypothesis that herbal immunomodulator drugs act as an adjuvant to scaling and root planing (SRP) in alleviating periodontal inflammation by improving clinical and biochemical parameters. Methods: Sixty healthy subjects (30 in each group) with moderate and severe chronic periodontitis were enrolled in a double-blind, placebo-controlled, double-masked randomised controlled trial. The control group was treated with SRP and a placebo, whereas the test group was treated with SRP followed by dietary supplementation of Septilin for 3 weeks. Periodontal clinical parameters and serum C-reactive protein (CRP) levels were evaluated for all patients at the baseline, 3 weeks, and 6 weeks. Results: Improved gingival index scores found in the test group as compared to the control group were found to be statistically significant only after 3 weeks (P<0.001). In contrast, the decrease in the sulcus bleeding index and pocket depth scores was statistically highly significant in the test group as compared to the control group after 3 weeks and 6 weeks (P<0.001). However, reduced clinical attachment level and CRP scores, as reflected in the test group as compared to the control group, were not found to be statistically significant after both 3 weeks (P>0.05) and 6 weeks (P>0.05). Conclusions: The results of this clinical-biochemical study suggest that dietary supplementation with herbal immunomodulatory agents may be a promising adjunct to SRP and may aid in improving periodontal treatment outcomes.

• 동아시아식생활학회지
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• 제15권3호
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• pp.283-291
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• 2005

This study was penonned to provide basic data that predict the usefulness of Gastrodiae rhizoma as food materials for oriental medicinal cuisine(YakSun). We measured the changes of regional cerebral blood flow(rCBF) and blood pressure(BP) in rats, following the intravenous injection of Gastrodiae rhizoma water extract The measurement was continually monitored by laser-doppler flowmeter and pressure transducer in anesthetized adult Sprague-Dawley rats for about two to two and half hours through the data acquisition system composed of MacLab and Macintosh computer. The results of this experiment were as follows. Gastrodiae rhizoma increased the changes of rCBF in rats significantly. The rCBF of Gastrodiae rhizoma did not change by pretreated propranolol, atropin, methylene blue and indomethacin. But the rCBF of Gastrodiae rhizoma was increased by pretreated L-NNA. Gastrodiae rhizaoma decreased the changes of BP significantly. The BP of Gastrodiae rhizoma did not change by pretreated propranolol, atropin, methylene blue and indomethacin. But the BP of Gastrodiae rhizoma was decreased by pretreated L-NNA. These results indicated that Gastrodiae rhizoma might increase the rCBF and the BP which related to nitric oxide synthesis. Also these results indicate that Gastrodiae rhizoma can be used as a safe and clinically applicable to diet therapy of cerebral cardiovascular disease.

• 동아시아식생활학회지
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• 제25권1호
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• pp.49-63
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• 2015

The purpose of this study was to investigate body recognition, eating patterns, and health status of female college students in Seoul according to body mass index. In this study, we classified subjects as underweight, normal weight, and obese according to BMI. The mean age of subjects was $20.69{\pm}1.72$ years. Average height, weight or BMI of subjects were $161.49{\pm}5.39cm$, $52.17{\pm}6.53kg$ and $20.01{\pm}2.35kg/m^2$, respectively. Body satisfaction rate was 11.5% for 'Yes', whereas body dissatisfaction rate was 88.5% (p<0.05). Body dissatisfaction rates for the 'overweight', 'body dissatisfaction' and 'underweight' groups were 54.7%, 37.5% and 3.1%, respectively. The most common reason for controlling weight was 52.8% for 'to look pretty', whereas 'stress' at 45.5% was the most common in the obese group. 'Exercise + diet therapy' was used by 48.7%, followed by 'hungry' (23.9%), 'exercise' (17.3%) and 'intermittent diet' (6.1%). 'Regular exercise' 35.3%, 'A good rest & sleep' 32.4% and 'Regular meals & taking nutrition' 26.6% were significantly important (p<0.05). Overeating was lower among obese subjects, whereas consumption of fried foods and high-fat meats was higher (p<0.05). These results suggest the need for proper nutrition education for college students.

• 대한유전성대사질환학회지
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• 제12권2호
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• pp.99-103
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• 2012

I형 타이로신혈증은 타이로신의 분해 과정 중 최종단계에 관여하는 효소인 fumarylacetoacetate hydrolase(FAH)의 결핍에 의한 대사 이상질환이다. 급성 I형 타이로신혈증은 치명적인 간부전이나 혈액응고장애와 같은 급성 임상증상이 나타난 이후에는 예후가 불량하였으나 최근에는 신생아 대사이상 선별검사를 통해 조기 진단이 가능해졌고 2-(2-nitro-4-trifluoro-methylbenzyol)-1,3 cyclohexanedione nitisinone (NTBC) 약물 치료로 타이로신혈증의 치료 성적이 향상됨에 따라 신생아 대사이사 선별검사를 통한 조기 진단과 조기 치료가 더욱 중요해졌다고 할 수 있다. 이에 저자들은 심각한 출혈이나 간부전과 같은 급성 이상 증상이 나타나기 전 신생아 대사이상 선별검사로 조기 진단 및 조기 중재적 치료로 양호한 경과를 보이고 있는 I형 타이로신혈증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 동아시아식생활학회지
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• 제15권5
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• pp.558-565
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• 2005

In this study, Schizandriae fructus which has been used in oriental medicine and folks remedy, was studied to apply to functional foods and oriental medicinal cuisine. The aim of this experiments was to investigate the effects of Schizandriae fructus water extract(SFE) on the renal function, plasma renin activity, plasma levels of aldosterone and arterial natriuretic peptide(ANP) in rats. Spargue-Dawley rats weigh 200g, were randomly assigned to 3 groups such as basal diet only(BDG), basal diet with $0.5{\mu}L/g$ SFE(LAG) and basal diet with $1.0{\mu}L/g$ SFE(HAG). The results were as follows. Water balance decreased significantly after administration for 2 weeks compared with the control period in HAG. Urine volume increased significantly after administration for 1 week compared with the control period in LAG and HAG. Urinary excretion of sodium increased significantly after administration for 1 week and for 2 weeks compared with the control period in LAG and HAG. Urinary excretion of creatinine increased significantly after administration for 2 weeks compared with the control period in HAG. Plama levels of ANL decreased significantly after administration of $SFE(0.5{\mu}L/g)$. Plasma levels of aldosterone decreased significantly after administration of $SFE(1.0{\mu}L/g)$. There results indicated that Schizandriae fructus can improve the renal function through increased urine volume and sodium excretion. These results imply that SFE could be used as a potent food resource for diet therapy or clinical nutrition.

• 동아시아식생활학회지
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• 제19권3호
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• pp.327-338
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• 2009

The purpose of this study was to obtain information from married women regarding obesity-related factors and psychological eating behaviors, and to compare those variables among three groups, namely underweight, normal, and obese. The participants completed questionnaires regarding general obesity-related factors, major food servings/day, physical activity, dieting behaviors, perceptions of body image, and psychological eating behaviors. The results were as follows: The obese women reported a higher percentage of family history of obesity (74.8%) than the normal (43.5%) or underweight (28.2%) women. Most of the obese women (90.0%) accurately perceived their body image compared to 72.5% of the underweight and 56.6% of the normal weight women(p<0.001). No significant differences were found among the three groups for daily hours of exercise or computer use. In the case of hours of television watched daily, significant differences were found among the groups (obese 104 min/day, normal 87 min/day, underweight 76/min, p<0.05). Only 17.9% of the obese women reported eating 2 servings of milk products/day and only 23.2% of them reported eating 3 servings of protein foods/day as compared to the normal (25.4%, 18.0%) and underweight (29.4%, 41.7%) (p<0.01) women. About 98% of the obese and 78.5% of the normal weight women wanted to loose weight compared to only 10% of the underweight women (p<0.001). Psychological eating behavior was significantly correlated with subject BMI ($r^2$=0.32, p<0.01). Also, more obese women were unsatisfied with their body and had emotional eating behaviors as compared to the normal and underweight women, and this was statistically significant (p<0.001). In conclusion, the obese women had high perception rates of their body image, but had negative-psychological eating behaviors. Special behavior therapy is needed for obese women who show body dissatisfaction, emotional eating behaviors, long hours of daily TV viewing, and low intakes of protein and milk products.

• Journal of Microbiology and Biotechnology
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• 제28권6호
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• pp.893-901
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• 2018

Influenza viruses that cause recurrent seasonal epidemics to humans can be controlled with vaccine and antiviral therapy. However, the medical treatments often exhibit limited efficacy in the elderly or immunosuppressed individuals. In these cases, daily uptake of probiotics may be an option to bring in health benefits against influenza. Here, we demonstrate the effects of probiotics Lactobacillus plantarum (Lp) and Leuconostoc mesenteroides (Lm) against seasonal and avian influenza viruses. As assessed by the plaque size reduction of human H1N1 and avian influenza H7N9 viruses, including green fluorescent protein-tagged H1N1 strain in cells, the selected Lp and Lm strains restrained viral replication in mouse lungs with statistical significance. Against lethal viral challenge, the Lp and Lm strains exhibited their beneficial effects by increasing the mean days and rates of survival of the infected mice. These results suggest that, despite rather narrow ranges of protective efficacy, the dietary supplement of Lactobacillus and Leuconostoc probiotics may promote health benefits against influenza.

• 동아시아식생활학회지
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• 제6권1호
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• pp.1-16
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• 1996

This study was conducted to obtain basic data for reinforcing and developing course programs in department of Food Science and Nutrition. For this purpose, data was collected from dietitians and professors who work at 2-and 4-year colleges. Results are as follows. 1. Many respondents (95.7%) support that It Is desirable to separate dietitian license into two types. Reasons are (1) specific knowledge required by job type is different(29.5%), and (2) to increse job performance (29.3%). 2. Most respondents(95.4%) agree that course programs are needed to be revised. Because (1) current programs are inadequate to provide specific knowledge required at field work (67.8%), and (2) the programs are not helpful to increase job performance of dietitians (54.1%). 3. Respondents of dietitians want to extend applied science area(37.7%) and reinforce lab training (63.1%), as principles of program revision. 4. Course titles which need to be reinforced are Internship(95.8%) and Lap training(67.8%). 5. Specialized areas which need to be reinforced are Food Service Managemant and Practical Training(90.9%), Nutrition Education and Guide(88.9%), Public Health Nutrition(79.0%), Basic Area for Clinics(85.6%), Basic area for Education and Counselling(87.1%), and Cooking Science(77.5%) 6. Courses which are needed to be reinforced by respondents(over 75% agree) are Computer Management for Food Service, Counselling, Nutrition and Disease, Diet Therapy, Quantity Cooking, Internship, Public Health (Health Care), Community Nutrition(Environment and Nutrition), Clinical Nutrition, Psychology, and Communication.

• 동아시아식생활학회지
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• 제6권1호
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• pp.17-31
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• 1996

In order to reinforce and develop major courses in dietitian producing department, this study analysed and compared the courses of Food Science and Nutrition-related studies at 4-year and 2-year college. Results of the study are as follows: 1. There is no difference In the number of major courses provided by universities(33.2 courses) and junior colleges(32.6 courses), and universities(103) showed higher than junior colleges(79.9) with respect to total credit of courses. 2. Food Chemistry had highest credit(universities=1,532, junior colleges=1,037), while Nutrition Education had lowest credit (universities= 143, junior colleges=99) in the distribution of courses by way of major or classification. 3. The number of courses provided by universities and junior colleges was similar by way of minor classification. Especially, courses related to Food Chemistry showed highest frequency (universities=15, junior college=11) and percentage of credit (universities=32.6 junior college=34.3%), while courses related to Nutrition Education were one subject and percentage of credit was 3.0%. 4. Compared to percentage of the number of questions occupied in national qualifying examination for dietitians, the percentage of the number of credit provided by courses programs is higher in Biochemistry(universites 10.6%, junior colleges 7.5%) and Food Chemistry and Principles of Cooking(universites 27.0%, junior colleges 25.2%), but is lower in Diet Therapy(universites 7.6%, junior colleges 6.7%) and Nutrition Education(universites 4.9%, junior colleges 4.8%)

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제27권1호
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• pp.31-38
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• 2016

Pharmacotherapy is considered the first line therapy in attention-deficit hyperactivity disorder (ADHD). Many patients also choose complementary medicine such as dietary supplements. Omega-3 has shown some efficacy for improving ADHD symptoms in several studies. The goal of this review is to integrate the previous research findings on omega-3 and understand the issues worth considering in the treatment of ADHD. The terms "attention deficit disorder with hyperactivity", "omega-3", and "dietary supplements" were searched on PubMed, Cochrane, and Google scholar. The search was further limited to clinical trials, reviews, and meta-analyses. Trials that examined treatments for ADHD, used randomized design, and placebo-controlled trials were included. Eighteen clinical trials with a total of 1,141 participants were included in this review. Fifteen trials had parallel designs, comparing an omega-3/6 polyunsaturated fatty acid (PUFAs) or a combination of both to a placebo and three compared omega-3/6 PUFAs to a placebo and psycho-stimulants. Seven of the included trials showed significant improvements in groups receiving omega-3/6 PUFAs compared to placebo groups, however, 11 trials showed no significant differences. Evidence that PUFAs supplementation provides benefits for ADHD was yet limited. Mixed results were due to selection variability criteria, variability of supplementation, and short follow-up intervals.