• 대한세포병리학회지
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• 제19권2호
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• pp.65-71
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• 2008

In Korea, the quality control(QC) program forcytopathology was introduced in 1995. The program consists of a checklist for the cytolopathology departments, analysis data on all the participating institutions' QC data, including the annual data on cytologic examinations, the distribution of the gynecological cytologic diagnoses, as based on The Bethesda System 2001, and the data on cytologic-histolgical correlation of the gynecological field, and an evaluation for diagnostic accuracy. The diagnostic accuracy program has been performed 3 times per year with using gynecological, body fluid and fine needle aspiration cytologic slides. We report here on the institutional QC data and the evaluation for diagnostic accuracy since 2004, and also on the new strategy for quality control and assurance in the cytologic field. The diagnostic accuracy results of both the participating institutions and the QC committee were as follows; Category 0 and A: about 94%, Category B: 4-5%, Category C: less than 2%. As a whole, the cytologic daignostic accuracy is relatively satisfactory. In 2008, on site evaluation for pathology and cytology laboratories, as based on the "Quality Assurance Program for Pathology Services" is now going on, and a new method using virtual slides or image files for determining the diagnostic accuracy will be performed in November 2008.

• 대한디지털의료영상학회논문지
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• 제10권1호
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• pp.13-19
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• 2008

Purpose : In sponge quality of the material in digital radiography environment coating because do position blocks two that do not become coating done positioning blocks two that do not become coating done positioning block and sponge quality of the material to testing bench image artifact's difference compare. Method of study : In digital radiography environment positioning block of different two products same sunshine or effect that image and positioning block artifact gents in image analyze. the target used positioning block 2 when examine hand, rib and examination condition did each differently according to used positioning block. reflex compared picture that do image and verify that examine first time. Result : 1. In sponge quality of the material coating in done product artifact appear. Did not appear in product that do not become coating. 2. Can know coating's existence, that artifact according to radish happens. 3. Quality of the material coating's existence, there was difference of slippage according to radish Conclusion : Quality of the material coating phenomenon that done positioning block thus, it may have to be considered that use after estimate degree that get in image.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2010년도 추계학술대회
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• pp.773-775
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• 2010

의료용 X-선 고전압발생장치는 작동 시 높은 용량의 입력전원이 필요하며, 만약 전원환경이 적합하지 않을 경우 X-선 고전압발생장치를 사용하지 못하거나 불안정한 작동으로 인해 원활한 작동이 불가능해 진다. 전원환경에 따라 제품이 불안정 할 경우 환자 진료에 지장이 생길 수 있는 것을 감안하여 상용전원을 사용하지 않고 의료용 X-선 고전압발생장치를 작동 할 수 있는 전원장치를 배터리를 활용하도록 하였다. 전원회로를 설계한 후 시제품을 제작하여 본 논문에 제시된 방법에 따라 상용전원과 배터리 전원을 각각 비교하여 의료용 X-선 고전압발생장치가 입력전원방식에 따라 어떤 특성과 효율을 가지고 있는지 확인하였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.98-101
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• 2009

최근에는 차량 진단을 위한 방법으로 차량 내 네트워크 방식이 사용되고 있으며, CAN(Controller Area Network), MOST, LIN, FlexRay와 같은 차량 프로토콜의 사용 증대로 인해 차량에 대한 분산 제어와 원하는 데이터를 실시간 모니터링 하기 위한 방법들이 모색되고 있다. 현재의 자동차의 경우 자가진단 점검단자인 OBD2(On Board Diagnostics)표준 DLC(Data Link Connector)커넥터를 이용한 진단용 모듈(스캐너)을 통해 차량을 진단 한다. 그러나 엔진과 동력전달 계통(Powertrain) 부분으로 진단이 국한되어 있고, 사용자 측면을 고려하지 못하였다. 따라서, 본 논문에서는 Ethernet port를 이용한 차량 진단 모니터링 시스템을 설계하여 CAN 프로토콜 차량 데이터를 송수신하고 PC를 이용하여 보다 간편하게 차량의 상태와 정보를 제공하고 진단할 수 있는 모니터링 시스템을 구현한다.

• Korean Journal of Radiology
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• 제19권6호
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• pp.1007-1020
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• 2018

Objective: To compare the diagnostic performance of cardiovascular magnetic resonance (CMR) myocardial perfusion at 1.5- and 3-tesla (T) for detecting significant coronary artery disease (CAD), with invasive coronary angiography (ICA) as the reference method. Materials and Methods: We prospectively enrolled 281 patients (age $62.4{\pm}8.3$ years, 193 men) with suspected or known CAD who had undergone 1.5T or 3T CMR and ICA. Two independent radiologists interpreted perfusion defects. With ICA as the reference standard, the diagnostic performance of 1.5T and 3T CMR for identifying significant CAD (${\geq}50%$ diameter reduction of the left main and ${\geq}70%$ diameter reduction of other epicardial arteries) was determined. Results: No differences were observed in baseline characteristics or prevalence of CAD and old myocardial infarction (MI) using 1.5T (n = 135) or 3T (n = 146) systems. Sensitivity, specificity, positive and negative predictive values, and area under the receiver operating characteristic curve (AUC) for detecting significant CAD were similar between the 1.5T (84%, 64%, 74%, 76%, and 0.75 per patient and 68%, 83%, 66%, 84%, and 0.76 per vessel) and 3T (80%, 71%, 71%, 80%, and 0.76 per patient and 75%, 86%, 64%, 91%, and 0.81 per vessel) systems. In patients with multi-vessel CAD without old MI, the sensitivity, specificity, and AUC with 3T were greater than those with 1.5T on a per-vessel basis (71% vs. 36%, 92% vs. 69%, and 0.82 vs. 0.53, respectively). Conclusion: 3T CMR has similar diagnostic performance to 1.5T CMR in detecting significant CAD, except for higher diagnostic performance in patients with multi-vessel CAD without old MI.

• 치위생과학회지
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• 제21권1호
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• pp.45-51
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• 2021

Background: Periodontal disease, also known as gum disease, is a major dental inflammatory disease with a very high prevalence; it is the main cause of tooth loss. Therefore, diagnostic biomarkers that can monitor gum inflammation are important for oral healthcare. Since the gingival crevicular fluid (GCF) adequately reflects changes in the periodontal environment, they have become a target for the development of effective diagnostic biomarkers for periodontitis. In the present study, the level of the target molecules suggested as diagnostic biomarkers for periodontitis were analyzed in GCF samples collected from healthy individuals and periodontitis patients. In addition, useful targets for the diagnosis of periodontitis were evaluated. Methods: GCF samples were collected from healthy individuals and periodontitis patients using absorbent paper points. SDS-PAGE and Coomassie staining were performed for protein analysis. The protein concentrations of GCF specimens were determined using the Bradford method. The levels of the target molecules appropriate for diagnosing periodontal disease were measured by ELISA, according to the manufacturer's protocol. Results: The protein concentration of GCF collected from periodontitis patients was 3.72 fold higher than that in an equal volume of GCF collected from healthy individuals. ELISA analysis showed that the level of interukin-6 (IL-6), IL-8, metalloproteinases 2 (MMP-2), MMP-9, tumor necrosis factor-alpha (TNF-α), azurocidin, and odontogenic ameloblast-associated protein (ODAM) were higher in the GCF samples from the periodontitis patients than in those from the healthy individuals. However, the level of IL-6 and TNF-α were relatively low (> 5 pg/ml). The prostaglandin E2 (PGE2) levels were not significantly different between the two GCF samples. Conclusion: These results indicate that IL-8, MMP-2, MMP-9, azurocidin, and ODAM are potentially useful diagnostic biomarkers for periodontitis; combining multiple biomarkers will improve the diagnostic accuracy of periodontitis.

• 대한한방부인과학회지
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• 제35권2호
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• pp.42-53
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• 2022

Objectives: The definition of Sanhupung (Puerperal wind disorder) has been varied and there has been a prior study to establish the definition, but no clear conclusion has been reached on diagnostic criteria. Therefore, the aim of this study was to clearly redefine the definition of Sanhupung using the Delphi method. Methods: This study used the Delphi technique. A panel consisting of 13 experts of Korean medicine, particularly in Obstetrics & Gynecology, participated in the Delphi survey that included answering the 3rd round survey. The Delphi survey was conducted by evaluating and correcting the questionnaire using e-mail. Results: Through the Delphi survey, we have reached an agreement regarding the diagnostic criteria of Sanhupung. They are as follows: 1) Sanhupung can be diagnosed based on basic symptoms. If one or more symptoms are expressed in the basic symptom group, it can be diagnosed as Sanhupung. It is diagnosed in detail as a pain type or a sensory impairment type according to the category of basic symptoms. 2) Incidental symptoms are not essential for diagnosis, and are referred to for checking general weakness and autonomic nervous system conditions. 3) In order to meet the diagnostic criteria, the symptoms should occur within 6 months after childbirth or miscarriage, and the cause of the symptoms should not be classified as other diseases. Conclusions: The diagnostic criteria of Sanhupung were suggested based on the Delphi survey among experts in the field. Further research is necessary to improve the reliability and validity of the criteria.

• Fisheries and Aquatic Sciences
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• 제24권11호
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• pp.351-359
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• 2021

The red sea bream iridovirus (RSIV) belonging to genus Megalocytivirus is responsible for red sea bream iridoviral disease (RSIVD) in marine and freshwater fishes. Although several diagnostic assays for RSIV have been developed, diagnostic sensitivity (DSe) and specificity (DSp) of real-time polymerase chain reaction (PCR) assays are not yet evaluated. In this study, we developed a TaqMan probe-based real-time PCR method and evaluated its DSe and DSp. To detect RSIV, the probe and primers were designed based on consensus sequences of the major capsid protein (MCP) genes from megalocytiviruses including RSIV, infectious spleen and kidney necrosis virus (ISKNV), and turbot reddish body iridovirus (TRBIV). The probe and primers were shown to be specific for RSIV, ISKNV, and TRBIV-types megalocytiviruses. A 95% limit of detection (LOD_95%) was determined to be 5.3 viral genome copies/µL of plasmid DNA containing the MCP gene from RSIV. The DSe and DSp of the developed real-time PCR assay for field samples (n = 112) were compared with those of conventional PCR assays and found to be 100% and 95.2%, respectively. The quantitative results for SYBR Green and TaqMan probe-based real-time PCR were not significantly different. The TaqMan probe-based real-time PCR assay for RSIV may be used as an appropriate diagnostic tool for qualitative and quantitative analysis.

• 정보관리학회지
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• 제41권1호
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• pp.1-30
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• 2024

본 연구의 목적은 장애 아동·청소년의 독서역량을 강화하기 위하여 진단도구 프로토타입을 개발하고 그 타당도 및 신뢰도를 분석함으로써 독서역량 진단프로그램 개발의 기초 자료를 제시하는 데에 있다. 본 연구는 문헌 및 사례 연구를 바탕으로 문항을 개발하고, 델파이 조사 및 실제 장애 아동·청소년을 대상으로 한 예비조사를 실시하고 분석하였다. 연구 결과, 표본 수가 적어 타당도와 신뢰도 분석에 한계는 있었으나 장애 아동·청소년의 독서역량 진단도구 프로토타입 개발과 함께 기초 데이터를 확보하였다. 향후 개발될 독서역량 진단프로그램은 장애유형별 특성, 빅데이터를 통한 데이터 수집 및 활용 방안, 진단 절차 및 진단 시 유의사항을 다양한 변인을 고려하여 웹·모바일로 확장하여 개발할 것을 제안하였다.

• 한국응용곤충학회:학술대회논문집
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• 한국응용곤충학회 2002년도 합동 춘계 학술발표회
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• pp.96-96
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• 2002