• Journal of The Korean Society of Inherited Metabolic disease
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• v.16 no.2
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• pp.62-69
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• 2016

Newborn screening of some urea cycle disorders has little benefits because of early severe symptoms before the result, low sensitivity (especially hypocitrullinemia) and poor prognosis. But in case of citrullinemia, citrin deficiency and argininosuccinic aciduria diagnosed as elevated citrulline, newborn screening is helpful for early diagnosis and treatment before the symptom. Distinction between the clinical forms of these diseases is based on clinical findings and biochemical results, however, they may not be clearcut. Treatment is different from each other, so exact diagnosis is essential. Here, the diagnostic algorithm for elevated citrulline after tandem mass screening has been proposed. Minimizing total process time from sampling to report of the results is important in Korea for diagnosis and treatment of these disorders.

• Journal of Korean Foot and Ankle Society
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• v.18 no.3
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• pp.87-92
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• 2014

Acquired adult flatfoot is a deformity characterized by a decreased medial longitudinal arch and a hindfoot valgus with or without forefoot abduction. The etiologies of this deformity include posterior tibial tendon dysfunction, rheumatoid arthritis, trauma, Charcot's joint, neurologic deficit, and damage to the medial spring ligament complex or plantar fascia. Among these, posterior tibial tendon dysfunction is the most well-known cause. Although posterior tibial tendon dysfunction has been regarded as a synonym of acquired adult acquired flatfoot, failure of the ligaments supporting the arch can also result in progressive deformity even without a posterior tibial tendon problem. The authors describe the pathophysiology, diagnosis, and nonoperative treatment of acquired adult flatfoot, focusing on posterior tibial tendon dysfunction.

• Phonetics and Speech Sciences
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• v.5 no.4
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• pp.43-51
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• 2013

The purpose of this study is to survey Speech-Language Pathologists' perception on evaluation and treatment of "swallowing disorders". An online questionnaire was sent to the 279 subjects attending undergraduate/graduate programs in speech therapy department and/or SLPs who work in various settings. The survey consisted of three parts: 1) background information and educational/clinical experiences that are associated with dysphagia (swallowing disorder), 2) the current state of diagnosis and treatment of dysphagia of clinical practice (certified SLPs only), 3) the recognition of diagnosis, treatment, education for dysphagia. Each item of the survey was scaled by the participants on a five-point Likert scale of 1 to 5 (1 being not at all and 5 being extremely) or self-reported answers. The results of the survey showed that SLPs have high interest in "swallowing disorder", but most of them regarded them very difficult to diagnose and treat. The reason is that they have not been trained as a swallowing specialist. Therefore it is necessary to provide more opportunities for education and practice to establish the expertise of SLPs.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.4 no.2
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• pp.197-209
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• 2009

Objectives : The purpose of this study is finding tendencies of diagnosis and treatment of the traffic accidental patients. Methods : We reviewed and analyzed all theses published by Korean research institution. And these theses were classified by year, field of study, reviewed by focusing on diagnosis and evaluation, treatment type. Results : 1. 72 articles were published since 1993. 2. Classified by the major field of study, the korean academy of oriental rehabilitation medicine accounted for 33 papers. 3. 7-Zone-Diagnostic system and Minnesota Multiphasic Personality Inventory were studied mostly. 4. To add pharmacopuncture or chuna treatments are effective. 5. Traffic accidental patients get satisfaction about Oriental medicine therapy but methods of medical treatment are restrictively. Conclusions : Oriental medicine treatment is the effective way to cure traffic accidental sequela, but we need further studies.

• Clinical and Experimental Pediatrics
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• v.53 no.11
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• pp.931-935
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• 2010

Juvenile idiopathic arthritis (JIA) is comprised of a heterogeneous group of several disease subtypes that are characterized by the onset of arthritis before the age of 16 years and has symptoms lasting at least 6 weeks. The previous classification of JIA included seven different categories, whereas its current classification was compiled by the International League of the Association for Rheumatology, and replaced the previous terms of "juvenile chronic arthritis" and "juvenile rheumatoid arthritis," which were used in Europe or North America, respectively, with the single nomenclature of JIA. As mentioned above, JIA is defined as arthritis of unknown etiology that manifests itself before the age of 16 years and persists for at least 6 weeks, while excluding other known conditions. The clinical symptoms of JIA can be quite variable. Several symptoms that are characteristic of arthritis are not necessarily diagnostic of JIA and may have multiple etiologies that can be differentiated with careful examination of patient history. The disease may develop over days or sometimes weeks, thereby making the diagnosis difficult at the time of presentation. To make a clinical diagnosis of JIA, the first step is to exclude arthritis with known etiologies. Of note, late treatment due to excessive delay of diagnosis can cause severe damage to joints and other organs and impair skeletal maturation. Therefore, early detection of JIA is critical to ensure prompt treatment and to prevent long-term complications including the likelihood of disability in childhood.

• Journal of Biomedical Engineering Research
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• v.30 no.1
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• pp.41-48
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• 2009

In this paper, we present the diagnosis system for swallowing disorder. There are some types of diagnosis device for swallowing disorder, for example, the video fluoroscopy, the nuclear medicine inspection, the endoscopy, EMG and motion analysis. But these systems need heavy devices or have dangerous nuclear exposure, so are uncomfortable for handicapped person. Our system has advantages of simplicity, accuracy and quantitative analysis. In addition to the diagnosis aspect, this system can be used to biofeedback treatment.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3651-3658
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• 2016

Computer-aided diagnosis of breast cancer is an important medical approach. In this research paper, we focus on combining two major methodologies, namely fuzzy base systems and the evolutionary genetic algorithms and on applying them to the Saudi Arabian breast cancer diagnosis database, to aid physicians in obtaining an early-computerized diagnosis and hence prevent the development of cancer through identification and removal or treatment of premalignant abnormalities; early detection can also improve survival and decrease mortality by detecting cancer at an early stage when treatment is more effective. Our hybrid algorithm, the genetic-fuzzy algorithm, has produced optimized systems that attain high classification performance, with simple and readily interpreted rules and with a good degree of confidence.

• The Journal of the Korean dental association
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• v.52 no.6
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• pp.363-369
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• 2014

The cutaneous sinus tract is an uncommon disease. It is difficult to diagnose exactly of odontogenic cutaneous sinus tract for dentists or dermatologists except experienced clinicians or previously known clinicians. Many patients may be treated with repeated surgical excisions, biopsies, and antibiotic medications, but most of them could be frustrated with the recurrence of disease. There are several methods for diagnosis of odontogenic cutaneous sinus tract - such as GP cone tracing, conventional computed tomography(CT), periapical x-ray imaging, and cone beam computed tomography(CBCT). This case report describes the diagnosis and treatment of odontogenic cutaneous sinus tract that referred from medical doctors.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3243-3248
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• 2016

Background: Stomach cancer is the fourth most common cancer and the second leading cause of death from cancer in the world. In Iran, this type of cancer has high rates of incidence and mortality. This study aimed to assess the survival rate of patients with stomach cancer and its determinants in Kurdistan, a province with one of the highest incidence rates of stomach cancer in the country. Materials and Methods: We studied a total of 202 patients with stomach cancer who were admitted to Tohid Hospital in Sanandaj from 2009 to 2013. Using Kaplan-Meier nonparametric methods the survival rate of patients was calculated in terms of different levels of age at diagnosis, gender, education, residential area, occupation, underweight, and clinical variables including tumor histology, site of tumor, disease stage, and type of treatment. In addition, we compared the survival rates using the log-rank test. Finally, Cox proportional hazards regression was applied using Stata 12 and R 3.1.0 software. The significance level was set at 0.05. Results: The mean age at diagnosis was $64.7{\pm}12.0$ years. The survival rate of patients with stomach cancer was 43.9% and 7% at the first and the fifth year after diagnosis, respectively. The results of log-rank test showed significant relationships between survival and age at diagnosis, education, disease stage, type of treatment, and degree of being underweight (P<0.05). Moreover, according to the results of Cox proportional hazards regression model, the variables of education, disease stage, and type of treatment were associated with patient survival (P<0.05). Conclusions: The survival rate of patients with stomach cancer is low and the prognosis is very poor. Given the poor prognosis of the patients, it is critical to find ways for early diagnosis and facilitating timely access to effective treatment methods.

• Clinical and Experimental Pediatrics
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• v.52 no.9
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• pp.976-983
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• 2009

Urinary tract infection (UTI), the most common bacterial disease in childhood, is frequently associated with urinary tract anomalies (15-50%) and can induce renal scarring, which is a cause of hypertension and chronic kidney disease. Despite the high risk of renal scarring in infancy, the diagnosis may be delayed due to its nonspecific presenting symptoms; moreover, over-diagnosis is frequent due to the contamination of urine samples. The delay in diagnosis and treatment may induce sepsis or renal scar, while over-diagnosis is responsible for unnecessary antibiotic treatment and costly urinary imaging studies. UTI guidelines have been ever-changing for the past three decades, but some controversial issues remain. This article is a revision of the previous KSPN (Korean Society of Pediatric Nephrology) guideline and addresses the recent controversies concerning childhood UTI.