• 성인간호학회지
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• 제29권2호
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• pp.211-223
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• 2017

Purpose: This study was designed to develop and test the Hope Scale for Korean cancer patients. Methods: The process for the development of the Hope Test was a selection of initial items drawn from a literature review and in-depth interviews. The selected items were assessed for content validity by experts. The Hope Scale was comprised of five factors and 30 preliminary items. The preliminary Hope Scale for Korean Cancer Patients (HS_KCP) was administered to 259 cancer patients from one university hospital and one cancer hospital in Busan. Data were analyzed using item analysis, factor analysis, Pearson correlation coefficients, and Cronbach's ${\alpha}$. Results: Eighteen items were selected for the final scale. Five factors (inner sense of control, trust and expectation for recovery of disease, interconnection, spirituality, emotional despair) evolved from the factor analysis, which explained 63.3% of the total variance. The convergent & discriminent validity was r=.83 (p<.001), r=-73 (p<.001). The internal consistency, Cronbach's ${\alpha}$ was .88 and reliability of the subscales ranged from .54 to .85. Conclusion: The Hope Scale for Korean cancer patients demonstrated acceptable validity and reliability. It can be used to assess the hope of cancer patients and is feasible within a clinical setting.

• Biotechnology and Bioprocess Engineering:BBE
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• 제5권1호
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• pp.44-47
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• 2000

Cell growth and DNA synthesis were studied from a cultured early- and late- pas- sage mouse aorta smooth muscle cell (MASMC) because the proliferation of vascular smooth muscle cell (VSMC) is a key factor in development of atherosclerosis. In this study, the cells were cultured in fetal bovine serum (FBS) and stimulated by growth factors such as thrombin and platelet-derived growth factor-BB (PDGF-BB). Compared to the number of early-passage MASMC (passage 3 to 9) the number of late-passage MASMC (passage 30 to 40) in a normal serum state was increased 2 fold at Day 1, 3 and 6 in culture, respectively. Incorporation of $[^3H]$ thymidine into DNA induced by serum, PDGF and thrombin in late-passage MASMC was greater than those in early-passage MASMC. We also examined whether intracellular zinc levels would be an aging factor or not. The intracellular zinc level in early- and late-passage MASMC was monitored by using the zinc probe dye N-(6-methoxy-8-quinolyl)-p-toluenesulfonamide. It is interested that late-passage MASMC increased the intracellular fluorescence level of zinc, more than the early passage MASMC did. The alterations of intracellular zinc level occur concurrently with changes in MASMC proliferation rate during aging. This data suggest that the age-associated changes in zinc concentrations may provide a new in vitro model for the study of smooth muscle cell differentiation.

• 대한가정학회지
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• 제35권5호
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• pp.141-150
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• 1997

The purpose of this study was the development of the parenting stress scale, necessary to understand the details of the difficulties for a working mother having children from infant to preschooler. Relevant works were reviewed to collect 44 items for the questionnaire from the previous researchs, and additional 34 are combined as a set of measure items. The 78 items were analyzed for the fitness of structure based on the chi-square test and Cramer's V coefficients, and 35 were selected as a final set for the questionnaire. Further factor analysis on the 35 items showed that they could be selected 32 items of the 35 item scale and composed of 3 subscales; namely, the first factor(12 items) as‘typical stress due to the parenting’, the second(12 items) as‘pressures pertaining to the parental role and distress’, and the third(8 items) as’guilty to the parenting by others’. This final questionnaire composed of 32 items was also tested for the concurrent validity based on Pearson's correlation with Goldberg's General Health Questionnaire (GHQ), which is a well-known index to represent the socio-psychological stress. The correlation factor is .41(p＜.001), which justifies the fitness of the newly designed questionnaire. To find the confidence level, the Cronbach α was evaluated, which results .88 for the overall questionnaire and ranges between .76 and .82 for each subcale. This parenting scale can be also utilized as a measure to exploit proper programs for the parent-child relations, parent education and rehabitilation of the family function.

• BMB Reports
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• 제42권5호
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• pp.260-264
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• 2009

Tumor necrosis factor-$\alpha$ (TNF-$\alpha$) exhibits cytotoxicity towards various tumor cells in vitro and induces apoptotic necrosis in transplanted tumors in vivo. It also shows severe toxicity when used systemically for the treatment of cancer patients, hampering the development of TNF-$\alpha$ as a potential anticancer drug. In order to understand the structure-function relation of TNF-$\alpha$ with respect to receptor binding, we selected four regions on the bottom of the TNF-$\alpha$ trimer that are in close contact with the receptor and carried out mutagenesis studies and computational modeling. From the study, various TNF-$\alpha$ muteins with a high therapeutic index were identified. These results will provide a structural basis for the design of highly potent TNF-$\alpha$ for therapeutic purposes. By conjugating TNF-$\alpha$ muteins with a high therapeutic index to a fusion partner, which targets a marker of angiogenesis, it could be possible to develop TNF-$\alpha$ based anticancer drugs.

• 한국지역사회생활과학회지
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• 제26권3호
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• pp.523-540
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• 2015

This study examines the structural relationships between service quality, satisfaction, and behavioral intentions in responsible tourism. In particular, the study focuses on moderating effects of age. Data were collected from 471 tourists from seven responsible tourism agencies. SPSS 20.0 and AMOS 18.0 were used for frequency, reliability, exploratory factor, confirmatory factor, and path analyses. The results of a exploratory factor analysis yield two dimensions of service quality (functional quality and technical quality). The results of structural equation modeling indicate that functional quality and technical quality had positive effects on satisfaction, which in turn had a positive effect on behavioral intentions. In addition, age moderated the relationships between service quality, satisfaction, and behavioral intentions such that functional quality had a positive effect on satisfaction in the group of tourists in their twenties and thirties and that functional quality and technical quality were important factors for tourists in their forties. The results are expected to help responsible tourism communities better manage service quality to increase tourist satisfaction.

• 성인간호학회지
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• 제14권4호
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• pp.554-563
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• 2002

Purpose: to develop an instrument to assess the rehabilitation motivation and to test its reliability and validity. Method: The data was collected with in-depth interviews of nine participants that include adults with disabilities acquired after they reached 18 years' of age. The development of the preliminary items was based on the theory of self-determination proposed by Deci & Ryan (1985) and the results from the analysis of the data. After these, appropriate specialists clarified the validity of the contents of the preliminary items twice. A test to reliability and validity was conducted with 186 disabled. A principal axis factor analysis with oblimin rotation was performed on 29 items. Result: Finally 27 items were selected. The 5-factor solution emerged as the most appropriate model for the data. The different types of motivation for rehabilitation were identified as: task-oriented motivation, change-oriented motivation, obligatory motivation, external motivation, and amotivation. The alpha coefficient of internal consistency was .85. Conclusion: The results of this study suggest that the instrument to measure motivation for the rehabilitation of the disabled may be a useful instrument with a high degree of reliability and validity.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.672-675
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• 2006

It is becoming more significant to develop a rotary VCM type actuator for small form factor ODD, as portables are getting more and more popularized nowadays. In this paper, the procedure of development of the actuator which is applicable to compact flash II card and is fit in the specification of BD 1X is explained. This is based on the rotary VCM type actuator, which is good for reducing thickness. Air core solenoid coil is used in order to do focusing mechanism. And the total weight is reduced by using the structure of steel-aluminium-steel triple layer, so, the stiffness is still adequate. Additionally, the tracking coil is moved next to the actuator, so the total length was reduced, then the actuator become applicable to compact flash II card. The force of Magnetic Circuit is improved by using Magnetic Circuit DOE. And flexible mode frequency improved through the DOE of structure part. Modeling was exactly done in consideration of air core solenoid coil and pivot bearing. It is confirmed that the designed model is satisfied with the specification of BD 1X and is applicable to Compact Flash II card.

• 대한가정학회지
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• 제43권5호
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• pp.93-105
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• 2005

This study focused on the development of scales measuring the characteristics related to appearance management behaviors of businessmen for on-line image consulting. The purposes of this study were, 1) to develop a tool which can measure the ideal image, 2) to develop a tool which can measure personality, and 3) to develop a scale measuring the physical characteristics and body cathexis. The data were collected from 380 businessmen in Seoul, Korea and were analyzed by frequency, factor analysis, reliability test, cluster analysis, correlation analysis, one-wav ANOVA and Duncan test. The results from this study were as follows .1)Five factors of the ideal image were identified: stylish, able, active, neat/confident and easy. The total variance was 74.29$\%$ and Cronbach's alpha of the 5 factors ranged from .74-.90. One item was selected to represent each factor. 2) Five factors of personality were identified: preference of social function, sociable, dynamic, achievement-motivated, and success-oriented. The totai variance was 60.63$\%$ and Cronbach's alpha ranged from .56-.83. One item was selected to represent each factor. 3) Five factors of body cathexis were identified: satisfaction with girth, length, physique, nose and eyes. The total variance was 73_46$\%$ and Cronbach's alpha ranged from .68-.85.

• KDI Journal of Economic Policy
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• 제34권2호
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• pp.95-137
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• 2012

외국인력 및 이민 유입은 경제 전반에 걸쳐 저숙련 노동공급을 증가시키는 효과를 가진다. 그 영향으로부터 완전히 독립적인 통제집단은 경제 내에 존재하지 않기 때문에 효과평가방법(impact evaluation method)에 의한 영향평가는 한계를 지닌다. 본 연구에서는 총요소비율 접근방법(aggregate factor proportions approach)을 채택하여 경제 내 저숙련 노동공급 증가의 효과를 추정함으로써 외국인 유입의 영향을 평가한다. 평가 결과는 외국인력 및 이민 유입은 숙련 노동력과 저숙련 노동력 간의 임금격차를 상당히 확대시키는 반면, 성장에 대한 기여는 크지는 않음을 제시한다. 그 이유는 국내에 유입되는 외국인력의 절대다수가 생산성이 낮은 단순인력이라는 데에 있다.

• 한국전문물리치료학회지
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• 제16권1호
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• pp.42-51
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• 2009

The purpose of this study was to develop a checklist of risk factors for quantitative assessment of musculoskeletal complaints in shipbuilding workers. A key point was to develop comprehensive a checklist including the worker's physical ability, as ergonomic and workload factors. ln the first, through correlation analysis between musculoskeletal complaints and physical abilities in shipbuilding workers, risk factors related to physical abilities were selected. In the second, after the development of a checklist was composed of physical, ergonomic and workload factors, factor analysis was used to test the validity of the developed checklist. Each factors selected finally showed that physical factors were hand grip strength, spinal curvature, and flexibility (sit to reach), ergonomic factors were posture, total exposed time, duration, and force of working, and workload factors were physical and psychological workload perceived by worker. The results showed that musculoskeletal complaints was associated with physical abilities (p<.05). The developed checklist had a reliability of .761 (Cronbach=.761) and a validity and explanation of 54.9%. The criterion of management was classified in 4 stages by relative weights of each factor. It is suggested that active intervention is needed to reduce musculoskeletal complaints in workers with more than a 14.31 score.