• 제목/요약/키워드: development control

검색결과 22,148건 처리시간 0.056초

CBP7 Interferes with the Multicellular Development of Dictyostelium Cells by Inhibiting Chemoattractant-Mediated Cell Aggregation

  • Park, Byeonggyu;Shin, Dong-Yeop;Jeon, Taeck Joong
    • Molecules and Cells
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    • 제41권2호
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    • pp.103-109
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    • 2018
  • Calcium ions are involved in the regulation of diverse cellular processes. Fourteen genes encoding calcium binding proteins have been identified in Dictyostelium. CBP7, one of the 14 CBPs, is composed of 169 amino acids and contains four EF-hand motifs. Here, we investigated the roles of CBP7 in the development and cell migration of Dictyostelium cells and found that high levels of CBP7 exerted a negative effect on cells aggregation during development, possibly by inhibiting chemoattractant-directed cell migration. While cells lacking CBP7 exhibited normal development and chemotaxis similar that of wild-type cells, CBP7 overexpressing cells completely lost their chemotactic abilities to move toward increasing cAMP concentrations. This resulted in inhibition of cellular aggregation, a process required for forming multicellular organisms during development. Low levels of cytosolic free calcium were observed in CBP7 overexpressing cells, which was likely the underlying cause of their lack of chemotaxis. Our results demonstrate that CBP7 plays an important role in cell spreading and cell-substrate adhesion. cbp7 null cells showed decreased cell size and cell-substrate adhesion. The present study contributes to further understanding the role of calcium signaling in regulation of cell migration and development.

무인항공기 체계의 통합검증을 위한 무인항공기 체계통합실험실(UAV SIL) 개발 (Development of Unmanned Aerial Vehicle System Integration Laboratory(UAV SIL) for the Integrated Verification)

  • 심재익;우희채;김상진;정상준
    • 한국군사과학기술학회지
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    • 제27권1호
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    • pp.70-79
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    • 2024
  • This paper describes the results of the development of the the unmanned aerial vehicle system integration laboratory(UAV SIL) for the integrated verification. This UAV SIL is designed to test the robustness of the UAV system including the operational logics and the flight control system behaviors under many abnormal and emergency conditions such as data-link losses, airborne subsystem failures, engine shut down conditions, and ground control station faults. This paper presents how to build the UAV SIL and how to verify the in-development UAV system through the UAV SIL.

측후방 충돌 회피를 위한 조향 보조 토크 및 차등 제동 분배 제어 알고리즘 개발 (Development of a coordinated control algorithm using steering torque overlay and differential braking for rear-side collision avoidance)

  • 이준영;김동욱;이경수;유현재;정혁진;고봉철
    • 자동차안전학회지
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    • 제5권2호
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    • pp.24-31
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    • 2013
  • This paper describes a coordinated control algorithm for rear-side collision avoidance. In order to assist driver actively and increase driver's safety, the proposed coordinated control algorithm is designed to combine lateral control using a steering torque overlay by Motor Driven Power Steering (MDPS) and differential braking by Vehicle Stability Control (VSC). The main objective of a combined control strategy is twofold. The one is to prevent the collision between the subject vehicle and approaching vehicle in the adjacent lanes. The other is to limit actuator's control inputs and vehicle dynamics to safe values for the assurance of the driver's comfort. In order to achieve these goals, the Lyapunov theory and LMI optimization methods has been employed. The proposed coordinated control algorithm for rear-side collision avoidance has been evaluated via simulation using CarSim and MATLAB/Simulink.

석탄화력발전소 보일러 노내압력 제어알고리즘과 분산제어시스템의 개발 (The Development of Boiler Furnace Pressure Control Algorithm and Distributed Control System for Coal-Fired Power Plant)

  • 임건표;허광범;박두용;이흥호
    • 전기학회논문지P
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    • 제62권3호
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    • pp.117-126
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    • 2013
  • This paper is written for the development and application of boiler furnace pressure control algorithm and distributed control system of coal-fired power plant by the steps of design, coding, simulation test, site installation and site commissioning test. The control algorithms were designed in the shape of cascade control for two parts of furnace pressure control and induced draft fan pitch blade by standard function blocks. This control algorithms were coded to the control programs of distributed control systems. The simulator for coal-fired power plant was used in the test step and automatic control, sequence control and emergency stop tests were performed successfully like the tests of the actual power plant. The reliability was obtained enough to be installed at the actual power plant and all of distributed control systems had been installed at power plant and all signals were connected mutually. Tests for reliability and safety of plant operation were completed successfully and power plant is being operated commercially. It is expected that the project result will contribute to the safe operation of domestic new and retrofit power plants, the self-reliance of coal-fired power plant control technique and overseas business for power plant.

Effects of the partially movable control fin with end plate of underwater vehicle

  • Jung, Chul-Min;Paik, Bu-Geun;Park, Warn-Gyu
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제9권1호
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    • pp.55-65
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    • 2017
  • Underwater torpedo has control fin with very low aspect ratio due to launching from limited size of cylindrical torpedo tube. If the aspect ratio of control fin of underwater vehicle is very low three-dimensional flow around control fin largely reduces control forces. In this study, the end plate was applied to reduce the three-dimensional flow effects of partially movable control fin of underwater vehicle. Through numerical simulations the flow field around control fin was examined with and without end plate for different flap angles. The pressure, vorticity, lift and torque on the control fin were analyzed and compared to experiments. The comparison have shown a reasonable agreement between numerical and experimental results and the effect of end plate on a low aspect ratio control fin. When the end plate was attached to the movable control fin, the lift increased and the actuator shaft torque did not significantly change. As this means less consumption of the actuator shaft torque compared to the control fin that has the same control force, the inner actuator capacity can be reduced and energy consumption can be saved. Considering this, it is expected to be effectively applied to the control fin design of underwater vehicles such as torpedoes.

원유의 WSF (water soluble fraction)가 참굴의 초기생활사에 미치는 영향 (Effect of Crude Oil (WSF) on Early Life Stage of the Pacific Oyster, Crassostrea gigas)

  • 신윤경;김응오;조기채;전제천;진영국
    • Environmental Analysis Health and Toxicology
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    • 제25권2호
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    • pp.161-168
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    • 2010
  • The observed the toxic effect of WSF (Water Soluble Fraction) on development time, development rate, attachment rate, survival rate and growth of the larva during the early stage of the Pacific oyster, Crassostrea gigas. The time required early juvenile from the fertilized eggs exposed to crude oil (WSF) was about 13 hours in control group. But that of the crude oil dose group takes 12 hours, with shorter compared to control group. Development and attachment rate of the oyster significantly higher in 0.4 and 0.8 mg/L WSF compared to control group (P<0.05) but significantly lower more than 1.6 mg/L WSF (P<0.05). Survival rate of the oyster larva significantly higher in 0.4 and 0.8 mg/L WSF compared to control group (P<0.05) but significantly lower more than 2.4 mg/L WSF (P<0.05). Survival rate of spot showed no significantly difference compared to control group (P>0.05). Shell growth of the oyster were significantly lower more than 1.6 mg/L WSF compared control group (P<0.05). The effect concentration of crude oil showed that more 0.4 mg/L in development and attachment rate and more 1.6 mg/L in growth. Also, chronic exposure of crude oil even effect also in low concentration.

낫도균을 이용한 닭 생산생과 질병예방에 관한 연구 (Studies on the supplementation of fermented soybean by Bacillus subtilis (natto) on performances, prevention against disease in broilers)

  • 권미순;이지영;박인규;윤여백;정동석
    • 한국동물위생학회지
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    • 제29권3호
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    • pp.257-266
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    • 2006
  • The present study was done to investigate the effect of dietary supplemental freezer dry powder fermentation soybean by Bacillus subtilis (natto) on the growth performance and intestinal microflora, prevention of fowl typhoid infection, the uptake of vegetative diet in broiler chickens. The chickens were fed control diet (supplement antibiotics) and fermentation soybean (0.75, 1.5, 3%) diets. A total of 280 one day old broiler chickens with randomly mixed sexes were fed the four diets for 6 weeks. Body weight gain of chicken fed 1.5% fermentation soybean by B subtilis tend to increase higher than the control from 6th week. Chickens fed diets containing 1.5% fermentation soybean by B subtilis had higher intake than those fed the other levels to the 3th weeks, but lower than control from the 4th week to the 6th week. Feed conversion also improved significantly in the supplemental 1.5% fermentation soybean by B subtilis from the 4th week to the 6th week. The number of B subtilis and Lactobacillus spp in the ileum and cecum tend to increase in the supplemental fermentation soybean by B subtilis at 6 week of age, but was not significantly different. In the nutrient digestibility, the feed conversion on the supplemental 1.5% fermentation soybean by B subtilis was better than the control and the weight of drying feces lower than the control. In test of S. gallinarum intramuscular inoculation, reisolation rate of S gallinarum in liver and feces 1.5% the fermentation soybean by B subtilis 75% (liver), 17% (feces) had decreased than the control.

Biological Control of Aphid Using Fungal Culture and Culture Filtrates of Beauveria bassiana

  • Kim, Jeong Jun;Jeong, Gayoung;Han, Ji Hee;Lee, Sangyeob
    • Mycobiology
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    • 제41권4호
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    • pp.221-224
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    • 2013
  • Aphids are one of the most destructive pests in crop production such as pepper, cucumber, and eggplants. The importance of entomopathogenic fungi as alternative pest control agents is increasing. Conidia of entomopathogenic fungi are influenced by environmental conditions, such as temperature and relative humidity, and cause slow and fluctuating mortality. These factors have prevented wider application and use of biocontrol agents. For investigation of means of mitigation of such problems, we conducted bioassays with 47 fungal culture filtrates in order to evaluate the potential of secondary metabolites produced by entomopathogenic fungi for use in aphid control. Among 47 culture filtrates cultured potato dextrose broth, filtrate of Beauveria bassiana Bb08 showed the highest mortality (78%) against green peach aphid three days after treatments. Filtrate of Bb08 cultured in Adamek's medium showed higher toxicity as 100% to third instar nymphs of the aphid compared with seven other filtrates cultured in different broths amended with colloidal chitin or oil. The culture filtrates and fungal cultures from media amended with colloidal chitin or oil had lower control efficacies than filtrates without these additives in three different media. These results indicate that the fungal culture fluid or culture filtrate of B. bassiana Bb08 cultured in Adamek's medium has potential for development as a mycopesticide for aphid control.

태평양 Argo 자료의 지연모드 품질관리 및 검증연구 (Delayed Mode Quality Control of Argo Data and Its Verification in the Pacific Ocean)

  • 양준용;강성윤;고우진;서영상;서장원;석문식
    • 한국환경과학회지
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    • 제17권12호
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    • pp.1353-1361
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    • 2008
  • Quality control of Argo(Array for Real-time Geostrophic Oceanography) data is crucial by reason that salinity measurements are liable to experience some drift and offset due to biofouling, contamination of sensor and wash-out of biocide. The automated Argo real-time quality control has a limit of sorting data quality, so that WJO program is adopted as standardized method of Argo delayed mode quality control (DMQc) in the world that is a precise quality control method. We conducted DMQC on pressure, temperature and salinity measured by Argo floats in the Pacific Ocean including expert evaluation. Particularly, salinity data were corrected using WJO program. 4 salinity profiles of Argo delayed mode were compared with nearby in situ CTD data and other Argo data in deep layer where oceanographic conditions are stable in time and space. The differences of both salinities were lower than target accuracy of Argo. As compared with the difference of salinities before DMQC, those after DMQC decreased by 60-80 percent. Quality of delayed mode salinity data seemed to be improved correcting salinity data suggested by WJO program.