• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.22 no.2
• /
• pp.151-155
• /
• 2011

Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Subjects and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

• Korean Journal of Food Science and Technology
• /
• v.26 no.3
• /
• pp.199-203
• /
• 1994

Software for refrigerator capable of both rapid fermentation and suitable storage of Kimchi was developed and its performance was investigated. Refrigerator system consists of an insulated fermentation room, heater, damper for the control of outer cold air and two sensors for recognizing temperature of heater and fermentation room, which control temperature and time period of affecting Kimchi fermentation. Effects of fermentation at different NaCl concentration and three fermentation function keys were studied; At key I, time which was elapsed to edible ripening state, pH 4.5 and total acid 0.6%, was about $3{\sim}4$, $4{\sim}5$ and $11{\sim}12$ days, respectively. At key II, time was about $2{\sim}3$, $3{\sim}4$, and $10{\sim}11$ days, and at key III, about 2, 3 and $9{\sim}10$ days, respectively. Effect of storage at three fermentation function keys was all maintained to the level of a palatable pH range until 14 days. Sensory evaluation of Kimchi showed also significant difference in a taste.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.20 no.2
• /
• pp.166-174
• /
• 2018

Potato(Solanum tuberosum L.) is one of the major food crop in the world following rice, wheat, and maize. It is thus important to project yield predict of potato under climate change conditions for assessment of food security. A crop growth modelling is widely used to simulate crop growth condition and total yield of various crops under a given climate condition. The decision support system for agrotechnology transfer (DSSAT) cropping system model, which was developed by U.S. which package integrating several models of 27 different crops, have been used to project crop yield for the impact assessment of climate change on crop production. In this study, we simulated potato yield using RCP 8.5 climate change scenario data, as inputs to the DSSAT model in five regions of Korea. The genetic coefficients of potato cultivar for 'superior', which is one of the most widely cultivated potato variety in Korea were determined. The GenCalc program, which is a submodule of the DSSAT package, was used to determine the genetic coefficients for the superior cultivar. The values of genetic coefficients were validated using results of 39 experiments performed over seven years in five regions. As a case study, the potato yield was projected that total yields of potato across five regions would increase by 26% in 2050s but decrease by 17% in 2090s, compared with 2010s. These results suggested that the needs for cultivation and irrigation technologies would be considerably large for planning and implementation of climate change adaptation for potato production in Korea.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.4
• /
• pp.1576-1581
• /
• 2013

In the present study, the performance of a PF heat exchanger for heat pump dryer was investigated. Capacity and dehumidification amount of the PF heat exchangers(PF1, PF2, PF3) by different inclination angles($0^{\circ}$, $30^{\circ}$, $60^{\circ}$) were studied. Experimental conditions were an air velocity crossing to the heat exchanger(0.5m/s), an air dry-bulb temperature($60^{\circ}C$) and relative humidity(70%). The experimental results have shown that the performance of the inclined PF heat exchangers was better than that of the vertically installed one. PF3 showed better performance compared to PF1 and PF2 due to the large pin pitch which are leading to more draining for dehumidified water. But, capacity and dehumidification amount of the PF heat exchanger at the inclination angles of $60^{\circ}$ was decreased due to pressure drop. Also, to predict the experimental data of the PF heat exchanger, the performance program was developed for the inclination angles of $0^{\circ}$. PF heat exchanger performance between experiment data and calculation data was satisfied within the maximum 2% for capacity and 3% for dehumidification amount.

• Korean Security Journal
• /
• no.17
• /
• pp.109-129
• /
• 2008

The purpose of this study is to analyze the relationship of market orientation, and business performance in the security firms. To achieve the goal of the study, it has used various methods to study. First of all, it has carried out documentary surveys through literatures review on market orientation and business performance of the security firms, and practical researches side by side. In the documentary surveys, it has developed the framework of study and questionnaires based on the domestic and foreign books, theses, materials of public institutions, and other materials. In the practical researches, basing on the selected study models and hypotheses, it has selected 15 security companies which are located in Seoul, Gyeonggi and Chungcheong Provinces with the stratified cluster random sampling method. It has polled the employees of the security companies for about 2 months from 5 August to 10 October 2006, distributing 20$\sim$50 pieces per company. It has distributed 600 pieces and used 565 pieces for analysis excepting unfaithful 35 pieces. The collected questionnaires were analyzed by SPSSWIN 14.0 program. and The methods to analyze the materials were factor analysis, reliability analysis, correlation analysis, multiple regression analysis, and path analysis through regression analysis. The results obtained from the study using analysis methods above are as follows. Finally, market orientation influences on business performance. In other words, the higher market orientation is, the better financial and non financial outcomes are.

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2006.11a
• /
• pp.65-74
• /
• 2006

Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.37 no.5
• /
• pp.891-903
• /
• 2017

In recent days, school violence has been rising as a significant social problem. The occurrence of school violence can be fueled by a wide range of social and environmental contexts, thus it is very difficult to come up with the ultimate solution. Community CPTED program is one of the more comprehensive set of efforts that has been developed to prevent crime in general, and the primary focus of the study is to investigate suitable components of CPTED to prevent school violence based on the physical conditions of communities as well as the perception of residents outside of school grounds, in the vicinity of schools. Three sets of analyses in series were employed in the research. First, Ward's minimum-variance cluster analysis was used to classify the places where school violence can occur outside of school grounds based on the physical conditions recognized by local residents. Next, Importance-Performance Analysis was performed to analyze the perception of local residents about the importance and the effectiveness of CPTED components in preventing school violence. Subsequently, Ordered Logit Model was used to analyze the local residents' awareness on safety regarding school violence in their community space. Combining the results of the analyses, the priority of the community CPTED applications to prevent school violence outside of school was derived. Reflecting the local residents' perception on safety of students in their community, the sense of security in communities against school violence can be reinforced by the communities' sensible efforts in creating safer environment for their students.

• Journal of Mushroom
• /
• v.13 no.3
• /
• pp.233-236
• /
• 2015

This report is the result of devising a method for utilizing the device of the load cell to maintain a constant water content of the medium every day to prepare a cultural substrates with the mixer for growing mushrooms bottle cultivation. A load cell was device under the medium mixer. It is developed when the device reaches the weight calculated as amount of substrate bottled and number of the bottle, it is automatically terminated by water injection. In addition, measuring the water content of each medium and the total weight of the medium reaches the target moisture content were calculated by using the program Cheong et al. (2015). Enter the total weight of the medium on the display unit of the load cell, when starting the water supply to reach the weight-based mixing media, the water supply is stopped. This method can improve the convenience by reducing the user's trouble in repeated work medium prepared by automating water supply. The suitable moisture content of the mixed medium for some kind of mushroom can be improved by the composition accuracy. And mycelial culture period, primordial period, mushroom growing period is maintained even of the medium can be produced stably. Therefore, it is possible to achieve a stable management of the mushroom farm according to mushroom quality and quantity stable throughout the year.

• Journal of Biosystems Engineering
• /
• v.8 no.1
• /
• pp.61-69
• /
• 1983

A system dynamic model was developed to predict food grain production under the dynamic consideration of the production circumstance and inputs such as farm population, investment on agriculture, arable land, extensive technology and weather. By using the model, the variation of the food grain production from 1978 to 2008 was examined. The results of the model output says it is desirable that the persistent and long-term program should be studied to get necessary food grain production under the variational inputs and circumstances.

• Journal of Korean society of Dental Hygiene
• /
• v.10 no.5
• /
• pp.851-860
• /
• 2010

Objectives : This study examined the oral health behavior and dental services utilization of adolescents in order to provide information on how to disseminate the correct oral health behavior to the youth and develop programs for the approach. Methods : The raw data of 'The Third 2007 Youth Health Behavior Online Survey' carried out by the Korea Center for Disease Control and Prevention were analyzed. All survey data collected was processed using SPSS ver 17.0 for data analysis as Frequency analysis, chi-square and Logistic regression analysis. Results : 1.The adolescents who have parents with college degree are 70% higher of dental services utilization than the adolescents counterpart(whose parents don't have degrees). And also the adolescents living in cities are 1.3 times higher use of dental services than others living in countries. 2. In case of drinking soda, students having soda 4 days per week on average are 1.2 times higher use of dental services than who don't. 3.The students brushing teeth after lunch are 0.9 times lower use of dental service than who don't. And the students who have tooth ache whenever they have a meal are 1.6 times higher use of dental service than the students who don't have tooth ache. The students who had a dental health education are 1.4 times higher utilization of dental service than who don't. The difference of using dental service between the students who have gum disease and halitosis and the students who don't is almost none. 4. The students who drink alcohol and smoke 10 days more or less a month are 0.8 ~ 0.9 times lower use of dental service than who don't. Conclusions : The rate of utilizing dental service is higher at students who live with parents having college degrees and the more have oral health behavior, the less use of dental service for treatment. We concluded that more educational program should be developed and vitalized so that students can have oral health.