• Parasites, Hosts and Diseases
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• v.44 no.2 s.138
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• pp.101-116
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• 2006

Vaginal trichomoniasis, caused by Trichomonas vaginalis, is the most common sexually transmitted disease. More than 170 million people worldwide are annually infected by this protozoan. In the Republic of Korea, 10.4% of women complaining of vaginal symptoms and signs were found to be infected with T. vagina/is. However, despite its high prevalence, the pathogenesis of T. vaginalis infection has not been clearly characterized although neutrophil infiltration is considered to be primarily responsible for the cytologic changes associated with this infection. We hypothesized that trichomonads in the vagina sometime after an acute infection secrete proteins like excretory-secretory product that have a chemotactic effect on neutrophils, and that these neutrophils are further stimulated by T. vaginalis to produce chemokines like IL-8 and $GRO-\alpha$, which further promote neutrophil recruitment and chemotaxis. Thus, neutrophil accumulation is believed to maintain or aggravate inflammation. However, enhanced neutrophil apoptosis induced by live T. vaginalis could contribute to resolution of inflammation. Macrophages may constitute an important component of host defense against T. vaginalis infection. For example, mouse macrophages alone and those activated by lymphokines or nitric oxide are known to be involved in the extracellular killing of T. vaginalis. In the host, T. vaginalis uses a capping phenomenon to cleave host immunoglobulins with proteinases and thus escape from host immune responses. Recently, we developed a highly sensitive and specific diagnostic polymerase chain reaction (PCR) technique using primers based on a repetitive sequence cloned from T. vaginalis (TV-E650), and found that the method enables the detection of T. vaginalis at concentrations as low as 1 cell per PCR mixture.

• Journal of Life Science
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• v.23 no.2
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• pp.306-310
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• 2013

We compared the efficacy of the competitive ELISA method for measuring the level of urinary aflatoxin M1 (AFM1) with that of the HPLC-fluorescence detector (HPLC-FLD) method. The recovery rate of AFM1 with the ELISA method was 105% (73-124%), and the coefficient of variation of the analysis was 6.85%. The ELISA method showed a 0.20 pg/ml and 0.62 pg/ml limit of detection and limit of quantitation, respectively. In correlation analysis, the two methods showed a very strong and statistically significant correlation (R=0.96, p<0.01). However, in spite of the strong correlation, the ELISA method tended to overestimate the urinary AFM1 concentration compared to the HPLC-FLD method. These results suggest that the competitive ELISA method may be a useful technique for measuring the AFM1 level in high-throughput urine samples, but it needs to be corrected with a regression equation from regression analysis with the HPLC-FLD method.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.3
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• pp.598-607
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• 1992

The environment degradation of structural steel under high temperature is one of the key phenomena governing the availability and life of plant. This degradation resulted from the microstructural changes due to the long exposure at high temperature affect the mechanical properties such as creep strength and toughness. For instance, boiler tube materials usually tend to degrade, after long term operation, by precipitates, spherodizing, coarsening, and change in chemical composition of carbides. In this study, the material degradation under high temperature exposure was investigated by evaluating the carbide precipitation. The electrochemical polarization method was facilitated to investigate the precipitation and coarsening of carbides. It was shown by the modified electrochemical potentiokinetic reactivation (EPR) tests that the passivation of Mo-rich carbides did not occur even in the anodic peak current (Ip) which indicates the precipitation of Mo$_{6}$C was also observed. And it was assured that special electrolytic cell assembled in this research can be used for the detection of Mo$_{6}$C precipitation in the field.eld.

• Journal of the Korean Society for Nondestructive Testing
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• v.22 no.1
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• pp.32-37
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• 2002

The presence of hydrogen in industrial plants is a source of damage. Hydrogen attack is one such form of degradation and often causing large tube ruptures that necessitate an immediate shutdown. Hydrogen attack may reduce the fracture toughness as well as the strength of steels. This reduction is caused partially by the presence of cavities and microcracks at the grain boundaries. In the past several techniques have been used with limited results. This paper describes the application of an ultrasonic velocity and attenuation in hydrogen damage. Ultrasonic tests showed a decrease in wave velocity and an increase in attenuation. Such results demonstrate the potential for ultrasonic nondestructive testing to quantify damage. Based on this study, reliable recommendation is suggested to detect hydrogen attack.

• Journal of the Korean Society for Nondestructive Testing
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• v.22 no.1
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• pp.14-21
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• 2002

The development of a new experimental method is required to easily observe the growth behavior of fatigue cracks. To satisfy the requirement, an image processing technique was introduced to fatigue testing. The length of surface fatigue crack could be successfully measured by the image processing system. At first, the image data of cracks were stored into the computer while the cyclic loading was interrupted. After testing, crack length was determined using an image processing software which was developed by authors. Various image processing techniques like a block matching method was applied tc the detection of surface fatigue cracks. By comparing the data measured by the image processing system with those by the manual measurement with a microscope, the effectiveness of the image processing system was established. If the proposed method is used to monitor and observe the crack growth behavior automatically, the time and efforts for fatigue test could be dramatically reduced.

• Journal of the Korean Society for Nondestructive Testing
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• v.19 no.3
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• pp.173-179
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• 1999

The defects on the metal surface. such as the ended circular pressed hole. the penetrated circular drilled hole, and the linear hollow lanes have been investigated by means of the microwave. In this experiment, frequency was set at 9.2GHz with 3kHz modulation, and the methods of reflection, transmission, fixed carrier frequency, and mod-demodulated technique have been used for investigating defects. The magnitudes of the microwave signals have been changed at the ended circular pressed hole and the penetrated circular drilled hole. The defect sizes that were estimated from the reflected microwave signals had the dimensions enlarged by twice the original size of the penetrated circular drilled hole and 2.5 times the original size of the ended circular pressed hole. The magnitudes of the reflected microwave signals from the linear hollow lane have increased with expansion of the width of the notch. In the linear hollow lane with the depth of 2.4mm, the reflected microwave signals versus the defect widths had a maximum value at the defect width of 50mm, and in the linear hollow lanes with the depths of 1.2mm and 0.45mm, the reflected microwave signals versus the defects widths had the maximum values each at the defect depths of 55mm.

• Journal of the Korean Society for Nondestructive Testing
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• v.24 no.4
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• pp.307-314
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• 2004

A circumferential guided wave method was developed to detect the axial crack on the bent feeder pipe. Dispersion curves of circumferential guided waves were calculated as a function of curvature of the pipe. In the case of thin plate, i.e. infinite curvature, as the frequency increases, the $S_0$ and $A_0$ mode coincide and eventually become Rayleigh wave mode. In the case of pipe, however, as the curvature increases, the lowest modes do not coincide even in the high frequencies. Based on the analysis, a rocking technique using angle beam transducer was applied to detect an axial defect in the bent region of PHWR feeder pipe. Based on the analysis of experimenal data for artificial notches, the vibration modes of each signal were identified. It was found that the notches with the depth of )0% of wall thickness can be detected with the method.

• Journal of Internet Computing and Services
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• v.16 no.5
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• pp.1-9
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• 2015

As attacks in cyber space become advanced and complex, monotonous defense approach of one-one matching manner between attack and defense may be limited to defend them. More efficient defense method is required. This paper proposes multi layers security scheme that can support to defend assets against diverse cyber attacks in systematical and adaptive. We model multi layers security scheme based on Defense Zone including several defense layers and also discuss essential technical elements necessary to realize multi layers security scheme such as cyber threats analysis and automated assignment of defense techniques. Also effects of multi layers security scheme and its applicability are explained. In future, for embodiment of multi layers security scheme, researches about detailed architecture design for Defense Zone, automated method to select the best defense technique against attack and modeling normal state of asset for attack detection are needed.

• Journal of Korea Multimedia Society
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• v.12 no.8
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• pp.1073-1081
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• 2009

In this paper, we proposed new method to enhance choroidal vessels by suppressing retina vessels brightness. It is well-known that CNV(choroidal neovascularization) is related with sight loss. The main feature of CNV is the occurrence of new vessels in choroid. Unfortunately, because retina vessels brightness is stronger than choroidal vessels brightness in ICGA(indocynanine green angiography) image, so that the choroidal vessels were hardly recognized. Therefore, for correct diagnosis, the choroidal vessels must be enhanced in ICGA image. The proposed enhancement method consists of 3 strategies. First, the retina vessels were detected by multi scale enhancement technique, hysteresis thresholding, KNN(Kth-nearest neighbor) classification method. And then, a retina vessel mask was generated from detection result. Next, the brightness of retina vessels was suppressed by the proposed conditional region erosion method and mask region until the mask region was vanished. Finally, the brightness of choroidal vessel was enhanced on processed image. Through an experiment, we had confirmed that the proposed method was robust and efficient.

• Journal of Korean Neurosurgical Society
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• v.30 no.2
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• pp.186-193
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• 2001

Objectives : Trigeminal neuralgia and hemifacial spasm are caused by vascular compression of the REZ(root entry or exit zone) of the 5th and the 7th cranial nerve. Preoperative detection of neurovascular compression is essential for accurate diagnosis, appropriate treatment, and the good operative results. Three dimensional Fourier Transformation-Constructive Interference in Steady State(3DFT-CISS) images are known to give good contrast between CSF, nerve, and vessels. We applied a 3DFT-CISS imaging technique for the preoperative evaluation of patients with these diseases and estimated the diagnostic accuracy and usefulness of this study. Methods : A series of 71 patients with trigeminal neuralgia and hemifacial spasm were treated by microvascular decompression. Among them 34 patients with trigeminal neuralgia and 24 patients with hemifacial spasm had preoperative CISS images. We compared the radiologic finding with the operative finding, and analysed the diagnostic usefulness of 3DFT-CISS imaging. Results : The sensitivity of CISS images of detecting the neurovascular compression was 90.3% in trigeminal neuralgia and 100% in hemifacial spasm. There were one false-positive and three false-negative cases in trigeminal neuralgia, and one false-positive case in hemifacial spasm. The accuracy in diagnosing the causative vessel was 73.5% in trigeminal neuralgia and 83.3% in hemifacial spasm. Conclusion : CISS image is very useful diagnostic tool for preoperative evaluation of neurovascular compression in patients with trigeminal neuralgia and hemifacial spasm. No additional neuroradiologic examination other than CISS image and MRA is needed for preoperative evaluation of patients with trigeminal neuralgia and hemifacial spasm.