• Advances in Computational Design
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• v.5 no.1
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• pp.1-11
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• 2020

Soil is the fundamental element in the construction process. Soil problems affect the safety of the structures, even so the high quality of the structures and so, bad soil found the structures will affect the lifetime or even destroy the structures built on it. Therefore, the study of soil is an important step in the construction process and the investigation of the most effective characteristics of a special kind of soil (shale soil), i.e. Atterberg limits, swelling pressure, swelling potential and unconfined compression strength, are the most effective soil properties. A big projects will be constructed in new urban extension areas with expansive shale soils, like at Al-Kawamil and new Akhmim shale soils which associated with soil problems, treatment system should be used to ensure the stability of the soil under the structures foundations one of the most effective methods is by adding lime solution to the soil by specific quantities, which affect on the properties of the shale soil by decreasing the swelling and increasing the compressive strength of the treatment soils. Experimenting with the soil added to the lime, it was found that the addition of lime solution 6% improve c j the properties of the soil. The results of the tests showed the high effectiveness of using lime in the treatment of Al-Kawamil soil

• (The) Research of the performance art and culture
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• no.32
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• pp.333-370
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• 2016

This study examines self-reflexive scenes of Changgeuk [창극; Korean classical opera] Seopyenje [서편제]. This show deals with Pansori [판소리; a kind of Korean folk play] and its singers. The uniqueness of this show is that although it is a new creative work of Changgeuk, the traditional Pansori music is used intactly. These characteristics are related to some self-reflexive scenes in the show: the narcissistic reference of Pansori makes to seem that this show inherits a artistry of Pansori; a play within a play and a role-play reinforce a reality on the action and characters of outer play; an intertextuality, bringing the narrative and music of Pansori Simcheong-ga [심청가] in this show, it makes audiences spontaneously discover a connection between the cited original text and the hypertext. Namely, the self-reflexivity of Changgeuk Seopyenje doesn't destroy an illusion, but rather it presents a kind of conservative self-reflexivity which uncovers a part of tricks for the illusion in order to create new illusion.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.171-181
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• 2019

In this article, we examined designer babies and bioethics, and we reviewed how Anna argued that she had the rights to her body through trial with parents. No matter what purpose a cloned human or designer baby was born with, it is worth being respected as the birth itself. After learning the secrets of his birth in Jodie Picoult's My Sister's Keeper, which is based on a designer baby, Anna falls into confusion of identity and sues parents who decide to transplant organs regardless of Anna's will. Anna argues that she has the right to make decisions about her own body and that even her parents can't disregard her opinions. Scientists should stop their research if using biotechnology to reproduce humans, such as designer babies and cloned humans, can destroy the natural order.

• Journal of Veterinary Science
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• v.22 no.1
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• pp.4.1-4.13
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• 2021

Background: Microsporum canis is a zoonotic disease that can cause dermatophytosis in animals and humans. Objectives: In clinical practice, ketoconazole (KTZ) and other imidazole drugs are commonly used to treat M. canis infection, but its molecular mechanism is not completely understood. The antifungal mechanism of KTZ needs to be studied in detail. Methods: In this study, one strain of fungi was isolated from a canine suffering with clinical dermatosis and confirmed as M. canis by morphological observation and sequencing analysis. The clinically isolated M. canis was treated with KTZ and transcriptome sequencing was performed to identify differentially expressed genes in M. canis exposed to KTZ compared with those unexposed thereto. Results: At half-inhibitory concentration (½MIC), compared with the control group, 453 genes were significantly up-regulated and 326 genes were significantly down-regulated (p < 0.05). Quantitative reverse transcription polymerase chain reaction analysis verified the transcriptome results of RNA sequencing. Gene ontology enrichment analysis and Kyoto Encyclopedia of Genes and Genomes enrichment analysis revealed that the 3 pathways of RNA polymerase, steroid biosynthesis, and ribosome biogenesis in eukaryotes are closely related to the antifungal mechanism of KTZ. Conclusions: The results indicated that KTZ may change cell membrane permeability, destroy the cell wall, and inhibit mitosis and transcriptional regulation through CYP51, SQL, ERG6, ATM, ABCB1, SC, KER33, RPA1, and RNP genes in the 3 pathways. This study provides a new theoretical basis for the effective control of M. canis infection and the effect of KTZ on fungi.

• Journal of Applied Biological Chemistry
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• v.64 no.4
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• pp.369-374
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• 2021

Brown blotch disease of oyster mushrooms is caused by tolaasin and its analog peptide toxins which are produced by Pseudomonas tolaasii. Tolaasin peptides form pores in the plasma membrane and destroy the fruiting body structure of mushroom. Lysis of red blood cells, hemolysis, can be occurred by cytotoxic activity of tolaasin. The hemolytic activity of tolaasin is inhibited by metal ions, such as Zn²⁺ and Ni²⁺. When Gadolinium ion was added, a biphasic effect was observed on tolaasin-induced hemolysis, an increase in hemolysis at submillimolar concentrations and an inhibition at millimolar concentrations. The mechanism of gadolinium ion-induced inhibition of tolaasin activity may not be similar to those of the inhibitions by other metal ions. Since gadolinium ion has been reported to change a lateral pressure of lipid membrane by binding to the negative charges of membrane lipids, it may not directly work on the tolaasin channel gating, but rather decrease the stability of tolaasin channel by increasing firmness of membrane.

• Animal Bioscience
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• v.34 no.9
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• pp.1525-1531
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• 2021

Objective: The objective of this study was to evaluate the antimicrobial effects of fermented Maillard reaction products made by milk proteins (FMRPs) on Clostridium perfringens (C. perfringens), and to elucidate antimicrobial modes of FMRPs on the bacteria, using physiological and morphological analyses. Methods: Antimicrobial effects of FMRPs (whey protein plus galactose fermented by Lactobacillus rhamnosus [L. rhamnosus] 4B15 [Gal-4B15] or Lactobacillus gasseri 4M13 [Gal-4M13], and whey protein plus glucose fermented by L. rhamnosus 4B15 [Glc-4B15] or L. gasseri 4M13 [Glc-4M13]) on C. perfringens were tested by examining growth responses of the pathogen. Iron chelation activity analysis, propidium iodide uptake assay, and morphological analysis with field emission scanning electron microscope (FE-SEM) were conducted to elucidate the modes of antimicrobial activities of FMRPs. Results: When C. perfringens were exposed to the FMRPs, C. perfringens cell counts were decreased (p<0.05) by the all tested FMRPs; iron chelation activities by FMRPs, except for Glc-4M13. Propidium iodide uptake assay indicate that bacterial cellular damage increased in all FMRPs-treated C. perfringens, and it was observed by FE-SEM. Conclusion: These results indicate that the FMRPs can destroy C. perfringens by iron chelation and cell membrane damage. Thus, it could be used in dairy products, and controlling intestinal C. perfringens.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.6
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• pp.1155-1160
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• 2018

Presently in 2018, the security market is requiring progressive development and innovation in the area of security on account of new changes and technologies. This means the rapid and prompt development of the service platforms and service-based information systems. Here, this study is going to examine the process of operating a number of services and obtaining security, not the criteria for selecting particular service in online environment where the various services exist. Within a series of flows to protect the manager's authority about the platforms operated by information systems, and to provide and destroy services, this author limits the entire service platforms of the optimized balance module into four categories maximum for the security of the area apt for illegal invasion and access, and the proper area. Also, about the area with limited security, this researcher again applies subordinate security policy and technology respectively. This author here will suggest a method to provide and to extend safety and security for the information system and also propose the process of applying it as well.

• Korean journal of applied entomology
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• v.58 no.3
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• pp.189-196
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• 2019

While the darkling beetle, Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae) is considered a pest of stored products, it does not pose a significant economic threat to this industry. The grains these beetles feeding on are often already damaged. However, the beetle is now being treated as the foremost premise pest in the poultry industry in many countries of the world. Recently, the darkling beetle has also infested in broiler chicken houses of Korea. The problems caused by this pest destroy the insulate facilities of poultry houses, reduce chick's overall performance, transmit pathogenic organisms, and have been leading to substantial economic losses for poultry producers. Therefore, we conducted surveys on the status of infestation and damage of this pest in broiler chicken houses. Because there is no simple one step process that will completely eliminate darkling beetle populations from broiler facilities, we would like to outline further studies on the proper control measures.

• Journal of Marine Bioscience and Biotechnology
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• v.10 no.2
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• pp.91-96
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• 2018

There are many eutrophic lakes by point and non-point pollution sources such as in dustrial waste water, domestic raw sewage, and mucks. The eutrophic lakes not only cause algal blooms but also destroy the ecosystem in the lakes due to high nutrient concentrations. The purpose of this study was to improve water quality in eutrophic lakes by cultivating microalgae using photobioreactors (PBRs) with selectively permeable mesh (SPM), supplying nutrients in the lake and inhibiting cell leakage by diffusion and water permeability. Chlorella vulgaris, was cultivated using PBRs with SPM installed in Inkyung Lake located in Inha university, Incheon, Korea. When cultivating C. vulgaris, $8.3g/m^2/day$ of average biomass productivity was obtained at 3 days. Furthermore, concentrations of total nitrogen and phosphorus were reduced by 35.7% and 84.2%, respectively, compared to initial condition and water quality in eutrophic lake was improved to oligotrophic environment. These results suggest that microalgal cultivation using PBRs with SPM in the lake could produce microalgal biomass as well as improve water quality by decreasing nutrient concentrations.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.3
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• pp.1502-1522
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• 2019

Leakage of secret keys may be the most devastating problem in public key cryptosystems because it means that all security guarantees are missing. The forward security mechanism allows users to update secret keys frequently without updating public keys. Meanwhile, it ensures that an attacker is unable to derive a user's secret keys for any past time, even if it compromises the user's current secret key. Therefore, it offers an effective cryptographic approach to address the private key leakage problem. As an extension of the forward security mechanism in certificate-based public key cryptography, forward-secure certificate-based signature (FS-CBS) has many appealing merits, such as no key escrow, no secure channel and implicit authentication. Until now, there is only one FS-CBS scheme that does not employ the random oracles. Unfortunately, our cryptanalysis indicates that the scheme is subject to the security vulnerability due to the existential forgery attack from the malicious CA. Our attack demonstrates that a CA can destroy its existential unforgeability by implanting trapdoors in system parameters without knowing the target user's secret key. Therefore, it is fair to say that to design a FS-CBS scheme secure against malicious CAs without lying random oracles is still an unsolved issue. To address this problem, we put forward an enhanced FS-CBS scheme without random oracles. Our FS-CBS scheme not only fixes the security weakness in the original scheme, but also significantly optimizes the scheme efficiency. In the standard model, we formally prove its security under the complexity assumption of the square computational Diffie-Hellman problem. In addition, the comparison with the original FS-CBS scheme shows that our scheme offers stronger security guarantee and enjoys better performance.