• Journal of the Korean Operations Research and Management Science Society
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• v.21 no.3
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• pp.127-141
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• 1996

In this paper, we propose a 7-phase life cycle model which applies to Computer Integrated Manufacturing systems. The model emphasizes product design and manufacturing design activities of CIM to secure the critical success factors of CIM systems such as high quality, adaptability, productivity, and flexibility. It is argued that the product design aspect would be divided into three phases-conceptual design, embodiment design, and detialed design. The conceptual design phase is to build a conceptual model of the product based on requirements and specifications which reflect "the voice of the customer". THe embodiment design phase utilizes specific design tools such as DFM, CAE, and CAD, and results in a concrete model of the product and parts. The detailed design phase is to crete a working prototype of the product and design tools such as DFA. CAD and CAM are employed in this phase. The output of the product design activity is to be the input for the manufacturing design activity. Using the proposed model, one can effectively and efficiently manufacture a high-quality, low-cost product with short delivery time, and above all achieve customer'ssatisfaction.isfaction.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.9
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• pp.1408-1414
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• 2004

The use of flip-chip technology has many advantages over other approaches for high-density electronic packaging. ACF (anisotropic conductive film) is one of the major flip-chip technologies, which has short chip-to-chip interconnection length, high productivity, and miniaturization of package. In this study, thermal fatigue lift of ACF bonding flip-chip package has been predicted. Elastic and thermal properties of ACF were measured by using DMA and TMA. Temperature dependent nonlinear hi-thermal analysis was conducted and the result was compared with Moire interferometer experiment. Calculated displacement field was well matched with experimental result. Thermal fatigue analysis was also conducted. The maximum shear strain occurs at the outmost located bump. Shear stress-strain curve was obtained to calculate fatigue life. Fatigue model for electronic adhesives was used to predict thermal fatigue life of ACF bonding flip-chip packaging. DOE (Design of Experiment) technique was used to find important design factors. The results show that PCB CTE (Coefficient of Thermal Expansion) and elastic modulus of ACF material are important material parameters. And as important design parameters, chip width, bump pitch and bump width were chose. 2$^{nd}$ DOE was conducted to obtain RSM equation far the choose 3 design parameter. The coefficient of determination ($R^2$) for the calculated RSM equation is 0.99934. Optimum design is conducted using the RSM equation. MMFD (Modified Method for feasible Direction) algorithm is used to optimum design. The optimum value for chip width, bump pitch and bump width were 7.87mm, 430$\mu$m, and 78$\mu$m, respectively. Approximately, 1400 cycles have been expected under optimum conditions. Reliability analysis was conducted to find out guideline for control range of design parameter. Sigma value was calculated with changing standard deviation of design variable. To acquire 6 sigma level thermal fatigue reliability, the Std. Deviation of design parameter should be controlled within 3% of average value.

• Journal of the Korean housing association
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• v.27 no.1
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• pp.63-70
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• 2016

Domestic apartment housing has been designed in accordance with the new housing supply-driven policies for a long time. As a result, its design, material production, construction, maintenance and remodeling process, rather than being systematically performed, were individually approached to cause insufficient linkage between technologies. For these problems and the supply of long life housing, active research on long life housing has been conducted in Korea since 2005. However, the existing research on long life housing has been focused on a single item with no connection made between infill systems, and no overall interface rule, resulting in no activation of the business. In this study, for the supply and activation of long life housing, we aim to analyze the problems of existing long life housing to set up its matching standards for infill systems.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.46-49
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• 2004

The spider of a drum washing machine receives the repeated fatigue loadings during laundering. Although the spider is designed statically safely, it often happens fatigue failure. Therefore it requires the safe design for fatigue and needs the prediction of quantitative fatigue life. The S-N diagram for a spider material is developed by fatigue test and statistical analysis. The stresses are measured directly from strain gages on the spider. To predict the fatigue life of spider, the rainflow counting method and Miner's rule are used. The data for fatigue life are analyzed statistically. From these data, reliability estimation for fatigue life can be done and also, equivalent fatigue life can be obtained. It will be applied to make and improve to a short period for design and prototype test.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2006.04a
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• pp.549-556
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• 2006

Life cycle cost is one of important factors in the evaluation of economy feasibility. Load carrying capacity curves for girders and decks are derived on the basis of bridge diagnostic results and condition grade curves to determine the service life and life cycle profile. The total life cycle costs including initial cost, damage cost, maintenance cost, user cost, and etc for the service life are calculated for steel box girder, PSC-I girder and rationalized plate girder. The optimal designs are performed for various service lifes and different superstructure types. The effects of parameters on the life cycle cost are investigated and the economy feasibility is evaluated through the sensitivity analysis.

• Transactions of the Korean Society of Automotive Engineers
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• v.7 no.5
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• pp.213-220
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• 1999

The life data analysis of the system and component are useful to describe the result of reliability test in product life to satisfy customer's growing need and to change test specifications or design criteria by life data analysis. And vehicle durability tesr occurred market environment. In this study, a statistical analysis for the wear life of brake pad linings helped perform correlation procedure between vehicle durability test and market. B-life values of the brake pad wear life data from both vehicle durability test and marker usage were compared to determine acceleration of the test by the Weibull, normal and log-normal distribution. The acceleration coefficient of the vehicle durability test can access to evaluate design criteria of product and test specification.

• Journal of Advanced Marine Engineering and Technology
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• v.29 no.2
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• pp.202-208
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• 2005

Stress and fatigue life analyses are performed to enhance a fatigue life of a heating drum of the roller press for medium density fiberboard. The finite element method employing the submodel is used to analyze stress concentration in the journal of the heating drum. The fatigue life is evaluated by the stress-life theory. Two modified designs of the journal are suggested and evaluated to reduce the maximum stress and to increase the fatigue life Their structural reliabilities are verified in terms of the yield strength and the design life.

• Corrosion Science and Technology
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• v.3 no.2
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• pp.72-80
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• 2004

Recently, the demand on the practical application of life-cycle cost effective design and rehabilitation of bridges is rapidly growing in civil engineering practice. However, in spite of impressive progress in the researches on the Life-Cycle Cost (LCC), the most researches have only focused on the theoretical point but did not fully incorporate the critical issues for the practical implementation. Thus, this paper is intended to suggest a systemic integrated approach to the practical application of various LCC methodologies for the design and rehabilitation of bridges, For that purpose, hierarchical definitions of LCC models are presented to categorize the approach of LCC assessment applicable for the practical implementation. And then, an integrated LCC system model is introduced with an emphasis on data uncertainty assessment and user-friendly knowledge-based database for its successful implementation. Finally, in order to demonstrate the LCC effectiveness for design and rehabilitation of real bridge structures, illustrative examples are discussed.

• Journal of the Korean Society of Clothing and Textiles
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• v.42 no.2
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• pp.298-310
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• 2018

This study examines how to improve clothes according to types of disability and classify related studies. The study method used a literature review along with studies conducted after 2000. According to the results, the types of disability causing difficulty in terms of clothing habits are limb disorders and sensory defects among the types of physical disability. The results of the quantitative measurement on studies indicated that the number of studies increased almost twice as much before 2000. Particularly with the development of new technology and fashion trends, the number of studies on design increased. The topics of studies are found in design development, construction for disabled, and understanding clothing life. The design development topic is about suggesting functional designs that can protect the human body or aid in the use of rehabilitation devices. The construction topic for the disabled is to improve the inconvenience of wearing clothes, particularly for those with limb disorders. Lastly, the topic of examining clothing life is about using new technology to provide individuals with sensory defects with information about clothing life or the current status of the clothing market for the disabled.

• BMB Reports
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• v.42 no.5
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• pp.260-264
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• 2009

Tumor necrosis factor-$\alpha$ (TNF-$\alpha$) exhibits cytotoxicity towards various tumor cells in vitro and induces apoptotic necrosis in transplanted tumors in vivo. It also shows severe toxicity when used systemically for the treatment of cancer patients, hampering the development of TNF-$\alpha$ as a potential anticancer drug. In order to understand the structure-function relation of TNF-$\alpha$ with respect to receptor binding, we selected four regions on the bottom of the TNF-$\alpha$ trimer that are in close contact with the receptor and carried out mutagenesis studies and computational modeling. From the study, various TNF-$\alpha$ muteins with a high therapeutic index were identified. These results will provide a structural basis for the design of highly potent TNF-$\alpha$ for therapeutic purposes. By conjugating TNF-$\alpha$ muteins with a high therapeutic index to a fusion partner, which targets a marker of angiogenesis, it could be possible to develop TNF-$\alpha$ based anticancer drugs.