• Journal of Photoscience
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• 제8권2호
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• pp.83-86
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• 2001

Structural analyses of oligosaccharide-malononitrile derivatives were conducted by matrix-assisted laser desorption/ionization post-source decay (MALDI-PSD) analysis in positive ion mode. The malononitrile derivatives of oligosaccharides, which were developed for highly sensitive detection of multi-component oligosaccharides by negative ion electrospray ionization mass spectrometry (ESI MS), were detected by positive-ion MALDI with the detection limit of 2 pmol level from the crude derivatization sample. The used matrix affected drastically the analytical results of oligosaccharide-malononitrile derivative by matrix-assisted laser desoprtion/ionization mass spectrometry (MALDI MS). The malononitrile derivatization of oligosaccharide also affect the patterns of MALDI-PSD spectra and give much more structural information than the free oligosaccharide.

• The Journal of the Acoustical Society of Korea
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• 제18권1E호
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• pp.37-43
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• 1999

This paper deals with a hybrid finite element method for wave scattering problems in infinite domains. Scattering of waves involving complex geometries, in conjunction with infinite domains is modeled by introducing a mathematical boundary within which a finite element representation is employed. On the mathematical boundary, the finite element representation is matched with a known analytical solution in the infinite domain in terms of fields and their derivatives. The derivative continuity is implemented by using a slope constraint. Drilling degrees of freedom at each node of the finite element model are introduced to make the numerical model more sensitive to the transverse component of the elastodynamic field. To verify the effects of drilling degrees freedom and slope constraints individually, reflection of normally incident P and SV waves on a traction free half spaces is considered. For the P-wave incidence, the results indicate that the use of slope constraint is more effective because it suppresses artificial reflection at the mathematical boundary. For the SV-wave case, the use of drilling degrees freedom is more effective by reducing numerical error at irregular frequencies.

• Journal of applied mathematics & informatics
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• 제23권1_2호
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• pp.269-279
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• 2007

This paper describes a direct search method for a class of linearly constrained optimization problem. Through research we find it can be treated as an unconstrained optimization problem. And with the decrease of dimension of the variables need to be computed in the algorithms, the implementation of convergence to KKT points will be simplified to some extent. Convergence is shown under mild conditions which allow successive frames to be rotated, translated, and scaled relative to one another.

• Structural Monitoring and Maintenance
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• 제10권1호
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• pp.63-86
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• 2023

Structural health monitoring and damage detection are essential for assessing, maintaining, and rehabilitating structures. Most of the existing damage detection approaches compare the current state structural response with the undamaged vibrational structural response, which is unsuitable for old and existing structures where undamaged vibrational responses are absent. One of the approaches for existing structures, numerical model updating/inverse modelling, available in the literature, is limited to numerical studies with high-end software. In this study, an attempt is made to study the effectiveness of the model updating technique, simplify modelling complexity, and economize its usability. The optimization-based detection problem is addressed by using programmable open-sourced code, OpenSees^® and a derivative-free optimization code, NOMAD^®. Modal analysis is used for damage identification of beam-like structures with several damage scenarios. The performance of the proposed methodology is validated both numerically and experimentally. The proposed method performs satisfactorily in identifying both locations and intensity of damage in structures.

• Structural Engineering and Mechanics
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• 제86권3호
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• pp.291-309
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• 2023

This paper addresses the finite element modeling of functionally graded porous (FGP) beams for free vibration and buckling behaviour cases. The formulated finite element is based on simple and efficient higher order shear deformation theory. The key feature of this formulation is that it deals with Euler-Bernoulli beam theory with only three unknowns without requiring any shear correction factor. In fact, the presented two-noded beam element has three degrees of freedom per node, and the discrete model guarantees the interelement continuity by using both C⁰ and C¹ continuities for the displacement field and its first derivative shape functions, respectively. The weak form of the governing equations is obtained from the Hamilton principle of FGP beams to generate the elementary stiffness, geometric, and mass matrices. By deploying the isoparametric coordinate system, the derived elementary matrices are computed using the Gauss quadrature rule. To overcome the shear-locking phenomenon, the reduced integration technique is used for the shear strain energy. Furthermore, the effect of porosity distribution patterns on the free vibration and buckling behaviours of porous functionally graded beams in various parameters is investigated. The obtained results extend and improve those predicted previously by alternative existing theories, in which significant parameters such as material distribution, geometrical configuration, boundary conditions, and porosity distributions are considered and discussed in detailed numerical comparisons. Determining the impacts of these parameters on natural frequencies and critical buckling loads play an essential role in the manufacturing process of such materials and their related mechanical modeling in aerospace, nuclear, civil, and other structures.

• Journal of Microbiology and Biotechnology
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• 제25권10호
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• pp.1614-1620
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• 2015

Plasmid-cured derivative strains of Bacillus anthracis are frequently used in laboratory studies. Plasmid incompatibility, which does not increase the risk of chromosomal mutation, is a useful method for plasmid curing. However, in bacteria containing multiple plasmids, it often requires the sequential introduction of multiple, specific incompatibility plasmids. This lengthy process renders the traditional plasmid incompatibility method inefficient and mutation-prone. In this study, we successfully cured plasmids pXO1 and pXO2 from B. anthracis A16 simultaneously using only one recombinant incompatible plasmid, pKORT, to obtain a plasmid-free strain, designated A16DD. This method may also be useful for the simultaneous, one-step curing of multiple plasmids from other bacteria, including Bacillus thuringiensis and Yersinia pestis.

• 한국전산구조공학회논문집
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• 제19권4호
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• pp.441-447
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• 2006

이 논문은 구조해석에서 수치미분의 적용성에 관한 연구이다. 구조물 선형식의 미분은 구조물의 거동해석에서 반드시 필요한 수학적 계산 중의 하나이다. 아치와 같이 구조물의 선형식이 곡선인 경우에 미분식의 산출은 많은 시간과 노력을 필요로 한다. 이 연구에서는 구조해석에서 수치미분의 적용성을 아치의 자유진동 문제를 통하여 검증하였다. 전진 5차다항식으로부터 아치 곡률항의 미분값을 계산하고 이를 대수적으로 구한 곡률항과 비교하였다 이렇게 얻은 곡률항을 이용하여 최종적으로 산출한 아치의 고유진동수는 문헌해와 아주 우수하게 근접하였다. 이러한 결과로부터 구조해석에서 수치미분의 적용성과 그 결과의 정확성을 입증할 수 있었다.

• 융합신호처리학회논문지
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• 제15권1호
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• pp.9-14
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• 2014

이동 통신망의 기지국과 이동국 사이의 거리 차로 인하여 발생하는 경로 손실 데이터를 분석하였다. 본 논문에서는, 측정된 수신 신호세기(RSSI)로부터 송수신기 거리 차이에 따른 경로 손실을 계산하여 이를 그래프로 표시하고, 평균한 데이터를 이용하여 기존의 경로 손실 모델들(자유공간 모델, 지면반사파 모델, 하타 모델, ${\ldots}$)과 그래프를 동시에 그려서 비교하였다. 2 Km, 1 Km, 0.5 Km 간격으로 평균한 경로 손실 데이터에 대한 표준 편차를 구해 보니, 각각 2.29 dB, 3.39 dB, 4.75 dB가 되었다. 본 논문에서는 거리별로 계산된 경로 손실 평균값들의 미분 값을 구하여, 앞에서 구한 경로 손실 표준 편차의 1 또는 2배수를 초과하여 변동하는 위치를 찾아내는 방법을 제안 하였다. 이렇게 제안한 방법을 적용하여 분석한 결과, 송수신기 사이에서 손실이 급격하게 발생하는 지점이, 2 Km 간격으로 경로 손실을 평균한 경우에는 5 지점, 1 Km 간격으로 평균한 경우에는 7 지점, 0.5 Km 간격으로 평균한 경우에는 19 지점이 됨을 알 수 있었고, 구체적인 위치를 파악하는 성과를 얻었다.

• Journal of Pharmaceutical Investigation
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• 제20권2호
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• pp.55-64
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• 1990

Soybean fatty acid, the largest byproduct in the production of soybean oil, was formulated for hand cream, oil in water emulsion base, to improve the suppleness and elasticity of skin. The stability of emulsion observed by a macroscopic method was used as a characteristic index for deciding an optimum formula of hand creams. The optimum formula of the most stable hand cream was obtained from polynomial regression equation, contour graphs and partial derivative graphs. The values of soybean fatty acid and stearyl alcohol in the obtained optimum formula were 9.75 and 14.75 w/w%, respectively, and sodium lauryl sulfate was not needed. Experimental value for the stability of hand cream prepared according to the optimum formula was 76,14 days, and the prediction value by computation method was 73.25 days. From the results of accelerated tests by elevated temperature, the stability of hand cream by optimum formula was 1.7 year at room temperature $(25^{\circ}C)$. The hand cream containing soybean fatty acid was found to be free of primary irritant substance to the skin by Draize technique.

• 한국정밀공학회지
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• 제13권11호
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• pp.132-142
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• 1996

This paper presents a technique to model and control a manipulator which has a flexible link and moves in a vertical plane. The flexible link is modeled as an Euler-Bernoulli Beam. Elastic deformation of the flexible link is represented using the assumed modes method. A comparison function which satisfies all geometric and natural boundary conditions of a cantilever beam with an end mass is used as an assumed mode shape. Lagrange's equation is utilized for the development of a discretized model. This paper presents a simple technique to improve the correctness of the developed model. The final model including the shortening effect due to elastic deformation correlates very well with experimental results. The free body motion simulation shows that two assumed modes for the representation of the elastic deformation is proper in terms of the model size and correctness. A control algorithm is developed using PID control technique. The proportional, integral and derivative control gains are determined based on dominant pole placement method with a rigid one-link manipulator. A position control simulation shows that the control algorithm can be used to control the position and residual oscillation of the flexible one-link manipulator effectively.