• 생물정신의학
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• 제12권2호
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• pp.173-180
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• 2005

Purpose:We investigated the effect of menopausal duration on cognitive function using adjunctive hormone replacement therapy(HRT) in postmenopausal women with depression. Method:Twelve postmenopausal women with depressive disorder were enrolled. Six patients having menopausal duration of less than 3 years was assigned to the short duration group and six patients of more than 3 years to the long duration group. Each patient was treated with conjugated equine estrogen(1.25mg) plus medroxyprogesterone(5mg) for 8 weeks. Cognitive performance was measured by the Verbal Memory Test, Visual Memory Test, Trail Making Test, Digit Symbol Test, and Attention Shift Test. The Beck Depression Inventory was used for evaluation of depressed mood. The reproductive hormone levels were also measured. Results:The long duration group showed the lower performance only in Trail Making Test B compared with the short duration group at baseline. After 8 weeks, the long duration group performed significantly better in the Trail Making Test B compared with the short duration group. The differences in change of depressive mood and gonadal hormone level between two groups were not significant. Conclusion:Menopausal duration before HRT may influence the effect of estrogen on cognition in some cognitive domains. This might be related with estrogen receptor hypersensitivity which induced by the longer estrogen deficiency.

• 대한불안의학회지
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• 제11권1호
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• pp.3-11
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• 2015

Objective : The aim of this study was to find associations between specific symptoms and suicidal behavior by using global severity on depression scales. Methods : Data were obtained from 1,183 patients of CRESCEND study. Factor analysis of the 17-item Hamilton Rating Scale for Depression (HAM-D) and the Beck Depression Inventory-II (BDI-II) was used to compare symptom clusters between the past suicide attempters and the non-suicide attempters, among the patients with depressive disorders. Results : Factor analyses of HAM-D and BDI-II extracted three factors. Suicide attempters had significantly higher scores on core factor of HAM-D, including depressed mood, feeling of guilt, suicide, work, and activities. The higher scores on all factors of BDI-II or scores correlated with a total of 7 suicide attempts and with known risk factors for suicidal behavior. Conclusion : These findings suggest that the suicide attempters complained of more cognitive, affective, somatic symptoms on BDI-II, but the core factor on HAM-D was the only differentiated factor between the two groups. Clinician-rated scales as well as self-reported questionnaires were valid in measuring suicidal attempts, and the clinical profile may help in guiding the studies of biological correlates and the treatments to reduce suicide risk.

• 감성과학
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• 제20권1호
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• pp.83-94
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• 2017

본 연구에서는 상품과 배경음악이 사람들의 충동적인 의사결정에 미치는 영향을 지연 할인의 쌍곡선 함수를 이용하여 알아보았다. 구체적으로 상품과 배경음악에 따라 유의미한 이원 상호 작용이 존재했다. 명품 조건에서는 모차르트의 피아노 콘체르토 5번 장조 음악을 들었을 때, 20번 단조 음악을 들었을 때보다 충동성이 유의미하게 높았다. 하지만 실용 상품에 노출된 참가자들에게선 음악의 종류에 따라 충동성의 차이는 유의미하지 않았다. 추가 연구를 통해 음악을 더 세분화하여 빠르기를 조절하여 그 영향을 알아보았으며 동시에 정서가 위와 같은 결과를 매개 했는지 알아보았다. 결과적으로 정서의 매개효과와 빠르기의 주효과 모두 유의미하지 않았지만, 빠르기와 장단조 조건 간의 유의미한 이원 상호작용이 나타났다. 구체적으로 알레그로(allegro) 빠르기에서는 장조음악일 때가 단조 조건일 때보다 충동성이 높은 경향성이 나타났으며 안단테(andante) 빠르기에서는 장조 음악을 들었을 때가 단조 음악을 들었을 때보다 유의미하게 충동성이 낮게 나타났다. 우울한 정서를 예측 변수로 하고 미래 시간 길이 지각을 매개 변인으로 하여 추가 연구를 진행한 결과, 시간 길이 지각은 우울한 정서가 충동성에 미치는 영향을 부분 매개함을 알 수 있었다.

• 정신신체의학
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• 제22권2호
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• pp.93-103
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• 2014

연구목적 본 연구의 목적은 조현병 외래 환자를 대상으로 야간식이증후군(night eating syndrome : NES)의 유병률과 이와 관련된 임상적 요인들에 대해 살펴보는 것이다. 방 법 정신건강의학과 외래를 방문한 201명의 조현병 환자들을 14 문항의 자기보고 형식인 야간식이증후군 설문지(Night Eating Questionnaire : NEQ)로 평가하였다. 인구학적, 임상적 특징과 체 질량 지수(BMI)을 조사하였고, 주관적인 기분과 수면, 폭식과 체중 관련 삶의 질에 대해서는 각각 Beck's Depression Inventory(BDI), Pittsburgh Sleep Quality Index(PSQI), Binge Eating Scale(BES)와 Korean version of Obesity-Related Quality of Life Scale(KOQoL)를 이용하여 평가하였다. 결 과 조현병 외래 환자에서 야간 식이 증후군의 유병률은 10.4%(201명 중 21명)이었다. NES 군과 non-NES 군간에 나이를 제외하면 인구사회학적 및 임상적 특성, BMI에서는 유의한 차이를 보이지 않았다. NES 군이 Non-NES 군에 비해 보다 우울했고, 수면과 폭식 양상, 체중 관련 삶의 질에 있어서 의미 있는 장애를 나타냈다. '아침 식욕부진'과 '지연된 아침식사'(NEQ에서 NES 핵심 항목 5개 중 2개)는 두 군간에 차이가 없었으나, '야간 섭식', '야간 식욕항진' 그리고 '기분/수면'은 NES 군에서 더 손상되어 있는 것으로 나타났다. 결 론 본 연구는 조현병 외래 환자를 대상으로 NES의 유병률과 관련 요인에 대해 기술한 최초의시도이다. 비록 NES와 비만과의 연관성은 밝히지 못했지만, 본 연구의 결과는 NES가 정신 건강에 부정적 영향을 준다는 사실을 보여주었다. 향후 이러한 결과를 뒷받침할 수 있는 추가 연구가 필요할 것이다.

• 정신신체의학
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• 제21권2호
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• pp.114-121
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• 2013

연구목적 타과 입원 중 정신건강의학과에 자문 의뢰된 초로기와 노년기 환자의 특징에는 어떠한 차이가 있는지 알아보기 위하여 연구를 실시하였다. 방 법 일 대학병원 정신건강의학과에 자문 의뢰된 타과 입원환자 중 50세부터 64세 범위의 초로기 환자(N=162)와 65세 이상의 노년기 환자(N=171)의 자문기록지를 비교분석하였다. 결 과 1) 정신건강의학과 자문의 주소는 초로기에 신체증상, 불안, 수면장애 순, 노년기에 인지저하, 의식혼탁, 우울한 기분 순으로 많았다. 2) 자문 결과에 의한 정신의학적 진단명은 초로기에 섬망, 기분장애, 물질사용장애순, 노년기에 섬망, 기분장애, 주요 신경인지장애 순으로 많았다. 3) 신체질환 치료제의 수는 초로기보다 노년기에 더 많았다. 결 론 정신건강의학과 자문의 특성은 초로기와 노년기 환자에서 차이가 있었으므로, 노인정신의학 자문 활동에 있어서 더욱 세분화된 노인 연령층별 접근이 필요하다고 제시된다.

• 정신신체의학
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• 제4권2호
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• pp.163-169
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• 1996

The authors examined for risk factors for suicide among psychiatric patients who had committed suicide through the analysis of demographic, clinical and psychological characteristics of the patients. The total number of suicides committed during social adjustment period was 9. Male and female ratio was 5:4 and the highest incidence occurred in the age group of 21-29 years. Of the 9 cases, schizophrenia accounted for two-third of the suicides. Among the committed suicides, 4 were in hospitalization and rest were postdischarge state. We found that 4 of 5(80%) suicides occurred in the first year after discharge, and that three fifth(60%) occurred within three months of discharge. In this result, most of suicides occurred immediately or soon after discharge and some during inpatient care. The major precipitating factors the patients showed before committing suicide were realistic and psychological problems. Consquently, they become dejected, experience feelings of hopelessness, go on to a depressed mood, and, in that case, have suicidal ideas that are eventually acted on. We believe that the ability to recognize risk factors for suicide and develop appropriate interventions is key to suicide prevention.

• 동의신경정신과학회지
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• 제19권3호
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• pp.231-244
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• 2008

Insomnia is one of the highest frequency neuropsychosis of neuropsychiatry patients and is primarily caused by major depressive disorder. This case study is about a remedy for a 33 year-old woman who has insomnia and intense depressed mood caused by the continuous family jar. Also, she had the feeling of squeezing her body, pouring cold water into her body, anorexia and feeling cold and hot turn and turn. I operated mindfullness with accupuncture, herb-medication and aroma theraphy. Especially, mindfullness and Gagamguibi-tang were effective for relaxation and the sound sleep in quality and quantity. According to this study, the traditional oriental medical remedy such as accupuncture, herb-medication is effective for the cure of insomnia and mindfullness fortifies the oriental medical remedy.

• 대한불안의학회지
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• 제9권2호
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• pp.93-100
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• 2013

Major depressive disorder causes significant dysfunction and disability. Many of depressed patients tend to have cormobid anxiety disorders, substance use disorders and personality disorders, and so on. In this study, we reviewed researches about the effects of comorbid anxiety disorder, substance use disorder on depressive symptoms, progress, treatment, etc. In addition, the latest knowledges related to treatment was reviewed. If the symptoms of anxiety disorder coexist, They leads to the deterioration of the course and has an adverse effect on treatment response. Comorbid substance use disorder, such as alcohol dependence, causes worsening of symptoms and progression, and a loss of therapeutic response. Therapeutic clinical guidelines and instructions to comorbid psychiatric disorders on major depressive disorder was not established clearly, but consensus-based or evidence-based studies will be necessary for treatment for comorbid psychiatric disorders on major depressive disorder.

• 성인간호학회지
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• 제17권2호
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• pp.239-247
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• 2005

Purpose: The purpose of this study is to examine the relationship among body image, depression and sexual function in Korean postmenopausal women. Methods: Subjects were 96 postmenopausal women who have lived in Korea. Data was collected using Semantic Differential scale, CES-D, and FSFI. Results: The level of body image was positive, depression was mild, and sexual function was moderate. There were no significant correlation between depression and sexual function. The subjects who had more positive body image experienced higher sexual function and less depressed mood. Conclusion: These findings showed the need for a knowledge development program for nurses regarding women's sexual function. Also, nurses must do counseling with sexual partner's and consider patients' body image when counseling those who complain of sexual dysfunction.

• 대한불안의학회지
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• 제4권2호
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• pp.127-134
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• 2008

Objective : This study examined whether major depressive disorder patients with anxiety traits displayed abnormal electroencephalographic (EEG) alpha asymmetries. Methods : Resting EEG was recorded in 11 outpatients with major depressive disorder (6 of whom had a high anxiety trait while 5 exhibited a low anxiety trait) and 6 controls. Results : In contrast to the controls, within the major depressive disorder patient group, comorbid anxiety disorder showed alpha asymmetry indicative of less activation over right than over left temporal sites. Patients diagnosed with major depressive disorder but no anxiety disorder showed a reduced temporal alpha asymmetry, supporting the potential importance of evaluating anxiety in studies of regional brain activation, in depressed patients. Conclusion : These findings suggest that anxiety is associated with brain hypoactivation, especially with right temporal hypoactivation.