• Journal of Korean Biological Nursing Science
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• 제22권3호
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• pp.192-203
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• 2020

Purpose: The purpose of this study was to identify the influencing factors of oral environment and self-care behavior on the oral health-related quality of life in the elderly with diabetes. Methods: The participants were 110 elderly patients with diabetes and follow-up care on their outpatient clinic in D and G city. Data were collected September-December 2018, using questionnaires of the Oral Health Impact Profile (OHIP-49) and Kim's Self-care Behavior, measuring with the tooth-pick (Premiers Dental), Halitosis Checker (HC-212M), and Moisture Checker for Mucus (MCM) for oral environments. The data were analyzed the by independent t-test, oneway ANOVA, Pearson's correlation, and stepwise multiple regression analysis using an IBM SPSS Statistics 25.0 Program. Results: There was positive correlation between oral health-related quality of life and self-care behavior (r= .61, p< .001), negative correlations among halitosis (r = -.34, p< .001), gingival index (r = -.31, p= .001) and plaque index (r = -.32, p= .001). Self-care behavior (β= .46, p< .001), subjective health status (good) (β= .23, p= .002), halitosis (β= -.16, p= .030), and plaque index (β= -.15, p= .041) explained 46.0% of the variance in the oral health-related quality of life. Conclusion: It is necessary to develop nursing care for elderly patients with diabetes that can enhance the self-care behavior and subjective health status, and lower halitosis and plaque index, the factors influencing the oral health-related quality of life in elderly patients with diabetes.

• 한국직업건강간호학회지
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• 제18권1호
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• pp.5-13
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• 2009

Purpose: The purpose of the study is to investigate health problems of migrant workers in Korea. Methods: The data were collected from the records of the medical history of 2,233 migrant workers who visited the community health clinic in Ansan city, Gyeonggi province from Jan. 2005 to Jan. 2007. The data were analyzed by SPSS. Results: Men accounted for 56.4% of the total who participated in the study. Most of them were Chinese, Russian, and Bangladesh people. The 590 people out of all the migrant workers were employed in manufacturing industries and they comprised the largest percentage. The most commonly complained health problems were musculoskeletal (31.7%), digestive (20.7%), respiratory (12.5%), dermatologic (6.5%), cardiovascular (5.5%) and dental disorder (5.2%). The 1,853 (36.0%) workers were assumed to have hypertensive disorder and 1310 (11.1%) workers, some diseases due to high cholesterol level. Conclusions: It is necessary to establish a public health care system to improve health and welfare of migrant workers. Furthermore, the communities need to draw their attention to this matter. And it is also necessary to make accurate research on their health and medical service.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권5호
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• pp.395-400
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• 2002

The purpose of this study was to investigate the relationship between oral cancer and such factors as smoking and drinking pattern, oral health status, dietary intake pattern, socio-economic status. Oral cancer patients and other disease patients who visited Yonsei University Dental Hospital from May to September in 2000 were selected as the study subjects. The numbers of cases and controls were 41, 108, respectively. Two groups were matched with age and sex for case control study. Oral examination and questionnaires survey was performed by the dentist. To assess the strength of associations between oral cancer and other variables, chisquare tests were performed. The results were as follows : 1. The durations of smoking and alcohol drinking were not related significantly with oral cancer. But the doses of smoking and alcohol intake increased the risk of oral cancer significantly(OR=2.52, 4.11, p<0.05). 2. Denture wearing, the number of missing teeth and spicy and salty food, coffee, tea and fresh fruit intake frequency did not significantly increase the risk of oral cancer. But low education level, residency in rural area increased risk of oral cancer significantly(p<0.01).

• Restorative Dentistry and Endodontics
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• 제20권2호
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• pp.843-855
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• 1995

Occupational Dentistry was introduced in Korea about 70 years ago. During the colonial period occupied by Japan till 1945, there were few documents about industrial dentistry, furthermore most cases of occupational diseases and accidents might have been concealed intentionally by the colonial government. After being an independent country, several dentists made efforts to set up 'Preventive Dentistry for Workers' performing specific oral health surveys, even though which were stopped by Korean War. In 1960s' and 1970s', some investigations of oral status were carried out intermittently for specific small groups;white-collar workers, mentally retarded person, buddhist monks and crews of ocean liners. At the same time there was important study in Korean history of occupational dentistry, which was 'a comparison of the oral hygiene conditions in the female workers of a spinning factory at intervals of 30 years.' In 1980s', young researchers began to give attention to erosion of the teeth due to sulphuric acid in the acid-related industry and dental caries due to sugar and flour in the sweets industry. After being democratic labor union movement activated in 1987, hidden and suppressed occupational diseases under the military dictatorship were exposed and flushed in the newspapers. It was shocking for all people that 15-year old boy had been dead due to mercury intoxication after 3-month employment in 1988. In 1990s', the activity for studying oral status of workers in their workplaces was launched and 'Occupational Accidents and Diseases in Oral and Maxillofacial Field' was published. And also The Korean Association of Occupationl Dentistry was established. Oral health examination of workers at the time of employment and of workers exposed to 5 special chemicals at the time of routine special health examination was adopted in 1992, and epocally oral health examination was also included in periodic routine examination of workers' health in 1995. So, occupational dentistry in Korea should cope with the changing needs of working environment and the altering scheme of health examination.

• 융합정보논문지
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• 제8권4호
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• pp.15-25
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• 2018

연구는 환경미화원의 구강건강행태를 파악하여 산업구강건강 증진을 위한 정책 방향의 기초를 마련하고자 한다. 광주광역시 일부 지역 환경미화원을 대상으로 자기기입식 설문 79부를 분석하였다. 연구결과 스케일링 경험 80%에 비해 구강보건교육 경험은 약 25%로 나타났다. 구강위생관리는 학력, 고용형태, 근무년수와 관계가 있었다. 치주상태는 고졸이상에서 '시린이'와 '잇몸부음' 증상이 높게 나타났고, 소득과 학력이 높을수록 치주상태가 '보통'이거나 '나쁨'으로 인식하였다. 따라서 다양한 노동자 중 환경미화원을 대상으로 분석한 것에 대하여 의의가 있으며, 환경미화원의 환경을 잘 고려하여 구강보건교육의 기회를 넓히고 적극적이고 융복합적인 프로그램을 개발하여 산업구강건강증진을 위한 다양한 노력과 대책이 필요하다.

• 융합정보논문지
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• 제9권3호
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• pp.90-97
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• 2019

본 연구는 중소 산업장 근로자의 구강건강관리행태 및 주관적 구강건강인식과 구강 내 산 생성도와의 관련성을 파악하기 위하여 중소 산업장 근로자 210명을 대상으로 구강 내 산 생성도 검사와 설문조사를 시행하였다. 그 결과 주관적 구강건강인식에 해당하는 주관적 구강건강상태가 구강 내 산 생성도에 유의미한 영향을 미치는 것으로 나타나, 주관적 구강건강상태가 좋지 않을수록 구강 내 산 생성도가 높았다. 이는 근로자의 구강건강증진을 위한 산업구강보건 프로그램 개발에 주관적 구강건강인식이 도움이 될 것으로 기대됨에 따라 근로자의 주관적 구강건강인식 개선을 위한 산업장 구강보건교육의 조직적 제도적 노력이 필요할 것으로 판단된다.

• 한국융합학회논문지
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• 제13권4호
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• pp.127-135
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• 2022

본 연구는 한국중년여성의 경제활동여부가 삶의 질과 구강건강에 미치는 융합적인 영향을 확인하기 위한 기초자료로 제공하고자 한다. 2019년 국민건강영양조사 자료를 사용하였고, 경제활동 여부가 구강건강관련 요인과 건강관련 삶의 질 (Korean Health-related Quality of Life Instrument with 8 Items; HINT-8)에 미치는 영향을 확인하기위해 복합표본 로지스틱 회귀분석과 선형회귀분석을 시행하였다. 그 결과, 인구학적 특성을 통제하고, 경제활동을 하는 경우 HINT-8의 하위항목 중 4개의 항목(기운, 일하기, 기억, 잠자기)에서 유의한 영향이 있었다. 구강건강 상태를 보정한 경우 HINT-8의 2개의 항목(일하기, 기억)에서만 유의한 영향이 있었다(p<.05). 따라서 한국 중년여성의 경제활동이 삶의 질에 긍정적인 영향을 미치지만 구강건강상태가 그 영향요인을 감소시킬 수 있다는 점에서 그 가치가 있다고 생각된다.

• 대한통합의학회지
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• 제11권3호
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• pp.159-169
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• 2023

Purpose : Though other Citrus spp. have reported their anti-inflammatory and antioxidative activities in previous studies, the biological activity of Kiyomi (Citrus unshiu × C. sinensis) has not been reported yet. Therefore, this study attempted to analyze the anti-inflammatory mechanisms of Kiyomi leaf ethanol extract (KLEE) in lipopolysaccharide (LPS) stimulated RAW 264.7 cells. Methods : The cytotoxic effect of KLEE in RAW 264.7 cells was determined by WST-1 assay. Bacterial endotoxin, the concentration of nitric oxide (NO) was analyzed by the Griess reaction. In addition, Western blot analysis was applied to measure the protein expression level of inducible NO synthase (iNOS). The phosphorylated status of the critical inflammatory transcription factor, nuclear factor (NF)-𝜅B, and its upstream signaling molecules, phosphoinositide 3-kinase (PI3K)/Akt as well as mitogen-activated protein kinases (MAPKs), were also measured by Western blot analysis. Results : KLEE was not cytotoxic up to a concentration of 200 ㎍/㎖, and protein expression levels of iNOS and cyclooxygenase (COX)-2, enzymes that counteract NO and prostaglandin (PG) E2 production, were inhibited by KLEE treatment. The phosphorylated status of PI3K/Akt as well as MAPKs including extracellular regulated kinase (ERK), c-jun NH2kinase (JNK), and p38, were significantly attenuated by KLEE treatment in LPS stimulated RAW 264.7 cells. Moreover, one of phase II enzymes, heme oxygenase (HO)-1 which has known for its anti-inflammatory capacity, was strongly induced by KLEE treatment. Conclusion : Consequently, KLEE treatment significantly attenuated the production of NO as well as the expression levels of iNOS and COX-2 in LPS-stimulated RAW 264.7 cells. The inflammatory transcription factor, NF-𝜅B, as well as its upstream signaling molecules, PI3K/Akt and MAPKs, were also diminished by KLEE treatment with statistical significance in LPS-stimulated RAW 264.7 cells. These results suggest that KLEE might be a promising candidate for the attenuation of inflammatory disorders.

• 대한통합의학회지
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• 제11권2호
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• pp.119-128
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• 2023

Purpose : The fruit of Actinidia polygama has been used in oriental medicine for the treatment of gout, rheumatoid arthritis, and inflammation. Though A. polygama exhibited anti-inflammatory activity in RAW 264.7 cells and carrageenan-induced rat paw edema, the exact mechanism for anti-inflammation was not evaluated yet. In this study, the anti-inflammatory mechanisms of A. polygama ethanol extract (APEE) in lipopolysaccharide (LPS) stimulated RAW 264.7 cells. Methods : WST-1 assay was applied to analyze the cytotoxic effect of APEE in RAW 264.7 cells. The productions of nitric oxide (NO) and prostaglandin (PG) E₂ were analyzed by the Griess reaction and enzyme immunoassay (EIA) assay, respectively. In addition, protein expressions for inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 were measured by Western blot analysis. The activated status of an inflammatory transcription factor, NF-κ B, and its upstream signaling molecules, mitogen-activated protein kinases (MAPKs), was also evaluated by Western blot analysis. Results : As a result, APEE treatment did not exhibit any cytotoxicity until the concentration of 200 ㎍/㎖. APEE treatment significantly inhibited NO and PGE₂ productions as well as their enzymes, iNOS and COX-2 in a dose-dependent manner. The inflammatory transcription factor, NF-κ B, was also attenuated by APEE treatment. In addition, the phosphorylated status of MAPKs such as extracellular regulated kinase (ERK), c-jun NH2 kinase (JNK), and p38, were significantly diminished by APEE treatment in LPS stimulated RAW 264.7 cells. Conclusion : Consequently, APEE treatment significantly attenuated the production of inflammatory mediators and their enzyme expressions in LPS-stimulated RAW 264.7 cells. The inflammatory transcription factor, NF-κ B, and upstream signaling molecules, MAPKs, were also significantly attenuated by APEE treatment in LPS-activated RAW 264.7 cells. These results indicate that APEE might be a candidate to be utilized as a promising candidate for the treatment of inflammatory disorders.

• 보건의료생명과학 논문지
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• 제10권1호
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• pp.157-162
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• 2022

흡연은 음주와 더불어 치주질환을 유발하는 원인 인자로 알려져 있으나, 흡연여부에 따른 구취와 구강 내 분포하는 미생물을 조사한 연구는 현재 매우 미비한 상태이다. 본 연구에서는 대학생을 대상으로 흡연자 30명, 비흡연자 30명을 선정하였다. 구강질환과 관련한 Streptococcus mutans 와 Prevotella intermedia 균들은 흡연자에서 30%, 비흡연자에서 7%로 흡연자에서 더 많이 검출되었으며, 1일 칫솔질 3회 이하에서 20%로 검출되어 통계적으로 유의하였다. 수분섭취량과 구취, 구강 미생물에서 차이를 확인한 결과 구강 미생물 중 P. intermedia는 통계적으로 유의한 차이가 있는 것으로 분석되었다(p<0.05). P. intermedia는 비흡연자보다 흡연자에서 세균이 더 검출되어 유의하였다(p<0.05). 지속적인 흡연은 구강을 직접적으로 자극하여 비흡연자에 비해 구강질환을 유발할 수 있는 세균이 우세하게 나타날 수 있으므로 흡연은 균주와 함께 구강 내 환경을 악화시켜 구강질환을 유발하는 원인임을 상기시켜 경각심을 주고, 더 나아가 학생들의 금연에도 긍정적 효과를 끼칠 것으로 기대한다.