• IMMUNE NETWORK
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• 제15권4호
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• pp.206-211
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• 2015

Pulmonary edema is a major cause of mortality due to acute lung injury (ALI). The involvement of protein kinase C-${\delta}$ (PKC-${\delta}$) in ALI has been a controversial topic. Here we investigated PKC-${\delta}$ function in ALI using PKC-${\delta}$ knockout (KO) mice and PKC inhibitors. Our results indicated that although the ability to produce proinflammatory mediators in response to LPS injury in PKC-${\delta}$ KO mice was similar to that of control mice, they showed enhanced recruitment of neutrophils to the lung and more severe pulmonary edema. PKC-${\delta}$ inhibition promoted barrier dysfunction in an endothelial cell layer in vitro, and administration of a PKC-${\delta}$-specific inhibitor significantly increased steady state vascular permeability. A neutrophil transmigration assay indicated that the PKC-${\delta}$ inhibition increased neutrophil transmigration through an endothelial monolayer. This suggests that PKC-${\delta}$ inhibition induces structural changes in endothelial cells, allowing extravasation of proteins and neutrophils.

• Molecules and Cells
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• 제27권1호
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• pp.89-97
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• 2009

We investigate the molecular and cellular etiologies that underlie the deletion of the six amino acid residues (${\Delta}F323-Y328$; ${\Delta}FY$) in human torsin A (HtorA). The most common and severe mutation involved with early-onset torsion dystonia is a glutamic acid deletion (${\Delta}E$ 302/303; ${\Delta}E$) in HtorA which induces protein aggregates in neurons and cells. Even though ${\Delta}FY$ HtorA forms no protein clusters, flies expressing ${\Delta}FY$ HtorA in neurons or muscles manifested a similar but delayed onset of adult locomotor disability compared with flies expressing ${\Delta}E$ in HtorA. In addition, flies expressing ${\Delta}FY$ HtorA had fewer aberrant ultrastructures at synapses compared with flies expressing ${\Delta}E$ HtorA. Taken together, the ${\Delta}FY$ mutation in HtorA may be responsible for behavioral and anatomical aberrations in Drosophila.

• 한국해양학회지:바다
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• 제5권4호
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• pp.357-362
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• 2000

황해 남부해역에서 199년 8월에 채집된 시료로부터 산소동위원소비(${\delta}^{18}$O)와 수소동위원소비(${\delta}$D)를 측정하였다. 표층시료의 경우 염분과 ${\delta}^{18}$O 그리고 염분과 ${\delta}$D는 앙의 상관관계를 보이며, ${\delta}^{18}$O와 ${\delta}$D 또한 매우 좋은 양의 상관관계를 가진다. 이들 자료는 연구지역의 해수가 장강수와 변형된 쿠로시오수의 혼합물이며 , 산소와 수소 동위원소가 연구지역에서 수괴의 성질과 행동을 연구하는데 유용한 추적자로 사용될 수 있다는 것을 의미한다. 또한 염분과 수온만으로는 구별이 어려운 수괴를 구분하고 특성을 파악하는데도 안정등위원소가 좋은 추적자로 사용될 수도 있음을 보여 주었다.

• 대한수학회보
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• 제51권3호
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• pp.659-666
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• 2014

Let $\mathcal{A}$ be the class of analytic functions f in the open unit disk $\mathbb{U}$={z : ${\mid}z{\mid}$ < 1} with the normalization conditions $f(0)=f^{\prime}(0)-1=0$. If $f(z)=z+\sum_{n=2}^{\infty}a_nz^n$ and ${\delta}$ > 0 are given, then the $T_{\delta}$-neighborhood of the function f is defined as $$TN_{\delta}(f)\{g(z)=z+\sum_{n=2}^{\infty}b_nz^n{\in}\mathcal{A}:\sum_{n=2}^{\infty}T_n{\mid}a_n-b_n{\mid}{\leq}{\delta}\}$$, where $T=\{T_n\}_{n=2}^{\infty}$ is a sequence of positive numbers. In the present paper we investigate some problems concerning $T_{\delta}$-neighborhoods of function in various classes of analytic functions with $T=\{2^{-n}/n^2\}_{n=2}^{\infty}$. We also find bounds for $^{\delta}^*_T(A,B)$ defined by $$^{\delta}^*_T(A,B)=jnf\{{\delta}&gt;0:B{\subset}TN_{\delta}(f)\;for\;all\;f{\in}A\}$$ where A, B are given subsets of $\mathcal{A}$.

• 한국세라믹학회지
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• 제31권12호
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• pp.1491-1500
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• 1994

Nonstoichiometry($\delta$) and the phase stability region of a ferrite spinel (Mg0.29Fe0.71)3-$\delta$O4 have been investigated by a coulometric titration method as a function of temperature(T) and oxygen partial pressure(Po2). It has been found that the spinel is thermodynamically stable in the ranges -8.0$\leq$log(PO2/atm)$\leq$-2.4, -7.0$\leq$log(PO2/atm)$\leq$-1.7 respectvely at 100$0^{\circ}C$. The nonstoichiometry extends over the ranges of -0.004$\leq$$\delta$$\leq$0.007, -0.008$\leq$$\delta$$\leq$0.006, -0.033$\leq$$\delta$$\leq$0.004 at 100$0^{\circ}C$, 120$0^{\circ}C$, respectvely. The observed PO2-dependence of $\delta$ suggests that the majority ionic defects are cation interstitials in the low PO2 region and cation vacancies in the high PO2 region.

• 대한기계학회논문집
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• 제9권1호
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• pp.1-9
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• 1985

본 연구에서는 이러한 점에도 역점을 두어서 초기 피로균열의 발생.거동을 관 찰하기 쉬운 연강을 선택하여 편진인장반복하중을 작용시켜, 연강 평골재의 표면상에 발생.성장하는 미소표면균열의 거동을 전자현미경과 광학현미경을 병용하여 표면과 파 단면을 입체적으로 조사하여, 피로균열의 초기발생상태를 조사하고, 그 성장율을 조사 하여 파괴역학적으로 해석하여 그 특성을 조사한다.

• 전자공학회논문지CI
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• 제39권4호
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• pp.19-27
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• 2002

역전파 알고리즘의 성능 개선을 위해서 학습율을 자동 조정하는 방식을 제안하였다. 제안한 방식은 각각의 연결강도의 학습율을 퍼지 논리 시스템을 이용하여 자동 조정하는 방식으로 각각의 연결강도에 대해서 ${\Delta}$와 $\bar{{\Delta}}$를 구하여 퍼지 논리 시스템의 입력으로 사용하고, 학습율을 출력으로 사용하였다. 제안한 방식을 N-패리티 문제, 함수 근사, 숫자 패턴 분류에 대한 시뮬레이션 결과 일반적인 역전파 알고리즘, 모멘텀 방식, Jacobs의 delta-bar-delta 방식보다 성능이 개선됨을 확인하였다.

• 대한수학회보
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• 제31권2호
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• pp.193-200
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• 1994

Let x : $M^{n}$ .rarw. $E^{m}$ be an isometric immersion of a manifold $M^{n}$ into the Euclidean space $E^{m}$ and .DELTA. the Laplacian of $M^{n}$ defined by -div.omicron.grad. The family of such immersions satisfying the condition .DELTA.x = .lambda.x, .lambda..mem.R, is characterized by a well known result ot Takahashi (8]): they are either minimal in $E^{m}$ or minimal in some Euclidean hypersphere. As a generalization of Takahashi's result, many authors ([3,6,7]) studied the hypersurfaces $M^{n}$ in $E^{n+1}$ satisfying .DELTA.x = Ax + b, where A is a square matrix and b is a vector in $E^{n+1}$, and they proved independently that such hypersurfaces are either minimal in $E^{n+1}$ or hyperspheres or spherical cylinders. Since .DELTA.x = -nH, the submanifolds mentioned above satisfy .DELTA.H = .lambda.H or .DELTA.H = AH, where H is the mean curvature vector field of M. And the family of hypersurfaces satisfying .DELTA.H = .lambda.H was explored for some cases in [4]. In this paper, we classify space curves x : R .rarw. $E^{3}$ satisfying .DELTA.x = Ax + b or .DELTA.H = AH, and find conditions for such curves to be equivalent.alent.alent.

• 한국세라믹학회지
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• 제36권7호
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• pp.679-684
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• 1999

Specimens of SrZr0.95Ga0.05O3-$\delta$, SrZr0.95Y0.05O3-$\delta$, BaZr0.95Ga0.05O3-$\delta$ and BaZr0.95Y0.05O3-$\delta$ were fabricated by a solid-state reaction method and subsequent sintering at 150$0^{\circ}C$ to 1$600^{\circ}C$ The microstructures and electrical characteristics of the specimens were studied. Only BaZr0.95Ga0.05O3-$\delta$ showed dense microstructure and had typical impedance spectra at various temperature. Its electrical conductivity by impedance analysis was 2.7$\times$10-3$\Omega$-1.cm-1 at 90$0^{\circ}C$ in air. The BaZr0.95Ga0.05O3-$\delta$ exhibited lower grain rsistance in wet atmosphere than in dry atmosphere and the reduction of resistance is due to the proton conduction.

• 한국안전학회지
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• 제11권2호
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• pp.16-24
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• 1996

In this study we simulate the fatigue test of a compact tension specimen and obtain the displacements, stresses and strains by using the finite element method. And we examine the path independency of $\Delta$J integral values and compare it with $\Delta$J integral values calculated from load-load line displacement curve. From the results of this study, we can find that $\Delta$J integral show the path Independency for saturated materials. We can also find that the path independency of $\Delta$J Is not satisfied when different material Is assumed near the crack tip, but the difference in $\Delta$J is small. And $\Delta$J integral values calculated from load-load line displacement is very analogous with those from integration path but always have lower values than those from integration paths. In the case of crack closing, we found that $\Delta$J integral values from load-load line displacement should be calculated with the load Increment values based on the crack opening point. The unsaturated material is also simulated and its $\Delta$J shows different values according to the path, but the difference is small.