• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1187-1192
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• 2014

Background: To correlate breast cancer subtypes with prognostic factors, microvessel density (MVD), vascular endothelial growth factor (VEGF) expression and clinical features. Materials and Methods: One hundred cases of primary breast carcinoma were classified using biomarkers on tissue microarray as: luminal A [estrogen receptor (ER)+, HER2-, $Ki-67{\leq}14%$], luminal B [ER+, HER2+ or ER+, HER2-, Ki-67>14%], HER2, triple negative basal-like (TNB) [any basal cytokeratins (CKs, 5, 14, 17) and/or endothelial growth factor receptor (EGFR) expression], and TN without such markers [TNN, null], and assessed for p53, vimentin, VEGF and CD31 immunoperoxidase. Results: Of the 100 cases (mean age, 51 years; mean tumor size, 3.2cm; 56% with nodal metastasis; 89 invasive ductal carcinomas, not otherwise specified, 4 invasive lobular carcinomas, 3 metaplastic carcinomas, and 4 other types) there were 39 luminal A, 18 luminal B, 18 HER2, 15 TNB and 10 TNN. The positivities of basal-like markers in the basal-like subtype were 78.3% for CK5, 40% for CK14, 20% for CK17, 46.7% for EGFR. There was no significant difference in age distribution, tumor size, degree of tubular formation, pleomorphism, lymphovascular invasion, nodal metastasis, MVD, VEGF expression and survival among subgroups. TNs demonstrated significantly higher tumor grade, mitotic count, Ki-67 index, p53 and vimentin and decreased overall survival compared with nonTN. Conclusions: The distribution of breast cancer subtypes in this study was similar to other Asian countries with a high prevalence of TN. The high grade character of TN was confirmed and CK5 expression was found to be common in our basal-like subtype. No significant elevation of MVD or VEGF expression was apparent.

• The Journal of the Acoustical Society of Korea
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• v.19 no.6
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• pp.53-61
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• 2000

In the speech recognition under the noisy environments, reducing the mismatch introduced between training and testing environments is an important issue. Spectral subtraction is widely used technique because of its simplicity and relatively good performance in noisy environments. In this paper, we introduce histogram method as a reliable noise estimation approach for spectral subtraction. This method has advantages over the conventional noise estimation methods in that it does not need to detect non-speech intervals and it can estimate the noise spectra even in time-varying noise environments. Even though spectral subtraction is performed using a reliable average noise spectrum by the histogram method, considerable amount of residual noise remains due to the variations of instantaneous noise spectrum about mean. To overcome this limitation, we propose a new over-estimation technique based on distribution characteristics of histogram used for noise estimation. Since the proposed technique decides the degree of over-estimation adaptively according to the measured noise distribution, it has advantages to be few the influence of the SNR variation on the noise levels. According to speaker-independent isolated word recognition experiments in car noise environment under various SNR conditions, the proposed histogram-based over-estimation technique outperforms the conventional over-estimation technique.

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.2
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• pp.209-220
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• 2001

Objectives : The aim of this study was to investigate the attitude toward the oriental hospital among 100 pediatric outpatients. Methods : A questionnaire about the general characteristics of patients. the reason of choice or alteration was implemented. Results : 1. In distribution of sex & age, 60% was men and 40% women was between 2 and 6 years old. 2. In determinant factor for using Oriental medicine, 43.8% was tolerance increase of the western medicine and 33.0% was recommened by others. 3. In distribution of disease & therapeutic method, 62.5% was respiratory disease and 11.7% gastrointestinal disease, 64.3% was treated with oriental after Western medical therapy and 20.9% only Oriental medical care. 4. The changing causes for using Oriental after Western medicine, 35.9% was ineffective affect and 26.5% side effect. 5. The preference for using Oriental medicine, 41.6% was respiratory disease and 21.0% gastrointestinal disease. 6. The peculiarity of Oriental medicine compared with western medicine, 36% was effectiveness on the cronic disease and 14% for fundamental remedy. 7. The prodominance disease in Western medicine compared with Oriental medicine, 28% was operation, 18% common cold and 15% inflammatory disease 8. The questions about Oriental medicine, 22% was medical material's sanitation and place of origin, 18% harmness or not administered during long time. 9. The controversial point of Oriental medicine, 33.5% was expensive price and 27.7% difficulty of taking medicine. 10. In satisfaction degree of Oriental medicine, 69% was satisfied and 19% was very satisfied. Conclusions : Considering the above results, we have concluded that proper recognition about Oriental Pediatric medicine will be needed among patients.

• Journal of Distribution Research
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• v.11 no.4
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• pp.97-124
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• 2006

This study investigates the relationship between the relationship marketing factors, relationship quality and store loyalty in retail specialty stores. The customization of a retail specialty store was found to be having a larger effect on relationship quality than other factors such as expertise, bonding and communication and the moderating effects of customer characteristic was found be having a larger effect on relationship quality all factors except to communication. The result of this study has some practical implications. First of all, the customization strategy for individual customers is needed because customers trusted employees who provide a customized service more. Second, the employees' expertise is important to obtain the trust of customers. Third, the findings of the study showed that the communication with employees did not affect the trust. Rather, customers more often want price discounts, useful information, other benefits related to transactions. The communication is also necessary to bond a strong relationship with customers, as well as to respond customer's requests immediately Fourth, the marketing managers of the store have to effectively manage the customer relationship with the special consideration to the customer's gender, transaction experience, and variety seeking disposition.

• The Journal of Industrial Distribution & Business
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• v.9 no.5
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• pp.47-62
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• 2018

Purpose - Based on preceding studies, this thesis focuses on the finding of the definition and category of mobile tourism application and deriving out its characteristics. And after looking for how they make influences on continuous intention to use, we make empirical study with TAM model. Research design, data, and methodology - There are many Chinese tourist who visit Korea with user's constant intention to use of tourism application. This study is to find out the definition and category of mobile tourism application through research of preceding study and to fomulate the research model and hypothesis that how tourism application attributes (convenience, interaction, accessibility, local basis, security) affect constant intention to use of mobile tourism application. In order to verify a hypothesis, we conducted a survey for Chinese users of tourism application. In empirical study, we analyzed a structure model for frequency analysis, reliability analysis, exploratory factor analysis, validity analysis through IBM SPSS Statistics 21.0 and IBM SPSS AMOS 21.0 Results - Among tourism applications, convenience, interaction, accessibility and local basis have positive effects on both perceived usefulness and perceived easiness respectively. But security does not. Also perceived easiness has a positive effect on perceived usefulness. Finally, perceived usefulness and perceived easiness have positive effect on constant intent to use. Conclusions - Tourism application enterprises should put emphasis on design such as menu or function in order to simplify the operation of new services for new customers. Therefore, comfortable user interface and development of useful function can improve tourism application. Consequently, it leads to the promotion of tourism application. Also, when users perceive tourism application as a useful media which is easy, comfortable and useful content, the degree of constant intention to use becomes increased. It is important to provide plentiful and useful contents for customers and to develop user interface such as easy operation because these factors have positive effects on constant demand and use of tourism application.

• Journal of Distribution Science
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• v.18 no.2
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• pp.99-108
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• 2020

Purpose: This paper investigated the relationship between market competition and firm valuation error. Furthermore, Additional analyses were made according to the quality of financial reports and the listed market. Through the process we confirm to the impact of competition on the capital market. The purpose of this study is to analyze the impact of competition on valuation errors. The preceding studies did not provide a consistent results of the effects of competing functions on the capital market. One view is that the competition could mitigate the information asymmetry, and the other is that monopolistic lessens the manager's involvement in financial reporting. This study is intended to expand the prior study by analyzing the impact of competition on the capital market and on the valuation of investors. Research design, data, and methodology: The analysis was conducted on 12,031 samples over 11 years from 2008 to 2018 using data from market in Korea. Here the valuation error was measured by the research methodology of Rhodes-Kropf, Robinson and Viswanathan (2005), and competition measured by Herfindahl-Hirschman Index multiplied by (-1), and Concentration Ratio by (-1). Results: We confirm that the positive relationship between competition and the valuation error. In addition, we also found that the positive relation between competition and valuation error was in cases of low discretionary accruals and the KOSDAQ market. This means that the net function of competition does not mitigate valuation errors. Conclusions. This study has the following contributions when compared to prior research. First, the relevance between the level of competition and the valuation of the entity was confirmed. The study by Haw, Hu and Lee (2015) suggested that monopolistic industry of analysts' forecast is more accurate due to lower the variability in earnings. This study magnified it to confirm that monopolistic lessen information uncertainty in valuation. Second, the study on valuation errors was expanded. While the study on the effect of valuation errors on the capital market is generally relatively active, it is different that competition degree has analyzed the effect on valuation errors amid the lack of research on the effect on valuation errors.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.8 no.4
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• pp.305-312
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• 2014

In this study, in order to quantitatively confirm walking rehabilitation degree, we analyzed EMG pattern simulated abnormal gait and normal gait by applying a curve fitting. We calculated the suitable high-order function for EMG signal, and classified them into 5 groups by using cluster analysis. Depending on the distance from normal pattern group, we listed the pattern group and then the distribution of each variables were confirmed. The amplitude-decreased pattern was the most similar to the normal pattern, but the reversed pattern showed the lowest similarity. Due to the smaller overlapping range, the distribution of the groups were possible to classify using the value of variable. The standard deviation of each term coefficient was compared to indicate the quantitative rehabilitation extent, and the higher value was confirmed as the pattern is close to the normal pattern. Consequently, the representation of quantitative rehabilitation extent is expected to contribute to the more effective rehabilitation method study.

• Polymer(Korea)
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• v.25 no.6
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• pp.765-773
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• 2001

In In order to remove harmful trace elements such as $Co^{2+}$, $Ni^{2+}$ , $Cr_2O_7\;^{2-}$ from water, we synthesized AN-co-(MMA/IA) according to various mole ratio of monomers and spun by wet-spinning. And multi-functional PAN ion exchangers were prepared by hydrolysis. We observed structure, degree of functionalization, ion exchange capacity, distribution coefficient and mechanical properties for ion exchanger. Anion exchange capacity decreased in 4.5 ~ 4.2 meq/g with increasing of IA content and cation exchange capacity increased in 1.8 ~ 2.2 meq/g. Tensile strength of the ion exchanger increased up to 0.008 mol% IA content and appeared maximum value by 216$kg/cm^2$Distribution coefficient for AN-co-(MMA/IA) ion exchanger appeared maximum value for Co(II), Ni(II) in pH 5-6 range and for Cr(III) in pH 3-4 range. And the adsorption capacity was in the order of Cr(III) > Co(II) > Ni(II) for multicomponent in continuous process.

• Food Science and Preservation
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• v.10 no.1
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• pp.70-74
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• 2003

The distribution of mesophilic and thermophilic bacteria in milled rice was not different according to growing land and variety of rice. However, The number of these bacteria were abundant in milled rice of lower milling degree or longer storage period. The growth of thermophilic bacteria in cooked rice of electric rice cooker was rapidly increased during storage of lower temperature below 75 $^{\circ}C$. Thermophilic bacteria were not appeared just after cooking. After cooked rice was stored far 18∼24 hon thermophilic bacterial growth was rapidly increased by changing spore to vegetative cell. The positive relation between cell number of thermophilic bacteria and occurrence of off-odor was slightly observed. The number of thermophilic bacteria in upper cooked rice of oven and was higher than those in inner and lower cooked rice. Major volatile compound of milled rice cooked and stored in electric rice cooker was hexanal oriented from rice. After long storage, it was confirmed that furan was major volatile compound as off-odor.

• Tunnel and Underground Space
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• v.12 no.3
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• pp.220-228
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• 2002

Thermal flow through jointed rock mass was analyzed by numerical methods. The effect of a single set of joints on the heat conduction was analyzed by one-dimensional model and compared with the analytical solution. When a joint is completely dry, the joint behaves as a thermal break inducing jumps in temperature distribution even at steady state. Therefore when joints are completely dry, individual joint has to be taken into consideration to get a good result. When joints are partially or fully saturated, the thermal conductivity of the joints increases drastically and the jumps in temperature distribution become less severe. Therefore the effect of joint in heat conduction can be well absorbed by continuum anisotropic model whose thermal properties represent overall thermal properties of the intact part and the discontinuities. Since the effect of joints becomes less important as the degree of the saturation increases, the overall thermal response of the rock mass also becomes close to isotropic. Therefore it can be concluded that a great effort has to be made to obtain a precise in-situ thermal properties in order to get a good prediction of the thermal response of a jointed rock mass.