• Title/Summary/Keyword: deficient

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Dielectric Properties of Cation-deficient Perovskite Ceramics and Oscillator Application (Cation-deficient 페로브스카이트 세라믹스의 유전 특성과 발진기 응용)

  • Kim, Jae-Sik;Choi, Eui-Sun;Ryu, Ki-Won;Lee, Young-Hie
    • Proceedings of the KIEE Conference
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    • 2006.10a
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    • pp.18-19
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    • 2006
  • In this study, dielectric properties of the ${Mg_5}{B_4}{O_{15}}$ (B=Ta, Nb) cation-deficient perovskite ceramics and its oscillator application are investigated. The cation-deficient perovskite ceramics are prepared through the solid-state route. According to the XRD pattern, ${Mg_4}{Ta_2}{O_9}$ and $Mg{Ta_2}{O_6}$ phase existed in calcined and sintered ${Mg_5}{Ta_4}{O_15}$ powder. Also ${Mg_5}{Ta_4}{O_{15}}$ phase added with increasing sintering temperature. In the case of calcined and sintered ${Mg_5}{Nb_4}{O_{15}}$ powder, single phase of ${Mg_5}{Nb_4}{O_{15}}$ is appeared. In the case of the ${Mg_5}{Ta_4}{O_{15}}$ and ${Mg_5}{Nb_4}{O_{15}}$ ceramics sintered at $1450^{\circ}C$ for 5h, the dielectric constant, quality factor, and temperature coefficient of the resonant frequency (TCRF) were 8.2, 259,473 GHz, $-10.91ppm/^{\circ}C$ and 14, 37,350 GHz, $-52.3\;ppm/^{\circ}C$, respectively. Simulated DR with ${Mg_5}{Ta_4}{O_{15}}$ ceramics had the operating frequency of 10.99 GHz and S(2,1) of -29.795 dB. Size of manufactured oscillator was $56{\times}48{\times}34\;mm^3 and operated at 11.93 GHz. Power output and second harmonic of oscillator were +13.61 dBm and -23.81 dBc at 23.85 GHz, respectively.

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Study on the Chapter of Heart Deficient Prescrition in Mai-zheng-fang-you-ge-bian(脈證方藥合編) ("증맥방약합편(證脈方藥合編).활투침선(活套針線).허로문(虛勞門)"에 나타난 심허(心虛) 처방에 대한 연구)

  • Choi, Geun-Jo;Kang, Jung-Soo
    • Journal of Haehwa Medicine
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    • v.16 no.2
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    • pp.109-119
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    • 2007
  • Xu-lao(虛勞) is deficient disease which is weak body and spirit. It occurs many symptoms, for example lack of appetite, dizziness, involuntary emission of semen, wet dream, back and chest pain, night sweat, cough and so on. In oriental medicine, xu-lao(虛勞) is well-known disease and can be treated easily. In general, xu-lao (虛勞) patiences like to be treated by oriental medical doctors. In spite of improving food, house and clothes, xu-lao(虛勞) is on the increase by fatty foods and stress. In most of these cases, the cooperations of heart and kidney are hurted. On Fang-you-ge-bian(脈證方藥合編) which is the famous prescription book in Korea, gu-an-xin-shen-wan(古庵心腎丸) and Jiu-yuan-xin-shen-wan(究原心腎丸) are used well and have good effects in these cases. Gu-an-xin-shen-wan(古庵心腎丸) can treat white hair, palpitation, involuntary emission of semen, amblyopia, buzzing in the ears, backache and so on. Jiu-yuan-xin-shen-wan(究原心腎丸) can treat lack of appetite, dizziness, involuntary emission of semen, wet dream, back and chest pain, diseased sweat, cough, coldness of hands and feet, and so on. The symptoms of Gu-an-xin-shen-wan(古庵心腎丸) are similar with those of Jiu-yuan-xin-shen-wan(究原心腎丸). But, it is very important that Gu-an-xin-shen-wan(古庵心腎丸) can be used in cases of hot deficient disease but Jiu-yuan-xin-shen-wan(究原心腎丸) can be used in cases of cold deficient disease.

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Manufacturing of Calcium Binding Peptide using Sericin Hydrolysate and Its Bioavailability in Calcium Deficient Rat (실크 세리신 단백질 가수분해물을 이용한 유기 칼슘제의 제조 및 칼슘 결핍 쥐에서의 생체 이용률)

  • Cho, Hye-Jin;Lee, Hyun-Sun;Jung, Eun-Young;Suh, Hyung-Joo
    • Journal of the East Asian Society of Dietary Life
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    • v.20 no.5
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    • pp.680-686
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    • 2010
  • Silk sericin protein was hydrolyzed by seven proteolytic enzymes in order to examine the effectiveness of the hydrolysates in binding calcium. The amino acid nitrogen content of hydrolysates from Flavourzyme was higher than that for other enzymes, and its calcium binding capacity showed a dose-dependent increase. We examined the effects of calcium binding peptide from sericin hydolysates on the bioavailability of Ca-deficient rats. Three-week-old male rats were fed an Ca-deficient diet for three weeks. Rats were divided into four groups (DD: non-treated group on calcium deficient diet; DD+MC: milk-calcium treated group; DD+OC: organic calcium made using sericin hydolysates; and DD+IC: inorganic calcium ($CaCl_2$). After oral administration of calcium supplements for one week, the calcium content of the serum and liver were significantly higher in DD+OC ($101.7{\mu}g$/mL and $49.3{\mu}g$/mL) and DD+MC ($83.6{\mu}g$/mL and $42.8{\mu}g$/mL) than DD ($86.3{\mu}g$/mL and $43.4{\mu}g$/mL). The alkaline phosphatase (ALP) content in the treated groups was significantly lower than DD, but no significant difference among groups was shown. Aspartate aminotransferase (AST) levels did not show any significant difference between groups. Alanine aminotransferase (ALT) levels were significantly reduced compared to the DD group. In conclusion, binding calcium to peptides from sericin hydrolysates seems to improve its bioavailability, and to hasten the cure of calcium deficiency in experimental rats.

Metabolic Syndrome Risk according to Fruit and Vegetable Intake in Middle-aged Men - Using the Korea National Health and Nutrition Examination Survey (KNHANES) 2013~2015 - (중년 남성에서 과일·채소 섭취량에 따른 대사증후군 위험도 비교 - 제6기(2013~2015년) 국민건강영양조사 자료 이용 -)

  • Her, Eun-Sil
    • The Korean Journal of Food And Nutrition
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    • v.30 no.5
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    • pp.1048-1057
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    • 2017
  • The purpose of this study was to compare nutrient intake, health-related factors, and risk factors for metabolic syndrome and to investigate the prevalence odds ratio according to fruit and vegetable intake among middle-aged Korean men. Subjects included 1,677 men aged 40 - 64 years. The average intake of fruits and vegetables was $578.48{\pm}5.90g/day$. Forty-nine percent of the subjects were categorized into the deficient group based on the intake of fruits and vegetables, and the other subjects were categorized into the adequate group. There was a significant difference in the nutrient density per 1,000 kcal of energy, minerals, vitamins, and dietary fiber between the fruit and vegetable intake groups (p<0.001). In terms of health-related factors, only the current smoking rate in the deficient group (57.9%) was higher than that in the adequate group (45.4%) (p<0.001). There was no significant difference in the risk factors for metabolic syndrome between the fruit and vegetable intake groups. Proportion of serum triglycerides (42.6%) was the highest at a rate that exceeded the criteria for risk factors for metabolic syndrome, but systolic blood pressure (21.7%) showed a very low rate. The fasting blood glucose, serum triglycerides, and diastolic blood pressure were significantly higher in the deficient group than in the adequate group (p<0.05). Prevalence of metabolic syndrome was 31.2%. OR for prevalence of metabolic syndrome related to fruit and vegetable intake was 1.270 times higher in the deficient group than in the adequate group (p<0.05). Also, when the daily fruit intake was increased by 100 g, the prevalence of metabolic syndrome was reduced by 0.948 times but it was not related to the vegetable intake. The results of this study can be used as the basic data to establish the guidelines for fruit and vegetable intake for prevention of metabolic syndrome in middle-aged men.

Gene Expression in Zn-deficient U937 Cell Line : Using cDNA Microarray (아연결핍된 단핵구 U937 Cell Line에 있어서의 유전자 발현 탐색 : cDNA Microarray 기법 이용)

  • Beattie, John H.;Trayhurn, Paul
    • Journal of Nutrition and Health
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    • v.35 no.10
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    • pp.1053-1059
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    • 2002
  • In post-genome period, the technique for identifying gene expression has been changed to high throughput screening. In the field of molecular nutrition, the need for this technique to clarify molecular function of the specific nutrient is essential. In this study, we have tested the zinc-regulated gene expression in zinc-deficient U937 cells, using cDNA microarray which is the cutting-edge technique to screen large numbers of gene expression simultaneously. The study result can be used for the preliminary gene screening data for clarifying, using monocyte U937 cell line, molecular Zn aspect in atherosclerosis. U937 cells were cultured in Zn-adequate (control, 12 $\mu$M Zn) or Zn-deficient (experimental, 0 $\mu$M Zn) ESMI media during 2 days, respectively. Cells were harvested and RNA was extracted. Total RNA was reverse-transcriptinized and synthesized cDNA probe labeled with Cy-3. fluorescent labeled cDNA probe was applied to microarray slide for hybridization slide, and after then, the slide was scanned using fluorescence scanner. ‘Highly expressed genes’ in Zn-deficient U937 cells, comparing to Zn-adequate group, are mainly about the genes for motility protein, immune system protein, oncogene and tumor suppressor and ‘Less highly expressed genes’ are about the genes for transcription, apoptosis associated protein, cell cycle, and several basic transcription factors. The results of this preliminary study imply the effectiveness of cDNA microarray for expression profiling of a singly nutrient deficiency, specially Zn. Furthur study, using tailored-cDNA array and capillary endothelial cell lines, would be beneficial to clarify molecular Zn function, more in detail.

Force-based seismic design of steel haunch retrofit for RC frames

  • Ahmad, Naveed
    • Earthquakes and Structures
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    • v.20 no.2
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    • pp.133-148
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    • 2021
  • The paper presents a simplified force-based seismic design procedure for the preliminary design of steel haunch retrofitting for the seismic upgrade of deficient RC frames. The procedure involved constructing a site-specific seismic design spectrum for the site, which is transformed into seismic base shear coefficient demand, using an applicable response modification factor, that defines base shear force for seismic analysis of the structure. Recent experimental campaign; involving shake table testing of ten (10), and quasi-static cyclic testing of two (02), 1:3 reduced scale RC frame models, carried out for the seismic performance assessment of both deficient and retrofitted structures has provided the basis to calculate retrofit-specific response modification factor Rretrofitted. The haunch retrofitting technique enhanced the structural stiffness, strength, and ductility, hence, increased the structural response modification factor, which is mainly dependent on the applied retrofit scheme. An additional retrofit effectiveness factor (ΩR) is proposed for the deficient structure's response modification factor Rdeficient, representing the retrofit effectiveness (ΩR=Rretrofitted /Rdeficient), to calculate components' moment and shear demands for the retrofitted structure. The experimental campaign revealed that regardless of the deficient structures' characteristics, the ΩR factor remains fairly the unchanged, which is encouraging to generalize the design procedure. Haunch configuration is finalized that avoid brittle hinging of beam-column joints and ensure ductile beam yielding. Example case study for the seismic retrofit designs of RC frames are presented, which were validated through equivalent lateral load analysis using elastic model and response history analysis of finite-element based inelastic model, showing reasonable performance of the proposed design procedure. The proposed design has the advantage to provide a seismic zone-specific design solution, and also, to suggest if any additional measure is required to enhance the strength/deformability of beams and columns.

Clinical Effect of Gyeongok-go: A Systematic Review of Randomized Controlled Trials (경옥고의 임상 효능 : 체계적 고찰)

  • Kang, Heekyung;Han, Changwoo
    • The Journal of Internal Korean Medicine
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    • v.43 no.3
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    • pp.423-435
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    • 2022
  • Purpose: The purpose of this study was to confirm the clinical efficacy of Gyeongok-go. Methods: Public/Publisher MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), Excerpta Medica dataBASE (EMBASE), Research Information Sharing Service (RISS), ScienceON, Korean Traditional Knowledge Portal (KTKP), and China National Knowledge Infrastructure (CNKI) were searched for randomized controlled clinical trials administering Gyeongok-go as an intervention, published from inception to December 31, 2021. The risk-of-bias of the included trials was assessed with the Cochrane risk-of-bias tool for randomized trials version 2. From the experimental and control groups of the selected trials, the mean value (or rate) of each outcome was extracted and statistically compared. Results: Statistically significant mean differences were in VO2max (MD 6.82), post-exercise heart rate (MD -8.76 at 5 min, -11.58 at 30 min, -14.6 at 60 min), senescence scale (MD -6.52), Th1 cells and Th2 cells in pulmonary tuberculosis (MD 2.79 and -1.64), yin-deficient and qi-deficient score (MD -9.64 and -9.76), and phlegm-dampness score (MD 5.56). Overall risk-of-bias was 20% low risk, 80% some concerns, and 0% high risk. There were no reports of adverse events. Conclusions: Gyeongok-go is likely to have the effect of improving cardiorespiratory endurance, increasing fatigue recovery ability, reducing senescence, and enhancing immune function in tuberculosis patients. Also, it is more suitable for those who are yin-deficient or qi-deficient, and those with phlegm-dampness probably need caution.

Machine Learning-based Rapid Seismic Performance Evaluation for Seismically-deficient Reinforced Concrete Frame (기계학습 기반 지진 취약 철근콘크리트 골조에 대한 신속 내진성능 등급 예측모델 개발 연구)

  • Kang, TaeWook;Kang, Jaedo;Oh, Keunyeong;Shin, Jiuk
    • Journal of the Earthquake Engineering Society of Korea
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    • v.28 no.4
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    • pp.193-203
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    • 2024
  • Existing reinforced concrete (RC) building frames constructed before the seismic design was applied have seismically deficient structural details, and buildings with such structural details show brittle behavior that is destroyed early due to low shear performance. Various reinforcement systems, such as fiber-reinforced polymer (FRP) jacketing systems, are being studied to reinforce the seismically deficient RC frames. Due to the step-by-step modeling and interpretation process, existing seismic performance assessment and reinforcement design of buildings consume an enormous amount of workforce and time. Various machine learning (ML) models were developed using input and output datasets for seismic loads and reinforcement details built through the finite element (FE) model developed in previous studies to overcome these shortcomings. To assess the performance of the seismic performance prediction models developed in this study, the mean squared error (MSE), R-square (R2), and residual of each model were compared. Overall, the applied ML was found to rapidly and effectively predict the seismic performance of buildings according to changes in load and reinforcement details without overfitting. In addition, the best-fit model for each seismic performance class was selected by analyzing the performance by class of the ML models.

The Copper, Cobalt, Iron, Selenium and Zinc Status of Cattle in the Sanyati and Chinamhora Smallholder Grazing Areas of Zimbabwe

  • Mpofu, I.D.T.;Ndlovu, L.R.;Casey, N.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.4
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    • pp.579-584
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    • 1999
  • The trace mineral status of cattle in the smallholder grazing areas of Sanyati and Chinamhora in Zimbabwe was evaluated during the rainy and dry seasons of 1994 and 1995. The evaluation was done in terms of mineral concentration in blood plasma. Plasma copper in calves, steers and cows in the dry season was; Sanyati: 0.55, 0.59, and 0.61; Chinamhora: 0.59, 0.58, and $0.60{\mu}g/ml$, respectively versus a normal of $0.65{\mu}g/ml$. In the rainy season, copper was deficient at both sites (averaging $0.56{\mu}g/ml$ and $0.59{\mu}g/ml$ at Sanyati and Chinamhora, respectively). Plasma selenium in the dry season was 0.017, 0.025, and $0.017{\mu}g/ml$ for calves, steers and cows, respectively at Sanyati versus a normal of $0.03{\mu}g/ml$ and therefore considered to be deficient. Iron, zinc and cobalt were found to be generally high and therefore unlikely to be deficient. Copper and selenium are recommended in salt licks in these environments.

Experimental Assessment of Numerical Models for Reinforced Concrete Shear Walls with Deficient Details (결함 상세를 포함하는 철근콘크리트 전단벽의 수치 모델에 관한 실험적 평가)

  • Jeon, Seong-Ha;Park, Ji-Hun
    • Journal of the Earthquake Engineering Society of Korea
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    • v.20 no.4
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    • pp.211-222
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    • 2016
  • Reinforced concrete shear walls with deficient reinforcement details are tested under cyclic loading. The deficiency of reinforcement details includes insufficient splice length in U-stirrups at the ends of horizontal reinforcement and boundary column dowel bars found in existing low- to mid-rise Korean buildings designed non-seismically. Three test specimens have rectangular, babel and flanged sections, respectively. Flexure- and shear-controlled models for reinforced concrete shear walls specified in ASCE/SEI 41-13 are compared with the flexural and shear components of force-displacement relation extracted separately from the top displacement of the specimen based on the displacement data measured at diverse locations. Modification of the shear wall models in ASCE/SEI 41-13 is proposed in order to account for the effect of bar slip, cracking loads in flexure and shear. The proposed modification shows better approximation of the test results compared to the original models.