• 한방비만학회지
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• 제15권1호
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• pp.9-23
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• 2015

Objectives: This study was investigated the improvement effects of Pakistani Ephedra herba-containing Gangji-hwan-1, 2, 3 (Di-fatty; DF-1, 2, 3), Chinese Ephedra herba-containing Gangjihwan-4 (DF-4) and combination of DF-1 and Gamisoche-hwan (GSH) on obesity in a high fat diet-fed obese mouse model. Methods: Eight-week-old C57BL/6N mice were divided into seven groups: a normal lean group given a standard diet, an obese control group given a high fat diet, and DF-1, 2, 3, 4, and DF-1+GSH groups given a high fat diet with DF-1, 2, 3, 4 (40, 80, 160, 80 mg/kg), and DF-1+ GSH (80 mg/kg), respectively. After 8 weeks of treatment, body weight gain, feeding efficiency ratio (FER), blood lipid markers, liver histology, and fat weight and histology were examined. Results: Body weight gain was significantly decreased in DF and DF-1+GSH groups compared with control. The extent of decreases was eminent in DF-1+GSH group. FER and circulating concentration of leptin were decreased in DF and DF-1+GSH groups compared with control. Circulating concentrations of triglyceride, glucose and insulin were decreased in DF and DF-1+GSH groups compared with control. The size of adipocytes were decreased by DF and DF-1+GSH groups compared with control, whereas the adipocyte number per unit area was increased by them, suggesting that DF and DF-1+GSH groups decreased the number of large adipocytes. Conclusions: In conclusion, these results suggest that DF and DF-1+GSH groups decrease FER, plasma leptin concentration, blood anti-obesity biomarkers and fat mass, improves body weight gain. In addition, these effects were more effective in DF-1+GSH combination group than in DF-1, 2, 3, 4 groups.

• 대한의생명과학회지
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• 제19권3호
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• pp.206-212
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• 2013

The herbal composition Gyeongshingangjeehwan 18 (GGEx18), which is composed of three herbs, Laminaria japonica Aresch (Laminariaceae), Rheum palmatum L. (Polygonaceae), and Ephedra sinica Stapf (Ephedraceae), has been used as an anti-obesity drug in Korean local clinics. Thus, we investigated whether GGEx18 regulates obesity by suppressing appetite in high fat diet-induced obese C57BL/6J mice. Administration of GGEx18 to obese mice for 9 weeks significantly decreased body weight gain, epididymal adipose tissue weight, and food efficiency ratio. GGEx18 also caused a significant decrease in the circulating levels of leptin, which were increased by about 450% in obese control mice compared with normal lean mice. Concomitantly, GGEx18 decreased mRNA levels of a potent appetite-stimulating hormone neuropeptide Y, but increased an appetite-suppressing hormone pro-opiomelanocortin mRNA levels. These results suggest that GGEx18 may prevent obesity through regulating appetite in nutritionally obese mice.

• 대한수의학회지
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• 제1권1호
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• pp.1-29
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• 1961

A routine hematological observation in the course of starvation was carried out on eight experimentel1y starved rabbits. They were strictly selected and restricted all of food intake with the exception of optional water intake until death. The body weight of each rabbit on the day before starvation was about 2 kilograms. The results are summarized as follows. 1. The average decrememt ratio of body weight on the terminal day before death was $34.3{\pm}7.5$ per cent with the range from 24.5 to 46.3 per cent. The average life duration until death was $10.25{\pm}2.6$ days, the range being from 6 to 14 days. 2. The decrease in number of reticulocytes with a parallel disappearance of polychromatic erythrocytes in peripheral blood in the course of starvation Was the most remarkable change in erythrocytic series, an evidence suggesting marked restriction of the erythropoietic function on 3rd to 4th day and almost complete suspension in about a week of starvation. 3. Erythrocyte count, hemoglobin content and haematocrit value of peripheral blood, were normal or indicative of slight hemoconcentration. 4. Mean Corpuscular Hemogloin Concentration was slightly higher than normal and Mean Corpuscular Volume tended to be low and no appreciable shifts were observed in Mean Corpuscular Diameter and Price-Jones curve of erythrocytes, while fewer macrocytes than normal were seen. These changes were considered to have resulted from a marked decrease in young erythrocytes in peripheral blood in the course of starvation. 5. Neither poikilccytoses or anisosytosis was observed. 6. Leukopenia was observed in all of 8 starved rabbits. The decrement ratio on the terminal day of starvation was between 13 to 64 per cent. The leukopenia was mainly due to fall of lymphocytes in 6 cases and to fall of neutrophilic leukocytes in the other 2 cases. In many cases, irregular fluctuation of neutrophilic leukocytes in its biological curve were seen in contrast to the relatively smooth changes of lymphocytes. Eosinophilic leukocytes tended to decrease in absolute number especially in later stage of starvation. Little significance in regard to monocytes and basophilic leukocytes in this study was discussed. 7. Proplasma cells, rarely plasma cells, appeared with a tendency to increase in number at later stage of starvation. 8. The most characteristic changes on circulating blood cells in complete starvation of rabbits were the leukoponia and failure of regeneration of erythroctes. These changes were considered as adaptive phenomena in response to the catabolic consumption of body constituents.

• Asian-Australasian Journal of Animal Sciences
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• 제12권8호
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• pp.1234-1240
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• 1999

The nutritive value of rumen contents and barley mixture (4:1 w/w; RCB) was evaluated and the effect of their feeding on growth performances in Najdi lambs was studied. A metabolism trial was conducted with 16 rams divided into four dietary groups. The diets were: a whole-mixed control diet and three diets where RCB was incorporated at the rates of 25, 50 and 100%, replacing an equal amount of control diet. The results showed that there was a depression (p<0.05) in DM digestibility for the 100% RCB diet in comparison with other diets. The digestibility of CP was higher(p<0.05) for the 25% RCB diet as compared to the control diet; there was a trend for a small (p>0.05) decrease in digestibility as level of RCB increased. Lambs in all studied diets were in positive nitrogen balance; the differences between diets were not significant. A total of 45 lambs were allotted into three groups and used to evaluate the effect of dietary inclusion of RCB (0, 25 and 50%) on growth performance and carcass traits. Daily DM intake, final body weight, carcass weight and dressing percentage were not different among treatments. Average weight gain and ether extract (EE) in 9-11th control joint were higher (p<0.05) in lambs fed control diet than those fed RCB diets. The substitution of RCB for 50% of control diet exhibited 11.8% reduction in feeding cost for each kg of body weight gain.

• 동의생리병리학회지
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• 제22권2호
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• pp.446-452
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• 2008

To evaluate the anti-obesity efficacy of Gamitaeeumjowi-tang consisting of Taeeumjowitang and Daehwang. Eleven male(n=4) and female(n=7), obesity patients were recruited by Tenten Diet Network from November 2005 to February 2006. All the subjects were treated with Gamitaeeumjowi-tang 3 times a day for 12 weeks. Weight, BMI, body fat weight, Total cholesterol, LDL, HDL, Triglycerides, GOT, GPT, and CT results were evaluated before and after the 12 week treatment. Weight, BMI, body fat weight, total cholesterol, triglyceride, and subcutaneous fat in upper and lower abdomen all showed significant decrease after 12 weeks of administration. Also Gamitaeeumjowi-tang showed no toxic effects based on liver function test. Taken together, The potentials of Gamitaeeumjowi-tang as a safe and effective treatment for obesity has been recognized through this study. Further large sample sized and double blinded randomized control trials are needed to fully confirm the findings of this study.

• 한국식생활문화학회지
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• 제33권3호
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• pp.291-298
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• 2018

This study examined the effects of plums produced in Gimcheon area on the glucose and lipid metabolism in streptozotocin-induced diabetic rats. Male Sprague-Dawley diabetic rats were divided into four groups: control, diabetic control, Diabetes-low plum (containing 10% plum powder), and Diabetes-high plum (containing 20% plum powder). The animals were fed isocaloric experimental diets based on an AIN-76 diet for 6 weeks. Feed efficiency ratio (FER) of the diabetic groups were significantly lower than that of the control. On the other hand, among the diabetic groups, the FER of the high plum intake group was higher than that of the diabetic control. The liver weight per 100 g body weight of each group was similar but the liver weights tended to decrease as the amount of plum intake was increased. Kidney weight per 100 g body weight of the plum intake groups were significantly different compared to that of the diabetic control. The supplementation of plums lowered the fasting blood glucose level of the diabetic groups and improved the glucose tolerance, thereby lowering the glycosylated hemoglobin index. In addition, the supplementation of plum was lowered the blood total cholesterol concentration and increased the HDL-C/TC (%) significantly, thereby lowering the atherosclerotic index (AI) and hepatic peroxide level. A steady diet of plums produced in Gimcheon may be effective in controlling the blood glucose level and preventing chronic diabetes mellitus.

• 동의생리병리학회지
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• 제30권3호
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• pp.142-149
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• 2016

This study was designed to investigate the antihyperlipidemic activity of Fermented Rhus Verniciflua Stokes Extract(FRVSE) on diet-induced hyperlipidemia in rats. The animals were divided into 4 groups of the normal group(fed with normal diet), control group(fed with high fat diet), sample A group(fed with high fat diet and medicated FRVSE 192 ㎎/㎏/day), sample B group(fed with high fat diet and medicated FRVSE 384 ㎎/㎏/day), and received oral administration of each prescription with diet for a period of six weeks. The changes in the body weight, the liver weight, the epididymal fat weight, and the plasma levels of total cholesterol, triglyceride(TG), high density lipoprotein(HDL) cholesterol and low density lipoprotein(LDL) cholesterol were measured. In sample A group, the weight of liver and plasma level of TG decreased significantly. There was a significant decrease in the plasma level of total cholesterol, TG and LDL cholesterol in the sample B group. These results suggest that the FRVSE have a good antihyperlipidemic activity and a potential to treat hyperlipidemia.

• International Journal of Internet, Broadcasting and Communication
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• 제14권4호
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• pp.222-227
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• 2022

The purpose of this study was to investigate changes in heart rate according to recovery methods after circuit weight training exercise. Fourteen men in their twenties were selected as subjects, and three sets of circuit weight training were performed by cycling six sports, and two recovery conditions (dynamic and static) were performed immediately after exercise. Changes in heart rate did not have an interactive effect according to recovery method and time, and both conditions showed significant changes between sets 1 and 2, and between sets 3 and after recovery. In this study, the high heart rate of 2 sets and 3 sets was seen as a result of exercise stimulation, and the low heart rate of 1 set was thought to be due to the decrease in vagus nerve activity rather than the role of catecholamines. On the other hand, the heart rate after 20 minutes of exercise did not show any difference according to the recovery method, which could mean that the recovery process due to the aquatic environment can act more strongly than the process of dynamic recovery and static recovery. It is thought that the characteristics affected the sensory and circulation of the body, and thus the change of the afferent signal and the level of metabolic products generated in the active muscle.

• 한국재난정보학회 논문집
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• 제14권3호
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• pp.343-351
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• 2018

연구목적: 최근 기반시설물이 대형화 됨에 따라 콘크리트 구조물의 경우는 중량감소를 위하여 중공 슬래브가 대안의 하나로 제시되고 있다. 연구방법: 중공부재의 시공 시 부력으로 인하여 시공이 어려운 점과 콘크리트 단면적이 줄어 전단성능이 부족하게 되는 구조적인 단점이 있으므로, PVC관과 같은 중공체를 이용하여 일방향 슬래브를 제작하고 시공성과 구조성능을 검토하는 실험을 실시하였다. 연구결과: PVC관을 이용한 일방향 중공슬래브의 경우 부력방지장치를 이용하면 타설 시 발생하는 중공체의 부상 및 침강을 예방하여 시공성능이 크게 개선되었으며, 휨 및 전단성능도 적합한 성능을 가진 것으로 확인되었다. 결론: 중공율과 휨성능은 큰 관계가 없지만 중공율이 큰 경우는 항복 후 2차 강성이 낮으므로 이에 대한 고려가 필요하며, 중공율의 증가에 따른 전단성능의 감소는 전단철근을 배근하면 보완될 수 있을 것으로 사료된다.

• International Journal of Advanced Culture Technology
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• 제6권4호
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• pp.205-213
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• 2018

This research is about effects of obesity adults participating in 12weeks of boxing diets program on weight loss, blood pressure and blood sugar improvements. The exercise program was conducted three times a week with a maximum heart rate of 50 to 65 percent for first to forth weeks and 65 to 85 percent for fifth to twelfth. The study included 59 obese people in their 20s and 50s, with a BMI of 25kg/m2 or higher, blood pressure of 140/90mmHg, and high blood pressure and diabetes patients of 125 mg/dl per fasting blood sugar. The following results were obtained by observing the results before and after the boxing exercise program. High blood pressure, diabetes, high blood pressure + diabetes after 12 weeks showed significant weight, BMI and body fat reduction, as well as significant decrease in blood pressure and fasting blood sugar. Consequently, through this study, obese adults can lower their weight, blood pressure, and blasting fasting blood sugar through a 12-week high-strength boxing exercise program and it is believed to help improve and prevent obesity, cardiovascular disease and metabolic diseases.