This study provides an empirical analysis based on 2012 Korea Innovation Survey (STEPI) to investigate the relation between R&D cooperation and in-house R&D investment. The study further analyzes the effect of the R&D cooperation and in-house R&D investment on technical innovation. First, the relation between company's in-house R&D investment and R&D cooperations is estimated with the two equations using SUR models. Second, the effect of in-house R&D investment and R&D cooperation on the company's technical innovation is estimated using Probit model. This study differs from other existing R&D studies using Korean data in that empirical models are based on structural relationships among in-house R&D, R&D cooperation, and technical innovation. The results can be summarized as follows; the R&D cooperation expands the in-house R&D investment and the in-house R&D strengthen the R&D cooperation. Furthermore, In-house R&D investment increases the chances of success in innovation. As we obtain evidence of complementary relation between R&D cooperation and in-house R&D investment, it is necessary to develop environment conducive to this complementarity in order to have more efficient R&D system.
Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.
Today, businesses have to respond with flexibility and speed to ever-changing customer demand and market opportunities. Service-oriented architecture (SOA) is the best methodology for minimizing the complexity and the cost of enterprise-level infrastructure and for maximizing the productivity and the flexibility of an enterprise. Most of the enterprise-level SOA delivery strategies deal with the top-down approach, which organization has to define the business processes, to model business services, and to find the required services or to develop new services. However, a lot of peoples want to maximally reuse legacy component-based systems as well as to deliver SOA into their organizations. In this paper, we propose a bottom-up approach for identifying business services with proper granularity. It can improve the reusability and maintenance of services by considering not data I/O of components of legacy applications but GUI event patterns. Our proposed method is applied to MIS with 129 GUIs and 13 components. As a result, the valiance of the coupling value of components is increased five times and three business services are distinctly exposed. It also provides a 49% improvement in reducing the relationship problems between services over a service identification method using only partitioning information of components.
This paper proposes a new indexing mechanism for MPEG-7 visual descriptors, especially Dominant Color and Contour Shape descriptors, that guarantees an efficient similarity search for the multimedia database whose visual meta-data are represented with MPEG-7. Since the similarity metric used in the Dominant Color descriptor is based on Gaussian mixture model, the descriptor itself could be transform into a color histogram in which the distribution of the color values follows the Gauss distribution. Then, the transformed Dominant Color descriptor (i.e., the color histogram) is indexed in the proposed indexing mechanism. For the indexing of Contour Shape descriptor, we have used a two-pass algorithm. That is, in the first pass, since the similarity of two shapes could be roughly measured with the global parameters such as eccentricity and circularity used in Contour shape descriptor, the dissimilar image objects could be excluded with these global parameters first. Then, the similarities between the query and remaining image objects are measured with the peak parameters of Contour Shape descriptor. This two-pass approach helps to reduce the computational resources to measure the similarity of image objects using Contour Shape descriptor. This paper also proposes two integration schemes of visual descriptors for an efficient retrieval of multimedia database. The one is to use the weight of descriptor as a yardstick to determine the number of selected similar image objects with respect to that descriptor, and the other is to use the weight as the degree of importance of the descriptor in the global similarity measurement. Experimental results show that the proposed indexing and integration schemes produce a remarkable speed-up comparing to the exact similarity search, although there are some losses in the accuracy because of the approximated computation in indexing. The proposed schemes could be used to build a multimedia database represented in MPEG-7 that guarantees an efficient retrieval.
Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
/
v.20
no.7
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pp.46-52
/
2006
The effects of surface treatment on the hydrogen storage properties of a $Mg_2Ni$ alloy particle were investigated by the microvoltammetric technique, in which a carbon-filament microelectrode was manipulated to make electrical contact with the particle in a KOH aqueous solution. It was found that the hydrogen storage properties of $Mg_2Ni$ at room temperature were improved by the surface treatment with a nickel plating solution. The sodium salts(sodium phosphate and sodium dihydrogen citrate) contained in the nickel plating solution made the alloy form an amorphous-like state, resulting in an improved hydrogen charge/discharge capacity at room temperature as high as about 150[mAh/g] from the original value of 17[mAh/g]. Potential-step experiment was carried out to determine the apparent chemical diffusion coefficient of hydrogen atom($D_{app}$) in the alloy. Since the alloy particle we used here was a dense, conductive sphere, the spherical diffusion model was employed for data analysis. $D_{app}$ was found to vary the order between $10^{-8}{\sim}10^{-9}[cm^2/s]$ over the course of hydrogenation and dehydrogenation process.
Joint Collaborative Team on Video Coding (JCT-VC), which have founded ISO/IEC MPEG and ITU-T VCEG, has standardized High Efficiency Video Coding (HEVC). Standardization of HEVC has started with purpose of twice or more coding performance compared to H.264/AVC. However, flexible and hierarchical coding block and recursive coding structure are problems to overcome of HEVC standard. Many fast encoding algorithms for reducing computational complexity of HEVC encoder have been proposed. However, it is hard to implement a real-time HEVC encoder only with those fast encoding algorithms. In this paper, for implementation of software-based real-time HEVC encoder, data-level parallelism using SIMD instructions and CPU/GPU multi-threading methods are proposed. And we also proposed appropriate operations and functional modules to apply the proposed methods on HM 10.0 software. Evaluation of the proposed methods implemented on HM 10.0 software showed 20-30fps for $832{\times}480$ sequences and 5-10fps for $1920{\times}1080$ sequences, respectively.
On, Noori;Kim, Nam-Gyu;Ru, Kimyoung;Jang, Hanbichnale;Lee, Jongsuk Ruth
Journal of Internet Computing and Services
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v.20
no.6
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pp.85-93
/
2019
Computational Science and Engineering is a convergence study that understands and solves complex problems such as science, engineering, and social phenomena through modeling using computing resources. Computational science and engineering combines algorithms, computational and informatics, and infrastructure. The importance of computational science is increasing with the improvement of computer performance and the development of large data processing technology. In Korea, Korea Institute of Science and Technology Information (KISTI) has been developing national computational science engineering software and utilization technology by combining basic science and computing technology through EDISON project. The EDISON project builds an open EDISON platform and integrates and services information systems in seven areas of computational science and engineering (computational thermal fluids, nanophysics, computational chemistry, structural dynamics, computational design, and computational medicine). Using this, we have established a web-based curriculum to lay the groundwork for fostering scientific talent and commercializing computational science and engineering software. The purpose of this study is to derive the quality characteristic factors of computational science platform and to empirically examine the effect on user satisfaction. This paper examines how the quality characteristics of information systems, the computational science engineering platform, affect the user satisfaction by modifying the research questions according to the propensity of the computational science platform by referring to the success factors of DeLone and McLean's information system. Based on the results of this study, we will suggest strategic implications for platform improvement by searching the priority of quality characteristics of computational science platform.
This study identified the health habits affecting health status of industrial workers. Data was collected from 965 workers in 58 companies at Buchon. The research conducted a self-administered questionnaire survey and obtained the workers' health examination records. The results were as follows: 1. Among 965 respondents, men were 82.4%, women were 17.6%, 44.5% were of the 30${\sim}$40 age group, the married were 67.4%, the single were 30.8%, high school graduates were 81.1% and 38.8% were of people who worked between 1 and 5 years 2. As far as the seven health habits, current smokers were 52.8%, people who regularly exercise was 28.5%, 7${\sim}$8 hour of sleep, on the average were 71.4%, people eating breakfast nearly every day were 8.8%, and people eating between meals almost every day were 46.5%. Heavy drinkers who drink 3${\sim}$4 times or more per week were 14.2%, 1${\sim}$2 times per week were 32.6% and the obese were 9.3%. 3, Health status of A and B, estimated by doctors in the health examination were 80.8% and C, D1, D2, the unhealthy were 19.2%. For men, those who reported more than women in unhealthy groups and the results regarding health status reflects those for gender, educational level and age. That is to say that, lower educational level group and over 30 years of age group perceive their health to be worse than the higher educational level and under 30 age group. And these differences were statistically significant. 4. The relationship between health habits and health status were examined based on the odds ratio. Current smokers had a consistently worse health status than a non smokers with a 1.98 odds ratio. The workers who reported eating breakfast rarely or never were more associated with the unhealthy group than the regular breakfast eating group with a 2.96 odds ratio. One or more drink per week had a worse health status than a never or a little drinker with a 1.56 odds ratio. 5. General health habit score and duration of work were selected as significant factors influencing health status from the result of logistic regression analysis. According to the results of this model, the odds ratio of good health status was 2.08 for good health habit score, 1.63 for workers who worked five years or more duration at work. In summary, good health habits were associated with good health status. In particular, the workers who had 5 or more desirable health habits had a significantly better health status than the workers who had 4 or less than 4 good health habits. Therefore, in order to provide the health promotion programs to workers it is necessary to organize clear health management plans based on effective health education and health service perspective. If further research examines health habits and health status using a prospective study design, More precise findings for health promotion program development in the worksite and worksite health management planning.
A trading system is a computer trading program that automatically submits trades to an exchange. Mechanical a trading system to execute trade is spreading in the stock market. However, a trading system to trade a single asset might occur instability of the profit because payoff of this system is determined a asset movement. Therefore, it is necessary to develop a trading system that is trade two assets such as a pair trading that is to sell overvalued assets and buy the undervalued ones. The aim of this study is to propose a relative value based trading system designed to yield stable and profitable profits regardless of market conditions. In fact, we propose a procedure for building a trading system that is based on the rough set analysis of indicators derived from a price ratio between two assets. KOSPI 200 index futures and S&P 500 index futures are used as a data for evaluation of the proposed trading system. We intend to examine the usefulness of this model through an empirical study.
Molecular reorientation in (NH$_4$)$_2$SO$_4$, has been studied by cold neutron scattering. For T=300$^{\circ}$K data, the isolated quasielastic spectra and form-factors at various scattering angles are compared with four reorientational models based on SKOLD theory. Front these, it is concluded that the NH$_4$ions are performing either 3-fold four axes or 2-fold three axes reorientation with $\tau$$_{c}$=2.0$\times$10$^{-11}$ sec. The temperature dependence of f. is studied over 100$^{\circ}$K-413$^{\circ}$K and for the high-temperature phase, the widths of composite spectra are compared with the results from NMR relaxation measurements. All the results have shown that the neutron scattering method is capable of giving detalis of the reorientational modes in solids and therefore some discussions are given on the application of this method. A study of the form-factor is applied for NH$_4$I (Phase I) by comparing the measurement with the calculation based on free rotation approximation and proposed a reorientation model of NH$_4$ ions in the octahedral potential cage with $\tau$$_{c}$$\leq$10$^{-12}$ sec. Also a brief theoretical prediction for the effect of reorientational motions on the inelastic spectrum is discussed.sed.
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