• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.12 no.6
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• pp.629-635
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• 2019

In Deep Learning models derivative is implemented by error back-propagation which enables the model to learn the error and update parameters. It can find the global (or local) optimal points of parameters even in the complex models taking advantage of a huge improvement in computing power. However, deliberately generated data points can 'fool' models and degrade the performance such as prediction accuracy. Not only these adversarial examples reduce the performance but also these examples are not easily detectable with human's eyes. In this work, we propose the method to detect adversarial datasets with random noise addition. We exploit the fact that when random noise is added, prediction accuracy of non-adversarial dataset remains almost unchanged, but that of adversarial dataset changes. We set attack methods (FGSM, Saliency Map) and noise level (0-19 with max pixel value 255) as independent variables and difference of prediction accuracy when noise was added as dependent variable in a simulation experiment. We have succeeded in extracting the threshold that separates non-adversarial and adversarial dataset. We detected the adversarial dataset using this threshold.

• Journal of Korean Society of Forest Science
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• v.101 no.3
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• pp.365-373
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• 2012

This study purposed to extract and assess the accuracy of assessment for deforestation area in Wonju city using medium resolution satellite image. The total size of deforestation area during the last nine years (2000-2008) was about 467 ha, and it was occurred annually about 52 ha. The most frequent form of deforestation was settlements (72%). Ninety percent of the size of deforestation was less than 2 ha in size. In addition, 79 percent of deforestation area was found within 500 m from the road network and within 100 m of the Forest/Non-forest boundary. This study compared the deforestation based on the administrative information (GIS deforestationI) with the deforestation (RS deforestation) extracted from the satellite imagery by vegetation indices (NDVI, NBR, NDWI). Extraction accuracy, mean-standard deviation${\times}1.5$ applied 3 by 3 filtering, showed reliable accuracy 35.47% k-value 0.20. However, error could be occurred because of the difference of land-use change and land-cover change. The actual rate of land-cover change deforestation area was 32% on administrative information. The 7.52% of forest management activities area was misjudged as deforestation by RS deforestation. Finally, the comparison of land-cover change deforestation (GIS deforestationII) with the RS deforestation accuracy, as a result NDVI mean-standard deviation${\times}2$ applied 3 by 3 filtering, showed improved accuracy 61.23%, k-value 0.23.

• The Journal of Korean Medicine
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• v.30 no.5
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• pp.88-101
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• 2009

Objectives: Since Korean traditional medicine has an integrative perspective by its nature, the patients' psychological and physical problems in a Korean traditional clinic may be resolved through a more integrative approach. The purpose of this study was to describe the latent characteristics of psychological health of child outpatients and their parents visiting Korean traditional clinic with physical complaints and was to propose an alternative curriculum to meet their needs based on their psychological and physical aspects. Methods: Subjects studied consisted of 100 outpatients (59 boys, 41 girls, mean age 55 months, age range 18 to 83 months) and their parents. Behavior characteristics for children were measured by Korean version of Child Behavior Checklist for Ages 1.5-5 (CBCL1.5-5) while parenting stress, depression, and anxiety for parent were measured by Korean-Parenting Stress Index-Short Form (K-PSI-SF), Center for Epidemiologic Studies Depression Scale (CES-D) and State-Trait Anxiety Inventory (STAI), respectively. The data of subjects were compared to those of standardized groups and then were compared according to child's gender within sample. Results: Child participants were reported to have significantly higher scores of all CBCL 1.5-5 subscales than the standardized group. When compared, no differences of K-PSI-SF, CES-D, and STAI was found between parents of participants and the standardized groups. However, parents of child participants with at-risk psychological problems showed significantly higher scores of all parenting stress subscales than those of all child participants. In addition, the mothers of boy participants demonstrated significantly higher anxiety, depression and parenting stress than those of girl participants irrespective of psychological severity. Conclusions: We discussed the implication of these results in clinical situation and make recommendations for curriculum of psychiatry and pediatrics with the aim of improving proper diagnosis, consulting and treatment.

• Journal of Distribution Science
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• v.14 no.12
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• pp.107-118
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• 2016

Purpose - In today's markets, new technologies such as social network systems and user generated contents have provided consumers with access to unlimited amounts of information and an ability to communicate with other consumers in the world. Specially, the massive of the internet and the development of online communities and interactive platforms offer the potential to cocreate with a large number of consumers. Significant changes in marketplace suggest that simply being consumer oriented is not enough, so firms must learn from and collaborate with consumers to create values that meet their individual and dynamic needs. In these sense, emergent perspectives in marketing highlight new opportunities for co-opting consumers as a means to define and cocreate value through their engagement. Although the importance of consumer co-creation with firms, the current literature lacks the respond to two questions: (1) who are the most competent consumers for creating the values with firm? and (2) what are the stimulaters to help the consumers engage for co-creation? To this answer the question, this research investigate how to structure consumer motivations to encourage consumers to be more engaged for co-creation and what drives a consumer to get involved to respond to a call for co-creation. Research design, data, and methodology - To empirically test the hypotheses, a survey was conducted among consumers who had experienced the co-creation including upstream, downstream, autonomous, and sponsored co-creation with the firms. We collected a total of 343 responses. After we excluded 37 questionnaire because of incomplete responses, a total of 306 questionnaire remained. Working with a sample of 306 responses in Seoul and Kwangju, hierarchical moderated regression is employed to test research hypotheses. Results - The results indicated that consumer creativity and emergent nature are positively related to engagement in co-creation including upstream, downstream, autonomous, and sponsored co-creation. Also, the relationships between consumer creativity/emergent nature and engagement in co-creation were moderated by intrinsic motivation in case of upstream and downstream co-creation. Finally, interaction effects between consumer creativity/emergent nature and extrinsic motivation were not significant. Conclusions - These results suggest that marketing managers have to consider the consumer personality such as creativity and emergent nature and stimulate the intrinsic motivation of consumer to achieve the co-creation project successfully.

• Journal of the Korean Institute of Intelligent Systems
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• v.20 no.1
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• pp.7-14
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• 2010

In this paper, we introduce a hierarchical internet application traffic classification system based on SVM as an alternative overcoming the uppermost limit of the conventional methodology which is using the port number or payload information. After selecting an optimal attribute subset of the bidirectional traffic flow data collected from the campus, the proposed system classifies the internet application traffic hierarchically. The system is composed of three layers: the first layer quickly determines P2P traffic and non-P2P traffic using a SVM, the second layer classifies P2P traffics into file-sharing, messenger, and TV, based on three SVDDs. The third layer makes specific classification of the entire 16 application traffics. By classifying the internet application traffic finely or coarsely, the proposed system can guarantee an efficient system resource management, a stable network environment, a seamless bandwidth, and an appropriate QoS. Also, even a new application traffic is added, it is possible to have a system incremental updating and scalability by training only a new SVDD without retraining the whole system. We validate the performance of our approach with computer experiments.

• IMMUNE NETWORK
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• v.6 no.1
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• pp.27-32
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• 2006

Background: Chronic inflammation in the brain has known to be associated with the development of a various neurological diseases including dementia. In general, the characteristic of neuro-inflammation is the activated microglia over the brain where the pathogenesis occurs. Pro-inflammatory repertoires, interleukin-1${\beta}$ (IL-1${\beta}$) and nitric oxide (NO), are the main causes of neuro-degenerative disease, particularly in Alzheimer's disease (AD) which is caused by neuronal destruction. Those pro-inflammatory repertoires may lead the brain to chronic inflammatory status, and thus we hypothesized that chronic inflammation would be inhibited when pro-inflammatory repertoires are to be well controlled by inactivating the signal transduction associated with inflammation. Methods: In the present study, we examined whether biphenyl dimethyl dicarboxylate (DDB), an active compound from Schizandra chinensis Baillon, inhibits the NO production by a direct method using Griess reagent and by RT-PCR in the gene expression of inducible nitric oxide synthase (iNOS) and IL-1${\beta}$. Western blots were also used for the analysis of NF-${\kappa}B$ and I${\kappa}B$. Results: In the study, we found that DDB effectively inhibited IL-1${\beta}$ as well as NO production in BV-2 microglial cell, and the translocation of NF-${\kappa}B$ was comparably inhibited in the presence of DDB comparing those to the positive control, lipopolysaccharide. Conclusion: The data suggested that the DDB from Schizandra chinensis Baillon may play an effective role in inhibiting the pro-inflammatory repertoires which may cause neurodegeneration and the results imply that the compound suppresses a cue signal of the microglial activation which can induce the brain pathogenesis such as Alzheimer's disease.

• IMMUNE NETWORK
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• v.6 no.3
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• pp.154-162
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• 2006

Background: Dendritic cell (DC)-based cancer immunotherapy is studied for several years. However, it is mainly derived from autologous PBMC or leukapheresis from patient, which has limitations about yield and ability of DC production according to individual status. In order to solve these problems, inquiries about allogeneic DCs are performed but there are no preclinical trial answers for effect or toxicity of allogeneic DC to use for clinical trial. In this study, we compared the anti-tumor effect of allogeneic and autologous DCs from mouse bone marrow stem cells in mouse metastatic melanoma model. Methods: B16F10 melanoma cells ($5{\times}10^4$/mouse) were injected intravenously into the C57BL/6 mouse. Therapeutic DCs were differentiated from autologous (C57BL/6: CDC) or allogeneic (B6C3F1: BDC) bone marrow stem cells with GM-CSF, SCF and IL-4 for 13days and pulsed with B16F10 tumor cell lysate (Blys) for 18hrs. DC intra-peritoneal injections began on the 8th day after the tumor cell injection by twice with one week interval. Results: Anti-tumor response was observed by DC treatment without any toxicity especially in allogeneic DC treated mice (tumor burden score: $2.667{\pm}0.184,\;2.500{\pm}0.463,\;2.000{\pm}0.286,\;1.500{\pm}0.286,\;1.667 {\pm}0.297$ for saline, CDC/unpulsed-DC: U-DC, CDC/Blys-DC, BDC/U-DC and BDC/Blys-DC, respectively). IFN-${\gamma}$ secretion was significantly increased in allogeneic DC group stimulated with B16F10 cell lysate ($2,643.3{\pm}5,89.7,\;8,561.5{\pm}2,204.9.\;6,901.2{\pm}141.1pg/1{\times}10^6$ cells for saline, BDC/U-DC and BDC/Blys-DC, respectively) with increased NK cell activity. Conclusion: Conclusively, promising data was obtained that allogeneic DC can be used for DC-based cancer immunotherapy.

• IMMUNE NETWORK
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• v.6 no.1
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• pp.33-42
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• 2006

Background: Calcineurin plays a crucial role in T cell activation, cell growth, apoptosis, and angiogenesis, and its over-expression has been implicated in the pathogenesis of cardiomyopathy and stroke. However, the expression and function of calcineurin in the pathologic lesion of chronic inflammatory diseases, like rheumatoid synovium, remain to be defined. This study was aimed to determine the role of calcineurin in inflammatory arthritis and investigate the expression and function of calcineurin in the rheumatoid synovium and synoviocytes, the actual site of chronic inflammation. Methods: Immuno-histochemical staining using specific antibody to calcineurin was perfomed in the synovium of rheumatoid arthritis (RA). Fibroblast-like synoviocytes (FLS) from RA and osteoarthritis (OA) patients were isolated from RA and OA patients, and cultured with IL-1${\beta}$ and TNF-${\alpha}$ in the presence or absence of cyclosporin A, a calcineurin inhibitor. The calcineurin expression was assessed by phosphatase assay and Western blotting analysis. IL-6, -10, -17, matrix metalloproteinase (MMP)-1, -2, -3, and -9 released into the culture supernatants were measured by ELISA. After transfection with GFP-Cabin 1 gene into synoviocytes, the levels of IL-6 and MMPs were measured by ELISA. Results: Calcineurin was highly expressed in the lining layer of synovium and cultured synoviocytes of RA patients. The elevated calcineurin activity in the rheumatoid synoviocytes was triggered by proin flammatory cytokines such as IL-1${\beta}$ and TNF-${\alpha}$. In contrast, IL-10, an anti-inflammatory cytokine, failed to increase the calcineurin activity. The targeted inhibition of calcineurin by the over-expression of Cabin 1, a natural calcineurin antagonist, inhibited the production of IL-6 and MMP-2 by rheumatoid synoviocytes in a similar manner to the calcineurin inhibitor, cyclosporin A. Conclusion: These data suggest that abnormal activation of calcineurin in the synoviocytes may contribute to the pathogenesis of chronic arthritis, and thus provide a potential target for controlling inflammatory arthritis.

• Korean Journal of Human Ecology
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• v.18 no.4
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• pp.841-855
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• 2009

The main objective of this study is to examine the situations of group-homes for the elderly and clarify the problems of them. This study investigates the present conditions of welfare facilities and supply conditions. 4 group-homes were surveyed in Jeonju and Kwangju cities. Data was collected through various ways including the survey conducted by facility operators, the measurement of living space, and photo-takings. The major results of this study are as follows: 1) With the introduction of nursing care insurance in 2008, the increase of the demand and supply to group-home will be expected, due to less cost for recuperation. The care of elderly in homelike atmosphere is effective to the elderly suffering from dementia. Therefore, it is proper that the supply of group-homes for dementia will be needed. 2) Group-homes for the elderly are being supplied under the standards of welfare facilities in the present. Separate supply standards, however, are needed because they are not suitable for small scale group-homes. 3) To supply Group-homes for the elderly on a one-unit basis would cause various problems such as economical unreality, personnel distribution and so on. It is necessary to supply more than two units for more efficient management. 4) The management of group-homes for the elderly is financially unstable because the operating funds heavily depend on the users or people who are connected with the facilities through private networks. Therefore, additional support is needed to settle the financial problem. It would be helpful to build the public networking that provides information about the group-home for the elderly for the public. 5) In case of the increase in the supply of the group-home in a residential area, it could be helpful to promote the group-home to the public. 6) The operators state that the main problems of group homes for the elderly lie in financial difficulties and the shortage of professionals and volunteers. The financial, personnel, and material support for personnel and the supervision of management are required for the transparency and effectiveness of the facility management. In addition, the closer network and cooperation system with the community is required. 7) The present living environments for group-homes for the elderly leave much room for improvement, considering the physical condition of the elderly. The more careful selections in the color, shape, material, and equipment of the facilities should be made for the convenience of the elderly users.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.6
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• pp.27-36
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• 2015

The purpose of this study was to investigate the influence relationships among individual career orientation, preparation of old age, social networks, and the entrepreneurial intention of the potential entrepreneurs. 408 numbers of structured questionnaire were collected from the potential entrepreneurs who live in Seoul through the online Google survey method and offline face to face method. And the collected data was analyzed on frequency analysis, validity analysis, t-test, ANOVA, and regression analysis etc. using the SPSS WIN 21.0 program. The results are as follows. Firstly, innovation, entrepreneurial creativity, and autonomy orientation affect on entrepreneurial intention positively(+), but security orientation has a negative(-) effect on entrepreneurial intention in the influence relationships between individual career orientation and entrepreneurial intention. Secondly, economical and emotional preparation have positive(+) influences on entrepreneurial intention in the influence relationships between individual career orientation and entrepreneurial intention. Thirdly, the sub-variables of social networks, that is, assist and role models exert a positive(+) influence on entrepreneurial intention in the influence relationships between social networks and entrepreneurial intention. Fourthly, social networks plays a moderating role only on the relationship between security orientation and entrepreneurial intention in the analysis about the moderating effects of social networks on the influence relationships among individual career orientation, preparation of old age, and entrepreneurial intention. Fifth, a social network of relationships to help prepare the old establishment has been found to help regulate effective analysis of whether or not the results of adjustment.