• Biomolecules & Therapeutics
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• v.30 no.2
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• pp.170-178
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• 2022

The airway epithelium is equipped with the ability to resist respiratory disease development and airway damage, including the migration of airway epithelial cells and the activation of TLR3, which recognizes double-stranded (ds) RNA. Primary cilia on airway epithelial cells are involved in the cell cycle and cell differentiation and repair. In this study, we used Beas-2B human bronchial epithelial cells to investigate the effects of the TLR3 agonist polyinosinic:polycytidylic acid [Poly(I:C)] on airway cell migration and primary cilia (PC) formation. PC formation increased in cells incubated under serum deprivation. Migration was faster in Beas-2B cells pretreated with Poly(I:C) than in control cells, as judged by a wound healing assay, single-cell path tracking, and a Transwell migration assay. No changes in cell migration were observed when the cells were incubated in conditioned medium from Poly(I:C)-treated cells. PC formation was enhanced by Poly(I:C) treatment, but was reduced when the cells were exposed to the ciliogenesis inhibitor ciliobrevin A (CilioA). The inhibition of Beas-2B cell migration by CilioA was also assessed and a slight decrease in ciliogenesis was detected in SARS-CoV-2 spike protein (SP)-treated Beas-2B cells overexpressing ACE2 compared to control cells. Cell migration was decreased by SP but restored by Poly(I:C) treatment. Taken together, our results demonstrate that impaired migration by SP-treated cells can be attenuated by Poly(I:C) treatment, thus increasing airway cell migration through the regulation of ciliogenesis.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.89-89
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• 2022

Soybean (Glycine max (L.) Merr.) is a representative food resource. To preserve the integrity of soybean, it is necessary to protect soybean yield and seed quality from threats of various pests and diseases. Riptortus pedestris is a well-known insect pest that causes the greatest loss of soybean yield in South Korea. This pest not only directly reduces yields but also causes disorders and diseases in plant growth. Unfortunately, no resistant soybean resources have been reported. Therefore, it is necessary to identify the distribution and movement of Riptortus pedestris at an early stage to reduce the damage caused by insect pests. Conventionally, the human eye has performed the diagnosis of agronomic traits related to pest outbreaks. However, due to human vision's subjectivity and impermanence, it is time-consuming, requires the assistance of specialists, and is labor-intensive. Therefore, the responses and behavior patterns of Riptortus pedestris to the scent of mixture R were visualized with a 3D model through the perspective of artificial intelligence. The movement patterns of Riptortus pedestris was analyzed by using time-series image data. In addition, classification was performed through visual analysis based on a deep learning model. In the object tracking, implemented using the YOLO series model, the path of the movement of pests shows a negative reaction to a mixture Rina video scene. As a result of 3D modeling using the x, y, and z-axis of the tracked objects, 80% of the subjects showed behavioral patterns consistent with the treatment of mixture R. In addition, these studies are being conducted in the soybean field and it will be possible to preserve the yield of soybeans through the application of a pest control platform to the early stage of soybeans.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.23 no.1
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• pp.112-122
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• 2024

Recently, as unmanned aerial vehicle technology such as drones has developed, there are many environmental, social and economic benefits, but if there is malicious intent against important national facilities such as airports, public institutions, power plants, and the military, it can seriously affect national safety and people's lives. It can cause damage. To respond to these drone threats, attempts are being made to introduce detection equipment such as RF scanners. In particular, power transmission towers installed in substations, power plants, and Korea's power system can affect detection performance if the transmission tower is located in the RF scanner detection path. In the experiment, a commercial drone was used to measure the signal intensity emitted from the drone and confirm the attenuation rate. The average and maximum attenuation rates showed similar trends in the 2.4 GHz and 5.8 GHz bands, and were also affected by the density of the structure.

• Journal of Advanced Navigation Technology
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• v.27 no.6
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• pp.877-883
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• 2023

For safe operation of ships and management of marine fisheries farms, the data set that extracts the boundaries of marine fisheries farms can provide information on obstacles in the vessel's navigation path in advance by examining whether it matches the fishing ground permit area. In addition, it can be used to determine whether fish farms are operating to compensate for damage caused by marine accidents, and the relevant local government can use it to manage fishing grounds. It is also highly utilized as basic data to identify obstacles for safe navigation of ships. In this study, Sentinel-2 satellite image data from the European Space Agency (ESA) was used to extract the boundaries of fish farms. From the video image, the fish farm's status data by cycle was divided into five zones: Busan-Ulsan area, Geoje-Changwon area, Goseong-Tongyeong area, and Namhae-Sacheon area. Through the image highlighting process, the farm boundary data and meta data were processed and extracted.

• Journal of the Korean Society of Propulsion Engineers
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• v.2 no.2
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• pp.14-23
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• 1998

The present study investigates numerically particle laden flow through compressor cascade. In general, a lot of turbine engines are affected by various particles which are suspending in the atmosphere. Especially in the case of aircraft aviating in volcanic, industrial and desert region including many particles, each components of engine system are damaged severely. That damage modes are erosion of compressor binding and rotor path components, partial or total blockage of cooling passage and engine control system degradation.. Initial damages can not be serious but cumulation of damages influences on safety of aircraft control and economical maintenance cost of engine system can be increased. When dust, materials and volcanic particles in the atmosphere flow in the compressor, it is necessary to predict damaged and deposited region of compressor blades. To the various flow inlet angle, predictions of particles trajectory in compressor cascade by Lagrangian method are presented and impulses by impaction of particles at blade surface are calculated. By the definition of particle deposition efficiency, characteristics of particles impact are considered quantitatively. With these prediction and experimental data, erosion rates are predicted for two materials - ceramic, soft metal - on compressor blade surface. Improvements like coating of blade surface could be found, by above prediction.

• Journal of the Korean Association of Geographic Information Studies
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• v.13 no.4
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• pp.125-137
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• 2010

Jongmyo royal shrine, located in Seoul, is a UNESCO World Heritage site, and a cultural relic of national value and significance. Examination of its udobakseok(granitic flagstone; thin, flat and even stepping-stones for the King) has shown that parts are in damaged condition. In this study, GIS and GPS technologies were applied to determine the extent of damage and to find granitic flagstone for replacement and restoration of the damaged stones. 1,158 out of 2,361 stone pieces of the udobakseok were damaged at Jongmyo. Replacement granitic flagstones are available on Seokmo Island, in Ganghwa County, and estimates show that approximately 100,000 pieces of stone can be quarried. This research aided the systematic management of information about availability and location of granitic flagstones for restoration of the Jongmyo udobakseok. It also demonstrated that GIS and GPS technologies can apply a critical role in managing cultural properties. The wide use of GIS and GPS technologies can be expected for survey and management of other cultural properties in addition to Jongmyo.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.3
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• pp.395-406
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• 2018

The XP-SWMM model, widely used for inundation analysis of urban watersheds, underestimated the inundation area (range) because the manhole was regarded as a node and the influence of the local loss occurring in the surcharged manhole can not be considered. Therefore, it is necessary to analyze the applicability of the head loss coefficients considering the local loss in the surcharged manholes in inundation analysis using XP-SWMM. The Dorim 1 drainage section of the Dorim-river watershed, where frequent domestic flood damage occurred, was selected as the study watershed. The head loss coefficients of the surcharged manholes estimated from the previous experimental studies were applied to the inundation analysis, and the changes of the inundation area with and without the application of the head loss coefficients with manhole types were compared and analyzed. As a result of inundation simulation with the application of head loss coefficients, the matching rates were increased by 17% in comparison with the without application of them. In addition, the simulated inundation area applied only the head loss coefficients of straight path manholes and applied up to the head loss coefficients of combining manholes ($90^{\circ}$ bend, 3-way, and 4-way) were similar. Therefore, in order to accurately simulate the storm drain system in urban areas, it could be to carry out two-dimensional inundation analysis considering the head loss coefficients at the surcharged manholes. It was expected that the study results will be utilized as basic data for establishing the identification of the inundation risk area.

• Journal of Korean Neurosurgical Society
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• v.61 no.3
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• pp.363-375
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• 2018

Intraoperative monitoring (IOM) utilizes electrophysiological techniques as a surrogate test and evaluation of nervous function while a patient is under general anesthesia. They are increasingly used for procedures, both surgical and endovascular, to avoid injury during an operation, examine neurological tissue to guide the surgery, or to test electrophysiological function to allow for more complete resection or corrections. The application of IOM during pediatric brain tumor resections encompasses a unique set of technical issues. First, obtaining stable and reliable responses in children of different ages requires detailed understanding of normal age-adjusted brain-spine development. Neurophysiology, anatomy, and anthropometry of children are different from those of adults. Second, monitoring of the brain may include risk to eloquent functions and cranial nerve functions that are difficult with the usual neurophysiological techniques. Third, interpretation of signal change requires unique sets of normative values specific for children of that age. Fourth, tumor resection involves multiple considerations including defining tumor type, size, location, pathophysiology that might require maximal removal of lesion or minimal intervention. IOM techniques can be divided into monitoring and mapping. Mapping involves identification of specific neural structures to avoid or minimize injury. Monitoring is continuous acquisition of neural signals to determine the integrity of the full longitudinal path of the neural system of interest. Motor evoked potentials and somatosensory evoked potentials are representative methodologies for monitoring. Free-running electromyography is also used to monitor irritation or damage to the motor nerves in the lower motor neuron level : cranial nerves, roots, and peripheral nerves. For the surgery of infratentorial tumors, in addition to free-running electromyography of the bulbar muscles, brainstem auditory evoked potentials or corticobulbar motor evoked potentials could be combined to prevent injury of the cranial nerves or nucleus. IOM for cerebral tumors can adopt direct cortical stimulation or direct subcortical stimulation to map the corticospinal pathways in the vicinity of lesion. IOM is a diagnostic as well as interventional tool for neurosurgery. To prove clinical evidence of it is not simple. Randomized controlled prospective studies may not be possible due to ethical reasons. However, prospective longitudinal studies confirming prognostic value of IOM are available. Furthermore, oncological outcome has also been shown to be superior in some brain tumors, with IOM. New methodologies of IOM are being developed and clinically applied. This review establishes a composite view of techniques used today, noting differences between adult and pediatric monitoring.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.2
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• pp.423-430
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• 2013

Recently, the personal identification technologies using vein pattern of back of the hand, palm, and finger have been developed actively because it has the advantage that the vein blood vessel in the body is impossible to damage, make a replication and forge. However, it is difficult to extract clearly the vein region from captured vein images through common image prcessing based region segmentation method, because of the light scattering and non-uniform internal tissue by skin layer and inside layer skeleton, etc. Especially, it takes a long time for processing time and makes a discontinuity of blood vessel just in a image because it has non-uniform illumination due to use a locally different adaptive threshold for the binarization of acquired finger-vein image. To solve this problem, we propose illumination normalization based fast method for extracting the finger-vein region. The proposed method has advantages compared to the previous methods as follows. Firstly, for remove a non-uniform illumination of the captured vein image, we obtain a illumination component of the captured vein image by using a low-pass filter. Secondly, by extracting the finger-vein path using one time binarization of a single threshold selection, we were able to reduce the processing time. Through experimental results, we confirmed that the accuracy of extracting the finger-vein region was increased and the processing time was shortened than prior methods.

• Korean Journal of Remote Sensing
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• v.30 no.1
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• pp.127-136
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• 2014

When the mouth of the Nakdong River, opens its floodgate, thousands of tons of litter should flown into the South Sea, moving towards nearby coast, thus causing serious social and economic damage. For this reason, in the present study, research was performed on one certain area in northeast coast of Geoje island, which is assumed as area damaged due to rainy season and typhoon in 2012, and research for trace of movement route was implemented by using buoy to identify characteristic of movement of floating debris caused from Nakdong River. Flows related to the movement of floating debris was also identified by analyzing ocean meteorological environment. As a result of the study, total 40 tons of litter composed of grasses and trees(or plants litter) were flown into Heungnam beach on 16th, Jul which is the rainy season. Plus, the location tracking buoy, which was dropped when the typhoon SANBA was coming, was passed by southern sea of Gadeok-do and was flown into Geoje beach 1 ~ 2 days after it was dropped. The wind direction was mostly northeasterly wind around the Geoje beach at the time the buoy and floating debris were flown into northeast coast and there was common sea surface currents which was flowing into the coast.