• 제목/요약/키워드: damage level

검색결과 2,981건 처리시간 0.025초

간경(肝經)의 형화혈(滎火穴)과 합수혈(合水穴)에 시술한 레이저침이 D-GalN 간손상 유발 흰쥐에 미치는 영향 (Effects of Low Level Laser Treatment at LR2 and LR8 acupoint on the liver damage induced in D-GalN in rats)

  • 김왕인;윤대환;최찬헌;나창수
    • Korean Journal of Acupuncture
    • /
    • 제29권1호
    • /
    • pp.131-141
    • /
    • 2012
  • Objectives : This study was performed to investigate the effect of invasive laser acupuncture treatment at Liver Brook (LR2) acupoint and Liver Sea (LR8) acupoint on liver damage induced by D-galactosamine (D-GalN) in rats Methods : Liver damage was induced by D-GalN. The experimental rats were divided into two groups (control group, Low Level Laser Treatment (LLLT) group). Control groups were classified into small groups. Intact group had no liver damage and no treatment. D-GalN group was induced liver damage induced by D-GalN and not treated. LLLT group were induced liver damage induced by D-GalN and then treated at the LR2 or LR8 acupoint with 532, 658, 904 nm invasive laser acupuncture. The treatment was carried out three days at a time for 15days at both acupoints. To examine mechanism of the effect of invasive laser acupuncture, we measured the contents of ASP, ALT, ALP, TBIL in serum, CBC in blood and SOD in liver tissue. Results : The change of body weight increased in all groups. That change was AST and ALP, the AST activity decreased significantly compared with the control groups and decreased by 532 nm and 904 nm both LLLT groups. But ALP increased at LR8 acupoint by 658 nm. TBIL level significantly decreased in all LLLT groups. The SOD of LLLT groups increased in the liver tissue of rats compared to the control groups. SOD activity indicated that LLLT can help cellular defense mechanism by preventing scavenging hydrogen peroxide. In the change of WBC, it was increased in D-GalN Control group compared to intact group and LLLT groups. Conclusions : These results suggested that invasive laser acupuncture treatment at LR2 or LR8 acupoint reduced activation of hepatic enzyme and damage of liver tissue. Thus, the effect of invasive laser acupuncture was nearly identical to the way of the traditional acupuncture for the treatment of hepatocytotoxicity.

연속형 변수 회귀분석을 통한 열수송관 파손빈도 분석 (Continuous Variable Regression Analysis for Frequency of Damage Analysis in Heat Pipe)

  • 공명식;강재모;이성열
    • 한국지반환경공학회 논문집
    • /
    • 제24권12호
    • /
    • pp.47-52
    • /
    • 2023
  • 지역난방사업자가 운영하는 열수송관의 효율적인 유지관리를 위해 사업자가 구축한 설비이력 및 파손이력 데이터를 활용하여 파손발생과 연관성을 가지는 주요 독립변수를 확인한 후, 파손빈도와의 상관관계를 분석하고, 파손빈도 추정을 위한 기본모델을 도출하였다. 국내외 지역난방사업자가 기존에 활용 중인 사용기간 기반의 추정 모델과의 연관성을 고려하여 사용기간 뿐만 아니라 관경, 매설깊이, 감시시스템 절연레벨 등 연속형 변수와 파손빈도의 상관성이 가장 높은 독립변수로 단순회귀분석 기본모델을 제시하였으며, 나머지 독립변수는 기본모델을 수정, 보완하는 인자로 반영하였다. 분석 결과 기존 연구사례와 마찬가지로 사용기간과 파손빈도간 분석 모델의 적합성과 두 변수간 상관성이 가장 높은 것으로 확인되어 기본모델로 활용 가능하다. 관경, 매설깊이, 감시시스템 절연레벨 정보 역시 파손빈도와의 상관성이 확인되어 기본모델을 보완하기 위한 인자로 활용 가능하다.

시공단계의 진동레벨 단위적용에 관한 사례 연구 (A Case Study on the Application of Vibration Level Units in the Construction Phase)

  • 최형빈;김동연
    • 화약ㆍ발파
    • /
    • 제30권2호
    • /
    • pp.86-97
    • /
    • 2012
  • 건설현장의 노천발파로 발생되는 지반진동은 인체의 간접피해 및 구조물의 물적 피해를 동반하며, 인체는 진동레벨, 구조물은 진동속도 단위로 평가한다. 본 연구는 실시단계 진동기준 중 진동속도 외 누락된 진동레벨 단위를 추가, 진동속도 및 진동레벨을 동시 측정한 적용사례로서 추후 민원이 예상되는 현장관리에 도움이 될 것으로 여겨진다. 발파진동 및 진동레벨 추정식 도출을 위한 표본수는 총 232개가 사용되었으며, 진동속도 0.3 cm/s와 진동레벨 75 dB(V) 기준의 지발당장약량을 비교한 결과, 후자가 20.0~40.9% 여유가 있음을 입증하여 진동레벨 단위척도 추가는 전혀 문제되지 않음을 언급하였다. 소음 진동 관리법이 우선된다면 노천발파 시공비용은 훨씬 저감될 것으로 생각된다. 본 연구에서 사용된 계측기기는 국내에서 처음으로 진동속도 및 진동레벨을 동시 측정할 수 있는 특성을 지닌 SV-1모델을 사용하였다.

동결피해 후의 수확시기가 사과 '후지' 품종의 저장 중 과실품질에 미치는 영향 (Influence of Harvest Time after Freezing Damage on Fruit Quality during Storage of 'Fuji' Apples)

  • 권헌중;이상규;박무용;송양익;남종철;사공동훈
    • 원예과학기술지
    • /
    • 제28권6호
    • /
    • pp.990-995
    • /
    • 2010
  • 본 시험은 이상저온($-3.5^{\circ}C$ 이하에서 7시간 지속)에 의해 수체 상에서 동결된 사과 '후지' 과실들의 수확시기에 따른 품질차이를 비교하고자 실시하였다. 수확 시기는 동결피해 1일 전, 동결피해 2일 후, 동결피해 6일 후였다. 시험에 조사된 과실들의 수확시 가용성 고형물 함량은 $14^{\circ}Bx$ 이상이었다. 동결피해 후 수확한 과실의 수확 시 경도 및 산 함량은 동결피해 전에 수확한 과실보다 낮았다. 저온저장 중의 에틸렌 발생량은 동결피해 후 수확한 과실이 동결피해 전에 수확한 과실보다 높았다. 동결피해 후 수확한 과실의 저온 저장 동안의 품질저하는 동결피해 전에 수확한 과실보다 심하였다. 동결피해 후에 수확한 과실의 저온저장 출고 후 실온 1주일째의 품질 저하는 동결피해 전에 수확한 과실보다 더 심하였다. 동결피해 후에 수확한 시험구들간의 비교에서는 저온저장 8주까지 동결피해 6일 후에 수확한 시험구의 에틸렌 발생량 및 과실품질 저하가 동결피해 2일 후에 수확한 시험구보다 낮았으나, 이러한 차이는 저온저장 8주 이후로는 없었다. 과육 갈변증상 발생률은 $-3.5^{\circ}C$ 이하에서 7시간 동결될 경우 영향을 받지 않은 것으로 나타났다.

철도건널목 사고방지를 위한 지능화 방안 연구 (Accident prevention and damage reduction technology development through intelligence of Highway-railroad grade crossing)

  • 조봉관;류상환;황현철;조흥식;이호용
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2008년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
    • /
    • pp.175-177
    • /
    • 2008
  • The level crossing collision accident which comprises more than 90 percent of all level crossing accidents is one of the most serious safety problems. There is a critical need for providing safe strategy and is focusing on the level crossing information rather than measures at a grade crossing. This study is intended to develop technology for accident prevention and damage reduction based on accident cases analysis result and improvement direction to complement shortcomings of safety equipment of conventional level crossing and to establish safety of travelers(train, motor vehicle, person).

  • PDF

해양사고 피해규모에 의한 위험수준 평가 (Evaluation of Risk Level for Damage of Marine Accidents in SRRs using Fuzzy Theory)

  • 장운재;금종수
    • 한국항해항만학회:학술대회논문집
    • /
    • 한국항해항만학회 2004년도 춘계학술대회 논문집
    • /
    • pp.145-150
    • /
    • 2004
  • This paper suggests an evaluation of risk level for damage of marine accidents in SRRs. Qualitative analyses in words is sometimes priorior to quantative analyses in numeric symbols. This paper intoduces a concept of fuzzy theory with the plenty of related literature riview and AHP in the Korean SRRs of RCC and RSC. The methodology of this paper is maxㆍmin composition of fuzzy extensive principle, defuzzifiation is centroid of gravity methods. At the result, the evaluation of risk level is especially over Serous for smarine accident of Taean, Gunsan, Mokpo, Yosu, Tongyoung, Busan SRR. This paper recommends that many Resale Vessels and Equipments need to the reduction of risk level about those.

  • PDF

DNA damage와 Apoptosis를 정량화하는 단세포전기영동법 (Single Cell Gel Electrophoresis (comet assay) to Detect DNA Damage and Apoptosis in Cell Level)

  • 류재천;김현주;서영록;김경란
    • 한국환경성돌연변이발암원학회지
    • /
    • 제17권2호
    • /
    • pp.71-77
    • /
    • 1997
  • The single cell gel electrophoressis(SCGE) assay, also known as the comet assay, is a rapid, simple, visual and sensitive technique for measuring and analysing DNA breakage in mammalian cells. The SCGE or comet assay is a promising test for the detection of DNA damage and repair in individnal cells. It has widespread potential applications in DNA damage and repair studies, genotoxicity testing and biomonitoring. In this microgel electrophoresis technique, cells are embedded in agarose gel on microscope slides, iysed and electrophoresed under alkaline conditions. Cells with increased DNA damage display increased migration of DNA from the nucleus towards the anode. The length of DNA migration indicates the amount of DNA breakage in the cell. The comet assay is also capable of identifying apoptotic cells which contain highly fragmented DNA. Here we review the development of the SCGE assay, existing protocols for the detection and analysis of comets, the relevant underlying principles determining the behaviour of DNA and the potential applications of the technique.

  • PDF

복합적층재의 온도에 의한 저속충격특성 (Effect of Temperature on Low Velocity Impact Characteristics of Composite Laminates)

  • 한영욱;김후식;김재훈;이영신;조정미;박병준
    • 한국복합재료학회:학술대회논문집
    • /
    • 한국복합재료학회 2002년도 춘계학술발표대회 논문집
    • /
    • pp.93-96
    • /
    • 2002
  • Instrumented impact tests and compression-after-impact(CAI) tests have been used to evaluate the effect of temperature on the low-velocity impact characteristics of phenolic matrix composites reinforced with various woven glass fabric. Impact characteristics and damage area in laminates are evaluated by C-scan. It is shown that the extent of damage and residual compressive strength of the laminates vary with energy level and impact test temperature. The damage area increases with increasing impact energy and temperature. All these observations indicate reduced impact damage resistance and damage tolerance of the laminates at elevated temperature.

  • PDF

Multi-stage approach for structural damage identification using particle swarm optimization

  • Tang, H.;Zhang, W.;Xie, L.;Xue, S.
    • Smart Structures and Systems
    • /
    • 제11권1호
    • /
    • pp.69-86
    • /
    • 2013
  • An efficient methodology using static test data and changes in natural frequencies is proposed to identify the damages in structural systems. The methodology consists of two main stages. In the first stage, the Damage Signal Match (DSM) technique is employed to quickly identify the most potentially damaged elements so as to reduce the number of the solution space (solution parameters). In the second stage, a particle swarm optimization (PSO) approach is presented to accurately determine the actual damage extents using the first stage results. One numerical case study by using a planar truss and one experimental case study by using a full-scale steel truss structure are used to verify the proposed hybrid method. The identification results show that the proposed methodology can identify the location and severity of damage with a reasonable level of accuracy, even when practical considerations limit the number of measurements to only a few for a complex structure.

페난트렌에 의한 임파구 DNA의 산화적 손상과 인삼추출물에 의한 억제 (Phenanthrene-induced Oxidative DNA Damage of Lymphocytes and the Suppression by Ginseng Extract)

  • 유아름;이미영
    • Journal of Ginseng Research
    • /
    • 제33권4호
    • /
    • pp.355-360
    • /
    • 2009
  • Phenanthrene ($C_{14}H_{10}$) is a polycyclic aromatic hydrocarbon with three aromatic rings, and it can be produced by incomplete combustion of fossil fuels. Comet assay was used to examine the oxidative DNA damage of lymphocytes by phenanthrene and to measure the suppressive effects of ginseng extract on the DNA damage in this investigation. The in vitro oxidative DNA damage by phenanthrene increased in a dose-dependent manner in the lymphocyte. However, the DNA damage was significantly inhibited by ascorbate. Moreover, pretreatment, cotreatment and posttreatment with ginseng extract enhanced lymphocyte resistance to the phenanthrene-induced DNA damage. Phenanthrene enhanced the generation of intracellular reactive oxygen species, and the elevated reactive oxygen species level was reduced by treatment with ginseng extract.