• Journal of the Korean Mathematical Society
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• v.36 no.4
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• pp.747-756
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• 1999

In ring theory it is well-known that a ring R is (von Neumann) regular if and only if all right R-modules are flat. But the analogous statement for this result does not hold for a monoid S. Hence, in sense of S-acts, Liu (]10]) showed that, as a weak analogue of this result, a monoid S is regular if and only if all left S-acts satisfying condition (E) ([6]) are flat. Moreover, Bulmann-Fleming ([6]) showed that x is a regular element of a monoid S iff the cyclic right S-act S/p(x, x2) is flat. In this paper, we show that the analogue of this result can be held for automata and them characterize regular semigroups by flat automata.

• Structural Engineering and Mechanics
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• v.24 no.3
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• pp.355-374
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• 2006

Thin walled steel bridge-piers/columns are vulnerable to damage, when subjected to earthquake excitations. Local buckling, global buckling or interaction between local and global buckling usually is the cause of this damage, which results in significant strength reduction of the member. In this study new innovative design concepts, "thin-walled corrugated steel columns" and "thin-walled cellular steel columns" are presented, which allow the column to undergo large plastic deformations without significant strength reduction; hence dissipate energy under cyclic loading. It is shown that, compared with the conventional designs, circular and stiffened box sections, these new innovative concepts might results in cost-effective designs, with improved buckling and ductility properties. Using a finite element model, that takes the non-linear material properties into consideration, it is shown that the corrugations will act like longitudinal stiffeners that are supporting each other, thus improving the buckling behavior and allowing for reduction of the overall wall thickness of the column.

• Structural Engineering and Mechanics
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• v.64 no.2
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• pp.195-204
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• 2017

Analytical and experimental studies of the innovative pipe in pipe damper have been recently investigated by the authors. In this paper, by adding lead or zinc infill or slit diaphragm inside the inner pipe, it is tried to increase the equivalent viscous damping ratio improving the cyclic performance of the recently proposed multi-level control system. The damper consists of three main parts including the outer pipe, inner pipe and added complementary damping part. At first plastic deformations of the external pipe, then the internal pipe and particularly the added core and friction between them make the excellent multi-level damper act as an improved energy dissipation system. Several kinds of added lead or zinc infill and also different shapes of slit diaphragms are modeled inside the inner pipe and their effectiveness on hysteresis curves are investigated with nonlinear static analyses using finite element method by ABAQUS software. Results show that adding lead infill has no major effect on the damper stiffness while zinc infill and slit diaphragm increase damper stiffness sharply up to more than 10 times depending on the plate thickness and pipe diameter. Besides, metal infill increases the viscous damping ratio of dual damper ranging 6-9%. In addition, obtained hysteresis curves show that the multi-level control system as expected can reliably dissipate energy in different imposed energy levels.

• Bulletin of the Korean Chemical Society
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• v.33 no.4
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• pp.1225-1230
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• 2012

A new unsymmetrical zinc phthalocyanine has been designed and synthesized based on the 'push-pull' and extended ${\pi}$-conjugation concept for the dye-sensitized solar cells. Three tert-butoxy groups, which act as electron releasing ('push'), enhance the solubility of phthalocyanine in common organic solvents and reduce the aggregation. Hydroxy substituted 9,10-anthraquinones act as electron acceptors ('pull') for the study of photoinduced electron transfer processes as well as grafting onto nanocrystalline $TiO_2$. The new unsymmetrical zinc phthalocyanine was fully characterized by FTIR, UV-vis, $^1H$ NMR, cyclic voltammetry and differential pulse voltammetry. The new sensitizer was tested in dye-sensitized solar cells, and gave a better performance.

• Steel and Composite Structures
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• v.42 no.6
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• pp.827-841
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• 2022

The rotation capacities of the plastic hinges located at beam-ends are significantly reduced in traditional steel framed-tube structures (SFTSs) because of the small span-to-depth ratios of the deep beams, leading to the low ductility and energy dissipation capacities of the SFTSs. High-strength steel framed-tube structures with replaceable shear links (HSSFTS-RSLs) are proposed to address this issue. A replaceable shear link is located at the mid-span of a deep spandrel beam to act as a ductile fuse to dissipate the seismic energy in HSSFTS-RSLs. A 2/3-scaled HSSFTS-RSL specimen with a shear link fabricated of high-strength low-alloy Q355 structural steel was created, and a cyclic loading test was performed to study the hysteresis behaviors of this specimen. The test results were compared to the specimens with soft steel shear links in previous studies to investigate the feasibility of using high-strength low-alloy steel for shear links in HSSFTS-RSLs. The effects of link web stiffener spaces on the cyclic performance of the HSSFTS-RSLs with Q355 steel shear links were investigated based on the nonlinear numerical analysis. The test results indicate that the specimen with a Q355 steel shear link exhibited a reliable and stable seismic performance. If the maximum interstory drift of HSSFTS-RSL is designed lower than 2% under earthquakes, the HSSFTS-RSLs with Q355 steel shear links can have similar seismic performance to the structures with soft steel shear links, even though these shear links have similar shear and flexural strength. For the Q355 steel shear links with web height-to-thickness ratios higher than 30.7 in HSSFTS-RSLs, it is suggested that the maximum intermediate web stiffener space is decreased by 15% from the allowable space for the shear link in AISC341-16 due to the analytical results.

• Journal of Korean Society of Steel Construction
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• v.25 no.1
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• pp.47-59
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• 2013

This study that is a successive secondary study right after the primary bending strength test of a new form of U-shape hybrid composite beam is a cyclic seismic test of U-shape hybrid composite beam and column conncetion. Three specimens are built for the variables which are kinds of columns, depth of beam, continuity or discontinuity of upper plate of beam, and a number of steel bars of end-beam. Kinds of columns are a reinforcement concrete column and a ACT column of CFT shape, and beam depth are 300, and 500 mm. Detail of connection is bolt connection with using a short bracket that is commonly use. As the result, deformability of 2~4% is ensured the floor displacement angle. If it is the negative moment, the maximum moment shows that its capacity is above the nominal moment.

• Journal of the Earthquake Engineering Society of Korea
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• v.11 no.1 s.53
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• pp.29-35
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• 2007

Flexural capacity estimation test of concrete filled carbon tube (CFCT) column under the cyclic lateral load was carried out in this study. Thickness of carbon tube and winding angles of carbon fiber were chosen as test parameters and two types of column with square and circular sections were manufactured. To act axial and lateral load, three dynamic actuators were used and all specimens were made with actual size. Flexural stiffness, ability of deformation, energy dissipation capacity and ductility behavior. of CFCT column were analyzed with test data.

• Oncology Letters
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• v.41 no.1
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• pp.361-368
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• 2019

Gliomas, the most highly malignant central nervous system tumors, are associated with an extremely poor patient survival rate. Given that gliomas are derived from mutations in glial precursor cells, a considerable number of them strongly react with glial precursor cell-specific markers. Thus, we investigated whether malignant gliomas can be converted to glial cells through the regulation of endogenous gene expression implicated in glial precursor cells. In the present study, we used three small-molecule compounds, [cyclic adenosine monophosphate (cAMP) enhancer, a mammalian target of rapamycin (mTOR) inhibitor, and a bromodomain and extra-terminal motif (BET) inhibitor] for glial reprogramming. Small-molecule-induced gliomas (SMiGs) were not only transformed into exhibiting a glial-specific morphology, but also showed positive reactions with glial-specific markers such as glial fibrillary acidic protein (GFAP), 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP) and anti-oligodendrocyte (RIP). A microarray analysis indicated that SMiGs exhibited a marked increase in specific gene levels, whereas that of a malignant cancer-specific gene was greatly decreased. Moreover, proliferation of the cells was markedly suppressed after the conversion of malignant glioma cells into glial cells. Our findings confirmed that malignant gliomas can be reprogrammed to non-proliferating glial cells, using a combination of small molecules, and their proliferation can be regulated by their differentiation. We suggest that our small-molecule combination (with forskolin, rapamycin and I-BET151) may be the next generation of anticancer agents that act by reprogramming malignant gliomas to differentiate into glial cells.

• BMB Reports
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• v.40 no.5
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• pp.678-683
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• 2007

Extracts from the leaves of the Ginkgo biloba are becoming increasingly popular as a treatment that is claimed to reduce atherosclerosis, coronary artery disease, and thrombosis. In this study, the effect of ginkgolide B (GB) from Ginkgo biloba leaves in collagen (10 ${\mu}g/ml$)-stimulated platelet aggregation was investigated. It has been known that human platelets release matrix metallo-proteinase-9 (MMP-9), and that it significantly inhibited platelet aggregation stimulated by collagen. Zymographic analysis confirmed that pro-MMP-9 (92-kDa) was activated by GB to form an MMP-9 (86-kDa) on gelatinolytic activities. And then, activated MMP-9 by GB dose-dependently inhibited platelet aggregation, intracellular $Ca^{2+}$ mobilization, and thromboxane $A_2$ ($TXA_2$) formation in collagen-stimulated platelets. Activated MMP-9 by GB directly affects down-regulations of cyclooxygenase-1 (COX-1) or $TXA_2$ synthase in a cell free system. In addition, activated MMP-9 significantly increased the formation of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), which have the anti-platelet function in resting and collagen-stimulated platelets. Therefore, we suggest that activated MMP-9 by GB may increase the intracellular cAMP and cGMP production, inhibit the intracellular $Ca^{2+}$ mobilization and $TXA_2$ production, thereby leading to inhibition of platelet aggregation. These results strongly indicate that activated MMP-9 is a potent inhibitor of collagen-stimulated platelet aggregation. It may act a crucial role as a negative regulator during platelet activation.

• Journal of Korean Society of Steel Construction
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• v.23 no.3
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• pp.317-326
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• 2011

Today there is a growing range of applications for Concrete-Filled Steel Tube (CFT) member because of its superior performance. Ductility estimation test of concrete-filled seismic resistant steel tubular columns, subjected to axial and cyclic lateral load, was carried out in this study. Seismic resistant steel tubes are manufactured using SN400B plates by a two-seam welding at center of the column width for cold press-formed shape plates of two pieces. A total of eight specimens were manufactured and tested with the parameters of width-thickness ratio of steel tubular column, axial load ratio, and loading conditions to act axial and cyclic lateral load two dynamic actuators were used. From test results, flexural strength, deformation capacity, energy dissipation capacity, and ductility behavior of columns were analyzed.