• The Korean Journal of Physiology and Pharmacology
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• 제23권3호
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• pp.219-227
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• 2019

Polycystic kidney disease 2-like-1 (PKD2L1), polycystin-L or transient receptor potential polycystin 3 (TRPP3) is a TRP superfamily member. It is a calcium-permeable non-selective cation channel that regulates intracellular calcium concentration and thereby calcium signaling. Although the calmodulin (CaM) inhibitor, calmidazolium, is an activator of the PKD2L1 channel, the activating mechanism remains unclear. The purpose of this study is to clarify whether CaM takes part in the regulation of the PKD2L1 channel, and if so, how. With patch clamp techniques, we observed the current amplitudes of PKD2L1 significantly reduced when co-expressed with CaM and $CaM{\triangle}N$. This result suggests that the N-lobe of CaM carries a more crucial role in regulating PKD2L1 and guides us into our next question on the different functions of two lobes of CaM. We also identified the predicted CaM binding site, and generated deletion and truncation mutants. The mutants showed significant reduction in currents losing PKD2L1 current-voltage curve, suggesting that the C-terminal region from 590 to 600 is crucial for maintaining the functionality of the PKD2L1 channel. With PKD2L1608Stop mutant showing increased current amplitudes, we further examined the functional importance of EF-hand domain. Along with co-expression of CaM, ${\triangle}EF$-hand mutant also showed significant changes in current amplitudes and potentiation time. Our findings suggest that there is a constitutive inhibition of EF-hand and binding of CaM C-lobe on the channel in low calcium concentration. At higher calcium concentration, calcium ions occupy the N-lobe as well as the EF-hand domain, allowing the two to compete to bind to the channel.

• The Korean Journal of Physiology and Pharmacology
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• 제2권2호
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• pp.165-172
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• 1998

Under certain pathophysiological conditions, such as inflammation and ischemia, the concentration of H^+$ ion in the tissue surrounding neurons is changed. Variations in H^+$ concentration are known to alter the conduction and/of the gating properties of several types of ion channels. Several types of K^+$ channels are modulated by pH. In this study, the whole cell configuration of the patch clamp technique has been applied to the recording of the responses of change of external pH on the delayed rectifier K^+$ current of cultured DRG neurons of rat. Outward K^+$ currents were examined in DRG cells, and the Charybdotoxin and Mn^{2+}$ could eliminate Ca^{2+}-dependent$ K^+$ currents from outward K^+$ currents. This outward K^+$ current was activated around -60 mV by step depolarizing pulses from holding potential -70 mV. Outward K^+$ currents were decreased by low external pH. Activation and steady-state inactivation curve were shifted to the right by acidification, while there was small change by alkalization. These results suggest that H^+$ could be alter the sensory modality by changing and modifying voltage-dependent K^+$ currents, which participated in repolarization.

• 한국정보통신학회논문지
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• 제11권3호
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• pp.570-576
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• 2007

본 연구에서는 field-dependent polarization 모델과 square-law FET 모델을 이용하여 Metal- ferroelectic-semiconductor FET (MFSFET) 소자의 특성을 연구하였다. 게이트 전압에 따른 드레인 전류특성에서 강유전체 박막의 항전압이 0.5 와 1 V 일 때, 각각 1와 2 V의 메모리 창 (memory window) 을 나타내었다. 드레인 전류-드레인 전압곡선에서 두 부분의 문턱전압에 의해 나타난 포화 드레인 전류차이는 게이트 전압이 0, 0.1, 0.2, 0.3 V 일 때, 각각 1.5, 2.7, 4.0, 5.7 mA로 명확한 차이를 나타내었다. PLZT(10/30/70), PLT(10), PZT(30/70) 박막의 이력곡선 시뮬레이션과 리텐션 특성의 fitting 결과를 바탕으로 시간경과 후의 드레인 전류를 분석한 결과, PLZT(10/30/70) 박막이 10년 후에도 약 18%의 포화 전류가 감소하는 가장 우수한 신뢰성을 나타내었다.

• 반도체디스플레이기술학회지
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• 제21권4호
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• pp.138-143
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• 2022

We analyzed the influence of post-annealing on Ga₂O₃/n-type 4H-SiC heterojunction diode. Gallium oxide (Ga₂O₃) thin films were deposited by radio frequency (RF) sputtering. Post-deposition annealing at 950℃ in an Oxygen atmosphere was performed. The material properties of Ga₂O₃ and the electrical properties of the diodes were investigated. Atomic Force Microscopy (AFM), X-Ray Diffraction and Scanning Electron Microscope (SEM) images show a significant increase in the roughness and crystallinity of the O₂-annealed films. After Oxygen annealing X-ray Photoelectron Spectroscopy (XPS) shows that the atomic ratio of oxygen increases which is related to a decrease in oxygen vacancy within the Ga₂O₃ film. The O₂-annealed diodes exhibited higher on-current and lower leakage current. Moreover, the ideality factor, barrier height, and thermal activation energy were derived from the current-voltage curve by increasing the temperature from 298 - 434K.

• 공업화학
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• 제33권1호
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• pp.96-102
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• 2022

고분자전해질막 연료전지의 반응물인 수소와 산소는 기체 상태이므로, 반응물이 원활히 전달될수록 작동 전압의 손실을 줄일 수 있다. 높은 전류밀도 영역에서 산소 물질 전달이 전압 손실을 좌우하므로, 환원극 유로의 형상 변경에 대한 연구들이 진행되어 왔다. 환원극 유로 형상 중에서 유로를 막는 블록은 반응물을 다공성 매질인 기체확산층으로 강제 대류 하도록 사용되었다. 본 연구에서는 간단한 단 채널의 연료전지 모델에 블록을 배치하였다. 전산 유체역학을 사용하였고, 공기 공급 유량을 달리하였을 때 블록으로 인한 강제 대류 효과가 전압-전류 곡선과 국부 전류 밀도에 대한 영향을 연구하였다. 기체확산층으로의 강제 대류 현상을 통하여 적은 공기 공급 유량으로도 높은 전류 밀도를 얻을 수 있었다. 다수의 블록을 직렬로 배치한 경우에 1개의 블록만 배치한 것보다 강제 대류 효과를 증가시켜 높은 전류밀도를 얻을 수 있었다.

• 한국항공우주학회지
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• 제38권5호
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• pp.507-517
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• 2010

대한항공 기술연구원은 한국과학기술원 인공위성연구센터의 과학기술위성 2호 태양전지 배열기 비행모델을 순수 국내기술로 개발하고, 그 성능을 발사환경시험, 궤도환경시험 그리고 모사 태양광 조사 시험을 통해 검증하였다. 개발된 태양전지 배열기가 탑재된 과학기술위성 2호는 국내 최초의 소형위성 발사체인 KSLV-I에 탑재되어 2010년 5월 나로우주센터에서 발사될 예정이며, 발사 후 위성 운용 데이터를 통해 저궤도에서의 개발된 국산 태양전지 배열기의 우주 인증을 수행할 예정이다. 본 연구에서는 과학기술위성 2호 태양전지 배열기의 전력 성능에 영향을 미치는 요소들을 태양전지 등가모델에 적용하여 태양전지 배열기의 전력 특성을 나타내는 전류-전압 곡선을 도출하고, 이를 모사 태양광 조사를 통한 성능 시험 결과와 비교함으로써 태양전지 등가 모델 및 전력 성능 시뮬레이션의 적합성을 검증하였다. 본 논문의 태양전지 배열기 등가 모델 및 전력 성능 시뮬레이션은 과학기술위성 2호의 관제 운용에 있어, 전 임무기간 동안 생성 전력용량에 따른 최적의 부하운용에 사용될 수 있을 것으로 예상된다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 추계학술대회 논문집 Vol.19
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• pp.172-173
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• 2006

Metal-ferroelectric-insulator-semiconductor (MFIS) structures with $Bi_{3.35}La_{0.75}Ti_3O_{12}$ (BLT) ferroelectric film and Zirconium oxide ($ZrO_2$) layer were fabricated on p-type Si(100). $ZrO_2$ and BLT films were prepared by sol-gel technique. Surface morphologies of $ZrO_2$ and BLT film were measured by atomic force microscope (AFM). The electrical characteristics of Au/$ZrO_2$/Si and Au/BLT/$ZrO_2$/Si film were investigated by C-V and I-V measurements. No hysteretic characteristics was observed in the C-V curve of the Au/$ZrO_2$/Si structure. The memory window width m C-V curve of the Au/BLT/$ZrO_2$/Si diode was about 1.3 V for a voltage sweep of ${\pm}5$ V. The leakage current of Au/$ZrO_2$/Si and Au/BLT/$ZrO_2$/Si structures were about $3{\times}10^{-8}$ A at 30 MV/cm and $3{\times}10^{-8}$ A at 3 MV/cm, respectively.

• 대한치과보철학회지
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• 제39권4호
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• pp.336-350
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• 2001

The purpose of this study was to investigate corrosion tendency and to compare corrosion resistance of three dental magnetic attachments and its keeper alloy by coercive, electrochemical method. By using petentiodynamic polarization technique, magnetic elements and its keeper alloy of Magfit EX600 system(MF, MFK), Dyna ES regular system(DN, DNK) and Shiner SR magnet system(SR, SRK) were corroded electrochemically in 0.9% NaCl electrolytic solution. Open-circuit potential and anodic polarization curve was measured with Potentiostat(model 273 EG&E) and polarization curve was created by current density per square area following scanning of increased series of voltage in the rate of 1.0mV per second. Before and after electrochemical corrosion, the surface roughness test was done. Thereafter the change of mean surface roughness value(Ra) and mean peak value(Rt) of surface roughness was compared one another. In order to observe the corroded surface of each specimen, metallurgical light microscopic(${\times}37.5$) and scanning electron microscopic view(SEM ${\times}100$) was taken and compared one another. Conclusion is followings. 1. All of six covering metal of dental magnetic attachments and its keeper alloy were corroded in various degree after electrochemical corrosion. 2. The corrosion resistance of which used in this experiment is the following in high order; DNK, MFK, DN, MF, SRK and SR. 3. Especially Shiner magnet system and its keeper alloy were more severely corroded after electrochemical corrosion and the change of Ra Rt value were more increased than others. 4 Metallurgical and scanning electron microscopic view showed the pitting corrosion tendency of all experimental alloy but DNK and SR. 5. Covering metal of magnet was more corroded than its keeper alloy.

• 열처리공학회지
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• 제9권1호
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• pp.34-44
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• 1996

Austenite stainless steel was produced by arc welding with current 650A, voltage 50V and welding speed 10cm/min. It was post-welded and then heat treated at $1,050^{\circ}C$ for 120min. And then it was immersed in water or in air. The microstructural changes, ferrite contents, mechanical properties, and stress corrosion cracking(SCC) were investigated. The SCC was studied in 42wt% boiling $MgCl_2$($140^{\circ}C$) under the constant stress using SCC elongation curve. The results showed that; 1. The as-welded spedimen seemed to increase ${\delta}$-ferrite content largely, and revealed continuous network of lathy and vermicular type. The post-welded heat treatment changed the morphologies of ferrite from continuous type to island type. 2. The as-welded, air and water quenched specimens had the ${\delta}$-ferrite content 9.7%, 3.2% and 2.1% respectively. We also showed that ${\delta}$-ferrite was Cr-rich and Ni-poor by EPMA. 3. The time of failure on the SCC was measured and it was used for corrosion elongation curve. The condition of SCC was investigated under $35kgf/mm^2$ load and the results were as follows; 4. The intergranullar cracking by stress corrosion was most distinct in weld metal while the transgranular cracking occurred in the air cooled specimen.

• Smart Structures and Systems
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• 제23권6호
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• pp.565-577
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• 2019

One of the most effective countermeasures for mitigating cable vibration is to install mechanical dampers near the anchorage of the cable. Most of the dampers used in the field are so-called passive dampers where their parameters cannot be changed once designed. The parameters of passive dampers are usually determined based on the optimal damper force obtained from the universal design curve for linear dampers, which will provide a maximum additional damping for the cable. As the optimal damper force is chosen based on a predetermined principal vibration mode, passive dampers will be most effective if cable undergoes single-mode vibration where the vibration mode is the same as the principal mode used in the design. However, in the actual engineering practice, multi-mode vibrations are often observed for cables. Therefore, it is desirable to have dampers that can suppress different modes of cable vibrations simultaneously. In this paper, MR dampers are proposed for controlling multi-mode cable vibrations, because of its ability to change parameters and its adaptability of active control without inquiring large power resources. Although the highly nonlinear feature of the MR material leads to a relatively complex representation of its mathematical model, effective control strategies can still be derived for suppressing multi-mode cable vibrations based on nonlinear modelling, as proposed in this paper. Firstly, the nonlinear Bouc-wen model is employed to accurately portray the salient characteristics of the MR damper. Then, the desired optimal damper force is determined from the universal design curve of friction dampers. Finally, the input voltage (current) of MR damper corresponding to the desired optimal damper force is calculated from the nonlinear Bouc-wen model of the damper using a piecewise linear interpolation scheme. Numerical simulations are carried out to validate the effectiveness of the proposed control algorithm for mitigating multi-mode cable vibrations induced by different external excitations.