• Current Optics and Photonics
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• v.4 no.4
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• pp.368-372
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• 2020

We report the terahertz time-domain spectroscopy (THz-TDS) of transdermal drug delivery in human skin. The time evolution of transdermal nicotine delivery in nicotine patches was assessed by detecting the transmission coefficient of sub-picosecond THz pulses and using a semi-analytic model based on the single-layer effective medium approximation. Using commercial nicotine patches (Nicoderm CQ^®, 7 mg/24 h), THz transmission coefficients were measured to quantitatively analyze the cumulative amounts of nicotine released from the patches in the absence of their detailed specifications, including multilayer structures and optical properties at THz frequencies. The results agreed well with measurements by conventional in vitro and in vivo methods, using a diffusion cell with high-performance liquid chromatography and blood sampling respectively. Our study revealed the ability of the THz-TDS method to be an effective alternative to existing methods for noninvasive and label-free assessments of transdermal drug delivery, showing its high promise for biomedical, pharmaceutical, and cosmetic applications.

• Current Optics and Photonics
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• v.5 no.2
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• pp.101-113
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• 2021

Adaptive optics (AO) systems are becoming more complex to improve their optical performance and enlarge their field of view, so it is a hard and time consuming process to set up and optimize the components of AO systems with actual implementation. However, simulations allow AO scientists and engineers to experiment with different optical layouts and components without needing to obtain and prepare them physically. In this paper, we introduce a new AO simulation named the Korea Adaptive Optics Simulation (KAOS), independently developed by LIG Nex1. We verified the performance of KAOS by comparing with other AO simulation tools. In the comparison simulation, we confirmed the results from KAOS and other AO simulation tools were very similar. Also, we proposed a laser tomography AO system with five Rayleigh laser guide stars (LGSs) optimized by using KAOS to overcome the disadvantages of the AO system with a single sodium LGS for the satellite imaging system. We verified the performance of the proposed AO system using KAOS, and the simulation result showed averaged Strehl ratio of 0.37.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.9
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• pp.3120-3137
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• 2021

Small-sized IoT wireless sensing devices can be deployed with small aircraft such as drones, and the deployment of mobile IoT devices can be relocated to suit data collection with efficient relocation algorithms. However, the terrain may not be able to predict its shape. Mobile IoT devices suitable for these terrains are hopping devices that can move with jumps. So far, most hopping sensor relocation studies have made the unrealistic assumption that all hopping devices know the overall state of the entire network and each device's current state. Recent work has proposed the most realistic distributed network environment-based relocation algorithms that do not require sharing all information simultaneously. However, since the shortest path-based algorithm performs communication and movement requests with terminals, it is not suitable for an area where the distribution of obstacles is uneven. The proposed scheme applies a simple Monte Carlo method based on relay nodes selection random variables that reflect the obstacle distribution's characteristics to choose the best relay node as reinforcement learning, not specific relay nodes. Using the relay node selection random variable could significantly reduce the generation of additional messages that occur to select the shortest path. This paper's additional contribution is that the world's first distributed environment-based relocation protocol is proposed reflecting real-world physical devices' characteristics through the OMNeT++ simulator. We also reconstruct the three days-long disaster environment, and performance evaluation has been performed by applying the proposed protocol to the simulated real-world environment.

• Investigative Magnetic Resonance Imaging
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• v.25 no.2
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• pp.81-92
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• 2021

The role of neuroimaging in patients with acute ischemic stroke has been gradually increasing. The ultimate goal of stroke imaging is to make a streamlined imaging workflow for safe and efficient treatment based on optimized patient selection. In the era of multimodal comprehensive imaging in strokes, imaging based on computed tomography (CT) has been preferred for use in acute ischemic stroke, because, despite the unique strengths of magnetic resonance imaging (MRI), MRI has a longer scan duration than does CT-based imaging. However, recent improvements, such as multicoil technology and novel MRI acceleration techniques, including parallel imaging, simultaneous multi-section imaging, and compressed sensing, highlight the potential of comprehensive MR-based imaging for strokes. In this review, we discuss the role of stroke imaging in acute ischemic stroke management, as well as the strengths and limitations of MR-based imaging. Given these concepts, we review the current MR acceleration techniques that could be applied to stroke imaging and provide an overview of the previous research on each essential sequence: diffusion-weighted imaging, gradient-echo, fluid-attenuated inversion recovery, contrast-enhanced MR angiography, and MR perfusion imaging.

• Current Applied Physics
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• v.18 no.11
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• pp.1255-1260
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• 2018

In this work, a green and simple one-pot route was developed for the synthesis of highly fluorescent aminofunctionalized graphene quantum dots (a-GQDs) via hydrothermal process without any further modification or surface passivation. We synthesized the a-GQDs using glucose as the carbon source and ammonium as a functionalizing agent without the use of a strong acid, oxidant, or other toxic chemical reagent. The as-obtained aGQDs have a uniform size of 3-4 nm, high contents of amino groups, and show a bright green emission with high quantum yield of 32.8%. Furthermore, the a-GQDs show effective fluorescence quenching for $Cu^{2+}$ ions which can serve as effective fluorescent probe for the detection of $Cu^{2+}$. The fluorescent probe using the obtained aGQDs exhibits high sensitivity and selectivity toward $Cu^{2+}$ with the limit of detection as low as 5.6 nM. The mechanism of the $Cu^{2+}$ induced fluorescence quenching of a-GQDs can be attributed to the electron transfer by the formation of metal complex between $Cu^{2+}$ and the amino groups on the surface of a-GQDs. These results suggest great potential for the simple and green synthesis of functionalized GQDs and a practical sensing platform for $Cu^{2+}$ detection in environmental and biological applications.

• Current Optics and Photonics
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• v.5 no.3
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• pp.298-305
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• 2021

Modern distance sensing methods employ various measurement principles, including triangulation, time-of-flight, confocal, interferometric and frequency comb. Among them, the triangulation method, with a laser light source and an image sensor, is widely used in low-cost applications. We developed an omnidirectional two-dimensional (2D) distance sensor based on the triangulation principle for indoor floor mapping applications. The sensor has a range of 150-1500 mm with a relative resolution better than 4% over the range and 1% at 1 meter distance. It rotationally scans a compact one-dimensional (1D) distance sensor, composed of a near infrared (NIR) laser diode, a folding mirror, an imaging lens, and an image detector. We designed the sensor layout and configuration to satisfy the required measurement range and resolution, selecting easily available components in a special effort to reduce cost. We built a prototype and tested it with seven representative indoor wall specimens (white wallpaper, gray wallpaper, black wallpaper, furniture wood, black leather, brown leather, and white plastic) in a typical indoor illuminated condition, 200 lux, on a floor under ceiling mounted fluorescent lamps. We confirmed the proposed sensor provided reliable distance reading of all the specimens over the required measurement range (150-1500 mm) with a measurement resolution of 4% overall and 1% at 1 meter, regardless of illumination conditions.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.4
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• pp.1426-1447
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• 2021

The payoff game between task publishers and users in the mobile crowdsensing environment is a hot topic of research. A optimal payoff selection model based on stochastic evolutionary game is proposed. Firstly, the process of payoff optimization selection is modeled as a task publisher-user stochastic evolutionary game model. Secondly, the low-quality data is identified by the data quality evaluation algorithm, which improves the fitness of perceptual task matching target users, so that task publishers and users can obtain the optimal payoff at the current moment. Finally, by solving the stability strategy and analyzing the stability of the model, the optimal payoff strategy is obtained under different intensity of random interference and different initial state. The simulation results show that, in the aspect of data quality evaluation, compared with BP detection method and SVM detection method, the accuracy of anomaly data detection of the proposed model is improved by 8.1% and 0.5% respectively, and the accuracy of data classification is improved by 59.2% and 32.2% respectively. In the aspect of the optimal payoff strategy selection, it is verified that the proposed model can reasonably select the payoff strategy.

• Current Optics and Photonics
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• v.6 no.3
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• pp.313-322
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• 2022

Remote-sensing optical payloads, especially hyperspectral imagers, have particular issues with stray light because they often encounter high-contrast target/background conditions, such as sun glint. While developing an optical payload, we usually apply several stray-light analysis methods, including forward and backward analyses, separately or in combination, to support lens design and optomechanical design. In addition, we often characterize the stray-light response over a full field to support calibration, or when developing an algorithm to correct stray-light errors. For this purpose, we usually use forward analysis across the entire field, but this requires a tremendous amount of computational time. In this paper, we propose a sequence of forward-backward-forward analyses to more effectively investigate the through-field response of stray light, utilizing the combined advantages of the individual methods. The application is an airborne hyperspectral imager for creating hyperspectral maps from 900 to 1700 nm in a 5-nm-continuous band. With the proposed method, we have investigated the through-field response of stray light to an effective accuracy of 0.1°, while reducing computation time to 1/17^th of that for a conventional, forward-only stray-light analysis.

• Current Optics and Photonics
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• v.5 no.4
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• pp.444-449
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• 2021

A photonic crystal coupled-cavity waveguide created on silicon-on-insulator is designed to act as a refractive-index-sensing device at midinfrared wavelengths around 4 ㎛. To realize high sensitivity, effort is made to engineer the structural parameters to obtain strong modal confinement, which can enhance the interaction between the resonance modes and the analyzed sample. By adjusting some parameters, including the shape of the cavity, the width of the coupling cavity, and the size of the surrounding dielectric columns, a high-sensitivity refractive-index sensor based on the optimized photonic crystal coupled-cavity waveguide is proposed, and a sensitivity of approximately 2620 nm/RIU obtained. When an analyte is measured in the range of 1.0-1.4, the sensor can always maintain a high sensitivity of greater than 2400 nm/RIU. This work demonstrates the viability of high-sensitivity photonic crystal waveguide devices in the midinfrared band.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.453-459
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• 2022

This study attempted to explore the realization and research direction of a successful metaverse environment in the future by analyzing international research trends of the metaverse using topic modeling. A total of 208 papers among WoS and ScienceDirect papers using metaverse as keywords were selected, and quantitative frequency analysis and topic modeling were performed. As a result, it was confirmed that research has rapidly increased after 2022. The main keywords of the research topics were 'second', 'life', 'learning', 'reality', 'metaverse', 'virtual', 'blockchain', 'nft', 'medical', 'avatar', etc. The topic keywords 'Second life & Education' and 'Virtual Reality & Medical' accounted for a large proportion of 57%, followed by 'Blockchain & Cryptocurrency', 'Avatar & Interaction', and 'Sensing and Device'. As a result of semantic analysis, current metaverse research is focused on application and utilization, and research on underlying technologies and devices is also active. Therefore, it is necessary to identify the commonalities and differences between domestic and foreign studies, and to study the application method considering the domestic environment. In addition, new jurisprudence research is more necessary along with predicting new problems. It is expected that the results of study will provide the right research direction for domestic researchers in the era of digital transformation and contribute to the realization of a digital society.