• Clinical Endoscopy
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• v.55 no.6
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• pp.801-809
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• 2022

Background/Aims: Current society guidelines recommend antibiotic prophylaxis for 3 to 5 days after endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of pancreatic cystic lesions (PCLs). The overall quality of the evidence supporting this recommendation is low. In this study, we aimed to assess cyst infection and adverse event rates after EUS-FNA of PCLs among patients treated with or without postprocedural prophylactic antibiotics. Methods: We retrospectively reviewed all patients who underwent EUS-FNA of PCLs between 2015 and 2019 at two large-volume academic medical centers with different practice patterns of postprocedural antibiotic prophylaxis. Data on patient demographics, cyst characteristics, fine-needle aspiration technique, periprocedural and postprocedural antibiotic prophylaxis, and adverse events were retrospectively extracted. Results: A total of 470 EUS-FNA procedures were performed by experienced endosonographers for the evaluation of PCLs in 448 patients, 58.7% of whom were women. The mean age was 66.3±12.8 years. The mean cyst size was 25.7±16.9 mm. Postprocedural antibiotics were administered in 274 cases (POSTAB+ group, 58.3%) but not in 196 cases (POSTAB- group, 41.7%). None of the patients in either group developed systemic or localized infection within the 30-day follow-up period. Procedure-related adverse events included mild abdominal pain (8 patients), intra-abdominal hematoma (1 patient), mild pancreatitis (1 patient), and perforation (1 patient). One additional case of pancreatitis was recorded; however, the patient also underwent endoscopic retrograde cholangiopancreatography. Conclusions: The incidence of infection after EUS-FNA of PCLs is negligible. Routine use of postprocedural antibiotics does not add a significant benefit.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.2
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• pp.113-118
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• 2012

Ginsenosides are low molecular weight glycosides found in ginseng that exhibit neuroprotective effects through inhibition of $N$-methyl-D-aspartic acid (NMDA) receptor channel activity. Ginsenosides, like other natural compounds, are metabolized by gastric juices and intestinal microorganisms to produce ginsenoside metabolites. However, little is known about how ginsenoside metabolites regulate NMDA receptor channel activity. In the present study, we investigated the effects of ginsenoside metabolites, such as compound K (CK), protopanaxadiol (PPD), and protopanaxatriol (PPT), on oocytes that heterologously express the rat NMDA receptor. NMDA receptor-mediated ion current ($I_{NMDA}$) was measured using the 2-electrode voltage clamp technique. In oocytes injected with cRNAs encoding NMDA receptor subunits, PPT, but not CK or PPD, reversibly inhibited $I_{NMDA}$ in a concentration-dependent manner. The $IC_{50}$ for PPT on $I_{NMDA}$ was $48.1{\pm}4.6\;{\mu}M$, was non-competitive with NMDA, and was independent of the membrane holding potential. These results demonstrate the possibility that PPT interacts with the NMDA receptor, although not at the NMDA binding site, and that the inhibitory effects of PPT on $I_{NMDA}$ could be related to ginseng-mediated neuroprotection.

• Journal of Broadcast Engineering
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• v.13 no.6
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• pp.883-891
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• 2008

Multiple antenna orthogonal frequency division multiplexing (OFDM) is a promising technique for the high downlink-capacity in the next generation wireless systems, in which adaptive resource allocation is an important research issue that can significantly improve the performance with guaranteed QoS for users. However, most of the current resource allocation algorithms are limited to unicast system. In this paper, dynamic resource allocation is studied for multiple antenna OFDM based systems with multicast service. In the simulation, the performance of multicast system was compared with that of the unicast system. Numerical results also show that by using the proposed algorithms the system capacity is significantly improved compared with the conventional scheme.

• Korean Journal of Applied Biomechanics
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• v.21 no.5
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• pp.503-510
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• 2011

The purpose of this study was to find the biomechanical research project result carried out at 2011 IAAF World championship in Daegu. This project was approved by the International Amateur Athletic Federation(IAAF) and financially supported by the Ministry of Culture, Sports and Tourism(MCST) and, Korea Association of Athletics Federations(KAAF). The total number of the project members was 20, including the members of the Scientific Committee, the Korean Society of Sport Biomechanics(KSSB) and graduate students as assistants. The objective of this project has been to analyze the performance in the track events(100 m, 110 mH) and field events(Long Jump, High Jump, Triple Jump, Pole Vault, Javelin Throw and Shot Put). This project was focused on the biomechanical research only. This kind of analysis has been carried out at major competitions for more than a decade, as it provides coaches and athletes with very useful information as an aid to training programmes and competition preparation. The biomechanical analysis of the top athletes in the world in each specialty serves as a reference for assessing technique and rationalizing the results achieved. The results will be disseminated world-wide and coaches will be in a better position to design training strategies in line with current world trends.

• Journal of Animal Science and Technology
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• v.48 no.2
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• pp.169-190
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• 2006

Researches in livestock are currently actively progressing to improve economically important traits using DNA markers. In cattle, the candidate genes have been selected based on their known functions in the target QTL (quantitative trait locus) region in order to identify QTN (quantitative trait nucleotide) for improving productivities. In this review, molecular genetic studies for the meat related traits, one of the major determinant of market prices, have been fully described. Also recent emerging microarray technique for identifying candidate genes in cattle has been discussed. In case of microarray, cDNA microarrays have been replaced to oligoarrays in order to minimize the experimental errors in cattle. Since the first draft of bovine genome sequences was appeared in the public domain, more markers in relation to the quantitative traits will be discovered in a short period of time and genes affecting difficult-to-measure traits, such as disease resistance, can also be selected for marker assisted selection in near future.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.6
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• pp.1479-1495
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• 2012

Spectrum scarcity seems to be the most challenging issue to be solved in new wireless telecommunication services. It is shown that spectrum unavailability is mainly due to spectrum inefficient utilization and inappropriate physical layer execution rather than spectrum shortage. Daily increasing demand for new wireless services with higher data rate and QoS level makes the upgrade of the physical layer modulation techniques inevitable. Orthogonal Frequency Division Multiple Access (OFDMA) which utilizes multicarrier modulation to provide higher data rates with the capability of flexible resource allocation, although has widely been used in current wireless systems and standards, seems not to be the best candidate for cognitive radio systems. Filter Bank based Multi-Carrier (FBMC) is an evolutionary scheme with some advantages over the widely-used OFDM multicarrier technique. In this paper, we focus on the total throughput improvement of a cognitive radio network using FBMC modulation. Along with this modulation scheme, we propose a novel uplink radio resource allocation algorithm in which fairness issue is also considered. Moreover, the average throughput of the proposed FBMC based cognitive radio is compared to a conventional OFDM system in order to illustrate the efficiency of using FBMC in future cognitive radio systems. Simulation results show that in comparison with the state of the art two algorithms (namely, Shaat and Wang) our proposed algorithm achieves higher throughputs and a better fairness for cognitive radio applications.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.43 no.4 s.310
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• pp.27-36
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• 2006

Lossless data embedding is a method to insert information into a host image that guarantees complete restoration when the extraction has been done. In this paper, we propose a noble reversible data embedding algorithm for images in wavelet domain. The proposed embedding technique, which modifies histogram of wavelet coefficient, is composed of two inserting steps. Data is embedded to wavelet coefficient using modification of histogram in first embedding process. Second embedding step compensates the distortion caused by the first embedding process as well as hides more information. Hence we achieve higher inserting capacity. In view of the relationship between the embedding capacity and the PSNR value, our proposed method shows considerably higher performance than the current reversible data embedding methods.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.38 no.3
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• pp.100-107
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• 2015

Recently as the manufacturers want competitiveness in dynamically changing environment, they are trying a lot of efforts to be efficient with their production systems, which may be achieved by diminishing unplanned operation stops. The operation stops and maintenance cost are known to be significantly decreased by adopting proper maintenance strategy. Therefore, the manufacturers were more getting interested in scheduling of exact maintenance scheduling to keep smooth operation and prevent unexpected stops. In this paper, we proposedan integrated maintenance approach in injection molding manufacturing line. It consists of predictive and preventive maintenance approach. The predictive maintenance uses the statistical process control technique with the real-time data and the preventive maintenance is based on the checking period of machine components or equipment. For the predictive maintenance approach, firstly, we identified components or equipment that are required maintenance, and then machine parameters that are related with the identified components or equipment. Second, we performed regression analysis to select the machine parameters that affect the quality of the manufactured products and are significant to the quality of the products. By this analysis, we can exclude the insignificant parameters from monitoring parameters and focus on the significant parameters. Third, we developed the statistical prediction models for the selected machine parameters. Current models include regression, exponential smoothing and so on. We used these models to decide abnormal patternand to schedule maintenance. Finally, for other components or equipment which is not covered by predictive approach, we adoptedpreventive maintenance approach. To show feasibility we developed an integrated maintenance support system in LabView Watchdog Agent and SQL Server environment and validated our proposed methodology with experimental data.

• Journal of Surface Science and Engineering
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• v.49 no.1
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• pp.40-45
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• 2016

Recently, $Bi_2Te_3$-based alloys are the best thermoelectric materials near to room temperature, so it has been researched to achieve increased figure of merit(ZT). Ternary compounds such as Bi-Te-Se and Bi-Sb-Te have higher thermoelectric property than binary compound Bi-Te and Sb-Te, respectively. Compared to DC plating method, pulsed electrodeposition is able to control parameters including average current density, and on/off pulse time etc. Thereby the morphology and properties of the films can be improved. In this study, we electrodeposited n-type ternary Cu-doped $Bi_2(Te-Se)_3$ thin film by modified pulse technique at room temperature. To further enhance thermoelectric properties of $Bi_2(Te-Se)_3$ thin film, we optimized Cu doping concentration in $Bi_2(Te-Se)_3$ thin film and correlated it to electrical and thermoelectric properties. Thus, the crystal, electrical, and thermoelectric properties of electrodeposited $Bi_2(Te-Se)_3$ thin film were characterized the XRD, SEM, EDS, Seebeck measurement, and Hall effect measurement, respectively. As a result, the thermoelectric properties of Cu-doped $Bi_2(Te-Se)_3$ thin films were observed that the Seebeck coefficient is $-101.2{\mu}V/K$ and the power factor is $1412.6{\mu}W/mK^2$ at 10 mg of Cu weight. The power factor of Cu-doped $Bi_2(Te-Se)_3$ thin film is 1.4 times higher than undoped $Bi_2(Te-Se)_3$ thin film.

• Journal of Plant Biotechnology
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• v.37 no.4
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• pp.408-413
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• 2010

The paper reviewed research status and outlook of genetic transformation in fruit trees in Korea. Genetic transformation has been long considered as an alternative technique overcoming limitation of conventional breeding and conducted since early 1990's. An efficient genetic transformation was established with major cultivars of apple, even in Fuji and Gamhong, and some transgenic apple plants have been transferred into the greenhouse for further analysis of gene expression. A few successes of genetic transformation have been reported and application to a variety of cultivars tried in citrus and kiwifruit. Successful genetic transformation has not been reported in the other fruit trees including grapevine, yet and it is considered being at the level of research. Those factors including replacement of antibiotics as a selective agent, use of transgenic rootstocks and manipulation of gene expression at proper parts and developmental stages have been prerequisites for the rapid commercialization of transgenic fruit plants.