• Title/Summary/Keyword: current division technique

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Proteomics in Rheumatoid Arthritis Research

  • Park, Yune-Jung;Chung, Min Kyung;Hwang, Daehee;Kim, Wan-Uk
    • IMMUNE NETWORK
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    • v.15 no.4
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    • pp.177-185
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    • 2015
  • Although rheumatoid arthritis (RA) is the most common chronic inflammatory autoimmune disease, diagnosis of RA is currently based on clinical manifestations, and there is no simple, practical assessment tool in the clinical field to assess disease activity and severity. Recently, there has been increasing interest in the discovery of new diagnostic RA biomarkers that can assist in evaluating disease activity, severity, and treatment response. Proteomics, the large-scale study of the proteome, has emerged as a powerful technique for protein identification and characterization. For the past 10 years, proteomic techniques have been applied to different biological samples (synovial tissue/fluid, blood, and urine) from RA patients and experimental animal models. In this review, we summarize the current state of the application of proteomics in RA and its importance in identifying biomarkers and treatment targets.

Effect of Photosensitive Carbon Nanotube Paste on Field Emission Properties (감광성 탄소나노튜브 페이스트의 조성과 열처리가 전계방출 특성에 미치는 영향)

  • Oh, Jeong-Seob;Kim, Dae-Jun;Jeong, Jin-Woo;Song, Yoon-Ho;Cho, Young-Rae
    • Korean Journal of Materials Research
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    • v.16 no.9
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    • pp.550-556
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    • 2006
  • Photosensitive carbon nanotube (CNT) pastes are explored to develop a CNT field emitter for field emission display (FED) application. We formulated a photosensitive paste including multi-walled CNTs (MWNTs) for screen printing. The photosensitive CNT paste was synthesized by mixing of MWNTs, inorganic fillers (nano metal), organic vehicle, monomers and photo initiator. The CNT paste films were patterned by using backside exposure technique. The CNTs were strongly fixed on a cathode by formation of carbon residue during firing process. For the CNT emitters, current-voltage(I-V) characteristics and images of field emission were evaluated. The emission properties of CNT emitters are dependent on the paste composition. A turn-on electric field for the CNT field emitters is measured to be 1 V/$\mu$m. Additionally, the effect of heat treatment parameter on field emission properties was discussed. The newly formulated photosensitive CNT paste can be potentially applicable to highly reliable CNT field emitters.

Analysis of Radiation Characteristics of the Shaped Cassegrainian Antenna (수정곡면 카세그레인 안테나의 복사특성 해석)

  • Ryu, Hwang;Joo, Gi-Ho
    • The Journal of Engineering Research
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    • v.3 no.1
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    • pp.159-169
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    • 1998
  • The purpose of this study is to analyze the radiation characteristics of the shaped Cassegrainian antenna. Radiation pattern of the sub-reflector is calculated by GTD (Geometrical Theory of Diffraction) The complete radiation patterns are obtained by summing the reflect field from the surface and the diffracted fields from the edge. The first and the second derivative on the sub-reflector are calculated by the local interpolation technique. The Radiation characteristics of the main-reflector are obtained by integrating the surface current density, which is derived from PO approximation. The radiation integral is expanded by the Jacobi-Bessel series for the purpose of reducing the computation time.

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Thickness dependence of grain growth orientation in MgB2 films fabricated by hybrid physical-chemical vapor deposition

  • Ranot, Mahipal;Kang, W.N.
    • Progress in Superconductivity and Cryogenics
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    • v.15 no.2
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    • pp.9-11
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    • 2013
  • We have investigated the effect of thickness of the MgB2 film on the grain growth direction as well as on their superconducting properties. $MgB_2$ films of various thicknesses were fabricated on c-cut $Al_2O_3$ substrates at a temperature of $540^{\circ}C$ by using hybrid physical-chemical vapor deposition (HPCVD) technique. The superconducting transition temperature ($T_c$) was found to increase with increase in the thickness of the $MgB_2$ film. X-ray diffraction analysis revealed that the orientation of grains changed from c-axis to a-axis upon increasing the thickness of the $MgB_2$ film from 0.6 to 2.0 ${\mu}m$. $MgB_2$ grains of various orientations were observed in the microstructures of the films examined by scanning electron microscopy. It is observed that at high magnetic fields the 2.0-${\mu}m$-thick film exhibit considerably larger critical current density ($J_c$) as compared to 0.6-${\mu}m$-thick film. The results are discussed in terms of an intrinsic-pinning in $MgB_2$ similarly as intrinsic-pinning occurring in high-Tc cuprate superconductors with layered structure.

10-GHz band 2 × 2 phased-array radio frequency receiver with 8-bit linear phase control and 15-dB gain control range using 65-nm complementary metal-oxide-semiconductor technology

  • Seon-Ho Han;Bon-Tae Koo
    • ETRI Journal
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    • v.46 no.4
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    • pp.708-715
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    • 2024
  • We propose a 10-GHz 2 × 2 phased-array radio frequency (RF) receiver with an 8-bit linear phase and 15-dB gain control range using 65-nm complementary metal-oxide-semiconductor technology. An 8 × 8 phased-array receiver module is implemented using 16 2 × 2 RF phased-array integrated circuits. The receiver chip has four single-to-differential low-noise amplifier and gain-controlled phase-shifter (GCPS) channels, four channel combiners, and a 50-Ω driver. Using a novel complementary bias technique in a phase-shifting core circuit and an equivalent resistance-controlled resistor-inductor-capacitor load, the GCPS based on vector-sum structure increases the phase resolution with weighting-factor controllability, enabling the vector-sum phase-shifting circuit to require a low current and small area due to its small 1.2-V supply. The 2 × 2 phased-array RF receiver chip has a power gain of 21 dB per channel and a 5.7-dB maximum single-channel noise-figure gain. The chip shows 8-bit phase states with a 2.39° root mean-square (RMS) phase error and a 0.4-dB RMS gain error with a 15-dB gain control range for a 2.5° RMS phase error over the 10 to10.5-GHz band.

Invasive strategies for rhythm control of atrial fibrillation: a narrative review

  • Hong-Ju Kim;Chan-Hee Lee
    • Journal of Yeungnam Medical Science
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    • v.41 no.4
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    • pp.279-287
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    • 2024
  • Atrial fibrillation (AF) is the most common sustained tachyarrhythmia and its increasing prevalence has resulted in a growing health-care burden. A recent landmark randomized trial, the EAST-AFNET 4 (Early Treatment of Atrial Fibrillation for Stroke Prevention Trial), highlighted the importance of early rhythm control in AF, which was previously underemphasized. Rhythm control therapy includes antiarrhythmic drugs, direct-current cardioversion, and catheter ablation. Currently, catheter ablation is indicated for patients with AF who are either refractory or intolerant to antiarrhythmic drugs or who exhibit decreased left ventricular systolic function. Catheter ablation can be categorized according to the energy source used, including radiofrequency ablation (RFA), cryoablation, laser ablation, and the recently emerging pulsed field ablation (PFA). Catheter ablation techniques can also be divided into the point-by-point ablation method, which ablates the pulmonary vein (PV) antrum one point at a time, and the single-shot technique, which uses a spherical catheter to ablate the PV antrum in a single application. PFA is known to be applicable to both point-by-point and single-shot techniques and is expected to be promising owing to its tissue specificity, resulting in less collateral damage than catheter ablation involving thermal energy, such as RFA and cryoablation. In this review, we aimed to outline catheter ablation for rhythm control in AF by reviewing previous studies.

A new sensorless speed control method for permanent magnet synchronous motor using direct torque control (직접토크제어를 이용한 영구자석 동기전동기의 새로운 센서리스 속도제어)

  • Oh, Sae-Gin;Kim, Jong-Su;Kim, Sung-Hwan
    • Journal of Advanced Marine Engineering and Technology
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    • v.37 no.6
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    • pp.653-658
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    • 2013
  • This paper describes a new sensorless speed control method for permanent magnet synchronous motor(PMSM) using direct torque control(DTC). The direct torque control offers fast torque response, lesser hardware and processing costs as compared to vector controlled drives. In this paper the current error compensation technique is applied for sensorless speed control of synchronous motor. Through this method, the controlled stator voltage is applied to the synchronous motor so that the error between stator currents of the mathematical model and the actual motor can be forced to decay to zero as time proceeds and therefore, the motor speed approaches to the setting value. Especially, any PI controllers are not necessary in this control method. The simulation results indicate good speed and load responses from the low speed range to the high.

A Study on the Method of Ecosystem Health Assessment in National Parks (국립공원 생태계 건강성 평가 방법에 관한 연구)

  • Oh, Jang Geun;Won, Hyeok Jae;Myeong, Hyeon-Ho
    • Korean Journal of Ecology and Environment
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    • v.49 no.2
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    • pp.147-152
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    • 2016
  • This study was conducted to develop a technique of ecosystem health assessment on Korea National Parks. The purpose of natural resource monitoring in national parks is to develop scientific information on the current status and long term trends in the composition, structure, and function of park ecosystems, and to determine how well current management practices are sustaining those ecosystems. The evaluation results will reflect in the park conservation and polices and promote the effect and functions of assessment program to the people. Health assessment steps were performed in order the establishing monitoring goals and objectives, development of the conceptual model, frame establishment, determination of indicators, standard and classification and health assessment. Health Indicators were selected the 13 with common, choice and climate indicators. We developed a pictogram and was separated into five colors to health condition, it was divided into three shape for comparison with the past state. Seoraksan, Odaesan National Park has been rated highly but Bukhansan, Kyeryongsan National Park has been underestimated.

Distribution of Cd and Pb Accumulated in Medicinal Plant Roots and Their Cultivation Soils

  • Seo, Byoung-Hwan;Kim, Hyuck Soo;Bae, Jun-Sik;Kim, Won-Il;Hong, Chang-Ho;Kim, Kwon-Rae
    • Korean Journal of Soil Science and Fertilizer
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    • v.48 no.4
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    • pp.278-284
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    • 2015
  • In general, plant roots accumulate more heavy metals than the above ground organs such as leaf, stem, and fruit. This implies that root medicinal plants would be an issue with excessive heavy metal accumulation. Therefore, the current study was carried out to investigate the distribution of heavy metal (focused on Cd and Pb) concentrations in soils and medicinal plant roots grown in different region of Korea. Total 293 samples for each soil and plant were collected along the national wide. Soil pH, total and phytoavailable metal concentrations (1 M $NH_4NO_3$ extracted) in soils were determined and heavy metal concentrations in root of the medicinal plants were analyzed. Heavy metal concentrations of the soil samples studied were not exceeded standard limits legislated in 'Soil Environmental Conservation Act', except 2 samples for Cu. However, substantial amount of Cd was accumulated in medicinal plant roots with 29% samples exceeding the standard limit legislated in 'Pharmaceutical Affairs Act' while all plant samples were lower than the standard limit value for Pb. Also the current study demonstrated that cadmium concentrations in the roots were governed by the phytoavailable Cd in soils, which decreased as soil pH increased. From this result, application of heavy metal immobilization technique using a pH change-induced immobilizing agents can be suggested for safer root medicinal plant production.

Checkmeat: A Review on the Applicability of Conventional Meat Authentication Techniques to Cultured Meat

  • Ermie Jr. Mariano;Da Young Lee;Seung Hyeon Yun;Juhyun Lee;Seung Yun Lee;Sun Jin Hur
    • Food Science of Animal Resources
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    • v.43 no.6
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    • pp.1055-1066
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    • 2023
  • The cultured meat industry is continuously evolving due to the collective efforts of cultured meat companies and academics worldwide. Though still technologically limited, recent reports of regulatory approvals for cultured meat companies have initiated the standards-based approach towards cultured meat production. Incidents of deception in the meat industry call for fool-proof authentication methods to ensure consumer safety, product quality, and traceability. The cultured meat industry is not exempt from the threats of food fraud. Meat authentication techniques based on DNA, protein, and metabolite fingerprints of animal meat species needs to be evaluated for their applicability to cultured meat. Technique-based categorization of cultured meat products could ease the identification of appropriate authentication methods. The combination of methods with high sensitivity and specificity is key to increasing the accuracy and precision of meat authentication. The identification of markers (both physical and biochemical) to differentiate conventional meat from cultured meat needs to be established to ensure overall product traceability. The current review briefly discusses some areas in the cultured meat industry that are vulnerable to food fraud. Specifically, it targets the current meat and meat product authentication tests to emphasize the need for ensuring the traceability of cultured meat.