• Maxillofacial Plastic and Reconstructive Surgery
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• v.32 no.1
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• pp.23-26
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• 2010

The vascular changes in periodontal tissues cause local hypoxia which seems to affect the periodontal tissue cells. Abrupt changes in oxygen availability within the periodontium have been suggested to have a regulatory role in alveolar bone remodeling during tooth movement, bone growth or fracture healing. The purpose of this study was to study the effects of hypoxia on formation of osteoclast responsible for bone resorption, in vitro. Primary mouse bone marrow cells were cultured in normoxic (20% $O_2$) and hypoxic (1% $O_2$) conditions and assayed for cellular proliferation. The results obtained were as follows : 1. Reducing oxygen tension increased the formation of multinucleated osteoclasts. 2. Hypoxic stimulus increased the size of mature osteoclasts.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.5
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• pp.1065-1071
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• 2007

It has been known that Asian Medicine theory are based on yin and yang & Five Phases. but recently many therapist using asian medicine in Korea or another nations, take up the position that it is not inevitable for them to adopt the theory of yin-and-yang & Five Phases when they cure a patient. but the point of this view suggests they can not understand totally the real theory about yin-and-yang & Five Phases. asian image-mathematics based on I-Ching could analysis all things with the natural number. the kernel of understanding on principle of I-Ching is realizing that the standard should be changed in some conditions and the form of cosmos should change endless. the system of all thing under sun is divided in three parts on the asian image-mathematics. the nature number from one to nine is divided in three categories that are grouped as 123, 456, 789. So, if we want to understand Five Phases theory, we suggest that it is useful to know the organic connected relations among Four Images, Five Phases, Six Qi(six kinds of weather). the aim of this paper is to arrive at understanding of profound learning on image-mathematics throughout the number of 4, 5, 6 in the concrete context.

• Journal of the Korean Society of Clothing and Textiles
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• v.13 no.1 s.29
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• pp.59-66
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• 1989

This paper is concerned with formaldehyde release from durable press finished rayon fabrics. $100\%$ rayon fabrics were treated with 3 kinds of commercial N-methylol crosslinking agents using a pad-dry cure technique. Aqueous extractions of fabric samples were carried out at $40^{\circ}C$ under pH's of 4, 7, 10. Formaldehyde release was evaluated for the types of resins, catalyst concentrations and extraction conditions. Results indicated that the higher concentration of catalyst leads to the more fixation of resin on the fabric. Total formaldehyde released to the extract was decreased as the catalyst concentration increased. For the resin types, the amount of formaldehyde released was in the order of DMU>MDMDHEU>DMDHEU. Free formaldehyde content in the extract was in the order of pH10>pH4>pH7. This result proved that resins are least resistant to alkaline hydrolysis and the N-C bond cleavage under alkaline condition. Under acidic condition, however, N-methylol formaldehyde was accumulated before the release of free formaldehyde. This suggested the C·0 bond cleavalge to form carbonium - immonim intermediate.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.1
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• pp.27-38
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• 2020

Alzheimer's disease (AD) is one of the challenging conditions that have no cure, yet early diagnosis can help to control the disease. PET imaging of tau has several advantages, such as being a noninvasive, safe diagnostic technique that correlates directly with the disease progression. Many tau tracers have been reported to date; however, the chemical scaffolds of them fall in a narrow chemical window, and none was approved yet as none is entirely selective and sensitive to tau. These problems are being solved as new tracers emerge constantly. In this report, the first-generation tau tracers such as [¹¹C]PBB3, 2-arylquinoline (THK) series, [¹⁸F]T808, and [¹⁸F]AV-1451 ([¹⁸F]T807) are reviewed from an organic and radiochemistry perspective; thus the most effective chemical approach to synthesize these tracers is discussed. This would help to design novel tracers which can meet the challenges faced by the current tracers.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2000.11a
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• pp.21-29
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• 2000

The Purpose of this paper is to determine the effect of the autoclave inner pressure rate, heat-up rate, tool round angle, Thickness of core, height of joggle on defects, and to minimize the defects of aircraft sandwich structure reinforced with honeycomb core occurred in autoclave processing. The results showed that the geometry of aircraft sandwich structure and tool such as tool round angle, Thickness of core, height of joggle, and the autoclave cure conditions such as inner pressure rate, heat up rate strongly affected the core movement, core wrinkle, bridge phenomenon of prepreg and depression of core that occurred in autoclave processing.

• Textile Coloration and Finishing
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• v.30 no.1
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• pp.29-37
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• 2018

Cotton has no adsorption ability for the cationic dye and heavy metal but, if anionized cotton can be made, it will be possible. In this study, to enable the anionisation of cotton fabric, it was modified using sodium vinylsolfonate(SV) as the anionisation reagent, employing a pad-dry-cure(PDC) technique. The effects of curing time, treatment concentrations of urea, sodium hydroxide and SV on the weight increase were experimented and then, the physical characterizations of sulfoethyl cotton(SEC) depending on the finishing conditions were estimated, thus the application possibility of SV as anionisation reagent was investigated. It was not much changed by anionisation except wrinkle recovery. And the structure of SEC was elucidated by Raman and NMR spectoscopy. The feasibility of using Raman and NMR spectroscopy with the band at $1,043cm^{-1}$, and 50.5ppm, respectively as marker band to determine sulfoethyl group of SEC was reported. The total degree of SV substitution(DSV) was determined via elemental analysis. SEC with diverse total DSV up to 0.066 was obtained. In the thermal decomposition(pyrolysis) by DSC, it can be found that the pyrolysis temperature was about $30^{\circ}C$ lower than that of non-treated cotton fabric.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.7
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• pp.703-713
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• 2012

This study analyzed the physical properties and flame retardancy of Tencel FR/Cotton complex knit fabrics in order to satisfy two aspects of eco-friendliness and functionality. The flame retardant (FR) treatment of complex knit fabrics was applied by a pad-dry-cure method for additional functionality. Tensile strength, extension, bursting strength, LOI, and flame retardancy were measured by the KS (Korean Standard) K manual. The hand value knit fabrics were measured by KES-FB system. Subsequently, tensile strength and extension of wale and tensile strength of course increased in tandem with the Tencel FR yarn content. Tencel FR/Cotton complex knit fabrics were suitable for summer-weight and for baby clothes through the KES-FB system measurements. The bursting strength of Tencel FR/Cotton complex knit fabrics decreased as the contents of the Tencel FR increased; in addition, LOI increased as the contents of Tencel FR increased. This was due to the Tencel FR flame resistance function; however, the tensile strength decreased. The optimum fiber content of Tencel FR/cotton content was 1:1. The optimum conditions of flame retardant treatment were a treatment temperature $130^{\circ}C$ and the concentration of finishing agent and assistance binder (AR4260) was 35% and 1%, respectively.

• Korean Journal of Oriental Medicine
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• v.15 no.3
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• pp.19-28
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• 2009

Objectives : The lawsuits associated with medical practice in Korean medicine are increasing gradually. However, the clear definition for medical practice in Korean medicine has not been existed in Korean law. Only we may understand the concept regulated by judicial precedents of the court of justice or the authoritative interpretation by the government. Methods : For study, a database was established for medical lawsuits involving Korean medicine(1968~2009, n=130). Results : According to court rulings, the medical practice in Korean medicine is an act to diagnose a person's illness, prescribe and treat to cure based on traditional Korean medicine, to be understood as a medical care, to have some factor to create or increase danger for the preservation of health or hygiene, and to be practiced by medical specialists based on their professional knowledge. Conclusions : But, such definition is not proper and exceedingly vague. Besides medical circumstances Koreans Medicine are changing, and new precedent to the definition of the practice of medicine is establishing. Therefore the meaning and scope of the medical practice in Korean medicine should be modified and amended, reflecting these conditions.

• The Journal of Internal Korean Medicine
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• v.18 no.2
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• pp.112-130
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• 1997

This study has been carried out to investigate the cause, pathological mechanism and treatment of stroke in Oidaibiyo(外臺秘要), written by Wangdo(王燾). The results were follows : 1. Oidaibiyo(外臺秘要), which is written by Wangdo gives an account of the symptomatic degree of intensity and diachronic procedure in the chapter of stroke. 2. The cause of stroke is quoted mainly from External Wind(外來風邪), and the hyper-sexual intercourse, hyperalimentation, hyper -consciousness, excessive lavour and so forth as additional. And personal character and external effect, like the climate conditions are also much affected the outbreak of stroke. 3 With respect to the diagnosis of stroke, pulse means here quoted from its conception in Chungumyobang(千金要方) Jebungwonhuron(諸病源候論), and pulse plays an important role in diagnosis of stroke. 4. The treatment for stroke generally attaches much importance to medicine therapy. The concrete cure, BalhanGeopungbub(發汗祛風法) has been mainly available, and the usage of Cheongyulyak(淸熱樂) has been increased, contray to formal.

• Journal of Yeungnam Medical Science
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• v.36 no.2
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• pp.67-77
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• 2019

The paradigm of chronic liver diseases has been shifting. Although hepatitis B and C viral infections are still the main causes of liver cirrhosis and hepatocellular carcinoma (HCC), the introduction of effective antiviral drugs may control or cure them in the near future. In contrast, the burden of nonalcoholic fatty liver disease (NAFLD) has been increasing for decades, and 25 to 30% of the general population in Korea is estimated to have NAFLD. Over 10% of NAFLD patients may have nonalcoholic steatohepatitis (NASH), a severe form of NAFLD. NASH can progress to cirrhosis and HCC. NASH is currently the second leading cause to be placed on the liver transplantation list in the United States. NAFLD is associated with obesity, type 2 diabetes, dyslipidemia, and metabolic syndrome. The pathophysiology is complex and associated with lipotoxicity, inflammatory cytokines, apoptosis, and insulin resistance. The only proven effective treatment is weight reduction by diet and exercise. However, this may not be effective for advanced fibrosis or cirrhosis. Therefore, effective drugs are urgently needed for treating these conditions. Unfortunately, no drugs have been approved for the treatment of NASH. Many pharmaceutical companies are trying to develop new drugs for the treatment of NASH. Some of them are in phase 2 or 3 clinical trials. Here, pharmacologic therapies in clinical trials, as well as the basic principles of drug therapy, will be reviewed, focusing on pathophysiology.