• Asian-Australasian Journal of Animal Sciences
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• v.30 no.11
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• pp.1620-1632
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• 2017

Objective: This study evaluated the effects of a traditional Chinese medicine formula (TCMF) on muscle fiber characteristics in finishing pigs and the effects of the formula's extract (distilled water, ethyl acetate and petroleum ether extraction) on porcine cell proliferation and isoforms of myosin heavy chain (MyHC) gene expression in myocytes. Methods: In a completely randomized design, ninety pigs were assigned to three diets with five replications per treatment and six pigs per pen. The diets included the basal diet (control group), TCMF1 (basal diet+2.5 g/kg TCMF) and TCMF2 (basal diet+5 g/kg TCMF). The psoas major muscle was obtained from pigs at the end of the experiment. Muscle fiber characteristics in the psoas major muscle were analyzed using myosin ATPase staining. Cell proliferation was measured using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) dye and cytometry. Isoforms of MyHC gene expression were detected by real-time quantitative polymerase chain reaction. Results: The final body weight and carcass weight of finishing pigs were increased by TCMF1 (p<0.05), while the psoas major muscle cross-sectional area was increased by TCMF (p<0.05). The cross-sectional area and diameter of psoas major muscle fiber Ι, IIA, and IIB were increased by TCMF2 (p<0.05). The cross-sectional area and fiber diameter of psoas major muscle fiber IIA and IIB were increased by diet supplementation with TCMF1 (p<0.05). Psoas major muscle fiber IIA and IIB fiber density from the pigs fed the TCMF1 diet and the type IIB fiber density from the pigs fed the TCMF2 diet were lower compared to pigs fed the control diet (p<0.05). Pigs fed TCMF2 had a higher composition of type Ι fiber and a lower percentage of type IIB fiber in the psoas major muscle (p<0.05). The expression levels of MyHC Ι, MyHC IIa, and MyHC IIx mRNA increased and the amount of MyHC IIb mRNA decreased in the psoas major muscle from TCMF2, whereas MyHC Ι and MyHC IIx mRNA increased in the psoas major muscle from TCMF1 (p<0.05). Peroxisome proliferator-activated receptor ${\gamma}$ $coactivator-1{\alpha}$ and CaN mRNA expression in the psoas major muscle were up-regulated by TCMF (p<0.05). Porcine skeletal muscle satellite cell proliferation was promoted by $4{\mu}g/mL$ and $20{\mu}g/mL$ TCMF water extraction (p<0.05). Both $1{\mu}g/mL$ and $5{\mu}g/mL$ of TCMF water extraction increased MyHC IIa, MyHC IIb, and MyHC IIx mRNA expression in porcine myocytes (p<0.05), while MyHC Ι mRNA expression in porcine myocytes was decreased by $5{\mu}g/mL$ TCMF water extraction (p<0.05). Porcine myocyte MyHC Ι and MyHC IIx mRNA expression were increased, and MyHC IIa and MyHC IIb mRNA expression were down-regulated by $5{\mu}g/mL$ TCMF ethyl acetate extraction (p<0.05). MyHC Ι and MyHC IIa mRNA expression in porcine myocytes were increased, and the MyHC IIb mRNA expression was decreased by $1{\mu}g/mL$ TCMF ethyl acetate extraction (p<0.05). Four isoforms of MyHC mRNA expression in porcine myocytes were reduced by $5{\mu}g/mL$ TCMF petroleum ether extraction (p<0.05). MyHC IIa mRNA expression in porcine myocytes increased and MyHC IIb mRNA expression decreased by $1{\mu}g/mL$ in a TCMF petroleum ether extraction (p<0.05). Conclusion: These results indicated that TCMF amplified the psoas major muscle cross-sectional area through changing muscle fiber characteristics in finishing pigs. This effect was confirmed as TCMF extraction promoted porcine cell proliferation and affected isoforms of MyHC gene expression in myocytes.

• Journal of Biomedical Engineering Research
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• v.21 no.4
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• pp.391-401
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• 2000

Flow through compliant tubes with linear taper in wall thickness is numerically simulated by finite element analysis. For verification of the numerical method, flow through a compliant stenotic vessel is simulated and the results are compared to the existing experimental data. Steady two-dimensional flow in a collapsible channel with initial tension is also simulated and the results are compared with numerical solutions from the literature. Computational results show that as cross-sectional area decreases with the reduction in downstream pressure, flow rate increases and reaches the maximum when the speed index (mean velocity divided by wave speed) is near the unity at the point of minimum cross-section area, indicating the flow limitation or choking (flow speed equals wave speed) in one-dimensional studies. for further reductions in downstream pressure, flow rate decreases. The flow limitation or choking consist of the main reasons of waterfall effect which occurs in the airways, capillaries of lung, and other veins. Cross-sectional narrowing is significant but localized. When the ratio of downstream-to-upstream wall thickness is 2, the area throat is located near the downstream end. As this ratio is increased to 3, the constriction moves to the upstream end of the tube.

• Structural Engineering and Mechanics
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• v.85 no.4
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• pp.563-571
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• 2023

Girdling underpinning joints are key areas of concern for the pier-cutting bridge-lifting process. In this study, five specimens of an underpinning joint were prepared by varying the cross-sectional shape of the respective column, the process used to treat the beam-column interface (BCI), and the casting process. These specimens were subsequently analyzed through static failure tests. The BCI was found to be the weakest area of the joint, and the specimens containing a BCI underwent punching shear failure. The top of the girdling beam (GB) was subjected to a circumferential tensile force during slippage failure. Compared to the specimens with a smooth BCI, the specimens subjected to chiseling exhibited more pronounced circumferential compression at the BCI, which in turn considerably increased the shear capacity of the BCI and the ductility of the structure. The GB for the specimens containing a column with a circular cross-section exhibited better shear mechanical properties than the GB of other specimens. The BCI in specimens containing a column with a circular cross-section was more ductile during failure than that in specimens containing a column with a square cross-section.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.38 no.8
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• pp.658-666
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• 1989

In this paper, an efficient algorithm for estimation volume and surface area and a reconstruction algorithm for 3-dimensional graphics are presented.In order to improve computing efficiency, the graph theory is utilized and the algorithm to obtain proper contour points is developed by considering several tolerances. Search for the contour points is limited by the change of curvature of cross sectional contour to provide efficiency in searching the minimum cost path. In computer simulation of these algorithms, the results show that, for the tolerance values of 1.001 and 1.002, the execution time reduced to 66%-80% and the error for the measured value is less than 3%. The reconstructed 3-dimensional images from the cross sections can be analyzed in many directions using the graphic scheme.

• Transactions of Materials Processing
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• v.13 no.8
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• pp.671-677
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• 2004

For the large reduction in tube cross section, the tube drawing process is usually performed by two successive passes, so called first drawing and second drawing. In multi-pass drawing process, the reduction balance is important to prevent drawing cracks. Therefore in this study, the model for uniform reduction distribution in two-pass drawing process has been developed on the basis of cross sectional variation of drawn tube. For the given product geometry the model provides optimal diameter and thickness that can evenly distribute drawing reductions. The capability of model is well confirmed by finite element analysis of tube drawing process. Criteria curves at various limit strains to determine whether the drawn tube would fail during drawing process are also proposed by using newly developed model.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2002.10a
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• pp.99-103
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• 2002

A field test was peformed to estimate the thermal performance of the forced convection electric air heater by the experiment. Air temperature, flow rate and electrical power input were measured with the related measurement sensors, and acquisition methods for the measured data were studied to effectively estimate the thermal performance of the tested air heater. To determine the mean air temperature at the flow cross-section, measuring positions were chosen by considering the flow velocity profile and the equally divided cross-sectional area. From the experimental results, thermal efficiency is obtained as an indication of the tested electric air heater performance.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.11 no.6
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• pp.60-67
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• 2002

A precise measurement of field test was performed to estimate the thermal performance of the forced convection electric air heater by experiment. Air temperature, flow rate and electrical power input were measured with the related measurement sensors, and acquisition methods for the measured data were studied to estimate the thermal performance of the tested air heater effectively. To determine the mean air temperature at the flow cross-section, measuring positions were chosen by considering the flow velocity profile and the equally divided cross-sectional area. From the experimental results, thermal efficiency was obtained accurately as an indication of the tested heating system performance.

• Journal of the Korean Society for Precision Engineering
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• v.10 no.2
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• pp.40-47
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• 1993

To diversify the area of application of UBET to the analysis of ring rolling which produces rings having more complex cross-sectional configuration, an element of triangular cross-section has been introduced and the corresponding kinematically admissible velocity field has been derived while considering the material flow between neighboring elements. The theoretical perdictions in roll torque and profile formation show good agreement with the experiments. The effect of process parameters such as feed rate and taper angle of the roll groove has been discussed.

• The Korean Journal of Pain
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• v.36 no.4
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• pp.465-472
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• 2023

Background: Percutaneous radiofrequency thermocoagulation (RFTC) has been widely utilized in the management of trigeminal neuralgia. Despite using image guidance, accurate needle positioning into the target area still remains a critical element for achieving a successful outcome. This study was performed to precisely clarify the anatomical information required to ensure that the electrode tip is placed on the sensory component of the mandibular nerve (MN) at the foramen ovale (FO) level. Methods: The study used 50 hemi-half heads from 26 South Korean adult cadavers. Results: The cross-sectioned anterior and posterior divisions of the MN at the FO level could be distinguished based on an irregular boundary and color difference. The anterior division was clearly brighter than the posterior one. The anterior division of the MN at the FO level was located at the whole anterior (38.0%), anteromedial (6.0%), anterior center (8.0%), and anterolateral (22.0%) parts. The posterior division was often located at the whole posterior or posterolateral parts of the MN at the FO level. The anterior divisions covered the whole MN except for the medial half of the posterolateral part in the overwrapped images of the cross-sectional areas of the MN at the FO level. The cross-sectional areas of the anterior divisions were similar in males and females, whereas those of the posterior divisions were significantly larger in males (P = 0.004). Conclusions: The obtained anatomical information is expected to help physicians reduce unwanted side effects after percutaneous RFTC within the FO for the MN.

• Ocean and Polar Research
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• v.35 no.4
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• pp.291-298
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• 2013

In order to investigate the topography and exposure duration of the Siheung tidal flat, tidal ranges and DEM constructed by remote sensing techniques were analyzed. A cross-sectional diagram of the intertidal area reveals that it is relatively flat in the upper zone and then abruptly plunges into the bottom of the main channel where elevations increase in an upstream direction. The waterline during the Highest Low Water (HLW) is drawn back to the bottom of the channel at the middle part of the tidal flat and is formed along the slant of the channel during the Lowest High Water (LHW). The intertidal zone is located between -410 cm and 510 cm in terms of elevation and its total area is $0.65km^2$. An area between the Highest High Water (HHW) and Lowest High Water (LHW), occupying about 80% of the total area, occupies $0.52km^2$ of total area and accounts for 56% of the exposure duration. The boundary of wetland protection area in the Siheung tidal flat did not exactly coincide with the intertidal regime and differs by more than 15%. This study, which precisely analyzed the tidal flat area, tidal environment, and topography, would be useful in making a conservation plan and in learning how to use a wetland protection area in a sustainable manner.