• 센서학회지
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• 제28권3호
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• pp.146-151
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• 2019

This paper reports a sliding window filtering approach for ground moving targets with cross-correlated sensor noise and uncertainty. In addition, the effect of uncertain parameters during a tracking error on the model performance is considered. A distributed fusion sliding window filter is also proposed. The distributed fusion filtering algorithm represents the optimal linear combination of local filters under the minimum mean-square error criterion. The derivation of the error cross-covariances between the local sliding window filters is the key to the proposed method. Simulation results of the motion of the ground moving target a demonstrate high accuracy and computational efficiency of the distributed fusion sliding window filter.

• International Journal of Computer Science & Network Security
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• 제22권4호
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• pp.329-339
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• 2022

Small cells, particularly femtocells, are regarded a promising solution for limited resources required to handle the increasing data demand. They usually boost wireless network capacity. While widespread usage of femtocells increases network gain, it also raises several challenges. Interference is one of such concerns. Interference management is also seen as a main obstacle in the adoption of two-tier networks. For example, placing femtocells in a traditional macrocell's geographic area. Interference comes in two forms: cross-tier and co-tier. There have been previous studies conducted on the topic of interference management. This study investigates the principle of categorization of interference management systems. Many methods exist in the literature to reduce or eliminate the impacts of co-tier, cross-tier, or a combination of the two forms of interference. Following are some of the ways provided to manage interference: FFR, Cognitive Femtocell and Cooperative Resource Scheduling, Beamforming Strategy, Transmission Power Control, and Clustering/Graph-Based. Approaches, which were proposed to solve the interference problem, had been presented for each category in this work.

• Asian-Australasian Journal of Animal Sciences
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• 제24권10호
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• pp.1386-1392
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• 2011

The aim of the present work was to study the effects of a polyherbal supplement on cross bred does, starting from the last month of pregnancy to weaning, on milk yield, kid birth weight and growth rate. Thirty does were divided into three treatments of ten each in individual pens: low level supplementation (LS), high level supplementation (HS) and non-supplemented treatment (NS) as control. Low supplemented goats were given 125 mg/kg BW/d of polyherbal combination; high supplemented goats were given 250 mg/kg BW/d. The study was carried out in 2008. Fifty-nine kids were born from all the experimental animals. There was no difference on milk yield between supplemented groups and control (p>0.05), although polyherbal supplementation had positive effect on litter birth weight and growth rate compared to control. Weaning weights were higher (p<0.001) in LS and HS compared to NS does. In both supplemented treatments compared to control, mortalities and morbidities were also lower in kids born. It is concluded that pre-partum to weaning supplementation increases kids growth rates and weaning weights, as well as reduces kid mortalities, but it doesn't have significant effect on milk production.

• 화훼연구
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• 제18권2호
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• pp.147-150
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• 2010

1999, 2002년에 인공교배한 조합에서 선발된 계통들을 2004년부터 2006년까지 특성검정을 거쳐 최종 육성한 분화장미 신품종 '타이니볼'은 백/분홍 복합색의 왜성형 분화장미로 대비품종에 비해 꽃크기는 작은 편이나 꽃잎수와 착화수가 많으며, 수고가 낮아 왜화제 처리 없이도 상품화율이 높다.

• Child Health Nursing Research
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• 제30권2호
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• pp.77-86
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• 2024

Purpose: This study examined the combined effects of sugar-sweetened beverage (SSB) consumption, screen-based sedentary behaviors, and sleep duration on adolescent obesity. Methods: It followed a cross-sectional study design and conducted secondary analysis on data from 20,497 high school students who participated in the 17th (2021) Korea Youth Risk Behavior Web-based Survey. This study underwent logistic regression analysis in complex sampling analysis. Results: The combinations of low and medium consumption of SSBs, excessive screen-based sedentary behaviors, and short sleep durations were associated with a 1.18 and 1.12 fold increased likelihood of obesity (95% confidence interval [CI]=1.03-1.35) and (95% CI=1.02-1.22), respectively. The combination of high SSB consumption, appropriate screen-based sedentary behaviors, and short sleep duration (adjusted odds ratio [aOR]=1.15, 95% CI=1.01-1.31) and high SSB consumption, excessive screen-based sedentary behaviors, and short sleep duration (aOR=1.40, 95% CI=1.16-1.69) were associated with obesity. Conclusion: Integrated and tailored programs considering combination patterns of SSB consumption, screen-based sedentary behaviors, and short sleep duration need to be developed for preventing adolescent obesity.

• 한국작물학회지
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• 제35권6호
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• pp.532-538
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• 1990

본 연구는 유전 배경과 초형이 다른 추파소맥 4품종을 공시하였으며, 이들 품종들의 조합배열을 감안하여 단교배 6조합, 3원교배 6조합 및 복교배 3조합을 생산하여 각 교잡방법 및 품종교잡 배열순서에 관한 효율성을 비교 분석하여 교잡육종의 기초자료를 제공하고 신품종 육성의 효율성을 높이고자 시행하였던 바 그 결과를 요약하면, 1. 교배양식간 비교에 있어서 복교잡에서 가장 빠른 출수를 보였으며 종실수량도 20.3g으로서 가장 많았는데 3원교배 및 단교배 순으로 감소하였는데, 친품종들이 가장 적은 주당수량을 보였다. 2. 주당수량과 수량구성요소에 대한 4$\times$4 단교배 Diallel 분석은 GCA와 SCA에서 각각 조합능력의 차가 인정되었으며, 또한 SCA 효과중 평균 우성편차도 역시 모든 형질에서 차가 있었다. 주당수량의 GCA효과는 그루밀과 Bezostaya 1이 가장 높았으며, 이들 품종들이 실제 주당수량이 가장 많았다. 3. F$_1$의 SCA효과는 (은파밀/Bezostaya 1)조합에서 4.22로가장 높았고, (그루밀/은파밀) 조합에서 2.00으로 가장 낮았다. 4. 3조합의 F$_1$ 복교잡종중에서 (Lancota/은파밀//그루밀/Bezostaya 1) 조합이 주당수량 24.5g으로서 가장 많았고, 이러한 복교잡에 이용된 단교잡종(그루밀/은파밀)과 (Lancota/Bezostaya 1)의 복교잡에 직접 발현되지 않고 이들간의 염색체 교환방법에 의하여 결합되어 (그루밀/Lancota), (그루밀/Bezostaya 1), (은파밀/Lancota) 및 (은파밀/Bezostaya 1)의 조합이 발현되었으며, 이들의 단교배 F$_1$들의 평균 수량도 많고 SCA 효과도 높았다. 5. 3원교잡 F$_1$의 6조합중에서(Lan./Bez.//은파밀) 조합에서 21.3g으로 가장 높은 수량을 보였는데, 이들의 염색체의 상호 교환 결합에 의하여(Lancota/은파밀)과 (Bezostaya 1/은파밀) 조합이 SCA효과가 가장 컸고 평균 종실수량도 다른 3원교잡의 경우보다 많았다.

• Biomolecules & Therapeutics
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• 제32권5호
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• pp.647-657
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• 2024

Gefitinib is the well-tolerated first-line treatment of non-small cell lung cancer. As it needs analgesics during oncology treatment, particularly in the context of the coronavirus disease, where patients are more susceptible to contract high fever and sore throat. This has increased the likelihood of taking both gefitinib and antipyretic analgesic acetaminophen (APAP). Given that gefitinib and APAP overdose can predispose patients to liver injury or even acute liver failure, there is a risk of severe hepatotoxicity when these two drugs are used concomitantly. However, little is known regarding their safety at therapeutic doses. This study simulated the administration of gefitinib and APAP at clinically relevant doses in an animal model and confirmed that gefitinib in combination with APAP exhibited additional hepatotoxicity. We found that gefitinib plus APAP significantly exacerbated cell death, whereas each drug by itself had little or minor effect on hepatocyte survival. Mechanistically, combination of gefitinib and APAP induces hepatocyte death via the apoptotic pathway obviously. Reactive oxygen species (ROS) generation and DNA damage accumulation are involved in hepatocyte apoptosis. Gefitinib plus APAP also promotes the expression of Kelch-like ECH-associated protein 1 (Keap1) and downregulated the antioxidant factor, Nuclear factor erythroid 2-related factor 2 (Nrf2), by inhibiting p62 expression. Taken together, this study revealed the potential ROS-mediated apoptosis-dependent hepatotoxicity effect of the combination of gefitinib and APAP, in which the p62/Keap1/Nrf2 signaling pathway participates and plays an important regulatory role.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.362-363
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• 2012

A new cross-linkable polymer, cross-linked d-PBAB, which has the triphenylamine as the hole transporting moiety and ethynyl group as the thermal cross-linker is firstly synthesized by the combination of anionic polymerization and deprotection process. The thermal cross-linking reaction was performed at $240^{\circ}C$ for 50 min and cross-linked d-PBAB layer showed smooth surface and is not soluble at organic solvent under spin-coating of emitting layer (EML). The solution-processed PLED which was fabricated with cross-linked d-PBAB as HTL showed approximately two times higher Lmax and four times higher LEmax than those obtained from PLED with PEDOT:PSS as the HTL. These result is ascribed to better ability of cross-linked d-PBAB to block electrons and to prevent exciton-quenching than those of PEDOT : PSS at the EML interface. This results strongly suggested that cross-linked d-PBAB can be a promising material to replace conventional PEDOT : PSS. It can be suspected that PLEDwith cross-linked d-PBAB would show longer lifetime compared with that of PLED with PEDOT : PSS, and thus further studies are under investigation.

• Toxicological Research
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• 제18권2호
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• pp.139-147
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• 2002

Hantaan (HTNV) and Puumala (PUUV) viruses cause hemorrhagic fever with renal syndrome in human. In the present study, the repeated dose toxicity of the HTNV-PUUV combination vaccine was evaluated in Sprague-Dawley rats. Animals were injected subcutaneously for 28 days with dosages of 0, 0.017, 0.17 and 1.7 dose/kg body weight per day, respectively. No any significant changes of body weight, food and water consumptions were shown. There were no death and clinical findings during the experimental period. In both male and female rats, there were not significant changes in hematological and serum biochemical analysis, urinalysis, and ophthalmoscopic and histopathological examination. These results indicate that the HTNV-PUUV combination vaccine may have no toxic effects and no observed adverse effect level (NOAEL) may be over 1.7 dose/kg/day at subcutaneous route in rats.

• 생물정신의학
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• 제22권2호
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• pp.63-77
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• 2015

Objectives The combination extract of four kinds of herbs, Gastrodia elata, Liriope platyphylla, Dimocarpus longan, and Salvia miltiorrhiza, has shown to have memory improving effects in mice. The aim of this study was to investigate the efficacy and safety of the herbal mixture for improving working memory as well as microstructural changes in white matter integrity in individuals with subjective memory complaints. Methods Seventy-five individuals with subjective memory complaints were assigned to receive either placebo (n = 15) or herbal mixture (low-dose group, n = 30 and high-dose group, n = 30) supplementation in an 8-week, randomized, double-blind, placebo-controlled clinical trial. Changes in working memory performance and fractional anisotropy (FA) values reflecting white matter integrity from baseline to 8-week endpoint were assessed. Results The herbal mixture group showed an increase in working memory performance compared to the placebo group (p for interaction = 0.001). In addition, the herbal mixture group showed an increase in FA values in the temporo-parietal regions (corrected p < 0.05), which are crucially involved in working memory function and are among the most affected regions in patients with cognitive impairments. Conclusions Findings from this study indicate that the herbal mixture may be a promising therapeutic option for individuals with subjective memory complaints.