• Title/Summary/Keyword: cross sectional study

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Ex vivo High-resolution Optical Coherence Tomography (OCT) Imaging of Pleural Reaction after Pleurodesis Using Talc

  • Ahn, Yeh-Chan;Oak, Chulho;Park, Jung-Eun;Jung, Min-Jung;Kim, Jae-Hun;Lee, Hae-Young;Kim, Sung Won;Park, Eun-Kee;Jung, Maan Hong
    • Journal of the Optical Society of Korea
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    • v.20 no.5
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    • pp.607-613
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    • 2016
  • The pleura is known as an end target organ of exposure to toxic environmental materials such as fine particulate matter and asbestos. Moreover, long-term exposure to hazardous materials can eventually lead to fatal lung disease such as diffuse pleural fibrosis or mesothelioma. Chest computed tomography (CT) and ultrasound are gold standard imaging modalities for detection of advanced pleural disease. However, a diagnostic tool for early detection of pleural reaction has not been developed yet due to difficulties in imaging ultra-fine structure of the pleura. Optical coherence tomography (OCT), which provides cross-sectional images of micro tissue structures at a resolution of 2-10 μm, can image the mesothelium with a thickness of ~100 μm and therefore enables investigation of the early pleural reaction. In this study, we induced the early pleural reaction according to a time sequence after pleurodesis using talc, which has been widely used in the clinical field. The pleural reaction in talc grouped according to the time sequence (1st, 2nd, 4th weeks) showed a significant thickening (average thickness: 45 ± 7.5 μm, 80 ± 10.7 μm, 90 ± 12.5 μm), while the pleural reaction in sham and normal groups showed pleural change from normal to minimal thickening (average thickness: 16 ± 5.5 μm, 17 ± 4.5 μm, 15 ± 6.5 μm, and 12 ± 7.5 μm, 13 ± 2.5 μm, 12 ± 3.5 μm). The measurement of pleural reaction by pathologic examinations was well-matched with the measurement by OCT images. This is the first study for measuring the thickness of pleural reactions using a biophotonic modality such as OCT. Our results showed that OCT can be useful for evaluating the early pleural reaction.

Relationship between Nutrients Intakes, Dietary Quality, and Serum Concentrations of Inflammatory Markers in Metabolic Syndrome Patients (대사증후군 환자의 영양소 섭취상태 및 식사의 질과 염증지표 농도의 상관성)

  • Kim, Mi-Sung;Kim, Ju-Young;Bae, Woo-Kyung;Kim, So-Hye;Lee, Ye-Song;Na, Woo-Ri;Sohn, Cheong-Min
    • Korean Journal of Community Nutrition
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    • v.16 no.1
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    • pp.51-61
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    • 2011
  • Elevated serum concentration of inflammation markers is known as an independent risk factor of metabolic syndrome (MS) and dietary intake is an important factor to control MS. The purpose of this study was to investigated the hypothesis that inflammatory indices are associated with dietary intake and diet quality index-international (DQI-I) in subjects with MS. A cross-sectional study was conducted on 156 men and 73 postmenopausal women with MS, defined by three or more risk factors of the modified Adult Treatment Panel III criteria. Serum levels of high sensitive C-reactive protein (hs-CRP), adiponectin were examined and nutrients intake and DQI-I were assessed using a semiquantitative food frequency questionnaire. The total DQI-I score was significantly higher in female subjects ($65.87{\pm}9.86$) than in male subjects ($62.60{\pm}8.95$). There was a positive association between hs-CRP and polyunsaturated fatty acid intake (p < 0.05) and a negative association between adiponectin and lipid (p < 0.05), total sugar (p < 0.01), and total fatty acids (p < 0.05). When the subjects were divided into 5 groups by quintile according to serum adiponectin and hs-CRP level, there was no association between DQI-I score and hs-CRP levels. Moderation score of DQI-I was significantly higher in highest quintile group than the lower quintile groups. Therefore, our results provide some evidence that dietary intake and diet quality are associated with inflammation markers and dietary modification might be a predictor to decrease risk for metabolic syndrome complications. However further research is needed to develop the dietary quality index reflecting the inflammatory change by considering the dietary habit and pattern of Koreans.

Dietary and Lifestyle Factors Associated with Weight Status among Korean Adolescents from Multicultural Families: Using Data from the 2017-2018 Korea Youth Risk Behavior Surveys (우리나라 다문화가족 청소년의 체중 상태와 관련한 식생활 및 생활습관 요인 분석: 2017-2018년 청소년건강행태조사 자료를 활용하여)

  • Song, SuJin;Song, Hyojune
    • Korean Journal of Community Nutrition
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    • v.24 no.6
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    • pp.465-475
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    • 2019
  • Objectives: This study investigated dietary and lifestyle factors associated with the weight status among Korean adolescents in multicultural families. Methods: This cross-sectional study analyzed 1,751 multicultural families' adolescents who participated in the 2017-2018 Korea Youth Risk Behavior Surveys. Information on dietary and lifestyle factors was self-reported using a web-based questionnaire and this information included breakfast and foods consumption, perceived health status, alcohol drinking, smoking, physical activity, and weight control efforts. Body mass index (BMI) was calculated based on the self-reported height and body weight (kg/㎡). Weight status was assessed according to the 2017 Korean National Growth Chart: underweight (weight-for-age <5th percentiles), overweight (85th≤ BMI-for-age <95th percentiles), and obese (BMI-for-age ≥95th percentiles). Multiple logistic regression analysis was performed to examine the dietary and lifestyle factors associated with weight status after adjustment for covariates. Results: Among Korean adolescents from multicultural families, the prevalence of overweight/obesity was 20.9%, whereas about 7% of adolescents were underweight. The weight status did not show differences according to gender, school level, area of residence, and household income. Compared to adolescents who did not have breakfast during the previous week, those who had breakfast 3-4 days/week and ≥5 days/week had a 42% (p=0.021) and a 37% (p=0.009) lower prevalence of overweight/obesity, respectively. The adolescents who frequently consumed carbonated soft drinks (≥5 times/week) showed an odds ratio (OR) of 1.69 (95% CI=1.01-2.83) for overweight/obesity relative to those adolescents who did not consume carbonated soft drinks. The OR of being underweight for adolescents who ate fast food ≥3 times/week was 1.97 (95% CI=1.04-3.71) compared to those adolescents who had not eaten fast food during the previous week. Conclusions: Dietary and lifestyle factors were associated with overweight/obesity as well as underweight among Korean adolescents in multicultural families. Our findings could be used to design and provide nutrition interventions for this specific population.

Control of Short-period and Solitary Waves Using Two-rowed Impermeable Rectangular Submerged Dike (2열 불투과성 사각형 잠제를 이용한 단주기파랑 및 고립파의 제어)

  • Lee, Kwang-Ho;Jung, Sung-Ho;Ha, Sun-Wook;Kim, Do-Sam
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.22 no.4
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    • pp.203-214
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    • 2010
  • This study numerically investigates the wave control of 2-rowed Impermeable Rectangular Submerged Dike(IRSD) with an object of how to control short-period and solitary waves simultaneously based on the Bragg resonance phenomenon that elevates the wave control performance. The boundary integral method using Green formula and the 3-D one-field Model for immiscible TWO-Phase flows (TWOPM-3D) by 3-D numerical wave flume have been used for the numerical predictions for short-period and solitary waves, respectively. These numerical models were verified through the comparisons with the previously published numerical results by other researchers. Through the parametric tests of numerical experiments for short-period waves, an optimum model of 2-rowed IRSD of a lowest transmission coefficient has been found. Furthermore, the performances of 3-D wave control for solitary waves were evaluated for the various free board, crown widths and gap distance between dikes, and have been compared with those of a single-rowed IRSD. Numerical results show that a 2-rowed IRSD with a less cross sectional area than 1-rowed one improves the wave attenuation performances when it is compared to that of single-rowed IRSD. Within the test frequency ranges of the numerical simulations conducted in this study, 2-rowed IRSD with an optimum gap distance shows an outstanding improvement of the wave attenuation up to 58% compared to that of single-rowed IRSD.

Factors Affecting Asthma and Atopic Dermatitis in Korean Children: A Population-based Cross-sectional Survey (부모의 특성을 포함한 아동기 천식과 아토피 피부염의 영향요인: 제5기 2차년도(2011년) 국민건강영양조사 자료를 중심으로)

  • Yi, Yunjeong;Kim, Jisoo
    • Child Health Nursing Research
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    • v.21 no.1
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    • pp.20-27
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    • 2015
  • Purpose: The purpose of this study was to investigate factors affecting childhood asthma and atopic dermatitis. Methods: For this study, data for 1,170 children (1-11 years) from the Fifth Korean National Health and Nutrition Examination Survey (KNHANES V-2, 2011) were analyzed. First correlation matrices were computed to test the normality of every data set and then to be in accordance with the real demographic composition, data were added weight before being analyzed. Results: The child with asthma of a three generation family (OR=3.91, 95% CI [1.33, 11.45], p=.013) compared with a two generation family showed higher asthma development, and maternal asthma (OR=9.71, 95% CI [2.66, 35.40], p=.001) showed higher asthma development in child. The only factor affecting atopic dermatitis was parental perceptions of child health: poor (OR=3.40, 95% CI [1.29, 8.98], p=.014). Conclusion: These results suggest that childhood asthma and atopic dermatitis are both affected by parental perceptions of child health. Accordingly, management and support programs for children who have asthma and/or atopic dermatitis and their families should be comprehensive and also give attention to any other health problems because health perception represents quality of life.

Prevalence of sarcopenia in association with ADL, nutritional status and depression among community dwelling elderly women (지역사회 거주 여성노인들의 근감소증 실태와 일상생활능력, 영양상태, 및 우울과의 관련성 연구)

  • Shin, Yeonghee;Hong, Yong Hae;Kim, Hae-Ok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.126-134
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    • 2016
  • The aim of this cross sectional study was to examine the prevalence of sarcopenia in association with ADL, nutritional status and depression among community dwelling elderly women. The study subjects were 90 elderly women, 65 years and over, who were living in the communities of B and D metropolitan cities from May to July, 2014. The measurements were anthropometric measures, The mini-nutritional assessment instrument (MNA), ADL, IADL, MMSE, and SGDS-K were used. The mean age of the subjects was 74.7(8.22), the prevalence of sarcopenia of this population was 37.8%, almost none of them (94.4%) required assistance in ADL, 15.6% had a risk of undernutrition, and 12.2% had the symptom of depression. The sarcopenic subjects were characterized as low income, low education, living alone, and had more co-morbidity than those of the non-sarcopenic subjects. The sarcopenic subjects were undernourished, and had higher depression scores (SGDS-K), but not in the ADL, than those of the non-sarcopenic subjects. The calf and thigh circumferences, and cognitive ability were the best predictors of sarcopenia, In conclusion, low calf and thigh circumferences and low cognitive ability will increase the risk of sarcopenia in those 65 and over in community dwelling facilities and those three predictors will be useful in the early detection of sarcopenia in the future.

Dietary Intake Status among Korean Female Breast Cancer Survivors (한국 여성 유방암 경험자의 식사섭취실태)

  • Park, Myungsook;Hwang, Eunkyung;Moon, Hyeong-Gon;Noh, Dong-Young;Lee, Jung Eun
    • Korean Journal of Community Nutrition
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    • v.19 no.2
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    • pp.163-175
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    • 2014
  • Objectives: We aimed to evaluate dietary intake among female breast cancer survivors in a cross-sectional study. Methods: A total of 127 women who had breast cancer surgery at least 6 months before baseline were included. Dietary intake of female breast cancer survivors was assessed through self-reported 3 day-dietary records. To compare dietary intake between breast cancer survivors and general female population without cancer, we selected the 1:4 age matched women from the 2011 Korean National Health and Nutrition Examination Survey (KNHANES). In the KNHANES, participants were asked about their dietary intake using the 24-hour dietary recalls. We also examined whether dietary intake varied by age group, cancer stage, or time since surgery among breast cancer survivors. We used the generalized linear model to compare their dietary intakes. Results: Intakes of total energy, beta-carotene, folate, vitamin C, plant iron and fruits were lower among breast cancer survivors with longer time since surgery compared to those with shorter time (p<0.05). Breast cancer patients with higher stage at diagnosis tended to consume less legumes (p=0.01) than those with lower stage. When we compared dietary intake between breast cancer survivors and the general female population without cancer, breast cancer survivors were more likely to consume most of macro- and micro-nutrients in larger quantity (p<0.05) and adhere to healthier diet characterized by higher intakes of legumes, seed and nuts, vegetables and fishes and shells than the general female population who never had been diagnosed with cancer (p<0.05). Conclusions: Our study results suggested that the intakes of nutrients and foods varied by time since surgery and cancer stage among breast cancer survivors and dietary intakes among breast cancer survivors differed from that in the general population. Further prospective studies are warranted to explore the association between dietary intakes of specific food items and survival among Korean breast cancer survivors.

Associations among the health status, behavior, and periodontitis in Korean adults with metabolic syndrome (한국 성인 대사증후군의 건강상태 및 건강행동과 치주염의 관련성)

  • Han, Su-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.3
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    • pp.313-324
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    • 2020
  • Objectives: The aim of this study was to confirm the association among the health status, health behaviors, and periodontitis according to total, age and sex in cases of adult metabolic syndrome(MetS). Methods: This cross-sectional study used collected data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES) conducted from 2016 to 2018 with 3,394 adults with MetS aged 19-79 years. The complex samples logistic regression analysis confirmed the relevant factors for periodontitis. Results:Periodontitis was diagnosed in 43.6% of all MetS cases. Diabetes (Odds Ratio [OR]=1.554), abdominal obesity (OR=1.336), current smoking (OR=2.465), past smoking (OR=1.379), and not-using oral care products (OR=1.414) were associated with periodontitis in MetS. In the age of 19-39 years with MetS group, diabetes (OR=5.379), elevated blood pressure (OR=3.975), current smoking (OR=7.430), and not using oral care products (OR=3.356) were associated with periodontitis. In the 40-79 age group, diabetes (OR=1.398), abdominal obesity (OR=1.360), current smoking (OR=2.022), and not using oral care products (OR=1.416) were associated with periodontitis. In the male MetS group, current smoking (OR=3.119), past smoking (OR=1.625), and brushing teeth more than three times (OR=0.743) were associated with periodontitis. In the female MetS group, diabetes (OR=1.733), impaired fasting glucose (OR=1.434), abdominal obesity (OR=1.479), and not using oral care products (OR=1.992) were associated with periodontitis. Conclusions: Improvement in blood sugar control, obesity, smoking cessation, and oral health education, including how to use oral care products in all individuals with MetS may result in improved oral health. In addition, improvement in elevated blood pressure in the MetS group aged under 40 years, and brushing teeth more than three times a day in the male MetS group can reduce the risk of periodontitis. Therefore, public and oral health professionals should emphasize on the relationship between age and sex during the metabolic syndrome management program and share relevant information with patients.

Associations of serum levels of vitamins A, C, and E with the risk of cognitive impairment among elderly Koreans

  • Kim, Sung Hee;Park, Yeong Mi;Choi, Bo Youl;Kim, Mi Kyung;Roh, Sungwon;Kim, Kyunga;Yang, Yoon Jung
    • Nutrition Research and Practice
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    • v.12 no.2
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    • pp.160-165
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    • 2018
  • BACKGROUND/OBJECTIVES: Korea is quickly becoming an aged society. Dementia is also becoming a vital public health problem in Korea. Cognitive impairment as a pre-stage of dementia shares most risk factors for dementia. The aim of the present study was to determine associations of serum levels of vitamins A, C, and E with the risk of cognitive impairment among elderly Koreans. SUBJECTS/METHODS: In this cross-sectional study, a total of 230 participants aged 60-79 years from Yangpyeong cohort were included. Cognitive function was assessed by the Korean version of the Mini-Mental State Examination for Dementia Screening. The logistic multivariable regression model was applied to determine the effect of serum vitamins A, C, and E on the risk of cognitive impairment. RESULTS: There was no significant association between the risk of cognitive impairment and serum levels of vitamin A and vitamin C. There was a significant odd ratio when the second tertile group of beta-gamma tocopherol level was compared to the first tertile group [odds ratio (OR) = 0.37, 95% confidence interval (CI) = 0.14-0.98, P for trend = 0.051]. In subgroup analyses, there were significant negative associations between beta-gamma tocopherol level and the risk of cognitive impairment in men (OR = 0.17, 95% CI = 0.03-0.87, P for trend = 0.028), non-drinkers or former drinkers (OR = 0.13, 95% CI = 0.02-0.66, P for trend = 0.025), and non-smokers or former smokers (OR = 0.27, 95% CI = 0.09-0.82, P for trend = 0.017). CONCLUSION: Serum beta-gamma tocopherol levels tended to be inversely associated with the risk of cognitive impairment. Further prospective large-scaled studies are needed to examine this association.

Predictors of Wish to Undergo Cosmetic Surgery according to Experience of Cosmetic Surgery in Female College Students (여대생의 미용성형 경험 유무에 따라 미용성형욕구에 영향을 미치는 요인)

  • Lee, Haekyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.1
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    • pp.285-293
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    • 2013
  • This study was to investigate which predictors influenced the wish to undergo cosmetic surgery according to experience of cosmetic surgery in female college students. A cross-sectional descriptive design was used with self-report questionnaires, which were completed by 254 subjects. Data was analyzed with t-test and regression. There were statistically significant differences in acceptance and social motivation of cosmetic surgery and the wish to undergo cosmetic surgery in the future between the two groups. Body area satisfaction and acceptance of cosmetic surgery were significant predictors to the wish to undergo cosmetic surgery in the non-experienced group. The significant predictor of the wish to undergo cosmetic surgery for the experienced group was acceptance of cosmetic surgery. The findings from this study suggest that there is need to different approaches to discuss or council for wish to undergo cosmetic surgery according to individual cosmetic surgery experience.