• Title/Summary/Keyword: cross sectional

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Correlations between abnormalities of morphological details and DNA fragmentation in human sperm

  • Nguyen, Hiep Tuyet Thi;Dang, Hong Nhan Thi;Nguyen, Thai Thanh Thi;Nguyen, Trung Van;Dang, Thuan Cong;Nguyen, Quoc Huy Vu;Le, Minh Tam
    • Clinical and Experimental Reproductive Medicine
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    • v.49 no.1
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    • pp.40-48
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    • 2022
  • Objective: As the associations of sperm DNA fragmentation with morphology have not been examined in detail, this study aimed to investigate the relationship between abnormalities of morphological details and DNA integrity in human sperm. Methods: In this cross-sectional study, men from infertile couples were enrolled at Hue Center for Reproductive Endocrinology and Infertility, Vietnam. Conventional semen parameters, including morphological details, were analyzed following the World Health Organization 2010 criteria. Sperm DNA fragmentation was evaluated using a sperm chromatin dispersion assay. The relationships and correlations between semen parameters, sperm morphology, and the type of halosperm and the DNA fragmentation index (DFI) were analyzed. Results: Among 130 men in infertile couples, statistically significant differences were not found in the sperm halo type between the normal and abnormal sperm morphology groups. The percentage of round-head spermatozoa was higher in the DFI >15% group (16.98%±12.50%) than in the DFI ≤15% group (13.13% ±8.82%), higher values for amorphous heads were found in the DFI >15% group, and lower values for tapered heads were observed in the DFI ≤15% group; however, these differences were not statistically significant. Small-halo sperm and the DFI were positively correlated with round-head sperm (r=0.243, p=0.005 and r=0.197, p=0.025, respectively). Conclusion: The rate of general sperm morphological abnormalities in semen analysis was not related to sperm DNA integrity. However, round sperm heads were closely associated with sperm DNA fragmentation.

A Prediction Model of Exercise Level in Patients with Ankylosing Spondylitis (강직성 척추염 환자의 운동정도 예측모형)

  • Kim, Moon Ja;Lee, Eun Nam
    • Journal of Korean Academy of Nursing
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    • v.52 no.2
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    • pp.157-172
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    • 2022
  • Purpose: This study aimed to construct and test a hypothetical model to explain the predictive factors and causal pathways for exercise levels in patients with ankylosing spondylitis based on the self-determination theory. A conceptual framework was constructed assuming that autonomy support by health care providers would satisfy the three basic psychological needs of patients, which would increase their autonomous motivation for exercise, resulting in its initiation and continuation. Methods: This cross-sectional study included 221 patients with ankylosing spondylitis who were visiting rheumatology clinics in two tertiary hospitals. Health Care Climate Questionnaire-exercise regularly, Basic Psychological Needs Satisfaction scale, Behavior Regulation in Exercise Questionnaire-2, and exercise level were used to collect data. Results: The fitness of the hypothetical model met the recommended level (𝛘2/df ≤ 3, SRMR ≤ .08, RMSEA ≤ .08, GFI ≥ .90, AGFI ≥ .85, NFI ≥ .90, TLI ≥ .90, CFI ≥ .90). The model effect analysis revealed that autonomy support by health care providers had a positive effect on patients' autonomy, competence, relatedness, autonomous motivation, and exercise level. Competence and relatedness had positive effects on autonomous motivation and exercise level, respectively. Autonomous motivation had a positive effect on exercise level. Conclusion: The predictive factors of exercise level in patients with ankylosing spondylitis were autonomous motivation, health care providers' autonomy support, competence, and relatedness. Considering these factors, we recommend the development of an effective program for improving exercise levels in these patients.

The Effects of Emotional Labor and Grit on Job Satisfaction among Pediatric Nurses (일개 상급종합병원 아동간호사의 감정노동과 그릿이 직무만족도에 미치는 영향)

  • Kim, Hyo Eun;Park, Jin Hee;Seo, Eun Ji;You, Mi Ae
    • Journal of Korean Clinical Nursing Research
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    • v.28 no.3
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    • pp.251-259
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    • 2022
  • Purpose: This study aimed to identify the relationships among emotional labor, grit, and job satisfaction of pediatric nurses and factors affecting job satisfaction. Methods: A cross-sectional study was conducted on 137 pediatric nurses working in a general hospital in Seoul. Data were collected from January 1, 2022 to January 31. The data were analyzed using SPSS/WIN version 28.0.1.1. Results: The mean score of job satisfaction was 3.63±0.43 (out of 5), emotional labor was 3.70±0.39 (out of 5), and grit was 2.90±0.30 (out of 4). Job satisfaction had positively correlated with emotional labor (r=.27, p=.002) and grit (r=.65, p<.001). The regression analyses showed subcategories of grit had a significant influence on job satisfaction. The factors significantly affecting job satisfaction were persistence to achieve long-term goals (β=.39, p<.001), patient-oriented intrinsic motivation (β=.30, p<.001), and passion to become a nursing professional (β=.21, p=.004). Conclusion: These results suggested a need to increase grit for improving the job satisfaction. Furthermore, it would be necessary to develop a diverse program to increase job satisfaction for pediatric nurses by improving grit.

The Relationshipof Role Perception of Life-Sustaining Treatment and Good Death Perception with Nursing Stress on Life-Sustaining Treatment in General Hospital Nurses (종합병원 간호사의 연명의료 간호역할 인식, 좋은 죽음 인식이 연명의료 간호 스트레스에 미치는 영향)

  • Kim, Su Hyun;Jung, Mi Sook;Jang, Myoungock
    • Journal of Korean Clinical Nursing Research
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    • v.28 no.3
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    • pp.289-298
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    • 2022
  • Purpose: Nursing stress on life-sustaining treatment of nurses is a significant contributing factor to nursing care performance and patient care outcomes. We need to investigate the factors associated with nursing stress on life-sustaining treatment in hospital settings. The purpose of this descriptive study was to examine the relationship of role perception of life-sustaining treatment and good death perception with nursing stress on life-sustaining treatment among nurses in hospital settings. Methods: Using a cross-sectional study design, we recruited nurses at a hospital located in a metropolitan city in Korea. The nurses completed structured questionnaire questions which were composed of well-validated questionnaires. Descriptive statistics and hierarchical multiple regression model were utilized for data analysis. Results: A total of 205 nurses participated in the study (female 93.2%; aged 20~29 years 63.0%; single status 78.5%). In the hierarchical multiple regression model, there was a significant positive relationship between role perception of life-sustaining treatment and nursing stress on life-sustaining treatment (β=.27, p<.001). Higher education level and working at a ward setting were also significantly related to nursing stress on life-sustaining treatment (β=.13, p<.046 for education level; β=.22, p=.001 for work setting). However, there was no relationship between good death perception and nursing stress on life-sustaining treatment. Conclusion: Education programs to reduce nursing stress on life-sustaining treatment are needed to develop for nurses who have higher role perception of life-sustaining treatment with higher education level working at ward settings in hospitals.

When and How does Leader Feedback Promote Employee Creative Problem-solving Behavior? A Three-way Interaction Model of Employee Feedback Acceptance and Task Complexity (리더의 피드백은 종업원의 창의적 문제해결 행동을 촉진시키는가? 종업원의 피드백 수용정도와 직무 복잡성의 3차항 상호작용효과)

  • Suk Bong, Choi
    • Journal of Korean Society for Quality Management
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    • v.50 no.4
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    • pp.777-792
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    • 2022
  • Purpose: This paper investigates the effects of leader feedback on employee creative problem-solving behavior. It also explores the relevant conditions that maximize the above relationship from the psychological trait and task nature perspectives. Specifically we examine how employee feedback acceptance and task complexity moderate the relationship between leader's feedback behavior on follower creative problem-solving behavior. Finally the three-way interaction among leader's feedback behavior, employee feedback acceptance and task complexity is analyzed for the best conditions to maximize the positive effect of leader's feedback on creative problem solving behavior. Methods: This paper used a cross-sectional design with questionnaires administered to 411 employees working in Korean manufacturing and service firms. It applied a hierarchical regression analysis to test the hypothesized relationships including three-way interaction effect among leader's feedback behavior, follower feedback acceptance and task complexity on follower creative problem-solving behavior. Results: The empirical results of the paper indicated that the leader feedback behavior had enhanced employee creative problem-solving behavior. It was also found that follower feedback acceptance and task complexity positively moderated the relationship between leader's feedback and follower problem solving behavior. In addition, the test of three-way interaction effects also revealed that the higher the levels of both employee feedback acceptance and task complexity, the greater the positive effect of leader feedback behavior on employee creative problem solving behavior. Conclusion: This paper contributes to the leadership and creativity literatures by identifying the role of leader's behavior enhancing employee creative problem-solving behavior and the specific conditions strengthening the positive effect of leader feedback behavior on employee creative problem-solving behavior.

Factors Related to Subjective Health Status in Community-Dwelling Older Adults Living Alone on Low Income (지역사회 거주 저소득 독거노인의 주관적 건강상태 관련요인)

  • Yi, Yumi;Park, Yeon-Hwan
    • Journal of muscle and joint health
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    • v.29 no.3
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    • pp.205-217
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    • 2022
  • Purpose: This study aimed to investigate the factors affecting the subjective health status (SHS) of low-income older adults living alone. Methods: This is a cross-sectional correlational study using secondary data analysis. Sociodemographic and health-related characteristics were included in this analysis. The health-related characteristics were categorized into three domains: physical, characterized by the number of chronic diseases and fall-related factors, timed up and go, and grip strength; psychological, in terms of depression and loneliness; and social, in terms of social support. Data were analyzed using descriptive analysis, t-test, ANOVA, Pearson's correlation coefficient, and multiple linear regression analysis. Results: The mean SHS score was 2.46 out of five. Several factors influenced the SHS of low-income older adults living alone, including sex, age, level of education, monthly income, and the three domains. Four significant predictive factors of SHS in low-income older adults living alone were identified (42.5%): the number of chronic diseases, fear of falling, depression, and social support. Conclusion: SHS is a critical factor for older adults living alone on a low-income. Hence, evaluating SHS and developing interventions to improve it periodically is necessay. Such interventions should consider chronic disease management, screening and mediation for depression and fear of falling, and strengthening their social support systems.

Recent Trend in Clinical Research of Tongue Diagnosis of Cancer Patient (암 환자의 설진에 대한 최신 연구 동향)

  • Jaeho, Song;Su Bin, Park;Jee-Hyun, Yoon;Eun Hye, Kim;Seong Woo, Yoon
    • Journal of Korean Traditional Oncology
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    • v.27 no.1
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    • pp.13-23
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    • 2022
  • Objective: The purpose of this review is to analyze the clinical studies on tongue diagnosis in cancer patients. Methods: Domestic and foreign databases were used, such as Pubmed, google scholar, Wanfang med online, Scopus, and OASIS. Searching keywords were tongue diagnosis, tongue color, tongue fur, tongue inspection, cancer, tumor, neoplasm, carcinoma, etc. Studies on tongue diagnosis in cancer patients were included. The published year was limited from 2000 to June 2022. Results: Thirteen studies were enrolled. All selected studies were cross-sectional studies. Cancer patients tend to have a dark and blue-purple tongue, thick fur, yellow fur, fissure tongue, and red dots on the tongue compared with non-cancer patients. With the aggravation of cancer, the rate of patients having dark or blue, or purple tongues increased, and the patients' sublingual veins became wide and tortuous. Conclusion: This study suggests that cancer patients tend to have distinct features of tongue diagnosis. Further researches are warranted.

Association between Beverage Intake and Obesity in Korean Adults in their 20s~30s (한국 일부 20~30대 성인의 음료 섭취와 비만도와의 관련성)

  • Yeon-Kyung, Lee;Hee-Kyong, Ro;Young-Ran, Heo;Taisun, Hyun;Mi-Kyeong, Choi
    • Journal of the Korean Dietetic Association
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    • v.29 no.1
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    • pp.1-12
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    • 2023
  • The purpose of this study was to investigate the association between daily beverage intake and obesity in young adults. This cross-sectional study was conducted with 256 adults in their 20s and 30s. Obesity was evaluated by anthropometric measurement of body mass index (BMI), waist to hip ratio and waist to height ratio. In addition, the daily intake of milk, caffeinated beverages, sweetened beverages, and alcoholic beverages was investigated using the dietary record and 24-h recall methods. Based on the BMI, men and women were classified into underweight, normal, overweight and obese. Among men, 38.3% were found to be normal, 28.1% were overweight and 31.3% obese. Among women, 11.7% were underweight, 73.4% were normal, and 10.2% were overweight, which was significantly different from men. In women, the BMI of the milk consumers was significantly lower than the non-consumers. Also, the obesity indices of caffeinated beverage consumers were significantly lower than the non-consumers. An analysis of the correlation between beverage intake and the obesity index showed that the intake of caffeinated beverages among women had a significant negative correlation with the obesity index, and intake of alcoholic beverages had a significant positive correlation with waist to height ratio. This study suggests that intake of milk and caffeinated beverage may have a positive effect on obesity, whereas the intake of alcoholic beverages may have a negative effect, especially in young adult women.

Multilevel Analysis on the Risk Factors for Depression in Jeollabuk-do (우울증 위험요인에 관한 다수준 분석: 전라북도 주민을 대상으로)

  • Jungwoo, Sohn
    • Journal of agricultural medicine and community health
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    • v.47 no.4
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    • pp.268-274
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    • 2022
  • Objectives: The purpose of this study was to identify the individual and regional risk factors on depression using community-based data in Jeollabuk-do. Methods: This cross-sectional study obtained data from the Community Health Survey 2018 in Jeollabuk-do. The dependent variable was depression measured by Patient Health Questionnaire-9 (PHQ-9). The prevalence of depression was defined if total score of PHQ-9 was 10 or higher. A multilevel analysis was conducted to consider individual and regional level independent variables that could be risk factors for depression. Results: In the individual level, female gender and smokers had significantly higher odds ratios (ORs) for depression of 1.58 and 1.72, respectively. Subjects with economic activity, higher income and higher education had significantly lower ORs of 0.53, 0.41 and 0.66. In the regional level, higher greening rates and lower levels of PM2.5 had statistically lower ORs at the significance level of 10%. Conclusion: By conducting this study, risk factors associated with depression were identified in individual- and regional-level. This study suggests that health projects are needed to control regional level risk factors including community networks for mental health management in addition to the traditional individual level risk factors.

Indoxyl sulfate, homocysteine, and antioxidant capacities in patients at different stages of chronic kidney disease

  • Chen, Cheng-Hsu;Huang, Shih-Chien;Yeh, En-Ling;Lin, Pei-Chih;Tsai, Shang-Feng;Huang, Yi-Chia
    • Nutrition Research and Practice
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    • v.16 no.4
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    • pp.464-475
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    • 2022
  • BACKGROUND/OBJECTIVES: Increased levels of uremic toxins and decreased antioxidant capacity have a significant impact on the progression of chronic kidney disease (CKD). However, it remains unclear whether they interact with each other to mediate the damage of kidney function. The purpose of this study was to investigate whether uremic toxins (i.e., homocysteine and indoxyl sulfate [IS]), as well as glutathione-dependent antioxidant enzyme activities are dependently or independently associated with kidney function during different stages of CKD patients. SUBJECTS/METHODS: One hundred thirty-two patients diagnosed with CKD at stages 1 to 5 participated in this cross-sectional study. RESULTS: Patients who had reached an advanced CKD stage experienced an increase in plasma uremic toxin levels, along with decreased glutathione peroxidase (GSH-Px) activity. Plasma homocysteine, cysteine, and IS concentrations were all positively associated with each other, but negatively correlated to GSH-Px activity levels after adjusting for potential confounders in all CKD patients. Although plasma homocysteine, cysteine, IS, and GSH-Px levels were significantly associated with kidney function, only plasma IS levels still had a significant association with kidney function after these parameters were simultaneously adjusted. In addition, plasma IS could interact with GSH-Px activity to be associated with kidney function. CONCLUSIONS: IS plays a more dominant role than homocysteine and GSH-Px activity in relation to kidney function.