• Molecules and Cells
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• 제26권2호
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• pp.107-112
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• 2008

Invasion mechanisms of pathogens and counteracting defense mechanisms of plants are highly diverse and perpetually evolving. While most classical studies of plant defense have focused only on defense-specific factor-mediated responses, recent work is beginning to shed light on the involvement of non-stress signal components, especially growth and developmental processes. This shift in focus links plant resistance more closely with growth and development. In this review, we summarize our current understanding of how pathogens manipulate host developmental processes and, conversely, of how plants deploy their developmental processes for self-protection. We conclude by introducing our recent work on UNI, a novel R protein in Arabidopsis which mediates cross-talk between developmental processes and defense responses.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 1997년도 추계학술대회발표논문집; 홍익대학교, 서울; 1 Nov. 1997
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• pp.245-248
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• 1997

As the increasing the demand on information service, high-capacity and high-speed telecommunication networks are required. For the networks, very intelligent telecommunication equipments such as DCS(Digital Cross-connect System) will be employed for the fast service on the various types of information including voice, data and image. This paper considers the transmission networks composed of DCSs and optical fibers as nodes and links of the networks, respectively. For the networks, some types of restoration algorithms are compared their characteristics for their potential applications. And a distributed control algorithm is described as an empirical example which is implemented on the BDCS(Broadband Digital Cross-connect System), where the BDCS is a type of DCS developed in Korea. Finally, some remarks on the associated further researches are added.

• 한국멀티미디어학회논문지
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• 제18권2호
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• pp.168-177
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• 2015

To increase the overall utility and decrease the link delay and power consumption, a joint optimal cross-layer design of congestion control at the transport layer, link delay at the data link layer and power allocation at the physical layer for mobile ad hoc networks is considered in this paper. As opposed to previous work, the rate outage probability in this work is based on exactly closed-form; therefore, the proposed method can guarantee the globally optimal solutions to the underlying problem. The non-convex formulated problem is transformed into a convex one, which is solved by exploiting the duality technique. Finally, simulation results verify that our proposal achieves considerable benefits over the existing method.

• 대한의생명과학회지
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• 제11권2호
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• pp.103-108
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• 2005

2-Deoxyribonolactone (dL) arises as a major DNA damage induced by a variety of agents, involving free radical attack and oxidation of C1'-deoxyribose in DNA. We investigated whether dL lesions can be repaired in mammalian cells and the mechanisms underlying the role of DNA polymerase $\beta$ in processing of dL lesions. Pol $\beta$ appeared to be trapped by dL residues, resulting in stable DNA-protein cross-links. However, repair DNA synthesis at site-specific dL sites occurred effectively in cell-free extracts, but predominantly accompanied by long-patch base excision repair (BER) pathway. Reconstitution of long-patch BER demonstrated that FEN1 was capable of removing the displaced flap DNA containing a 5'-dL residue. Cellular repair of dL lesions was largely dependent on the DNA polymerase activity of Pol $\beta$. Our observations reveal repair mechanisms of dL and define how mammalian cells prevent cytotoxic effects of oxidative DNA lesions that may threaten the genetic integrity of DNA.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1995년도 춘계학술대회 논문집
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• pp.490-496
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• 1995

A four-legged mobile robot can move on the plain terrain with mobility and stability, but if there exist any obstacles on the terrain of the motion direction, it takes extra times for a mobile robot to cross those obstacles and the stability should be considered during motion. The main objevtive is the study of a quadruped which can cross obstacles with better mobility, stability and fuel economy than any other wheeled or tracked vehicles. Vertical step, isolated wall and ditch are the basic obstacles and by understanding those three cases perfectly, a quadruped can move on any mixed rough terrain as 4-legged animal moves. Each leg of a determine the crossing capability in a static analysis. A quadruped can be simplified with links and joints. By applying the research method, a quadruped can determine the control procedures as soon as it receives the terrain informations from scanner and finally can be moved as animals move with mobility and stability.

• Molecules and Cells
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• 제38권8호
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• pp.669-676
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• 2015

Genome instability, primarily caused by faulty DNA repair mechanisms, drives tumorigenesis. Therapeutic interventions that exploit deregulated DNA repair in cancer have made considerable progress by targeting tumor-specific alterations of DNA repair factors, which either induces synthetic lethality or augments the efficacy of conventional chemotherapy and radiotherapy. The study of Fanconianemia (FA), a rare inherited blood disorder and cancer predisposition syndrome, has been instrumental in understanding the extent to which DNA repair defects contribute to tumorigenesis. The FA pathway functions to resolve blocked replication forks in response to DNA interstrand cross-links (ICLs), and accumulating knowledge of its activation by the ubiquitin-mediated signaling pathway has provided promising therapeutic opportunities for cancer treatment. Here, we discuss recent advances in our understanding of FA pathway regulation and its potential application for designing tailored therapeutics that take advantage of deregulated DNA ICL repair in cancer.

• Macromolecular Research
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• 제15권3호
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• pp.225-233
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• 2007

To improve the poor mechanical and low-temperature properties of glycidyl azide polymer (GAP)-based propellants, the addition of binders was investigated using GAP and flexible polymer backbone-structural polycaprolactone (PCP) at various weight(wt) ratios, and varying the ratio of Desmodur N-100 pluriisocyanate (N-100) to isophorone diisocyanate (IPDI). Using Gee's theory, the solubility parameter of the PCP network was determined, in order to elucidate the physical and chemical interaction between GAP and PCP. The structure of the binder networks was characterized by measuring the cross-link densities and molecular weights between cross-links ($M_c$) obtained by a swelling experiment using Flory-Rhener theory. The thermal and mechanical properties of the segmented block copolyurethane (GAP-b-PCP) binders prepared by the incorporation of PCP into the binder recipes were investigated, along with the effect of the different curatives ratios.

• 비교문화연구
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• 제33권
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• pp.121-141
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• 2013

The purpose of this paper is to establish a methodology useful for identifying links between the postwar novels of Spain and Korea. We analyze the lives and actions of the characters from Nada by Carmen Laforet, and Writing on blank paper by Oh Sang Won. The characters in these novels demonstrate the challenge of adapting to the harsh reality of life because of the psychological or physical scars of war: characters such as Jungsub and Jungseo in Writing on blank paper and Juan and Andrea in Nada finally overcome their difficulties thanks to a shared sense of existential conscience and a steadfast fighting spirit; others, like Jungyun and Roman, surrender to the struggle and commit suicide, tragically succumbing to the bitter harshness of reality. Through the analysis of these novels' characters, we can empathize with the common tragedy of war-time life and death; we gain perspective on the destruction of both society and people caused by war.

• 한국정밀공학회지
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• 제13권11호
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• pp.152-162
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• 1996

A four-legged Walking Machine can move on the plain terrain with mobility and stability and stability, but if there exist any obstacles on the terrain of the motion direction, it takes extra time to cross those obstacles and the stability should be considered during motion. The main objective is the study a Quadruped which can cross obstacles with better mobility, stability and fuel economy than any other wheeled or tracked vehicles. Vertical step, isolated wall and ditch are the basic obstacles and by understanding those three cases perfectly, a Quadruped can move on any mixed rough terrain as 4-legged terrestrial vertebrates move. Each leg of a Quadruped has a limited walk space called a walking volume and this is very important to deter- mine the crossing capability in a static analysis. A Quadruped can be simplified with links and joints. By applying the research method, a quadruped can determine the control procedures as soon as it receives the terrain information from scanner and finally can move with mobility and stability.

• 비교문화연구
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• 제49권
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• pp.33-58
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• 2017

거주공간으로서의 집은 거주자들의 습관이 축적되어감에 따라 삶의 대부분을 차지하는 리듬을 낳는다. 이러한 삶의 리듬은 집과 거주자들 사이의 상호 관계를 형성하면서 내적인 의미를 생산한다. 이와 함께 우리는 무심한 몸의 습관이 삶을 구성하는 요소가 되듯이 말없는 집의 공간이 인간의 의식을 구성하는 요소로 작용하고 있음을 보게 된다. 따라서 집은 작가에게 거주지와 거주자 간에 발생하는 관계를 조명해주면서 등장인물들을 살아 움직이게 하는 문학적 자료를 제공해준다. 마르그리트 뒤라스는 이제까지 이야기되지 않았던 집의 이야기를 텍스트와 영화를 통하여 우리에게 들려주고 있다. 작가에게 거주지는 거주자의 삶의 흔적들을 드러내며 하나의 의미체를 구성한다. 삶과 존재의 흔적을 새겨놓으며 집의 내부에 있는 방과 테이블과 의자와의 관계를 보여주기도 하는 이러한 일상의 습관이 작가에게는 상상을 불러일으키는 동인이 된다. 그러면서 뒤라스는 그녀의 집에 등장인물들을 현존의 인물들로 객관화시켜 배치하는 동시에 상상의 형상을 덧붙여 놓음으로써 현실과 유토피아적 세계를 융해시키고 있다. 이러한 결합을 통해서 이제까지 숨어있던 이야기가 복원되고 재현된다.