• Journal of Sensor Science and Technology
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• v.28 no.3
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• pp.146-151
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• 2019

This paper reports a sliding window filtering approach for ground moving targets with cross-correlated sensor noise and uncertainty. In addition, the effect of uncertain parameters during a tracking error on the model performance is considered. A distributed fusion sliding window filter is also proposed. The distributed fusion filtering algorithm represents the optimal linear combination of local filters under the minimum mean-square error criterion. The derivation of the error cross-covariances between the local sliding window filters is the key to the proposed method. Simulation results of the motion of the ground moving target a demonstrate high accuracy and computational efficiency of the distributed fusion sliding window filter.

• International Journal of Computer Science & Network Security
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• v.22 no.4
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• pp.329-339
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• 2022

Small cells, particularly femtocells, are regarded a promising solution for limited resources required to handle the increasing data demand. They usually boost wireless network capacity. While widespread usage of femtocells increases network gain, it also raises several challenges. Interference is one of such concerns. Interference management is also seen as a main obstacle in the adoption of two-tier networks. For example, placing femtocells in a traditional macrocell's geographic area. Interference comes in two forms: cross-tier and co-tier. There have been previous studies conducted on the topic of interference management. This study investigates the principle of categorization of interference management systems. Many methods exist in the literature to reduce or eliminate the impacts of co-tier, cross-tier, or a combination of the two forms of interference. Following are some of the ways provided to manage interference: FFR, Cognitive Femtocell and Cooperative Resource Scheduling, Beamforming Strategy, Transmission Power Control, and Clustering/Graph-Based. Approaches, which were proposed to solve the interference problem, had been presented for each category in this work.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.10
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• pp.1386-1392
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• 2011

The aim of the present work was to study the effects of a polyherbal supplement on cross bred does, starting from the last month of pregnancy to weaning, on milk yield, kid birth weight and growth rate. Thirty does were divided into three treatments of ten each in individual pens: low level supplementation (LS), high level supplementation (HS) and non-supplemented treatment (NS) as control. Low supplemented goats were given 125 mg/kg BW/d of polyherbal combination; high supplemented goats were given 250 mg/kg BW/d. The study was carried out in 2008. Fifty-nine kids were born from all the experimental animals. There was no difference on milk yield between supplemented groups and control (p>0.05), although polyherbal supplementation had positive effect on litter birth weight and growth rate compared to control. Weaning weights were higher (p<0.001) in LS and HS compared to NS does. In both supplemented treatments compared to control, mortalities and morbidities were also lower in kids born. It is concluded that pre-partum to weaning supplementation increases kids growth rates and weaning weights, as well as reduces kid mortalities, but it doesn't have significant effect on milk production.

• FLOWER RESEARCH JOURNAL
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• v.18 no.2
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• pp.147-150
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• 2010

A new cultivar potted miniature rose (Rosa hybrida) 'Tiny Ball' was selected out of cross combination 1999 and 2002 at Gumi Floricultural Experiment Station. Characteristics trials were conducted three times from 2003 to 2006. 'Tiny Ball' came from the combination that '990905' crossed to 'Manish'. New cultivar has pink and white flower color and the shape of flower is similar to tiny ball. The number of flower petals and flowers per pot are more than those of 'POULra022' as comparison cultivar. This cultivar has low plant height without treatment of plant retardant materials, so the high quality grade ratio of potted rose is higher than that of comparison cultivar.

• Child Health Nursing Research
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• v.30 no.2
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• pp.77-86
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• 2024

Purpose: This study examined the combined effects of sugar-sweetened beverage (SSB) consumption, screen-based sedentary behaviors, and sleep duration on adolescent obesity. Methods: It followed a cross-sectional study design and conducted secondary analysis on data from 20,497 high school students who participated in the 17th (2021) Korea Youth Risk Behavior Web-based Survey. This study underwent logistic regression analysis in complex sampling analysis. Results: The combinations of low and medium consumption of SSBs, excessive screen-based sedentary behaviors, and short sleep durations were associated with a 1.18 and 1.12 fold increased likelihood of obesity (95% confidence interval [CI]=1.03-1.35) and (95% CI=1.02-1.22), respectively. The combination of high SSB consumption, appropriate screen-based sedentary behaviors, and short sleep duration (adjusted odds ratio [aOR]=1.15, 95% CI=1.01-1.31) and high SSB consumption, excessive screen-based sedentary behaviors, and short sleep duration (aOR=1.40, 95% CI=1.16-1.69) were associated with obesity. Conclusion: Integrated and tailored programs considering combination patterns of SSB consumption, screen-based sedentary behaviors, and short sleep duration need to be developed for preventing adolescent obesity.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.35 no.6
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• pp.532-538
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• 1990

This experiment was carried out to establish the efficiency of crop breeding on comparison of combination methods of single, 3-way, and double crosses and combination order of 4 winter wheat which were different in origin, source, and plant types, On comparison of 4 crossing modes, there appeared the earliest heading and the highest grain yield in double cross, and decreased in 3-way. single crosses. and parents in order, There showed the significant mean squares of GCA and SCA in 4${\times}$4 diallel analysis for grain yield and yield components. Grumil and Bezostaya 1 exhibited highest GCA effect of grain yield which appeared the actual highest grain yield. There appeared the highest SCA-effect in F$_1$ (Eunpamil/Bezostaya 1) showing 4.22. Of the 3 double crosses there exhibited the highest grain yield in F$_1$ (Grumil/Eunpamil/ /Lanota/Bezostaya 1). Two single crosses for this double cross ---F$_1$ (Grumil/Eunpamil) and F$_1$ (Lancota/Bezostaya 1) --- do not revealed directly for this yield, but combined each other by chromosome switch as combination of F$_1$ (Grumil/Lancota), F$_1$(Grumil/Bezostaya 1), F$_1$(Eunpamil/Lancota) and F$_1$(Eunpamil/Bezostaya 1) which appeared the higher grain yields and SCA-effects. Of the six 3-way crosses. F$_1$ (Lancota/Bezostaya 1/ /Eunpamil) expressed the highest grain yield. Its combinations were F$_1$ (Lancota/Eunpamil) and F$_1$ (Bezostaya 1/Eunpamil) combined by chromosome switch, which its grain yield and SCA-effect were higher.

• Biomolecules & Therapeutics
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• v.32 no.5
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• pp.647-657
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• 2024

Gefitinib is the well-tolerated first-line treatment of non-small cell lung cancer. As it needs analgesics during oncology treatment, particularly in the context of the coronavirus disease, where patients are more susceptible to contract high fever and sore throat. This has increased the likelihood of taking both gefitinib and antipyretic analgesic acetaminophen (APAP). Given that gefitinib and APAP overdose can predispose patients to liver injury or even acute liver failure, there is a risk of severe hepatotoxicity when these two drugs are used concomitantly. However, little is known regarding their safety at therapeutic doses. This study simulated the administration of gefitinib and APAP at clinically relevant doses in an animal model and confirmed that gefitinib in combination with APAP exhibited additional hepatotoxicity. We found that gefitinib plus APAP significantly exacerbated cell death, whereas each drug by itself had little or minor effect on hepatocyte survival. Mechanistically, combination of gefitinib and APAP induces hepatocyte death via the apoptotic pathway obviously. Reactive oxygen species (ROS) generation and DNA damage accumulation are involved in hepatocyte apoptosis. Gefitinib plus APAP also promotes the expression of Kelch-like ECH-associated protein 1 (Keap1) and downregulated the antioxidant factor, Nuclear factor erythroid 2-related factor 2 (Nrf2), by inhibiting p62 expression. Taken together, this study revealed the potential ROS-mediated apoptosis-dependent hepatotoxicity effect of the combination of gefitinib and APAP, in which the p62/Keap1/Nrf2 signaling pathway participates and plays an important regulatory role.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.362-363
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• 2012

A new cross-linkable polymer, cross-linked d-PBAB, which has the triphenylamine as the hole transporting moiety and ethynyl group as the thermal cross-linker is firstly synthesized by the combination of anionic polymerization and deprotection process. The thermal cross-linking reaction was performed at $240^{\circ}C$ for 50 min and cross-linked d-PBAB layer showed smooth surface and is not soluble at organic solvent under spin-coating of emitting layer (EML). The solution-processed PLED which was fabricated with cross-linked d-PBAB as HTL showed approximately two times higher Lmax and four times higher LEmax than those obtained from PLED with PEDOT:PSS as the HTL. These result is ascribed to better ability of cross-linked d-PBAB to block electrons and to prevent exciton-quenching than those of PEDOT : PSS at the EML interface. This results strongly suggested that cross-linked d-PBAB can be a promising material to replace conventional PEDOT : PSS. It can be suspected that PLEDwith cross-linked d-PBAB would show longer lifetime compared with that of PLED with PEDOT : PSS, and thus further studies are under investigation.

• Toxicological Research
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• v.18 no.2
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• pp.139-147
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• 2002

Hantaan (HTNV) and Puumala (PUUV) viruses cause hemorrhagic fever with renal syndrome in human. In the present study, the repeated dose toxicity of the HTNV-PUUV combination vaccine was evaluated in Sprague-Dawley rats. Animals were injected subcutaneously for 28 days with dosages of 0, 0.017, 0.17 and 1.7 dose/kg body weight per day, respectively. No any significant changes of body weight, food and water consumptions were shown. There were no death and clinical findings during the experimental period. In both male and female rats, there were not significant changes in hematological and serum biochemical analysis, urinalysis, and ophthalmoscopic and histopathological examination. These results indicate that the HTNV-PUUV combination vaccine may have no toxic effects and no observed adverse effect level (NOAEL) may be over 1.7 dose/kg/day at subcutaneous route in rats.

• Korean Journal of Biological Psychiatry
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• v.22 no.2
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• pp.63-77
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• 2015

Objectives The combination extract of four kinds of herbs, Gastrodia elata, Liriope platyphylla, Dimocarpus longan, and Salvia miltiorrhiza, has shown to have memory improving effects in mice. The aim of this study was to investigate the efficacy and safety of the herbal mixture for improving working memory as well as microstructural changes in white matter integrity in individuals with subjective memory complaints. Methods Seventy-five individuals with subjective memory complaints were assigned to receive either placebo (n = 15) or herbal mixture (low-dose group, n = 30 and high-dose group, n = 30) supplementation in an 8-week, randomized, double-blind, placebo-controlled clinical trial. Changes in working memory performance and fractional anisotropy (FA) values reflecting white matter integrity from baseline to 8-week endpoint were assessed. Results The herbal mixture group showed an increase in working memory performance compared to the placebo group (p for interaction = 0.001). In addition, the herbal mixture group showed an increase in FA values in the temporo-parietal regions (corrected p < 0.05), which are crucially involved in working memory function and are among the most affected regions in patients with cognitive impairments. Conclusions Findings from this study indicate that the herbal mixture may be a promising therapeutic option for individuals with subjective memory complaints.