• Tuberculosis and Respiratory Diseases
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• v.84 no.4
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• pp.274-281
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• 2021

Background: The Korea National Health and Nutrition Examination Survey (KNHANES) is a well-designed survey to collect national data, which many researchers have used for their studies. In KNHANES, although portable spirometry was used, its reliability has not been verified. Methods: We prospectively enrolled 58 participants from four Korean institutions. The participants were classified into normal pattern, obstructive pattern, and restrictive pattern groups according to their previous spirometry results. Lung function was estimated by conventional spirometry and portable spirometry, and the results were compared. Results: The intraclass correlation coefficients of forced vital capacity (FVC) (coefficient, 9.993; 95% confidence interval [CI], 0.988-0.996), forced expiratory volume in 1 second (FEV₁) (coefficient, 0.997; 95% CI, 0.995-0.998), FEV₁/FVC ratio (coefficient, 0.995; 95% CI, 0.992-0.997), and forced expiratory flow at 25-75% (FEF25-75%; coefficient, 0.991; 95% CI, 0.984-0.994) were excellent (all p<0.001). In the subgroup analysis, the results of the three parameters were similar in all groups. In the overall and subgroup analyses, Pearson's correlation of all the parameters was also excellent in the total (coefficient, 0.986-0.994; p<0.001) and subgroup analyses (coefficient, 0.915-0.995; p<0.001). In the paired t-test, FVC, FEV₁/FVC, and FEF25-75% estimated by the two instruments were statistically different. However, FEV₁ was not significantly different. Conclusion: Lung function estimated by portable spirometry was well-correlated with that estimated by conventional spirometry. Although the values had minimal differences between them, we suggest that the spirometry results from the KNHANES are reliable.

• Progress in Superconductivity and Cryogenics
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• v.8 no.1
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• pp.39-44
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• 2006

Before applying HTS power cable to the real utility. system analysis should be carried out by some simulation tools . Hereby the electrical power system analysis is very important for practical use of HTS devices. Nowadays PSCAD/EMTDC simulation tool is one of the most popular and useful analysis tool for the electrical power system analysis. Unfortunately the model component for HTS power cable is not provided in the PSCAD/EMTDC simulation tool In this paper. the EMTDC model component for HTS power cable has been developed considering critical current, critical temperature and recovery time constant that depend on the sorts of HTS wire. The numerical model of HTS Power cable in PSCAD/EMTDC was designed by using the real experimented data obtained from the real HTS 1G wire test. The utility application analysis of HTS power cable was also performed using the developed model component and the parameters of the real utility network in this study. The author's got good results. The developed model component for HTS power cable could be variously used when the power system includes HTS power cable, especially it will be readily analyzed by PSCAD/EMTDC in order to obtain the data for the level of fault current power flow, and power losses, and so on.

• Tuberculosis and Respiratory Diseases
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• v.52 no.1
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• pp.14-23
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• 2002

Background: The opitmal ventilator setting during partial liquid ventilation(PLV) is controversial. This study investigated the effects of various gas exchange parameters during PLV in normal rabbit lungs in order to aid in the development of an optimal ventilator setting during PLV. Methods: Seven New-Zealand white rabbits were ventilated in pressure-controlled mode with the following settings; tidal volume($V_T$) 8 mL/kg, positive end-expiratory pressure(PEEP) 4 $cmH_2O$, inspiratory-to-expiratory ratio(I:E ratio) 1:2, fraction of inspired oxygen($F_TO_2$) 1.0. The respiration rate(RR) was adjusted to keep $PaCO_2$ between 35~45 mmHg. The ventilator settings were changed every 30 min in the following sequence : (1) Baseline, as the basal ventilator setting, (2) Inverse ratio, I:E ratio 2:1, (3) high PEEP, adjust PEEP to achieve the same mean inspiratory pressure (MIP) as in the inverse ratio, (4) High $V_T$, $V_T$ 15 mL/kg, (5) high RR, the same minute ventilation (MV) as in the High $V_T$. Subsequently, the same protocol was repeated after instilling 18 mL/kg of perfluorodecalin for PLV. The parameters of gas exchange, lung mechanics, and hemodynamics were examined. Results: (1) The gas ventilation(GV) group showed no significant changes in the $PaO_2$ at all phases. The $PaCO_2$ was lower and the pH was higher at the high $V_T$ and high RR phases(p<0.05). No significant changes in the lung mechanics and hemodynamics parameters were observed. (2) The baseline $PaO_2$ for the PLV was $312{\pm}$ mmHg. This was significantly lower when decreased compared to the baseline $PaO_2$ for GV which was $504{\pm}81$ mmHg(p=0.001). During PLV, the $PaO_2$, was significantly higher at the high PEEP($452{\pm}38$ mmHg) and high $V_T$ ($461{\pm}53$ mmHg) phases compared with the baseline phase. However, it did not change significantly during the inverse I:E ratio or the high RR phases. (3) The $PaCO_2$ was significantly lower at high $V_T$ and RR phases for both the GV and PLV. During the PLV, $PaCO_2$ were significantly higher compared to the GV (p<0.05). (4) There were no important or significant changes in of baseline and high RR phases lung mechanics and hemodynamics parameters during the PLV. Conclusion: During PLV in the normal lung, adequate $V_T$ and PEEP are important for optimal oxygenation.

• Tuberculosis and Respiratory Diseases
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• v.48 no.6
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• pp.973-979
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• 2000

A glycogen storage disease(GSD) type I is a metabolic disease caused by a deficiency in one of the components of the glucose-6-phosphatase(G-6-Pase) system. This disorder results in hypoglycemia, hepatomegaly, lactic acidemia, hyperlipidemia, and hyperuricemia. Comon long(-)term complications include growth retaradation, gout, hepatic adenomas, osteoporosis and renal disease. However the cardiovascular system is rarely involved, and only six cases of pulmonary hypertension associated with GSD I have been reported in the literature. We experienced a case of pulmonary hypertension with type I GSD. A 31-year-old rnan, who had discovered type I GSD and received portocaval shunt operation 22 years ago, was admitted to the hospital with the chief complaint of dyspnea. Echocardiographic examination and cardiac catheterization revealed severe pulmonary hypertension. Nitric oxide and oral prostacycline derivative(beraprost) were tried without acute favorable response. After one year with beraprost, dyspnea, exercise capacity and hemodynamic parameters were improved. We report this case with a review of the literature.

• Steel and Composite Structures
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• v.22 no.6
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• pp.1417-1443
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• 2016

Cellular and castellated steel beams are used to obtain higher stiffness and bending capacity using the same weight of steel. In addition, the beam openings may be used as a pass for different mechanical fixtures such as ducts and pipes. The aim of this study is to investigate the effect of different parameters on both elastic and inelastic critical buckling stresses of steel web plates with openings. These parameters are plate aspect ratio; opening shape (circular or rectangular); end distance to the first opening; opening spacing; opening size; plate slenderness ratio; steel grade; and initial web imperfection. The web/flange interaction has been simplified by web edge restraints representing simply supported boundary conditions. A numerical parametric study has been performed through linear and nonlinear finite element (FE) models, where the FE results have been verified against both experimental and numerical results in the literature. The web plates are subject to in-plane linearly varying compression with different loading patterns, ranging from uniform compression to pure bending. A buckling stress modification factor (${\beta}$-factor) has been introduced as a ratio of buckling stress of web plate with openings to buckling stress of the corresponding solid web plate. The variation of ${\beta}$-factor against the aforementioned parameters has been reported. Furthermore, the critical plate slenderness ratio separating elastic buckling and yielding has been identified and discussed for two steel grades of DIN-17100, namely: ST-37/2 and ST-52/3. The FE results revealed that the minimum ${\beta}$-factor is 0.9 for web plates under uniform compression and 0.7 for those under both compression and tension.

• Nuclear Engineering and Technology
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• v.52 no.12
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• pp.2725-2732
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• 2020

This paper presents the neutronics benchmark analysis of the first core of the Indonesian multipurpose research reactor RSG-GAS (Reaktor Serba Guna G.A. Siwabessy) calculated by the Serpent Monte Carlo code and the newly released ENDF/B-VIII.0 nuclear data library. RSG-GAS is a 30 MWth pool-type material testing research reactor loaded with plate-type low-enriched uranium fuel using light water as a coolant and moderator and beryllium as a reflector. Two groups of critical benchmark problems are derived on the basis of the criticality and control rod calibration experiments of the first core of RSG-GAS. The calculated results, such as the neutron effective multiplication factor (k) value and the control rod worth are compared with the experimental data. Moreover, additional calculated results, including the neutron spectra in the core, fission rate distribution, burnup calculation, sensitivity coefficients, and kinetics parameters of the first core will be compared with the previous nuclear data libraries (interlibrary comparison) such as ENDF/B-VII.1 and JENDL-4.0. The C/E values of ENDF/B-VIII.0 tend to be slightly higher compared with other nuclear data libraries. Furthermore, the neutron reaction cross-sections of ¹⁶O, ⁹Be, ²³⁵U, ²³⁸U, and S(𝛼,𝛽) of ¹H in H₂O from ENDF/B-VIII.0 have substantial updates; hence, the k sensitivities against these cross-section changes are relatively higher than other isotopes in RSG-GAS. Other important neutronics parameters such as kinetics parameters, control rod worth, and fission rate distribution are similar and consistent among the nuclear data libraries.

• Tuberculosis and Respiratory Diseases
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• v.56 no.5
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• pp.523-531
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• 2004

Background : Bronchoscopy in patients on mechanical ventilation is being performed much more frequently. However, there is little data on the changes in physiologic parameters and no established mechanical ventilation protocol during bronchoscopy. A decreasing or the removal of positive end-expiratory pressure (PEEP) during bronchoscopy may precipitate severe hypoxemia and/or derecruitment. Methods : Our standardized mechanical ventilation protocol, without changing the PEEP level, was used during bronchoscopy. The physiological parameters were measured during the bronchoscopic procedure. Results : During bronchoscopy, respiratory acidosis, elevation of peak pressure, elevation of heart rate and auto-PEEP were developed, but were reversible changes. Procedure-related gross barotraumas or other severe complications did not developed. Conclusion : No serious complications developed during bronchoscopy under our standardized mechanical ventilation protocol when the PEEP level remained unchanged. The procedure time should be kept to a minimum to decrease the exposure time to undesirable physiological changes.

• Transactions on Control, Automation and Systems Engineering
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• v.4 no.1
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• pp.62-74
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• 2002

The tracking of a reference temperature trajectory in a polymerization batch reactor is a common problem and has critical importance because the quality control of a batch reactor is usually achieved by implementing the trajectory precisely. In this study, only energy balances around a reactor are considered as a design model for control synthesis, and material balances describing concentration variations of involved components are treated as unknown disturbances, of which the effects appear as time-varying parameters in the design model. For the synthesis of a tracking controller, a method combining the input-output linearization of a time-variant system with the parameter estimation is proposed. The parameter estimation method provides parameter estimates such that the estimated outputs asymptotically follow the measured outputs in a specified way. Since other unknown external disturbances or uncertainties can be lumped into existing parameters or considered as another separate parameters, the method is useful in practices exposed to diverse uncertainties and disturbances, and the designed controller becomes robust. And the design procedure and setting of tuning parameters are simple and clear due to the resulted linear design equations. The performances and the effectiveness of the proposed method are demonstrated via simulation studies.

• Structural Engineering and Mechanics
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• v.42 no.2
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• pp.153-174
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• 2012

Micromechanical facture models can be used to predict ductile fracture in steel structures. In order to calibrate the parameters in the micromechanical models for the largely used Q345 steel in China, uniaxial tensile tests, smooth notched tensile tests, cyclic notched bar tests, scanning electron microscope tests and finite element analyses were conducted in this paper. The test specimens were made from base metal, deposit metal and heat affected zone of Q345 steel to investigate crack initiation in welded steel connections. The calibrated parameters for the three different locations of Q345 steel were compared with that of the other seven varieties of structural steels. It indicates that the toughness index parameters in the stress modified critical strain (SMCS) model and the void growth model (VGM) are connected with ductility of the material but have no correlation with the yield strength, ultimate strength or the ratio of ultimate strength to yield strength. While the damage degraded parameters in the degraded significant plastic strain (DSPS) model and the cyclic void growth model (CVGM) and the characteristic length parameter are irrelevant with any properties of the material. The results of this paper can be applied to predict ductile fracture in welded steel connections.

• Geomechanics and Engineering
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• v.15 no.5
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• pp.1071-1080
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• 2018

The study of behavior and values of deformations in the geological medium makes the scientific basis of the methodology of synthesis of true values of parameters of its physico-mechanical and density properties taking into account the influence of geodynamic impacts. The segments of continuous variation of homogeneous elastic uniform deformations are determined under overall compression of the medium. The limits of these segments are defined according to the criteria of instability (on geometric form changes and on "internal" instability). Analytical formulae are obtained to calculate current and limiting (critical) values of deformations within the framework of various variants of small and large initial deformations of the non-classically linearized approach of non-linear elastodynamics. The distribution of deformation becomes non-uniform in the medium while the limiting values of deformations are achieved. The proposed analytical formulae are applicable only within homogeneous distribution of deformations. Numerical experiments are carried out for various elastic potentials. It is found that various forms of instability can precede phase transitions and destruction. The influence of these deformation phenomena should be removed while the physico-mechanical and density parameters of the deformed media are determined. In particular, it is necessary to use the formulae proposed in this paper for this purpose.