• 천문학회지
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• 제37권5호
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• pp.593-596
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• 2004

We introduce a method of identifying evidence of shocks in the X-ray emitting gas in clusters of galaxies. Using information from synthetic observations of simulated clusters, we do a blind search of the synthetic image plane. The locations of likely shocks found using this method closely match those of shocks identified in the simulation hydrodynamic data. Though this method assumes nothing about the geometry of the shocks, the general distribution of shocks as a function of Mach number in the cluster hydrodynamic data can be extracted via this method. Characterization of the cluster shock distribution is critical to understanding production of cosmic rays in clusters and the use of shocks as dynamical tracers.

• Biomolecules & Therapeutics
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• 제12권4호
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• pp.198-201
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• 2004

This review focuses on finding neurochemical changes in physical dependence on butorphanol, a relatively potent mixed agonist-antagonist opioid analgesic agent that is five times more potent than morphine in antinociceptive effects. The chronic administration of butorphanol induces physical dependence. Withdrawal from such dependence can be reliably precipitated by administration of a narcotic antagonist, e.g., naloxone. Evidence for critical involvement of excitatory aminoacid (glutamate), opioid receptors, and phosphorylation of proteins in these phenomena is summarized.

• Tuberculosis and Respiratory Diseases
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• 제79권4호
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• pp.201-206
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• 2016

Active tuberculosis (TB) has a greater burden of TB bacilli than latent TB and acts as an infection source for contacts. Latent tuberculosis infection (LTBI) is the state in which humans are infected with Mycobacterium tuberculosis without any clinical symptoms, radiological abnormality, or microbiological evidence. TB is transmissible by respiratory droplet nucleus of $1-5{\mu}m$ in diameter, containing 1-10 TB bacilli. TB transmission is affected by the strength of the infectious source, infectiousness of TB bacilli, immunoresistance of the host, environmental stresses, and biosocial factors. Infection controls to reduce TB transmission consist of managerial activities, administrative control, engineering control, environmental control, and personal protective equipment provision. However, diagnosis and treatment for LTBI as a national TB control program is an important strategy on the precondition that active TB is not missed. Therefore, more concrete evidences for LTBI management based on clinical and public perspectives are needed.

• 한국환경보건학회지
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• 제36권2호
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• pp.77-81
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• 2010

Tobacco smoking and secondhand smoke exposure are linked to a number of adverse health outcomes. There is a new concept of thirdhand smoke that is residual tobacco smoke contamination remained after the cigarette is extinguished. This paper reviews published studies examining the residual tobacco smoke. Tobacco smoke can be attached to various surfaces and reemitted to air for long period of time. The dynamic process can allow thirdhand smoke exposure to tobacco smoke without direct exposure to secondhand smoke. One critical evidence of the thirdhand smoke exposure was significantly high urinary cotinine level of infant who did not have direct secondhand smoke exposure. Potential exposure to new and more potent chemicals generated from chemical reactions between residual tobacco smoke and ambient air pollutants can get more attention. Considering toxicity and exposure route, children are uniquely susceptible to thirdhand smoke exposure. The review provides strong background information for thirdhand smoke but warrant more researches on this issue.

• 셀메드
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• 제2권3호
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• pp.24.1-24.5
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• 2012

Obesity is psychological and socioeconomic problems as well as health problems related to physical disease and disorder. The obesity epidemic, including a marked increase in the prevalence of obesity among pregnant women, represents a critical public health problem throughout the world. Gung-Gui-Tang (GGT), a prescription of traditional Korean medicine, has been used to treat dizziness due to loss of blood as well as static blood after childbirth. However, the therapeutic potential of GGT on postpartum obesity has not been fully elucidated in an experimental model. In our research, GGT inhibited the increases of body weight and adipose tissues in postpartum mice fed a high-fat diet. GGT also inhibited the elevations of plasma lipid profiles such as triglyceride, low-density lipoprotein cholesterol, total cholesterol, and glutamate pyruvate transaminase. Overall, these results provide evidence that GGT can help to inhibit postpartum obesity and open new perspective to recover the shape of mother into the moment of conception.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 추계 학술발표회
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• pp.546-552
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• 2010

Seasonal frozen ground affects structural behavior in South Korea. Frost and heaving of seasonal frozen ground results in the critical damage of roadway, railroad, and buried pipeline. It has been widely used to substitute frost susceptible soils with granular soils. This paper presents experimental investigation on the effectiveness of soil-shredded tire and soil-expanded polystylene (EPS) mixtures to reduce frost depth and force around a buried pipeline. Experimental data such as measured temperature profile and the deformation of buried pipeline were carefully observed and provide the evidence of the effectiveness of soil mixtures.

• 조명전기설비학회논문지
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• 제21권10호
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• pp.181-189
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• 2007

본 논문에서는 전기철도에서 발생하는 대지전위와 통신회선의 잡음에 대한 실험적 증명에 관한 것이다. 대지전위차가 발생하는 곳에서 전력유도잡음전압과 케이블 평형도 등을 측정할 경우 계측 오차가 심각하게 발생되는 것으로 나타났다. 측정결과, 고속철도 인접한 곳의 통신케이블은 시스층에 지전류가 많이 흐르는 차폐 케이블보다 일반 케이블을 그대로 사용하는 것이 잡음피해를 보다 줄일 수 있음이 실험 결과로 확인 되었다.

• The Plant Pathology Journal
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• 제26권1호
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• pp.1-7
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• 2010

Phosphorylation is a major post-translational modification of proteins that regulate diverse signal transduction pathways in eukaryotic cells. 14-3-3 proteins are regulatory proteins that bind to target proteins in a phosphorylation-dependent manner and have been shown to play an important role in plant growth and development, primary metabolism, and signal transduction. Because phosphorylation plays a critical role in signal transduction pathways to trigger plant immunity, involvement of 14-3-3 proteins in plant immunity has been suggested for a long time. Recent studies have provided new evidence to support a role for 14-3-3 proteins in plant immunity. This review will briefly discuss general characteristics of 14-3-3 proteins and their involvement in plant immunity.

• 경영과학
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• 제17권3호
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• pp.131-145
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• 2000

With the explosion of internet users, there are many enterprises and organizations that regard the internet as the great marketing superhighway. Although fascination and speculation surrounds the impact of the cyber shopping mall on consumer shopping behavior, there is little empirical evidence underlying all this speculation. This article reports on the critical issues that consumers found salient as they browsed through cyber shopping malls. We gathered consumers’reactions via open-ended survey. We relate the reactions to the factors of tangibility, assurance, responsibility, empathy, and reliability which we had identified from the existing literature on service quality. Two additional questionnaires were administered to translate these factors to the cyber shopping mall context and to explore their relative salience. We also evaluated SERVQUAL and SERVPERF as service quality measures for cyber shopping malls. The results show that SERVPERF seems more promising than SERVQUAL. The results also suggest that cyber shopping mall merchants need to think more about how they perform on the issues known to affect customers’decision making for purchasing. We offer advice for enhancing the design of cyber shopping mall.

• 생물정신의학
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• 제4권2호
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• pp.162-167
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• 1997

There is no doubt that dopamine plays a critical role in the etiopathogenesis of schizophrenia. However, there appeared some limitations in explaining the complex phenomena of schizophrenia. Recent research data suggest that dysfunction in serotonergic system may be involved. Before the dopamine hypothesis of schizophrenia became established, the interest in serotonin(5-hydroxytryptamine, 5-HT) as an etiological substrate of this illness occurred. Recently the importance and extent of 5-HT's involvement in the pathophysiology and mechanism of action of antipsychotic drug is actively investigated. In recent years, therapeutic success of clozapine and risperidones has increased attention on the interaction between the 5-HT and dopamine systems in schizophrenia. This led to the concept of serotonin-dopamine antagonist for antipsychotics. The authors review the evidence for the role of 5- HT in schizophrenia and serotonin-dopamine interaction.