• Journal of Powder Materials
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• v.1 no.1
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• pp.42-51
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• 1994

6061Al-SiCP metal matrix composite materials(MMCs) were fabricated by injecting SiCP particles directly into the atomized spray. The main attraction of this technique is the rapid fabrication of semi-finished, composite products in a combined atomization, particulate injection(10 $\mu\textrm{m}$, 40 $\mu\textrm{m}$, SiCP) and deposition operation. Conclusions obtained are as follows; The microstructure of the unreinforced spray formed 6061Al alloy consisted of relatively fine(50 $\mu\textrm{m}$) equiaxed grains. By comparision, the microstructure of the I/M materials was segregated and consisted of relatively coarse(150 $\mu\textrm{m}$) grains. The probability of clustering of SiCP particles in co-sprayed metal matrix composites increased it ceramic particle size(SiCP) was reduced and the volume fraction was held constant. Analysis of overspray powders collected from the spray atomization and deposition experiments indicated that morphology of powders were nearly spherical and degree of powders sphercity was deviated due to composite with SiCp particles. Interfacial bonding between matrix and ceramics was improved by heat treatment and addition of alloying elements(Mg). Maximum hardness values [Hv: 165 kg/mm2 for Al-10 $\mu\textrm{m}$ SiCp Hv--159 kg/mm2 for Al-40 $\mu\textrm{m}$SiCp] were obtained through the solution heat treatment at $530^{\circ}C$ for 2 hrs and aging at $178^{\circ}C$, and there by the resistance were improved.

• Journal of the East Asian Society of Dietary Life
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• v.20 no.5
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• pp.697-705
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• 2010

This study was designed to investigate the effect of cranberry powder making pan bread. Cranberry powder at the level of 1 % (CP1), 3% (CP3), and 5% (CP5) was mixed with flour to make the breads. According to mixograph, the control, CP1 and CP3 except CP5 were found to bo proper between 3 and 5 min. in tenn of peak time (min). All samples for peak value were at the level of over 60% It meant that all samples were proper to make bread. By increasing the ratio of cranberry powder, pH, dough fermentation rate, volume and specific volume were decreased, and adhesiveness, springiness, cohesiveness and resilience except hardness were decreased in texture profile analysis. In crumbScan analysis, the addition of cranberry powder decreased the volume and increased crumb fineness of pan bread. In sensory evaluation, CP1 and CP3 showed good preference in aspect of flavor, taste, and overall acceptance.

• Bulletin of the Korean Chemical Society
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• v.18 no.4
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• pp.402-405
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• 1997

Olefinic and cyclopropyl group substituted arenes (C6H5Y) react with [Cp*Ir(CH3COCH3)3]A2 (A=ClO4-, OTf-) to give η6-arene complexes, [Cp*Ir(η6-C6H5Y)]2+ (1a: Y=-CH=CH2 (a),-CH=CHCH3 (b),-C(CH3)=CH2 (c),-CH-CH2-CH2 (d)). Complex 1b-1d are readily converted into η3-allyl complexes, [Cp*(CH3CN)Ir(η3-CH(C6H5)CHCH2)]+ (2a) and [Cp*(CH3CN)Ir(η3-CH2(C6H5)CH2)]+ (2b), in the presence of Na2CO3 in CH3CN. The η6-styrene complex, 1a reacts with NaBH4 to give η5-cyclohexadienyl complex, [Cp*Ir(η5-C6H6-CH=CH2)]+ (3), while with H2 it gives η6-ethylbenzene complex [Cp*Ir(η6-C6H5CH2CH3)]2+ (4). Complex 1a and 1c react with HCl to give [Cp*Ir(η6-C6H5CH2CH2Cl)]2+ (5a) and [Cp*Ir(η6-C6H5CH(CH3)CH2Cl]2+ (5b), respectively.

• Korean Journal of Poultry Science
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• v.49 no.2
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• pp.79-87
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• 2022

The objective of this study was to investigate the variability in crude protein (CP) and amino acids (AA) content in cereal grains imported from different origins in Korea from 2006 to 2015. The values of CP and AA contents in corn, wheat, and barley were obtained from 430 and 325 samples from six countries, 83 and 56 samples from seven countries, and 60 and 58 samples from three countries, respectively. The CP concentrations in corn, wheat, and barley ranged from 7.12 (Brazil) to 7.68% (India), 10.55 (Ukraine) to 13.26% (Brazil), and 9.46 (India) to 10.49% (Ukraine), respectively. The Lys concentrations in the corn, wheat, and barley ranged from 0.18 (Argentina) to 0.24% (China), 0.26 (India) to 0.34% (China), and 0.23 (India) to 0.31% (Australia), respectively. The concentrations of CP and AA varied among different countries of origin (P<0.05), except for Met in wheat and CP in barley. The coefficients of variation for CP were 3.26, 9.06, and 5.36 from corn, wheat, and barley, respectively. The correlation coefficients (r) between CP and Lys concentrations in corn, wheat, and barley were positively correlated and were 0.322, 0.277, and 0.542, respectively. In conclusion, CP and AA concentrations varied not only from different countries of origins but also within the same country due to the geographic region in which they are produced.

• BMB Reports
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• v.55 no.5
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• pp.238-243
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• 2022

Autism or autism spectrum disorder (ASD) is a behavioral syndrome characterized by persistent deficits in social interaction, and repetitive patterns of behavior, interests, or activities. The gene encoding Methyl-CpG binding protein 2 (MeCP2) is one of a few exceptional genes of established causal effect in ASD. Although genetically engineered mice studies may shed light on how MeCP2 loss affects synaptic activity patterns across the whole brain, such studies are not considered practical in ASD patients due to the overall level of impairment, and are technically challenging in mice. For the first time, we show that hippocampal MeCP2 knockdown produces behavioral abnormalities associated with autism-like traits in rats, providing a new strategy to investigate the efficacy of therapeutics in ASD. Ketamine, an N-Methyl-D-aspartate (NMDA) blocker, has been proposed as a possible treatment for autism. Using the MeCP2 knockdown rats in conjunction with a rat model of valproic acid (VPA)-induced ASD, we examined gene expression and ASD behaviors upon ketamine treatment. We report that the core symptoms of autism in MeCP2 knockdown rats with social impairment recovered dramatically following a single treatment with ketamine.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.39 no.8
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• pp.14-25
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• 2002

In this paper, we propose a modified AFC algorithm which is suitable for the implementation of WCDMA reverse link receiver modem. To reduce the complexity, the modified CP-FDD algorithm named 'Normalized CP-FDD' is applied to the AFC loop. The proposed FDD algorithm overcomes the conventional CP-FDD's sensitivity to the variance of input signal amplitude and increases the linear range of S -curve. Therefore, offset frequency estimation using the proposed scheme can be more stable than the conventional method. Unlike IS-95, since pilot symbol in WCDMA is not transmitted continuously, we introduce a moving average filter at the FDD input to increase the number of cross-product. So, tracking speed and stability are improved. For more rapid frequency acquisition and tracking, we adopt a multi-stage tracking mode. Using NCO having ROM table structure, the frequency offset is compensated. We applied the proposed algorithm in the implementation of WCDMA base station modem successfully.

• Journal of the Korean Magnetic Resonance Society
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• v.18 no.1
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• pp.30-35
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• 2014

The transcription factor CP2 regulates various biological systems at diverse tissues and cells. However, none of the four CP2 isoforms has been solved in structure yet. In particular, two different regions of the CP2b isoform have been characterized to interact with the PIAS1 in nucleus to regulate the ${\alpha}$-globin gene expression. Among them, in this study, the region encompassing residues 251-309 of CP2b was prepared as a recombinant protein and its solution structure was characterized by NMR spectroscopy. The results indicated that the CP2b(251-309) fold belongs to typical IDRs (intrinsically disordered regions), likely to facilitate promiscuous interactions with various target proteins. Unfortunately, however, its interaction with the N-terminal domain of PIAS1 (residues 1-70), which has been identified as one of the CP2b-binding sites, was not observed in the NMR-based titration experiments. Therefore, it could be postulated that the 251-309 region of CP2b would not contact with the PIAS1(1-70), but alternatively interact with another CP2b-binding region that encompasses residues 400-651 of PIAS1.

• Journal of Trauma and Injury
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• v.32 no.4
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• pp.202-209
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• 2019

Purpose: Cranioplasty (CP) is often required for survival after decompressive craniectomy. Several materials, including autologous bone and various artificial materials, have been introduced for CP, but it remains unclear which material is best for CP. This study aimed to explore differences in complications between patients who underwent CP using an autologous bone flap versus a three-dimensional (3D) titanium mesh and to identify significant risk factors for post-CP complications. Methods: In total, 44 patients were enrolled in this study and divided into two groups (autologous bone vs. 3D titanium mesh). In both groups, various post-CP complications were evaluated. Through a comparative analysis, we aimed to identify differences in complications between the two groups and, using binary logistic analysis, to determine significant factors associated with complications after CP. Results: In the autologous bone flap group, there were three cases of surgical infection (3/24, 12.5%) and 11 cases of bone flap resorption (BFR) (11/24, 45.83%). In the 3D titanium mesh group, there was only one case of surgical infection (1/20, 5%) and 11 cases of various complications, including mainly cosmetic issues (11/20, 55%). A subgroup risk factor analysis of CP with an autologous bone flap showed no risk factors that predicted BFR with statistical significance, although a marginal association was found between larger bone flaps and BFR (odds ratio [OR]=1.037, p=0.090). In patients treated with a 3D titanium mesh, multivariate analysis revealed that only the existence of a ventriculo-peritoneal shunt system was strongly associated with overall post-CP complications (OR=18.66, p=0.021). Conclusions: Depending on which material was used, different complications could occur, and the rate of complications was relatively high in both groups. Hence, the material selected for CP should be selected based on individual patients' conditions.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.2231-2236
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• 2005

CP (Cellular Phone) is currently one of the most attractive technologies and RT (Robot Technology) is also considered as one of the most promising next generation technology. We present a new technological concept named RCP (Robotic Cellular Phone), which combines RT and CP. RCP consists of 3 sub-modules, $RCP^{Mobility}$, $RCP^{Interaction}$, and $RCP^{Integration}$. $RCP^{Interaction}$ is the main focus of this paper. It is an interactive emotion system which provides CP with multi-emotional signal receiving functionalities. $RCP^{Interaction}$ is linked with communication functions of CP in order to interface between CP and user through a variety of emotional models. It is divided into a tactile, an olfactory and a visual mode. The tactile signal receiving module is designed by patterns and beat frequencies which are made by mechanical-vibration conversion of the musical melody, rhythm and harmony. The olfactory signal receiving module is designed by switching control of perfume-injection nozzles which are able to give the signal receiving to the CP-called user through a special kind of smell according to the CP-calling user. The visual signal receiving module is made by motion control of DC-motored wheel-based system which can inform the CP-called user of the signal receiving through a desired motion according to the CP-calling user. In this paper, a prototype system is developed for multi-emotional signal receiving modes of CP. We describe an overall structure of the system and provide experimental results of the functional modules.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.6
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• pp.636-642
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• 2007

Background: CpG DNA plays an important role in immune cell function. This study examined whether the temporal control of toll-like receptor (TLR)9 by CpG DNA can regulate the expression of matrix metalloproteinase-9(MMP-9). Methods and materials: Macrophages were cultured in the presence of 10% FBS. For the various MMP genes analysis, RT-PCR and real-time PCR were performed. In addition, zymography assay performed for the MMP activity. The phosphorylation assay did for the ERK1/2 and NF${\kappa}B$ activation, and luciferase promoter assay was for the NF${\kappa}B$ activity. Results: CpG DNA induced the mRNA expression of MMP-2, MMP-9, and MMP-13, but not of MMP-7, MMP-8, and MMP-12, in a time-dependent manner. Especially, the mRNA expression of MMP-9 was strongly induced by CpG DNA using real-time RT-PCR. The TLR9 inhibitor, chloroquine, suppressed CpG DNA-induced MMP-9 expression and its activity. Moreover, CpG DNA induced the phosphorylation of ERK and the inhibition of ERK by U0126 suppressed CpG DNA-induced MMP-9 expression and its activity. CpG DNA stimulated $I{\kappa}B-{\alpha}$ degradation and luciferase activity. In addition, pretreatment of SN-50, the inhibitor of NF${\kappa}B$, strongly blocked the CpG DNA-induced MMP-9 expression and activity. Conclusion: These observations suggest that CpG DNA may play important roles in the activation of macrophages by regulating the production of MMP-9 via the sequential TLR9-ERK-NF${\kappa}B$ signaling pathway.