• Progress in Medical Physics
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• v.20 no.3
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• pp.152-158
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• 2009

Total Skin Electron Beam Therapy (TSEBT) of linear accelerator has become use so as to be useful, 2~9 MeV of energy territories came to be used with mycosis fungoides and cutaneous lymphomas in the superficial lesion treatment which covers the major portion of the body. I treat a patient to Stanford technique in this study, and it is $60^{\circ}$ around the patients whom Stanford technique irradiated electronic beam to a linear accelerator in horizontal directions and there is a way a standard of TSEBT treat it to six located field (anterior, posterior, and four obliques) becoming. An each field does horizontally it and consist to beam of the two component which fitted the center to a suitable angle. a patient treats it to three dual field a day in order to make short treatment time. when a first day, we treat one dual field at anterior position and two dual field at posterior position. when the second day, treat one dual field at posterior position and two dual field at anterior position. Therefore, six dual field is finished in perfect periodic two days. we made cylindrical acrylic phantom, and I inserted a dosimeter film between phantom. in order to measure a dose distribution calculation before treat a patient, and a patient checked it in six field directions that got from a treatment. It is after that thermoluminescent dosimetry (TLD) as it uses Rando phantom and then measurement dose distribution in six field directions after attaching at chest, the right and left flank, a back after irradiation.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.40 no.5
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• pp.437-447
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• 2016

In a nuclear power plant, the fuel assembly, which is composed of fuel rods, burns, and the high temperature can generate power. The fuel rod consists of pellets and a cladding that covers the pellets. It is important to understand the pellet-cladding mechanical interaction with regard to nuclear safety. This paper proposes simulation of the PCMI. The gap between the pellets and the cladding, and the contact pressure are very important for conducting thermal analysis. Since the gap conductance is not known, it has to be determined by a suitable method. This paper suggests a solution. In this study, finite element (FE) contact analysis is conducted considering thermal expansion of the pellets. As the contact causes plastic deformation, this aspect is considered in the analysis. A 3D FE module is developed to analyze the PCMI using FORTRAN 90. The plastic deformation due to the contact between the pellets and the cladding is the major physical phenomenon. The simple analytical solution of a cylinder is proposed and compared with the fuel rod performance code results.

• The Journal of the Korea Contents Association
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• v.11 no.9
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• pp.85-95
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• 2011

Recently, sudden interests of mobile cloud computing as well as conventional internet environment are rapidly increased as cloud computing spread out in our web society. Mobile devices including smart phone are rapidly changing in a wholesale way that covers hardwares, applications, and services. However, the Internet access using mobile device is not quite smooth in this local mobile internet environment which suffers from lack of understanding and observance of Web Standards. Although most of domestic web sites are developed focusing on various functions and eye-catching designs, this should became one of the main factors that make the usability and accessability decrease when accessing web with smart phones or table PCs. Therefore, this paper suggested a web interface that considered usability and accessability under mobile cloud environment and we tried to prove it via usability test. It could be found that there was an improvement of usability of interface of the main page that has been optimized to the mobile device environment suggested from the previous research we present, but this paper aimed to prove a usability improvement of total website as a whole by performing the usability test on the entire website. Selecting a special website optimized for mobile cloud computing, we prove an improvement of usability and accessibility. Therefore, we offer a guideline about user interface design applications to developers or companies who want to construct mobile website.

• Journal of Life Science
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• v.27 no.6
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• pp.726-737
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• 2017

Carotenoids are isoprenoids with a long polyene chain containing 3 to 15 conjugated double bonds, which determines their absorption spectrum. They typically consist of a $C_{40}$ hydrocarbon backbone often modified by different oxygen-containing functional groups, to yield cyclic or acyclic xanthophylls. Much work has also been focused on the identification, production, and utilization of natural sources of carotenoid (plants, microorganisms and crustacean by-products) as an alternative to the synthetic pigment which currently covers most of the world markets. Nevertheless, only a few carotenoids (${\beta}-carotene$, lycopene, astaxanthin, canthaxanthin, and lutein) can be produced commercially by fermentation or isolation from the small number of abundant natural sources. The market and demand for carotenoids is anticipated to increase dramatically with the discovery that carotenoids exhibit significant anti-carcinogenic activities and play an important role in the prevention of chronic diseases. The increasing importance of carotenoids in the feed, nutraceutical food and pharmaceutical markets has renewed by efforts to find ways of producing additional carotenoid structures in useful quantities. Because microorganisms and plants synthesize hundreds of different complex chemical carotenoid structures and a number of carotenoid biosynthetic pathways have been elucidated on a molecular level, metabolic and genetic engineering of microorganisms can provide a means towards economic production of carotenoid structures that are otherwise inaccessible. The aim of this article is to review our current understanding of carotenoid formation, to explain the perceived benefits of carotenoid in the diet and review the efforts that have been made to increase carotenoid in certain microorganisms.

• The Korean Journal of Nuclear Medicine Technology
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• v.17 no.1
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• pp.3-6
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• 2013

Purpose: The treatment of thyroid cancer patients was continuously increased. According to the increment of thyroid cancer patients, the establishment of iodine therapy site was also increased in each hospital. This treatment involves the administration of radioactive iodine, which will be given in the form of a capsule. Therefore, protections and managements for radioactive source pollution and radiation exposure should be necessary for radiation safety. Among the many problems, the problem of disposing the radioactive wastes was occurred. In this study, The date for self-disposal for radioactive wastes, which were contaminated in clothes, bedclothes and trash, were calculated. Materials and Methods: The number of iodine therapy ward was 15 in Korea Institute of Radiological Medical and Sciences. Recently, 8 therapy wards were operated for iodine therapy patients and others were on standby for emergency treatment ward of any radiation accidents. Radioactive wastes, which were occurred in therapy ward, were clothes, bedclothes, bath cover for patients washing water and food and drink which was leftover by patients. Each sample was hold into the marinelli beaker (clothes, bedclothes, bath covers) and 90 ml beaker (food, drink, and washing water). The activities of collected samples were measured by HpGe MCA device (Multi Channel Analysis, CANBERRA, USA) Results: The storage period for the each kind of radioactive wastes was calculated by equation of storage periods based on the measurement outcomes. The average storage period was 60 days for the case of clothes, and the maximum storage period was 93 days for patient bottoms. The average storage period and the maximum storage period for the trash were 69 days and 97 days, respectively. The leftover foods and drinks had short storage period (the average storage period was 25 days and maximum storage period was 39 days), compared with other wastes. Conclusion: The proper storage period for disposing the radioactive waste (clothes, bedclothes and bath cover) was 100 days by the regulation on self-disposal of radioactive waste. In addition, the storage period for disposing the liquid radioactive waste was 120 days. The current regulation for radioactive waste self-disposing was not suitable for the circumstances of each radioactive therapy facility. Therefore, it was necessary to reduce the leftover food and drinks by adequate table setting for patients, and improve the process and regulation for disposing the short-half life radioactive wastes.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.1
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• pp.69-75
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• 2016

This paper covers the result of construction and start-up tests of the KSLV(Korea Space Launch Vehicle)-II combustion chamber hot-firing test facility. This facility was constructed from 2012 to 2014. Start-up test of this facility began in the second half of 2014. Oxidizer cold flow test, fuel cold flow test and cooling water cold flow test were carried out as start-up test. Afterward, ignition test of combustion chamber was accomplished. The result of ignition test is applied to set up start-up sequence of KSLV-II combustion chamber and utilized as base line data for hot-firing test of low and normal design point.

• Wind and Structures
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• v.31 no.2
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• pp.103-142
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• 2020

One of the next frontiers in structural wind engineering is the design of tall buildings using performance-based approaches. Currently, tall buildings are being designed using provisions in the building codes and standards to meet an acceptable level of public safety and serviceability. However, recent studies in wind and earthquake engineering have highlighted the conceptual and practical limitations of the code-oriented design methods. Performance-based wind design (PBWD) is the logical extension of the current wind design approaches to overcome these limitations. Towards the development of PBWD, in this paper, we systematically review the advances made in this field, highlight the research gaps, and provide a basis for future research. Initially, the anatomy of the Wind Loading Chain is presented, in which emphasis was given to the early works of Alan G. Davenport. Next, the current state of practice to design tall buildings for wind load is presented, and its limitations are highlighted. Following this, we critically review the state of development of PBWD. Our review on PBWD covers the existing design frameworks and studies conducted on the nonlinear response of structures under wind loads. Thereafter, to provide a basis for future research, the nonlinear response of simple yielding systems under long-duration turbulent wind loads is studied in two phases. The first phase investigates the issue of damage accumulation in conventional structural systems characterized by elastic-plastic, bilinear, pinching, degrading, and deteriorating hysteretic models. The second phase introduces methods to develop new performance objectives for PBWD based on joint peak and residual deformation demands. In this context, the utility of multi-variate demand modeling using copulas and kernel density estimation techniques is presented. This paper also presents joined fragility curves based on the results of incremental dynamic analysis. Subsequently, the efficiency of tuned mass dampers and self-centering systems in controlling the accumulation of damage in wind-excited structural systems are investigated. The role and the need for explicit modeling of uncertainties in PBWD are also discussed with a case study example. Lastly, two unified PBWD frameworks are proposed by adapting and revisiting the Wind Loading Chain. This paper concludes with a summary and a proposal for future research.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3731-3740
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• 2012

Background: There have been few studies of Asian ovarian cancer and benign tumors. The primary aim of this paper was to report the protocol of the Ko-EVE study to examine epidemiological and molecular factors for ovarian cancer and benign neoplasms and to ascertain the major risk factors for ovarian cancer control in Korea. Methods: This case-control study covers incident epithelial ovarian cancers and benign neoplasms, four major centers participating in enrolling incident cases and 3 hospitals enrolling healthy controls among health examinees. Standardized questionnaires were administered by trained interviewers, including sections on socio-demographics characteristics, past medical history, medication usage, family history, lifetime consumption of alcohol and tobacco, diet, physical activity, and reproductive factors for women. Various biological specimens were collected in the biorepository according to the standardized protocol. Annual follow-up for cancer cases and follow-up at the 1st year for benign tumor cases are performing to evaluate treatment effect and progression. Passive follow to see long-term survival will be conducting using record linkage with national data. Results: The total number recruited in 2010-2011 was 246 epithelial ovarian cancer cases, 362 benign epithelial tumors and 345 controls. We are planning to collect subjects for at least 1,500 sets of ovarian cancer, 2,000 benign tumors and 1,500 controls till 2018. Conclusions: The Ko-EVE will provide unique and important data to probe the etiology and natural history of Korean epithelial ovarian cancer. It will be continued by genomic and proteomic epidemiological analyses and future intervention studies for the prevention of ovarian cancer among Koreans.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.19 no.4
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• pp.81-99
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• 2020

Origin-destination data have been collected and utilized for demand analysis and service design in various fields such as public transportation and traffic operation. As the utilization of big data becomes important, there are increasing needs to store raw origin-destination data for big data analysis. However, it is not practical to store and analyze the raw data for a long period of time since the size of the data increases by the power of the number of the collection points. To overcome this storage limitation and long-period pattern analysis, this study proposes a methodology for compression and origin-destination data analysis with the compressed data. The proposed methodology is applied to public transit data of Sejong and Seoul. We first measure the reconstruction error and the data size for each truncated matrix. Then, to determine a range of principal components for removing random data, we measure the level of the regularity based on covariance coefficients of the demand data reconstructed with each range of principal components. Based on the distribution of the covariance coefficients, we found the range of principal components that covers the regular demand. The ranges are determined as 1~60 and 1~80 for Sejong and Seoul respectively.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.9
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• pp.26-37
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• 2016

The core technologies of the current transport network are OAM and protection switching to meet the sub-50ms protection switching time via a path redundancy when a link or node failure occurs. The transport networks owned by public network operators, central/local governments, and major enterprises are individually configured and managed with service resiliency in each own protected sub-network. When such networks are cascaded, it is also important to provide a node resiliency between two protected sub-networks. However, the linear protection switching in packet transport networks, such as MPLS-TP and Carrier Ethernet, does not define a solution of dual node interconnection. Although Ethernet ring protection switching covers the dual node interconnection scheme, a large amount of duplicated data frames may be flooded when a failure occurs on an adjacent (sub) ring. In this paper, we suggest a dual node interconnection scheme with linear protection switching technology in multiple protected sub-networks. And we investigate how various protected sub-network combinations with a proposed linear or ring protection process impact the service resiliency of multiple protected sub-networks through extensive experiments on link and interconnected node failures.