• Journal of Biomedical Engineering Research
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• v.13 no.3
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• pp.181-188
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• 1992

This paper provides an overview of system analysis of immunology. The theoretical research in this area is aimed at an understanding of the precise manner by which the immune system controls Infec pious diseases, cancer, and AIDS. This can provide a systematic plan for immunological experimentation by means of an integrated program of immune system analysis, mathematical modeling and computer simulation. Biochemical reactions and cellular fission are naturally modeled as nonlinear dynamical processes to synthesize the human immune system! as well as the complete organism it is intended to protect. A foundation for the control of tumors is presented, based upon the formulation of a realistic, knowledge based mathematical model of the interaction between tumor cells and the immune system. Ordinary bilinear differential equations which are coupled by such nonlinear term as saturation are derived from the basic physical phenomena of cellular and molecular conservation. The parametric control variables relevant to the latest experimental data are also considered. The model consists of 12 states, each composed of first-order, nonlinear differential equations based on cellular kinetics and each of which can be modeled bilinearly. Finally, tumor control as an application of immunotherapy is analyzed from the basis established.

• Tribology and Lubricants
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• v.16 no.1
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• pp.39-45
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• 2000

In this paper, the effects of shaft and bearing flexibilities are investigated for the accurate modeling of a shaft-bearing system supported by ball bearings. Generally, rolling bearings are modeled by simple rigid pin-joint in the mechanical design. However, they can no longer be modeled by ideal boundary conditions in the advanced applications because the rigid pin-joint model cannot satisfy the current trends of mechanical design decreasing mass and reducing volume. Consequently the flexible support model of ball bearing is investigated using the static analysis module developed by A .B. Jones and T. A. Harris. A simple two-bearing system, supported by two deep groove ball bearings and radially loaded on the shaft midway between the bearings, is utilized to validate the coupled model of shaft-bearing system. Numerical computations using the model indicate that the shaft span length, locating/floating bearing arrangements and applied bearing size are significant factors in determining the mechanical behaviors. The flexible support model of ball bearing can be escaped to over-estimate in the bearing fatigue life. The proposed simple design formulation obtained by numerical simulations can approximately predict a rate of bearing life reduction as a function of shaft span length/shaft diameter (L/d).

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2006.11a
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• pp.351-354
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• 2006

In underwater environment, the control of AUV is difficult, because of the existence of parameter uncertainties and disturbances as well as highly nonlinear and coupled system dynamics. The requirement for the simple and robust controller which works satisfactorily in those dynamical uncertainties, call for a design using the PD or sliding mode controller. The PD controller is very popular controller in the industrial field and the sliding mode controller has been used successfully for the AUV controller design. In this paper, the two controllers arc designed for ISiMI(Integrated Submergible Intelligent Mission Implementation) AUV and the performances are compared by numerical simulation under the modeling uncertainty and disturbances. The design process of PD and sliding mode controller for ISiMI AUV and simulation results are included to compare the performances of the two controllers.

• Transactions of the Korean Society of Automotive Engineers
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• v.12 no.4
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• pp.154-162
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• 2004

In this study, a mathematical model for analyzing the shifting transients of the passenger car with an automatic transmission is proposed. The proposed model comprises a power transmission system and a vehicle system, which are coupled. In order to extract the modeling parameters, on-road car test is carried out. The model is composed of a detailed powertrain, an engine/AT housing, a simplified suspension system, tires and a vehicle body model. On the test, the vehicle accelerations and pitch ratio are measured by using accelerometers and a gyro sensor. The speeds, the brake signal, and the throttle position are taken from sensors which already exist in the vehicle. Considering natural ftequencies, which is calculated from the measured accelerations, and the characteristic equation, vehicle model parameters are identified. Dynamic behaviors during upshift or downshift are simulated using the proposed vehicle model. By comparing and analyzing the simulation result and on-road car test data, the vibration of the Engine/AT housing influences the shifting transients. The effect of model parameters are also studied. Among model parameters, the location of engine mountings influences the vibration of the vehicle body.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2007.04a
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• pp.3-17
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• 2007

This paper provides an introduction to life-span simulation and numerical approach to support the performance design processes of reinforced concrete structures. An integrated computational system is proposed for life-span simulation of reinforced concrete. Conservation of moisture, carbon dioxide, oxygen, chloride, calcium and momentum is solved with hydration, carbonation, corrosion, ion dissolution. damage evolution and their thermodynamic/mechanical equilibrium. Coupled analysis of mass transport and damage mechanics associated with steel corrosion is presented for structural performance assessment of reinforced concrete. Multi-scale modeling of micro-pore formation and transport phenomena of moisture and ions are mutually linked for predicting the corrosion of reinforcement and volumetric changes. The interaction of crack propagation with corroded gel migration can also be simulated. Two finite element codes. multi-chemo physical simulation code (DuCOM) and nonlinear dynamic code of structural reinforced concrete (COM3) were combined together to form the integrated simulation system. This computational system was verified by the laboratory scale and large scale experiments of damaged reinforced concrete members under static loads, and has been applied to safety and serviceability assessment of existing structures. Based on the damage details predicted by the nonlinear finite element analytical system, the life-span-cost of RC structures including the original construction costs and the repairing costs for possible damage during the service life can be evaluated for design purpose.

• Structural Engineering and Mechanics
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• v.36 no.4
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• pp.499-511
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• 2010

This paper examines the ice cover effects on the seismic response of concrete gravity dam-reservoir-foundation interaction systems subjected to a horizontal earthquake ground motion. ANSYS program is used for finite element modeling and analyzing the ice-dam-reservoir-foundation interaction system. The ice-dam-reservoir interaction system is considered by using the Lagrangian (displacementbased) fluid and solid-quadrilateral-isoparametric finite elements. The Sariyar concrete gravity dam in Turkey is selected as a numerical application. The east-west component of Erzincan earthquake, which occurred on 13 March 1992 in Erzincan, Turkey, is selected for the earthquake analysis of the dam. Dynamic analyses of the dam-reservoir-foundation interaction system are performed with and without ice cover separately. Parametric studies are done to show the effects of the variation of the length, thickness, elasticity modulus and density of the ice-cover on the seismic response of the dam. It is observed that the variations of the length, thickness, and elasticity modulus of the ice-cover influence the displacements and stresses of the coupled system considerably. Also, the variation of the density of the ice-cover cannot produce important effects on the seismic response of the dam.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.201-206
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• 2006

Earth sciences is undergoing a gradual but massive shift from description of the earth and earth systems, toward process modeling, simulation, and process visualization. This shift is very challenging because the underlying physical and chemical processes are often nonlinear and coupled. In addition, we are especially challenged when the processes take place in strongly heterogeneous systems. An example is two-phase fluid flow in rocks, which is a nonlinear, coupled and time-dependent problem and occurs in complex porous media. To understand and simulate these complex processes, the knowledge of underlying pore-scale processes is essential. This paper presents a new attempt to use pore-scale simulations for understanding physical properties of rocks. A rigorous pore-scale simulator requires three important traits: reliability, efficiency, and ability to handle complex microstructures. We use the Lattice-Boltzmann (LB) method for singleand two-phase flow properties, finite-element methods (FEM) for elastic and electrical properties of rocks. These rigorous pore-scale simulators can significantly complement the physical laboratory, with several distinct advantages: (1) rigorous prediction of the physical properties, (2) interrelations among the different rock properties in a given pore geometry, and (3) simulation of dynamic problems, which describe coupled, nonlinear, transient and complex behavior of Earth systems.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2002.10b
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• pp.229-230
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• 2002

This paper presents the hot spot behaviors on the rubbing surface of ventilated disk brake by using finite element method. The depth of asperities on the rubbing surface is usually $2-3\;{\mu}m$ so the real contact area is microscopically. Non-uniform contacts between the disk and the pads lead to high local temperatures, which may cause the material degradation, and develops hot spots, thermal cracking, and brake system failures at the end. High contact asperity flash temperatures in rubbing systems, which is strongly related to the hot spot. It was generally known that high temperature over about $700^{\circ}C$ may form martensite on the cast iron which is material for automotive disk brakes. In this paper, the contact stress, temperature distribution and strain have been presented for the specific asperities of real contact area microscopically by using coupled thermal-mechanical analysis technique.

• Journal of the Korea Institute of Military Science and Technology
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• v.17 no.6
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• pp.800-809
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• 2014

The gridded environmental data is usually provided by the numerical simulation coupled with a data assimilation technique and various inter- or extrapolation algorithms, both of which are based on the observation spanning from simple equipments to satellites. But it is difficult to represent the natural phenomenon such as sea mount, internal-wave, warm eddy in modeling or observation because of increase in the complexity of model. This paper introduces the algorithm artificially representing the natural phenomenon and the techniques applying it to the gridded volume data and smoothing for natural effects. Moreover, the inserted results are analyzed by use of graphical tool. The results can be used for the battle simulation or acoustic model.

• Journal of Environmental Science International
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• v.3 no.1
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• pp.17-29
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• 1994

An one dimensional atmosphere-vegetation interaction model is developed to discuss of the effect of vegetation on heat flux in mesoscale planetary boundary layer. The canopy model was a coupled system of three balance equations of energy, moisture at ground surface and energy state of canopy with three independent variables of $T_f$(foliage temperature), $T_g$(ground temperature) and $q_g$(ground specific humidity). The model was verified by comparative study with OSUID(Oregon State University One Dimensional Model) proved in HYPEX-MOBHLY experiment. As the result, both vegetation and soil characteristics can be emphasized as an important factor iii the analysis of heat flux in the boundary layer. From the numerical experiments, following heat flux characteristics are clearly founded simulation. The larger shielding factor(vegetation) increase of $T_f$ while decrease $T_g$. because vegetation cut solar radiation to ground. Vegetation, the increase of roughness and resistance, increase of sensible heat flux in foliage while decrease the latent heat flux in the foliage.