• 제목/요약/키워드: counting formula

검색결과 33건 처리시간 0.025초

ICR 마우스 골수세포를 이용한 십전대보탕 소핵시험 (Micronucleus test of Sipjeondaebo-tang extract using the bone marrow cells in ICR mice)

  • 마진열;이남헌;황대선;하혜경;유영법;신현규
    • 대한한의학방제학회지
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    • 제16권1호
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    • pp.109-115
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    • 2008
  • Objectives : This study was to assessment the toxicity of Sipjeondaebo-tang(Shiquan dabu-decoction) by micronucleus test. Methods : Sipjeondaebo-tang(Shiquan dabu-decoction) water-extract in vivo micronucleus test was performed using 7 weeks ICR mice. At 24 hours after with Sipjeondaebo-tang extract at the doses of 0, 500, 1000 and 2000 mg/kg/day by peritoneal route mice were sacrificed and bone marrow cells were prepared for smear slides. Results : As a result of counting the micronucleus polychromate erythrocyte of 2000 polychromate erythrocyte, all treatment groups did not show statistically significant increase than negative control group. and there was no clinical sign and body weight connected with injection of Sipjeondaebo-tang(Shiquan dabu-decoction) extract. Conclusions: It was concluded that Sipjeondaebo-tang extract did not induce micronucleus in the bone marrow cells of ICR mice

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총백혈구수(總白血球數), 호산구수(好酸球數) 및 기타 백혈구수(白血球數)의 직접계산(直接計算)을 위한 개량희석액(改良稀釋液)에 관한 연구(硏究) (Study on Improved Diluting Fluids for Direct Counts of Total Leukocyte, Eosinophil and Other Leukocytes)

  • 이방환
    • 대한수의학회지
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    • 제16권2호
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    • pp.105-114
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    • 1976
  • The study was conducted for an attempt to improve the diluting fluid for total leukocyte count, and to prepare a multipurpose diluting fluid for concurrent direct counts of total leukocytes, eosinophils and the other leukocytes. Through the experiment, two better fluids for total leukocyte count of blood of human, bovine, swine, canine and rabbit were selected, and which conserved cell morphology of leukocytes better than $T{\ddot{u}}rk$-solution. Each formula of two fluids were given as under R I and R II. Formula of multipurpose diluting fluid selected in the experiment was given as under III. With this fluid, direct counts of total leukocytes, eosinophils and probably basophils of blood of human, bovine and swine were practicable concurrently in the same counting chamber of a hemocytometer. In this fluid, eosinophils were stained red in the part of eosinophilic granules and blue in other part of cell, and basophils were stained dark blue like as a lump of black granules, staining three other leukocytes faint blue. Eosinophils of canine blood were not so enough red those in other animal and human and eosinophils of rabbit blood were not distinguishable from pseudoeosinophils in this fluid.

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COMPUTING THE NUMBER OF POINTS ON GENUS 3 HYPERELLIPTIC CURVES OF TYPE Y2 = X7 + aX OVER FINITE PRIME FIELDS

  • Sohn, Gyoyong
    • Journal of applied mathematics & informatics
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    • 제32권1_2호
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    • pp.17-26
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    • 2014
  • In this paper, we present an algorithm for computing the number of points on the Jacobian varieties of genus 3 hyperelliptic curves of type $y^2=x^7+ax$ over finite prime fields. The problem of determining the group order of the Jacobian varieties of algebraic curves defined over finite fields is important not only arithmetic geometry but also curve-based cryptosystems in order to find a secure curve. Based on this, we provide the explicit formula of the characteristic polynomial of the Frobenius endomorphism of the Jacobian variety of hyperelliptic curve $y^2=x^7+ax$ over a finite field $\mathbb{F}_p$ with $p{\equiv}1$ modulo 12. Moreover, we also introduce some implementation results by using our algorithm.

Afreeca TV의 인기 채널 특징 탐구 (Exploring the Traits of Popular Channels of Afreeca TV)

  • 한석희
    • 한국인터넷방송통신학회논문지
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    • 제17권2호
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    • pp.33-38
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    • 2017
  • 본 연구는 현재 한국에서 가장 대중적인 인터넷 방송 Afreeca TV에서 나타나는 인기 채널에 대하여 탐구한다. 기술의 발전으로 인해 일반인이 장비를 통해 개인 방송을 할 수 있는 시대가 도래 하였으며, 이에 따른 다양한 학술적 논의가 태어나고 있다. 인터넷 방송은 기존의 미디어와는 다르게, 시청률의 개념은 존재하지 않으며. Afreeca TV는 특정 공식을 이용하여 인기 채널을 집계한다. 이러한 상황에서 본 연구는 Afreeca TV에서 나타나는 인기 채널을 1) 성별 2) 프로필 사진 3) 장르 4) 애청자 5) 팬클럽 6) 서포터 7) 방송시간 8) 누적 시청자의 방식으로 구분하여, 어떠한 특징이 있는지 살펴보도록 한다. 더 나아가, 인터넷 방송의 미래에 대해서 고찰한다.

三重水素($^{3}H$) 放射能의 生理分析에 關한 硏究 (A Study on Bioassay of Tritium($^{3}H$) Radioacitivity)

  • 황선태;오필재;김원식
    • 한국대기환경학회지
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    • 제3권1호
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    • pp.27-33
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    • 1987
  • 삼중수소 ($^{3}H$) 에 관한 환경 및 생물학상의 연구는 1950년대 중반부터 선진국에서 수행되오고 있다. 삼중소소에 대한 잠재적 노출의 경우 통상적 처리절차는 삼중수소의 신체부하량이라고 일컬어지는 이른바 신체내에 축적된 삼중수소의 양을 결정하기 위하여 삼중수소수로서 오줌속에 포함되는 삼중수소 방사능의 생리분석이다. 전신에 있어서 삼중수소의 최대허용신체부하량은 신체조직에 대하여 약 $30{\mu}Ci/{\ell}$ 이다. 생리분석에서 오줌속에 삼중수소를 검출하는데 가장 보편적인 조사준위(照射准尉)는 최대허용신체부하량의 1/10 이다. 이러한 생리분석 연구계획을 위해서는 소광보정(消光補正) 곡선을 그리는 것이 가장 우선적이다. 이것은 검뇨용 오줌의 색깔이 일정하지 않기 때문에 필요한 것이다. 이 경우에서 소광효과는 주로 오줌시료에 의한 섬광빛의 흡수에 기인된다. 소광보정곡선으로 판단된 공식은 통계적 근거에서 최소자승법에 의하여 Y (%) = 0.771 + 1.836 ${\tmes}10^{-4}$X(count)로 얻어졌다. 여기서 Y는 섬광계수 효율로서 약 12%에서 31% 범위의 값으로 나타났다. 본 논문에서는 삼중수소의 생물학적 반감기와 신체계통적으로 분포된 삼중수소에 적용되고 있는 정체(停滯) 공식에 관한 간략한 이론에 관하여 서술된다.

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운동기술훈련이 태아알코올증후군 흰쥐 모델의 소뇌 발달과 운동기능에 미치는 영향 (The Effect of Motor Skill Training on Motor Function and Cerebellar Development After Alcohol Exposure in Neonatal Rats)

  • 구현모
    • 한국전문물리치료학회지
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    • 제16권2호
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    • pp.50-58
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    • 2009
  • The purpose of this study was to test that motor skill training enhance motor function and cerebellar development. Using an animal model of fetal alcohol syndrome-which equates peak blood alcohol concentrations across developmental period-critifical periods for the effect of alcohol on body and cerebellar weigh was examined. The effect of motor skill training on motor function and cerebellar development of rat exposed alcohol on postnatal days 4 through 10 were studied. Newborn rats were assigned to one of two groups: (1) Control group (CG), via artificial rearing to milk formula and (2) experimental groups (EG), via 4.5g/kg/day of ethanol in a milk solution. After completion of the treatments, the pups were fostered back to lactating dams, and wearing they were raised in standard caged until they were postnatal 48 days. Rats from experimental group of postnatal treatment then spent 10 days in one of two groups: Experimental group II (EGII) was had got motor skill training (training traverse a set of 6 elevated obstacles) for 4 weeks. Experimental group I (EGI) was not trained. Before sacrificing, the rat got examined two behavioral test, body weigh and cerebellar weigh, then coronal sections were processed. The section was investigated the Purkije cell in the cerebellum using light microscope. The results of this study were as follows. 1. In body weight test, the outcome of alcohol groups were significantly lower than the normal group. 2. In cerebellar weight test, the outcome of EGI were significantly lower than CG and EGII. 3. In motor behavioral test, the outcome of EGI was significantly lower than NG and EGII. 4. In Purkinje cells counting test, the outcome of EGI was significantly lower than the NG and EGII. These result suggest that improved motor function induced by motor skill training after postnatal exposure is associated with dynamically altered expression of Purkinje cells and that is related with cerebellar function. Also, these data can potentially serve as a model for therapeutic intervention.

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주파수 도약용 표본클럭 합성 계수 방식의 직접 디지틀 주파수 합성기 구현에 관한 연구 (A Study on the Implementation of Direct Digital Frequency Synthesizer using the synthesized Clock Counting Method to make the State of randomly Frequency Hopping)

  • 장은영;이성수;김원후
    • 한국통신학회논문지
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    • 제16권10호
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    • pp.914-924
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    • 1991
  • 랜덤한 주파수도약을 실현하기 위해 기존의 PLL(Phase Locked Loop)방식이 많이 사용 되었으나 locking time이 소요되는바, 출력주파수의 졍현파형을 직접 합성하는 직접 디지털 주파수 합성방식을 이용하여 이러한 단점을 없앨 수 있으나. 기존의 위상누적 방식을 이용한 직접 디지털 주파수 합성방식에서는 합성 파형상에 위상 왜곡이 수반되어 불요잡음이 크게 나타났다. 이러한 단점을 개선하기 위해 위상누적 방식에 관한 이론을 고찰하고 새로운 방식의 이론식을 유도하여 이에 적합한 시스템을 구성하였다. 또한 합성된 출력주파수의 정현파형에 대한 스펙트럼 분석과 PN(pseudo Noise)부호를 사용한 순시적인 주파수 도약상태의 확인 결과, 기존의 위상누적 방식보다 불요잡음 전력레벨이 10~25dB 줄고 주파수 대역도 420kHz까지 확장 가능함을 알았다.

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The Effects of Myrtle (Myrtus communis) and Clindamycin Topical Solution in the Treatment of Mild to Moderate Acne Vulgaris: A Comparative Split-Face Study

  • Salmanian, Mahboobeh;Shirbeigi, Laila;Hashem-Dabaghian, Fataneh;Mansouri, Parvin;Azizkhani, Mohammad;Alavi, Shiva;Ghobadi, Ali
    • 대한약침학회지
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    • 제23권4호
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    • pp.220-229
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    • 2020
  • Objectives: Although Acne vulgaris is a chronic skin disease, which its standard treatment causes therapeutic limitations and some common adverse effects, medicinal plants can be effective in treatment with low adverse effects as combination therapy. Myrtle (Myrtus Communis) has some beneficial properties, which has been administered topically and orally for some skin diseases in Persian medicine. This study aimed to compare the efficacy and safety of Myrtle formula and 1% clindamycin topical solution. Methods: This was a split-face clinical trial that was done on 55 patients with mild to moderate acne vulgaris for 16 weeks. The patients received topical Myrtle solution to the right side of the face (group 1) and clindamycin solution to the left side (group 2) twice daily for 12 weeks. All participants were examined for the acne severity index (ASI) and total acne lesions counting (TLC) at certain times during the study. Then, they stopped using them for four weeks. They also did not take the drug in the final four weeks of the study. Results: Forty-eight patients completed the study for 16 weeks; 40 (83.2%) patients were female and the rest of them were male. The mean age and standard deviation were 25.62 ± 7.62 years. After 12 weeks, the percentage changes of comedones, inflammatory lesions, ASI and TLC were significantly reduced in both groups (p < 0.001). The percentage change of inflammatory lesions and ASI decrease was significantly higher in the group 1 (p = 0.03). There was no significant difference in the incidence of side effects between the two groups. There was a more significant decrease in sebum percentage change in the group 1 (p = 0.003). Conclusion: Myrtle lotion was effective and safe for the treatment of mild to moderate acne vulgaris.

Efficient Synthesis of hypho-2,5-$S_2B_7H_{11}$ and Preparation of New nido-, arachno-, and hypho-Metalladithiaborane Clusters Derived from Its Anion hypho-$S_2B_7H_{10}{^-}$

  • 강창환;김성준;고재정;강상욱
    • Bulletin of the Korean Chemical Society
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    • 제16권11호
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    • pp.1067-1074
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    • 1995
  • Reaction of arachno-S2B7H8- with either THF or 1,2-dimethoxyethane upon refluxing condition results in the formation of the previously known compound hypho-S2B7H10-. Protonation of hypho-S2B7H10- with HCl/Et2O generates hypho-2,5-S2B7H11 in good yield. This hypho-S2B7H10- anion has been employed to generate a series of new nido-, arachno-, and hypho-metalladithiaborane clusters. Reaction of the anion with Cp(CO)2FeCl results in direct metal insertion and the formation of a complex containing the general formula (η5-C5H5)FeS2B7H8. Spectroscopic studies of nido-6-CpFe-7,9-S2B7H8 Ⅰ demonstrated that compound Ⅰ was shown to have an nido-type cage geometry derived from an octadecahedron missing one vertex, with the iron atom occupying the three-coordinate 6-position in the cage and the two sulfurs occupying positions on the open face of the cage. Reaction of hypho-S2B7H10- with CoCl2/Li+[C5H5]- gave the previously known complex arachno-7-CpCo-6,8-S2B6H8 Ⅱ. Also, the reaction of the anion with [Cp*RhCl2]2 gave the complex arachno-7-Cp*Rh-6,8-S2B6H8 Ⅲ, the structure of which was shown to be that of complex Ⅱ. The similarity of the NMR spectra of Ⅱ and Ⅲ suggest that Ⅲ adopts cage structure similar to that previously confirmed for Ⅱ. A series of 9-vertex hypho clusters in which the sulfur atoms are bridged by different species isoelectronic with a BH3 unit, such as HMn(CO)4 or SiR2 have been prepared. Compounds Ⅳ,Ⅴ and Ⅵ are each 2n+4 skeletal electron systems and would be expected according to skeletal electron counting theory to adopt hypho-type polyhedral structures derived from an icosahedron missing three vertices. The complex hypho-1-(CO)4Mn-2,5-S2B6H9 Ⅳ was obtained by the reaction of the anion with (CO)5MnBr and has been shown from spectroscopic data to consist of a (CO)4Mn fragment bound to the two sulfur atoms S2 and S5 of hypho-S2B7H10-. Also, similar hypho-type complexes hypho-1-R2Si-2,5-S2B6H8 (R=CH3 Ⅴ, R=C6H5 Ⅵ) have been prepared from the reaction of hypho-S2B7H10- with R2SiHCl.

회전 유리판과 3D 프린터를 이용한 교육용 마흐젠더 간섭계 제작 (Fabrication of a Mach-Zehnder interferometer for education using a rotating glass plate and a 3D printer)

  • 장성훈;주영구
    • 한국광학회지
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    • 제28권5호
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    • pp.213-220
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    • 2017
  • 3D 프린터와 반도체 레이저를 사용하여 정렬하기 쉽고 저렴한 교육용 마흐젠더 간섭계를 제작하는 방법을 제안하였다. 간섭계는 $165mm{\times}120mm{\times}57mm$ 크기의 몸체, 거울 마운트, 레이저 홀더, 광분할기 등으로 구성된다. 레이저 경로는 고무 밴드, 작은 금속 막대 및 나사로 구성된 4개의 거울 마운트로 조정하였다. 간섭무늬는 최종 단계에서 렌즈에 의해 확대되었다. 슬라이드 글라스의 굴절률은 간섭계 팔 중 하나에 삽입된 슬라이드 글라스가 회전하는 동안 이동하는 간섭무늬의 수를 계수함으로써 측정되었다. 굴절률을 구하는 식을 광경로차와 회전 각도의 함수로 찾았으며, 간섭계 실험에서 유리의 굴절률을 계산하는데 사용하였다. 간섭계의 한 팔에서 유리를 회전시키면 교실에서 움직이는 간섭무늬를 관찰하기 위해 고가이지만 사용되었던 정밀 스테이지가 필요 없게 된다. 따라서 이 논문에서 제안 된 3차원 프린터로 제작한 마흐젠더 간섭계는 경제성과 성능 때문에 교육에 매우 유용할 것으로 기대된다. 학생들이 3차원 프린터로 제작한 간섭계를 사용하여 유리의 굴절률과 빛의 파장을 측정하는 등의 정성적 및 정량적 연구를 수행 할 수 있을 것이다.