• Proceedings of the Computational Structural Engineering Institute Conference
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• 1994.10a
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• pp.152-159
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• 1994

One of the main objectives of the study is to propose a pratical and realistic reliability analysis by ETCM(Expected Total Cost Minimization). This study is intended to propose the safety assesment and capacity rating of existing reinforced concrete members by evaluating the safety evaluation index, that is RF(Rating Factor) from the results of the field test and inspection for 5 reinforced concrete bridges. ETCM method is used for the reliability analysis of the proposed models. The proposed reliability model and method are applied the safety assesment and system factors of reinforced concrete members.

• Journal of Power System Engineering
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• v.2 no.3
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• pp.60-67
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• 1998

Edge detection is the first step and very important step in image analysis. We cast edge detection as a problem in cost minimization. This is achieved by the formulation of a cost function that evaluates the quality of edge configurations. The cost function can be used as a basis for comparing the performances of different detectors. This cost function is made of desirable characteristics of edges such as thickness, continuity, length, region dissimilarity. And we use a simulated annealing algorithm for minimum of cost function. Simulated annealing are a class of adaptive search techniques that have been intensively studied in recent years. We present five strategies for generating candidate states. Experimental results(building image and test image) which verify the usefulness of our simulated annealing approach to edge detection are better than other operator.

• Journal of the Korean Society of Safety
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• v.29 no.6
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• pp.94-98
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• 2014

This study was intend to develop the optimal design method of suspension bridge by the reliability analysis based on minimization of life cycle cost(LCC). The reliability analysis was performed considering aleatory uncertainties included in the result of numerical analysis. The optimal design was estimated based on life-cycle cost analysis depending on the result of reliability analysis. As the effect of epistemic uncertainty, the safety index (beta), failure probability (pf) and minimum life cycle cost were random variables. The high-level distributions were generated, from which the critical percentile values were obtained for a conservative bridge design through sensitivity assessment.

• Korean Journal of Clinical Pharmacy
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• v.26 no.1
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• pp.59-69
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• 2016

Background: The subcutaneous formulation of biologic disease-modifying antirheumatic drugs (DMARDs) was preferred due to favored self-administration and would be an economical treatment option for patients with rheumatoid arthritis. This study was to compare the economic impact of biologic DMARDs administered by subcutaneous injection in patients with rheumatoid arthritis who had inadequate response to conventional DMARDs. Methods: The cost-minimization analysis was conducted to estimate the lifetime health care costs of treatment sequences with subcutaneous biologic DMARDs as first-line therapy from a health care system perspective. The Markov model was developed to represent the transitions through treatment sequences based on American College of Rheumatology response rate and discontinuation rate. The health care costs comprised the cost of medications, administration, dispensing, outpatient visits, test/diagnostic examination, palliative therapy and treatment of serious infection. All costs were expressed in 2016 Korean Won (KRW) and discounted at 5%. Results: The mean lifetime health care cost per patient was lowest in the etanercept sequence, which was estimated at KRW 63,441,679. The incremental costs of the treatment sequence started with adalimumab, golimumab, abatacept, and tocilizumab were KRW 7,985,730, KRW 4,064,669, KRW 2,869,947, and KRW 4,282,833, respectively, relative to etanercept sequence. These differences in costs mainly were attributable to medication costs. One-way and probabilistic sensitivity analyses confirmed that etanercept represented the option with the lowest cost compared with comparators. Conclusion: This study found that etanercept is likely a cost-saving treatment option among subcutaneous biologic DMARDs in patients with rheumatoid arthritis.

• Pediatric Infection and Vaccine
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• v.15 no.1
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• pp.20-29
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• 2008

The basis of the economic evaluation of vaccination is the balance between the use of the resources (input) and the improvements that result from the vaccination (output). Techniques used for economic evaluation of vaccination are cost analysis, cost-minimization analysis, cost-effectiveness analysis, cost-utility analysis and cost-benefit analysis. Cost analysis seeks to characterize the costs of a given vaccination program. Cost-effective analysis is to helps policy-makers decide on the best use of allocated resources, whether cost-benefit analysis is to helps policy-makers decide on the overall allocation of resources. Cost-utility analysis is a specific form of cost-effective analysis in which outcomes are reduced to a common denominator such as the quality-adjusted life year (QALY) or disability-adjusted life year (DALY). Many economic analyses have been conducted on vaccines in the world, but there have been a little studies on economic evaluation on vaccines in Korea. This paper reviewed the methodology used to economic evaluation on vaccines and immunizations and addressed some examples of the methods.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.25 no.10
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• pp.28-37
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• 2011

Though Korea has introduced CBP(Cost Based pool) power trading system since 2001, long-term Generation system planning has been executed by government for Cost minimization every 2 years. Until currently the model which is used for Generation system planning and best-mix only considers cost minimization and total yearly or quarterly electricity demand every year. In a view point of one day power supply operation, technical characteristics, like the ramp up/down rate of total generation system, minimum up/down time and GFRQ(Governor Free Response Quantity), are very important. this paper analyzes Optimal Fuel-Mix for 2022 Korea generation system satisfying these constraints of each fuel type and considering pump storage plants, construction cost and $CO_2$ emission charge Using MILP(Mixed Integer Linear Programming) method. Also the sensitivity analysis which follows in future power industry environmental change accomplished.

• Convergence Security Journal
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• v.13 no.1
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• pp.11-17
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• 2013

In this paper, the information security requirements in the mobile ad-hoc network(MANET) are presented, and the algorithm to establish the protection node(gateway) is proposed to prevent the distributed denial of service(DDoS). The information security technology and security threats in the MANET are presented, and protection node is decided to minimize the total cost through the sending nodes and receiving nodes by way of protection node. To set up the protection node, the minimization algorithms of maximum cost and the average cost between the protection node and receiving nodes are compared with the optimal solutions, in which optimal solution is found out by all enumeration method. From the results, the total cost between the sending and receiving nodes is minimized under the average cost minimization algorithm rather than the using of the maximum cost.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.7
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• pp.51-58
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• 2010

Wireless Mesh Network has drawn much attention due to wide area service coverage with low system cost. However, there is a bottleneck problem in wireless mesh network since the traffic is aggregated into a gateway. Placement of multi-radio can easy the bottleneck problem, but without careful design it results in unnecessary system cost increasement. In this paper, we propose a system cost minimization through differential antenna placement where optimum antenna placement is determined by the required wireless link capacity. With CPLEX program, optimum number of antennae is determined as a function of local user traffic and gateway capacity. From numerical analysis, it is confirmed that our proposed model can solve bottleneck problem, and at the same time save the system cost.

• Journal of Energy Engineering
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• v.6 no.2
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• pp.188-197
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• 1997

MARKAL model was applied for assessment of iron and steel technology for the year of 2032 considering cost and environmental effects based on 1992. Technology, energy and material flows were analyzed in iron and steel sector. Reference iron and steel system was designed according to this analysis. Six scenarios were developed considering cost and environmental limitations such as CO$_2$emission control and SOx reduction cost. Competitiveness of technologies in iron and steel sector was assessed under different environmental limitations with cost minimization. Through this study, it was confirmed that MARKAL model can be applied to technology assessment in the field of iron and steel industry.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.10a
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• pp.1090-1097
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• 2008

This study conducted the decision method of lateral flow in abutment structures founded on the soft soils and the reliability analysis on the foundation pile for abutment. On the basis of the results, this study proposed the reliability design model. Reliability analysis was conducted by applying second moment method, point estimation method, and expected total cost minimization to lateral movement index, lateral movement decision index, modified lateral movement decision index, and circular failure safety factor for the decision criteria of lateral flow. The reliability index by analysis method had a similar tendency each other. Point estimation method was found as a practical method in the aspect of convenience because it could conduct the analysis only by mean and standard deviation as well as the partial derivative on random variables was not necessary. Optimum reliability index and optimum safety according to increasing in failure factors and load ratio were analyzed and loads and resistance factors of the design criteria of optimum reliability were estimated. It presented rational design model which can consider construction level and stability and economical efficiency overall.