• Bulletin of the Korean Chemical Society
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• 제26권11호
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• pp.1776-1782
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• 2005

ZnSe/ZnS, UV-blue luminescent core shell quantum dots, were synthesized via a thermal decomposition reaction of organometallic zinc and solvent coordinated Selenium (TOPSe) in a hot solvent mixture. The synthetic conditions of the core (ZnSe) and the shell (ZnS) were independently studied at various reaction temperature conditions. The obtained colloidal nanocrystals at corresponding temperatures were characterized for their optical properties by UV-vis, room temperature solution photoluminescence (PL) spectroscopy, and further obtained powders were characterized by XRD, TEM, and EDXS analyses. The synthetic temperature condition to obtain the best PL emission intensity for the ZnSe core was 300 ${^{\circ}C}$, and for the optimum shell capping, the temperature was 135 ${^{\circ}C}$. At this temperature, solution PL spectrum showed a narrow emission peak at 427 nm with a PL efficiency of 15%. In addition, the measured particle sizes for the ZnSe/ZnS nanocomposite via TEM were in the range of 5 to 12 nm. Furthermore, we have synthesized water-soluble ZnSe/ZnS nanoparticles by capping the ZnSe/ZnS hydrophobic surface with mercaptoacetate (MAA) molecules. For the obtained aqueous colloidal solution, the UV-vis spectrum showed an absorption peak at 250 nm, and the solution PL emission spectrum showed a peak at 425 nm, which is similar to that for hydrophobic quantum dot ZnSe/ZnS. However, the calculated PL efficiency was relatively low (0.1%) due to the luminescence quenching by water and MAA molecules. The capping ligand was also characterized by FT-IR spectroscopy, with the carbonyl stretching peak in the mercaptoacetate molecule appearing at 1575 $cm ^{-1}$. Finally, the particle sizes of the MAA capped ZnSe/ZnS were measured by TEM, showing a range of 12 to 17 nm.

• 대한기계학회논문집B
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• 제33권6호
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• pp.403-410
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• 2009

This paper proposes a new approach to find the optimum ratios between sizes of the heat exchangers of the heat recovery steam generator (HRSG) system with limited size to maximize the efficiency of the steam turbine (bottom) cycle of combined cycle power plants (CCPP), but without performing the bottom cycle analysis. This could be achieved by minimizing the unavailable exergy (the sum of the destroyed and the lost exergies) resulted from the heat transfer process of the HRSG system. The present approach is relatively simple and straightforward because the process of the trial-and-error method, typical in performing the bottom cycle analysis for the system optimization, could be avoided. To demonstrate the usefulness of the present method, a single-stage HRSG system was chosen and the optimum evaporation temperature was obtained corresponding to the condition of the maximum useful work. The results show that the optimum evaporation temperature based on the present exergy analysis appears similar to that based on the bottom cycle analysis. Also shown is the dependency of size (NTU) ratios between the heat exchangers on the inlet gas temperature, which is another important factor in determining the optimum condition once overall size of the heat recovery steam generator is given. The present approach turned out to be a useful tool for optimization of the singlestage HRSG systems and can easily be extended to multi-stage systems.

• Journal of Preventive Medicine and Public Health
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• 제32권4호
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• pp.491-498
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• 1999

Objectives : To determine the relations between seven blood lipids such as total cholesterol(TC), triglyceride(TG), HDL-cholesterol(HDL), LDL-cholesterol(LDL), apolipoprotein A-1(Apo A1), apolipoprotein B(Apo B) and lipoprotein(a)(Lp(A)) and the coronary heart diseases(CHD), the quantitative techniques of meta-analysis were applied to studios of blood lipids and CHD in Koreans. Methods : We searched the Korean and the English literature published from 1980 to August, 1997 by manual search and bibliography review. Information on sample size, study design, participant characteristics(gender, age) and blood lipid levels were abstracted by reviewers using inclusion criteria. Estimates of the effect sizes of blood lipid levels on CHD in Koreans and corresponding 95% confidence intervals were calculated using random-effect models. Results : We identified 16 case-control studies to apply meta-analysis. The overall effect sizes for CHD were 20.3(95% CI: 14.23-20.22) in TC, 24.8(95% CI: 12.6-36.86) in TG, 15.16(95% CI: 3.99-26.33) in LDL, -3.48(95% CI: -5.79 - -1.17) in HDL, -9.78(95% CI: -16.98 - -2.58) in Apo-a1, 17.88(95% CI: 9.72-26.05) in Apo B and 18.95(95% CI: 17.88-20.02) in Lp(a). Conclusions : Our results suggested that seven blood lipids were significantly associated with CHD in Koreans. Well-designed and prospective studies between blood lipids and CMD in Koreans should be peformed.

• 응용통계연구
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• 제24권6호
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• pp.1271-1284
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• 2011

본 논문에서는 위치와 척도모수가 모두 알려지지 않은 역가우스분포에 대한 적합도 검정으로 기존에 개발된 엔트로피 기반 검정을 확장한 쿨백-라이블러 정보 기반 적합도 검정을 소개한다. 역가우스분포에 대한 단순 또는 복합 영가설을 검정하기 위한 4가지 형태의 검정통계량을 제시하고 검정통계량의 계산에 사용할 표본크기에 따른 윈도크기와 기각값을 모의실험을 통해 결정하여 표의 형태로 제공한다. 검정력 분석을 위해 수행한 모의실험의 결과에서 위치와 척도모수가 모두 알려진 역가우스분포에 대한 쿨백-라이블러 정보 기반 적합도 검정은 모든 대립분포와 표본크기에서 EDF 검정들보다 좋은 검정력을 가지는 것으로 나타난다. 위치모수 또는 척도모수만 알려진 역가우스분포에 대한 쿨백-라이블러 정보 기반 적합도 검정은 모든 대립분포에 대해서 표본크기가 커짐에 따라 검정력이 증가하는 경향을 보인다. 위치와 척도모수가 모두 알려지지 않은 역가우스분포에 대한 쿨백-라이블러 정보 기반 적합도 검정은 대체적으로 엔트로피 기반 검정과 비슷한 수준의 검정력을 보이는 것으로 나타나고 이 결과를 통해서 두 검정은 동일함을 확인할 수 있다.

• 응용통계연구
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• 제21권2호
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• pp.291-299
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• 2008

동일 개체가 여러 시점에서 반복되어 측정될 때, 측정값들 간에 종속성을 예상할 수 있다. 본 논문은 한 개체의 이가 반응변수가 g개 시점에서 관측될 때, 종속적인 g개 이 가변수들의 다변량 분포로부터 각 시점에서의 주변분포의 동질성을 파악하기 위한 로짓모형을 제시하고 자료분석 방법을 제공하고자 한다. 모형과 관련된 가정으로 반복측정이 행해지는 g개 시점은 각기 서로 다른 요인 또는 공변량의 결합수준들로 구성된다고 가정한다. 또한, 모형에서 고려된 처치들이 반복측정에 기인하는 서로 다른 크기의 실험 단위들에 행해질 때 모수들을 추정하기 위한 방법으로 가중최소제곱법을 다루고 있다. 여기서 가중최소제곱법은 반응변수들의 종속성으로 인한 공분산 구조에 근거한 모형내 모수들의 효과를 효율적으로 추론하기 위해 이용된다. 제시된 모형은 주변로짓을 이용함으로써 단순히 주변확률분포의 동질성에 대한 검정뿐만 아니라 모형의 타당성 및 요인들의 수준변화에 따른 효과를 파악하기 위한 효과적인 모형임을 보여준다.

• 한국지반신소재학회논문집
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• 제12권1호
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• pp.51-61
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• 2013

본 논문에서는 지오텍스타일 공극 크기 분포를 이미지 분석방법을 이용하여 정량적으로 산출하였다. 연구과정은 실내시험을 통해 지오텍스타일-지오멤브레인 층으로 된 재료를 에폭시 레진으로 포화시킨 후, 양생, 절단하여 그 표면을 디지털 광학현미경으로 관찰하고 정량화함으로 이루어졌다. 여기서는 재료공학에서 주로 사용하는 공간학(stereology)의 개념을 사용하였으며, 지오텍스타일 필라멘트에 의해 둘러싸인 공극의 크기를 최대내접공극크기분포(LIOS)로 표현하였다. 지오텍스타일 내부 축적빈도 50%에 해당하는 공극직경이 압축응력이 10kPa에서 300kPa로 증가함에 따라 $45{\mu}m$가량 감소하였으며, 다시 압축응력을 10kPa로 되돌렸을 경우 초기치의 90%정도 수준으로 회복하였다. 마찰형 지오멤브레인 표면에서 연직응력 100, 300 kPa을 받으며 전단되었을 경우 평균 공극의 크기가 각가 32, 16.5% 감소하였다. 본 논문의 시험 및 분석 결과는 지오텍스타일 내부의 최대내접공극 크기분포가 표면거칠기가 다른 지오멤브레인 표면에서 압축 및 인터페이스 전단됨에 따라 어떻게 변화하는지를 보여준다.

• 약학회지
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• 제55권1호
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• pp.39-44
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• 2011

Many reports indicate that $18{\beta}$-glycyrrhetinic acid ($18{\beta}$-GA) from Glycyrrhizae Radix has anti-inflammatory and immunoregulatory activities, whereas reports regarding anticancer activity of the compound are few. In present study, we investigated antitumor effect of $18{\beta}$-GA on tumor caused by A549 cancer cell in mice. Data resulting from the cytotoxicity assay showed that $18{\beta}$-GA caused killing of A549 cells. $LD_{50}$ values of $18{\beta}$-GA were app. 180 ${\mu}M$ and 80 ${\mu}M$, corresponding to 48 hr- and 72 hr-treatments, displaying that the killing activity was more effective as the $18{\beta}$-GA treatment was prolonged. Based on these data, antitumor effect of $18{\beta}$-GA was tested in nude mice. For induction of the tumor, A549 ($3{\times}10^6$ cells/mouse) was injected subcutaneously into the lateral abdomen of nude mice (Balb/c nu/nu). To determine the antitumor effect, nude mice with tumor were given $18{\beta}$-GA (1 mg/200 ${\mu}l$/mouse) intraperitoneally every three days for four times. Tumor-sizes were measured with a caliper for a period of 24 days. Results showed that the $18{\beta}$-GA treatment reduced the tumor-sizes (P<0.05) as compared with negative control nude mice that received diluent (DPBS). The reduction degree was greater than reduction degree by doxorubicin (60 ${\mu}g$/mouse), and the pattern of reduction was almost sustained during the entire period of the observation. In conclusion, our studies demonstrate that $18{\beta}$-GA has antitumor activity to the A549 cancer cell-caused tumor.

• 패션비즈니스
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• 제24권1호
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• pp.102-116
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• 2020

After its introduction in Korea, nail art is becoming active, especially among women in their 20s and 30s who are interested in fashion and beauty. Although self-nail tips are available online in various designs for each brand that is currently on the market, these designs and sizes of self-nail tips on the market are different for each age group. Since the design or size is not suggested for the different situations, there are difficulties in purchasing products that match the shape and size of nails of consumers. In this study, frequency analysis was performed using 'SPSS statistics 21.0 for windows program' to analyze data obtained by direct measurement method and 3D scanner measurement method for Korean women in their 20s. For comparative analysis between direct and 3D scanner measurements, a corresponding sample, 'T-test', was performed. As a result, we proposed the standardization of nail tip size after comparative analysis between direct measurement and 3D scanner measurement. Previous studies have been proceeding with direct measurement method. However, this study introduced a 3D scanner measurement method in the nail field and attempted the standardization of nail size by age group of Korean women. Importantly, this sutdy suggests standardization of nail tip size among missing body sizes.

• Toxicological Research
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• 제28권4호
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• pp.209-216
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• 2012

The biological activity of particles is largely dependent on their size in biological systems. Dispersion in the aqueous phase has been both a critical impediment to and a prerequisite for particle studies. Carbon black has been used as a surrogate to investigate the biological effects of carbonaceous particles. Here, biocompatible methods were established to disperse carbon black into ultrafine and fine particles which are generally distinguished by the small size of 100 nm. Carbon black with a distinct particle size, N330 and N990 were suspended in blood plasma, cell culture media, Krebs-Ringer's solution (KR), or physiological salt solution (PSS). Large clumps were observed in all dispersion preparations; however, sonication improved dispersion - averaged particle sizes for N330 and N990 were $85.0{\pm}42.9$ and $112.4{\pm}67.9$ nm, respectively, in plasma; the corresponding sizes in culture media were $84.8{\pm}38.4$ and $164.1{\pm}77.8$ nm. However, sonication was not enough to disperse N330 less than 100 nm in either KR or PSS. Application of Tween 80 along with sonication reduced the size of N330 to less than 100 nm, and dispersed N990 larger than 100 nm ($73.6{\pm}28.8$ and $80.1{\pm}30.0$ nm for N330 and $349.5{\pm}161.8$ and $399.8{\pm}181.1$ nm for N990 in KR and PSS, respectively). In contrast, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) exhibited little effect. Electron microscopy confirmed the typical aciniform structure of the carbon arrays; however, zeta potential measurement failed to explain the dispersibility of carbon black. The methods established in this study could disperse carbon black into ultrafine and fine particles, and may serve as a useful model for the study of particle toxicity, particularly size-related effects.

• Geomechanics and Engineering
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• 제28권5호
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• pp.521-529
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• 2022

This research work deals with the development of air pluviation method for preparing uniform sand specimens for conducting large scale laboratory testing. Simulating real field conditions and to get reliable results, air pluviation method is highly desirable. This paper presents a special technique called air pluviation or sand raining technique for achieving uniform relative density. The apparatus is accompanied by a hopper, shutters with different orifice sizes and numbers and set of sieves. Before using this apparatus, calibration curves are drawn for relative density against different height of fall (H) and shutter sizes. From these calibration curves, corresponding to the desired relative density of 60%, the shutter size of 13mm and height of fall of 457.2 mm, are selected and maintained throughout the pluviation process. The density obtained from the mobile pluviator is then verified using the Dynamic Cone Penetrometer (DCP) test where the soil is poured in the box using defined shutter size and fall height. The results obtained from the DCP test are averaged as 60±0.5 which was desirable. The mobile pluviator used in this research is also capable of obtaining relative densities up to 90%. The instrument is validated using experimental and numerical approach. In numerical study, Plaxis 3D software is used in which the soil mass is defined by 10-Node tetrahedral elements and 6-Node plate is used to simulate plate behavior in the validation phase. The results obtained from numerical approach were compared with that of experimental one which showed very close correlation.