• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.469-472
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• 2015

Cryptogenic organizing pneumonia (COP) is an inflammatory lung disease involving the distal bronchioles, respiratory bronchioles, bronchiolar ducts, and alveolae. The etiology is usually unknown; however, there are several known causes and associated systemic diseases. Corticosteroid therapy is the best treatment option and the prognosis of COP is good, with recovery in up to 80% of patients. We described a patient with in-operable hepatocellular carcinoma (HCC) undergoing chemoembolization with doxorubicin in a drug-eluting bead (DEB). COP developed in the patient after chemoembolization but resolved spontaneously in several months.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.401-407
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• 2015

Cryptogenic organizing pneumonia (COP) is an idiopathic interstitial pneumonia characterized by a subacute course and favorable prognosis with corticosteroids. However, some patients show resistance to steroids. Macrolides have been used with success in those patients showing resistance to steroids. A few reports showed treatment failure with macrolides in patients with COP who were resistant to steroids. In this report, we described two cases of COP who showed different responses to clarithromycin. One recovered completely, but the other gradually showed lung fibrosis with clarithromycin.

• 한국수소및신에너지학회논문집
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• 제20권6호
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• pp.526-533
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• 2009

In this paper, cycle performance analysis of $CO_2-C_3H_8$ (R744-R290) cascade refrigeration system with internal heat exchanger is presented to offer the basic design data for the operating parameters of the system. The operating parameters considered in this study include subcooling and superheating degree and gas cooling pressure and evaporating temperature in the propane (R290) low temperature cycle and the carbon dioxide (R744) high temperature cycle. The main results were summarized as follows : The COP of cascade refrigeration system of $CO_2-C_3H_8$ (R744-R290) increases with the increasing subcooling degree, but decreases with the increasing superheating degree. The COP of cascade refrigeration system increases with the increasing evaporating temperature, but decreases with the increasing gas cooling pressure. Therefore, superheating and subcooling degree, compressor efficiency, evaporating temperature and gas cooling pressure of $CO_2-C_3H_8$ (R744-R290) cascade refrigeration system have an effect on the COP of this system.

• Journal of Advanced Marine Engineering and Technology
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• 제31권5호
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• pp.558-566
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• 2007

The performance characteristics of water-chilling heat pump using $CO_2$ with respect to variation of refrigerant charge amount was investigated experimentally. An experimental apparatus is consisted of a compressor, a gas cooler, an expansion valve, an evaporator and a liquid receiver. All heat exchangers used in the test rig are counter-flow-type heat exchangers with concentric dual tubes, which are made of copper. The gas cooler and the evaporator consist of 6 and 4 straight sections respectively arranged in parallel, each has 2400 mm length. The experimental results summarize as the followings : As the refrigerant charge ratio of $CO_2$ heat pump system increases, the discharge pressure and compressor ratio increases, but mass flow rate of refrigerant decreases. Also the compressor work increases with the increase of refrigerant charge ratio. However, the heating and cooling capacity of $CO_2$ heat pump decreases as the refrigerant charge ratio increases. The maximum heating COP of $CO_2$ heat pump system presented at 0.25 refrigerant charge ratio. It is possible to confirm the optimum charge ratio of $CO_2$ heat pump system by the viewpoint of heating COP.

• 대한기계학회논문집B
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• 제32권6호
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• pp.454-462
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• 2008

Since operating conditions are significantly different for heating and cooling mode operations in a $CO_2$ heat pump system, it is difficult to optimize the performance of the $CO_2$ cycle. In addition, the performance of a $CO_2$ heat pump is very sensitive to outdoor temperature and gascooler pressure. In this study, the cooling and heating performances of a variable speed $CO_2$ heat pump with a twin-rotary compressor were measured and analyzed with the variations of EEV opening and compressor frequency. As a result, the cooling and heating COPs were 2.3 and 3.0, respectively, when the EEV opening was 22%. When the optimal EEV openings for heating and cooling were 28% and 16%, the cooling and heating COPs increased by 3.3% and 3.9%, respectively, over the COPs at the EEV opening of 22%. Beside, the heating performance was more sensitive to EEV opening than the cooling performance. As the compressor speed decreased by 5 Hz, the cooling COP increased by 2%, while the heating COP decreased by 8%.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2007년도 동계학술발표대회 논문집
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• pp.441-446
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• 2007

This present study is to evaluate the cooling performance of a water-to-refrigerant ground source heat pump system(GSHP) under actually operating condition. 1 unit is selected among 10 units of the GSHP in the building to analyze the performance. The average cooling COP of the GSHP at the part load of 64% is 8.2, overall system COP is 6.19. In the GSHP system, the cooling temperature of the condenser is lower compared to the air source heat pump system. Conclusively, the cooling performance of the GSHP is higher than the air source heat pump system by 80%.

• 설비공학논문집
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• 제10권3호
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• pp.292-302
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• 1998

In this study, 14 refrigerant mixtures composed of R32, R125, R134a, R143a, R152a, and R1270(Propylene) were tested in a breadboard heat pump in an attempt to replace R22 used in most of the residential air conditioners and heat pumps. The heat pump was of 1 ton capacity and water was employed as the secondary heat transfer fluids. All tests were conducted under ARI test A condition. Ternary mixtures composed of R32, R125, and R134a were shown to have 4∼5% higher COP and capacity than R22 and hence they seem to be very promising candidates to replace R22. On the other hand, ternary mixtures containing R125, R134a, and R152a have lower COP and capacity than R22. R32/R134a binary mixtures show a 7% increase in COP and have the similar capacity to that of R22 and hence they are also good candidates to replace R22. Special care must be exercised when a suction line heat exchanger is used with these mixtures in air conditioners. Finally, the compressor discharge temperatures of all mixtures tested were lower than those of R22 by 15.g∼34.7t, which indicates that these mixtures would offer better system reliability and longer life time than R22.

• 설비공학논문집
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• 제19권2호
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• pp.162-168
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• 2007

This paper presents the effects of thermoelectric module arrangement on the cooling performance of an air conditioner using thermoelectric module. A prototype of air cooling system, employing several thermoelectric modules, has been designed and built. The evaporative cooling technique is adopted for hot side of the module. The number of thermoelectric module in the system has been varied in the range of $2{\sim}8$. The optimal operation conditions, such as input power to the thermoelectric module, fans and pump, have been determined for each arrangement of the system and the cooling performance has been compared under the optimal operation. It is found that both cooling capacity and COP are increased as the number of thermoelectric module increased. It is also found that cooling capacity can be improved by connecting the thermoelectric modules in series than in parallel, while the COP is little affected.

• 설비공학논문집
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• 제27권10호
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• pp.497-505
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• 2015

The evaporating temperature range required for the low temperature freezing system is from $-50^{\circ}C$ to $-30^{\circ}C$. Since it is difficult to keep the required capacity in a cabinet, it is advantageous to design the system using a cascade refrigeration system. Use of carbon dioxide and ammonia would be advantageous since ammonia is an environment-friendly working fluid and has a high capacity for performance improvement. To investigate the performance characteristics of the R744-R717 cascade refrigeration system, a theoretical model was developed and performance was analyzed according to cascade heat exchanger operating temperature. The optimal cascade R744 condensing temperature was $-5^{\circ}C$, and maximum COP was 1.13 when the temperature difference of the cascade heat exchanger was $5^{\circ}C$. In addition, the total system COP increased by 1.17 when the cascade temperature gap was $3^{\circ}C$ at the middle temperature of $-7.5^{\circ}C$.

• 설비공학논문집
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• 제23권7호
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• pp.513-519
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• 2011

The object of this study is to investigate the performance characteristics of refrigerators using a single-circuit multi cycle and a bypass two-circuit multi cycle. Each refrigeration cycle was tested by varying secondary fluid mass flow rate and temperature. Based on the experimental data, the optimum refrigerant charge was 48 g and the COP at the optimum secondary fluid mass flow rate was 1.53 for the single-circuit multi cycle. For freezer(F)-only mode, both the single-circuit multi cycle and the bypass two-circuit multi cycle were operated at overcharge conditions, resulting in an increase of the secondary fluid mass flow rate. The maximum COPs of the single-circuit multi cycle and the bypass two-circuit multi cycle were 1.22 and 1.35, respectively. The COP increased by 10.7% with the application of the bypass two-circuit multi cycle.