• Title/Summary/Keyword: conventional procedure

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Automated Protein-Expression Profiling System using Crude Protein Direct Blotting Method

  • Kobayashi, Hironori;Torikoshi, Yasuhiro;Kawasaki, Yuko;Ishihara, Hideki;Mizumoto, Hiroshi
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.2356-2361
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    • 2003
  • Proteome research in the medical field is expected to accelerate the understanding of disease mechanism, and to create new diagnostic concept. For protein profiling, this paper proposes a new methodology named CPDIB (Crude Protein Direct Blotting). In the CPDIB procedure, crude protein sample is directly immobilized on a membrane and the expression of protein molecules in the sample are analyzed quantitatively by using a special device called ImmobiChip, where the membrane is used as a field of the immune reaction. The over-all structure of the ImmobiChip is based on the conventional Slot blot device. Mechanical improvement in the air-tightness of the case holding the membrane realizes the direct blotting and results in high performance of stability in the immune reaction. In the measurement of multiple proteins, a dispensing robot is used for increasing the efficiency of handling of liquid. Cooperation of the dispensing robot with the ImmobiChip for immobilizing proteins realizes automated and stable performance of the CPDIB procedure. This paper shows the evaluation of the air-tightness of the ImmobiChip, the ability of analyzing proteins using the CPDIB procedure and the performance of the automated equipment.

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A Simplified Procedure for Performance-Based Design

  • Zareian, Farzin;Krawinkler, Helmut
    • Journal of the Earthquake Engineering Society of Korea
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    • v.11 no.4
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    • pp.13-23
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    • 2007
  • This paper focuses on providing a practical approach for decision making in Performance-Based Design (PBD). Satisfactory performance is defined by several performance objectives that place limits on direct (monetary) loss and on a tolerable probability of collapse. No specific limits are placed on conventional engineering parameters such as forces or deformations, although it is assumed that sound capacity design principles are followed in the design process. The proposed design procedure incorporates different performance objectives up front, before the structural system is created, and assists engineers in making informed decisions on the choice of an effective structural system and its stiffness (period), base shear strength, and other important global structural parameters. The tools needed to implement this design process are (1) hazard curves for a specific ground motion intensity measure, (2) mean loss curves for structural and nonstructural subsystems, (3) structural response curves that relate, for different structural systems, a ground motion intensity measure to the engineering demand parameter (e.g., interstory drift or floor acceleration) on which the subsystem loss depends, and (4) collapse fragility curves. Since the proposed procedure facilitates decision making in the conceptual design process, it is referred to as a Design Decision Support System, DDSS. Implementation of the DDSS is illustrated in an example to demonstrate its practicality.

Hybrid Procedure for Aortic Arch Aneurysm: Arch Vessels Debranching andThoracic Endovascular Aortic Repair? -2 case Reports- (대동맥궁 대동맥류에서 Hybrid 술식의 적용 - 2예 보고 -)

  • Kim, Seok;Kwon, Oh-Choon;Lee, Sub;Cho, Jun-Woo;Bae, Chi-Hoon;Park, Ki-Sung
    • Journal of Chest Surgery
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    • v.43 no.5
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    • pp.529-533
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    • 2010
  • Conventional surgery for aortic arch aneurysms have many postoperative complications and a high mortality rate due to prolonged cardiopulmonary bypass time, especially in high risk patients. In this report, we present two cases of a hybrid procedure that involves open brachiocephalic bypass with concomitant endovascular arch stent grafting in high risk patients with distal aortic arch aneurysm.

An Adaptive Genetic Algorithm with a Fuzzy Logic Controller for Solving Sequencing Problems with Precedence Constraints (선행제약순서결정문제 해결을 위한 퍼지로직제어를 가진 적응형 유전알고리즘)

  • Yun, Young-Su
    • Journal of Intelligence and Information Systems
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    • v.17 no.2
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    • pp.1-22
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    • 2011
  • In this paper, we propose an adaptive genetic algorithm (aGA) approach for effectively solving the sequencing problem with precedence constraints (SPPC). For effective representation of the SPPC in the aGA approach, a new representation procedure, called the topological sort-based representation procedure, is used. The proposed aGA approach has an adaptive scheme using a fuzzy logic controller and adaptively regulates the rate of the crossover operator during the genetic search process. Experimental results using various types of the SPPC show that the proposed aGA approach outperforms conventional competing approaches. Finally the proposed aGA approach can be a good alternative for locating optimal solutions or sequences for various types of the SPPC.

Divergence-free algorithms for moment-thrust-curvature analysis of arbitrary sections

  • Chen, Liang;Liu, Si-Wei;Chan, Siu-Lai
    • Steel and Composite Structures
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    • v.25 no.5
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    • pp.557-569
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    • 2017
  • Moment-thrust-curvatures ($M-P-{\Phi}$ curves) are fundamental quantities for detailed descriptions of basic properties such as stiffness and strength of a section under axial loads required for accurate computation of the deformations of reinforced concrete or composite columns. Currently, the finite-element-based methods adopting small fibers for analyzing a section are commonly used for generating the $M-P-{\Phi}$ curves and they require large amounts of computational time and effort. Further, the conventional numerical procedure using the force-control method might encounter divergence problems under high compression or tension. Therefore, this paper proposes a divergence-free approach, combining the use of the displacement-control and the Quasi-Newton scheme in the incremental-iterative procedure, for generating the $M-P-{\Phi}$ curves of arbitrary sections. An efficient method for computing the strength from concrete components is employed, where the stress integration is executed by layer-based algorithms. For easy modeling of residual stress, cross sections of structural steel components are meshed into fibers for strength resultants. The numerical procedure is elaborated in detail with flowcharts. Finally, extensive validating examples from previously published research are given for verifying the accuracy of the proposed method.

Endoscopic Management of Cranial Arachnoid Cysts Using Extra-Channel Method

  • Kim, Myung-Hyun;Jho, Hae-Dong
    • Journal of Korean Neurosurgical Society
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    • v.47 no.6
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    • pp.433-436
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    • 2010
  • Objective : Arachnoid cysts (ACs) can be cured by making the definite and wide communication between the cyst and arachnoid space using endoscopy, but often it is impossible only through the usual working-channel (intra-channel) procedures. We discuss and propose a more valuable endoscopic technique with the presentation of our series of cases. Methods : We treated 9 patients with cortical AC in various locations with extra-channel endoscopic techniques. The patients ranged in age from 3 years to 60 years (mean age, 37.2 yrs). The follow-up period ranged from 12 to 26 months (mean follow-up duration, 17.2 months). All patients had large AC compressing the adjacent brain with clinical symptoms or signs. The authors performed extensive fenestration via single burr hole with the aid of endoscope. Being bypassed the rigid endoscope, through the space between the shaft of endoscope and guiding cannula (extra-channel method), fenestration procedures were done in the dry fields. Results : Eight (88.9%) patients had been treated successfully with endoscope. One patient required shunt procedure. Among the eight patients who were treated with endoscopic procedure, 6 patients (66.7%) showed cyst reduction, and two (22.2%) showed disappearance of cyst. Conclusion : We suggest that extra-channel method will be simple and easy to perform using more valuable instruments with wider working area, and may promise better results compared to the conventional intra-channel endoscopic procedures.

Identification of fractional-derivative-model parameters of viscoelastic materials using an optimization technique (최적화 기법을 이용한 점탄성물질의 유리미분모델 물성값 추정)

  • Kim, Sun-Yong;Lee, Doo-Ho
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.05a
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    • pp.1235-1242
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    • 2006
  • Viscoelastic damping materials are widely used to reduce noise and vibration because of its low cost and easy implementation, for examples, on the body structure of passenger cars, air planes, electric appliances and ships. To design the damped structures, the material property such as elastic modulus and loss factor is essential information. The four-parameter fractional derivative model well describes the nonlinear dynamic characteristics of the viscoelastic damping materials with respect to both frequency and temperature with fewer parameters than conventional spring-dashpot models. However the identification procedure of the four-parameter is very time-consuming one. An efficient identification procedure of the four-parameters is proposed by using an FE model and a gradient-based numerical search algorithm. The identification procedure goes two sequential steps to make measured FRFs coincident with simulated FRFs: the first one is a peak alignment step and the second one is an amplitude adjustment. A numerical example shows that the proposed method is efficient and robust in identifying the viscoelastic material parameters of fractional derivative model.

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Modeling and Autopilot Design of Blended Wing-Body UAV

  • Min, Byoung-Mun;Shin, Sung-Sik;Shim, Hyun-Chul;Tahk, Min-Jea
    • International Journal of Aeronautical and Space Sciences
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    • v.9 no.1
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    • pp.121-128
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    • 2008
  • This paper describes the modeling and autopilot design procedure of a Blended Wing-Body(BWB) UAV. The BWB UAV is a tailless design that integrates the wing and the fuselage. This configuration shows some aerodynamic advantages of lower wetted area to volume ratio and lower interference drag as compared to conventional type UAV. Also, BWB UAV may be increase payload capacity and flight range. However, despite of these benefits, this type of UAV presents several problems related to flying qualities, stability, and control. In this paper, the detailed modeling procedure of BWB UAV and stability analysis results using the linearized model at trim condition are represented. Finally, we designed the autopilot of BWB UAV based on a simple control allocation scheme and evaluated its performance through nonlinear simulation.

Development of the UPC-A Barcode Recognition Algorithm for Smartphone Applications (스마트 폰 어플리케이션 적용을 위한 UPC-A Bar code 인식 알고리즘 개발)

  • Lee, Sang-Joon;Lee, Sang-Yong;Lee, Young-Bum;Lee, Myoung-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.1
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    • pp.174-183
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    • 2011
  • This paper is about a bar code decoding algorithm developed for smart phone applications. The algorithm consists of bar code data extraction procedure, bar code signal estimation procedure, and bar code decoding procedure. To detect the peak bar code module, a DSTW had been applied because of its outstanding performance in ECG peak detection. In order to minimize errors due to non-uniform light effect, the proposed algorithm was acted as a baseline wandering filter based on module peaks detection. The algorithm had been tested to evaluate the performance under the conditions of blurring, non-uniformed light and white noises. The algorithm had shown excellent performance in reconstruction of bar code decoding, compared to other conventional methods. In order to show the possibility of applying the algorithm to a smart phone, a real UPC-A type 150 bar code pictures obtained from a smart phone camera was applied to the algorithm, achieving the correct recognition rate of 97.33%.

Fuzzy Sliding Mode Control of Nonlinear System Based on T-S Fuzzy Dynamic Model (T-S 퍼지 모델을 이용한 비선형 시스템의 퍼지 슬라이딩 모드 제어)

  • Yoo, Byung-Kook;Yang, Keun-Ho
    • Journal of the Korean Institute of Intelligent Systems
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    • v.14 no.1
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    • pp.112-117
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    • 2004
  • This paper suggests the design and analysis of the fuzzy sliding mode control for a nonlinear system using Takagi-Sugeno(T-S) fuzzy model. In this control scheme, identifying procedure that the input gain matrices in a T-S fuzzy model are manipulated into the same one is needed. The input disturbances generated in the identifying procedure are resolved by incorporating the disturbance treatment method of the conventional sliding mode control. The proposed control strategy can also treat the input disturbances that can not be linearized in the linearization procedure of T-S fuzzy modeling. Design example for the nonlinear system, an inverted pendulum on a cart, demonstrates the utility and validity of the proposed control scheme.